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Dear,
I'm wondering why I get no results when using a vcf obtained from DELLY 1.2.8:
-------------------------------- Overall Stats: Overall EventPrecision: NaN Overall EventRecall: 0.000% Overall EventFscore: NaN -------------------------------- QuerySample TruthSample QueryTotal QueryTp QueryFp Precision TruthTotal TruthTp TruthFn Recall Fscore BaseQueryTotal BaseQueryTp BaseQueryFp BasePrecision BaseTruthTotal BaseTruthTp BaseTruthFn BaseRecall BaseFscore HCC1395BL HCC1395 0 0 0 NaN 1283 0 1283 0.000% NaN 0 0 0 NaN 9085750 0 9085750 0.000% NaN
Clearly, it doesn't detect any SV coming from DELLY vcf. Performing a basic intersectBed, there're almost 100% coincidencies, for example:
DELLY (this is in somatic mode, control and tumor samples in format):
chr22 40889941 DUP00258531 C <DUP> 2340 PASS PRECISE;SVTYPE=DUP;SVMETHOD=EMBL.DELLYv1.2.8;END=40893271;PE=26;MAPQ=60;CT=5to3;CIPOS=-3,3;CIEND=-3,3;SRMAPQ=60;INSLEN=0;HOMLEN=2;SR=13;SRQ=1;CONSENSUS=CATAATATAATTAATATGCAAAACAGGTTGCTTTCCCAACACAGATCCTTTTTAATAGATACATCTGGCCGGGCGCTTATGCCTGTAATCCCAGCACTTTGGGAGGCCTGTACAGTCCTTTGGCCTCCTTGATCCACAGTTTTCTGCACTTCATGGTATATATCTGCTGAGTTATTAAAAATAATAATCTATCATTAATCAAGTCTAAATATT;CE=1.94155;CONSBP=107;RDRATIO=1.25412;SOMATIC GT:GL:GQ:FT:RCL:RC:RCR:RDCN:DR:DV:RR:RV 0/0:0,-12.0103,-114.269:120:PASS:286:591:303:2:57:0:40:0 0/1:-10.7214,0,-318.662:107:PASS:901:2177:829:3:159:27:124:18
TRUTH SET
chr22 40889940 chr22_40889940_chr22_40893272_-+ N <DUP> . PASS CHR2=chr22;SVTYPE=DUP;END=40893272;SVLEN=3332;REPLICATE=34;PACBIO=0;NANOPORE=1 GT 0/1 3331
Running witty.er with the same samples with MANTA and DYSGU performs perfectly well All I can detect is that DELLY doesn't output SVLEN
Many thanks Jordi
The text was updated successfully, but these errors were encountered:
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Dear,
I'm wondering why I get no results when using a vcf obtained from DELLY 1.2.8:
Clearly, it doesn't detect any SV coming from DELLY vcf. Performing a basic intersectBed, there're almost 100% coincidencies, for example:
DELLY (this is in somatic mode, control and tumor samples in format):
TRUTH SET
Running witty.er with the same samples with MANTA and DYSGU performs perfectly well
All I can detect is that DELLY doesn't output SVLEN
Many thanks
Jordi
The text was updated successfully, but these errors were encountered: