diff --git a/spanner/spanner_snippets/spanner/integration_test.go b/spanner/spanner_snippets/spanner/integration_test.go
index 47c2579ef6..f09032ffa2 100644
--- a/spanner/spanner_snippets/spanner/integration_test.go
+++ b/spanner/spanner_snippets/spanner/integration_test.go
@@ -167,6 +167,7 @@ func TestSample(t *testing.T) {
 	mustRunSample(t, createDatabase, dbName, "failed to create a database")
 	runSample(t, createClients, dbName, "failed to create clients")
 	runSample(t, write, dbName, "failed to insert data")
+	runSample(t, applyAtLeastOnce, dbName, "failed to apply mutations at least once")
 	out = runSample(t, batchWrite, dbName, "failed to write data using BatchWrite")
 	assertNotContains(t, out, "could not be applied with error")
 	runSampleWithContext(ctx, t, addNewColumn, dbName, "failed to add new column")
diff --git a/spanner/spanner_snippets/spanner/spanner_apply_at_least_once.go b/spanner/spanner_snippets/spanner/spanner_apply_at_least_once.go
new file mode 100644
index 0000000000..786e5ab250
--- /dev/null
+++ b/spanner/spanner_snippets/spanner/spanner_apply_at_least_once.go
@@ -0,0 +1,53 @@
+// Copyright 2024 Google LLC
+//
+// Licensed under the Apache License, Version 2.0 (the "License");
+// you may not use this file except in compliance with the License.
+// You may obtain a copy of the License at
+//
+//     https://www.apache.org/licenses/LICENSE-2.0
+//
+// Unless required by applicable law or agreed to in writing, software
+// distributed under the License is distributed on an "AS IS" BASIS,
+// WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+// See the License for the specific language governing permissions and
+// limitations under the License.
+
+package spanner
+
+import (
+	"context"
+	"io"
+
+	"cloud.google.com/go/spanner"
+)
+
+// applyAtLeastOnce shows how to apply mutations in a single-use write transaction.
+// Single-use write transactions have no replay protection.
+func applyAtLeastOnce(w io.Writer, db string) error {
+	ctx := context.Background()
+	client, err := spanner.NewClient(ctx, db)
+	if err != nil {
+		return err
+	}
+	defer client.Close()
+
+	singerColumns := []string{"SingerId", "FirstName", "LastName"}
+	albumColumns := []string{"SingerId", "AlbumId", "AlbumTitle"}
+	m := []*spanner.Mutation{
+		spanner.InsertOrUpdate("Singers", singerColumns, []interface{}{1, "Marc", "Richards"}),
+		spanner.InsertOrUpdate("Singers", singerColumns, []interface{}{2, "Catalina", "Smith"}),
+		spanner.InsertOrUpdate("Singers", singerColumns, []interface{}{3, "Alice", "Trentor"}),
+		spanner.InsertOrUpdate("Singers", singerColumns, []interface{}{4, "Lea", "Martin"}),
+		spanner.InsertOrUpdate("Singers", singerColumns, []interface{}{5, "David", "Lomond"}),
+		spanner.InsertOrUpdate("Albums", albumColumns, []interface{}{1, 1, "Total Junk"}),
+		spanner.InsertOrUpdate("Albums", albumColumns, []interface{}{1, 2, "Go, Go, Go"}),
+		spanner.InsertOrUpdate("Albums", albumColumns, []interface{}{2, 1, "Green"}),
+		spanner.InsertOrUpdate("Albums", albumColumns, []interface{}{2, 2, "Forever Hold Your Peace"}),
+		spanner.InsertOrUpdate("Albums", albumColumns, []interface{}{2, 3, "Terrified"}),
+	}
+	// The spanner.ApplyAtLeastOnce() option instructs the client to use a single Commit request
+	// to apply the mutations, instead of first executing a BeginTransaction RPC. This reduces
+	// the number of round-trips to Spanner, but also means that there is no replay protection.
+	_, err = client.Apply(ctx, m, spanner.ApplyAtLeastOnce())
+	return err
+}