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T-PHATE algorithm #115

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apathanasiadis opened this issue Jun 6, 2022 · 0 comments
Open

T-PHATE algorithm #115

apathanasiadis opened this issue Jun 6, 2022 · 0 comments
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@apathanasiadis
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apathanasiadis commented Jun 6, 2022

Hello, I recently came across the T-PHATE algorithm you published. Regarding its implementation, I was wondering how did you interfere with the PHATE algorithm. As far as I understand, you multiply the diffusion operator $P_D$ with the normalized autocorrelative transition probability matrix $P_T$. Can I somehow input this new operator $P=P_D P_T$ for the transformation of data? I know I can get the diffusion operator, diff_op, after the fitting, but I am not sure how to input $P$ as the new diffusion operator matrix for the transformation.
Thanks for any help in advance.

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