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Explore improvements to adjustment methods #50

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smlmbrt opened this issue Aug 6, 2023 · 0 comments
Open

Explore improvements to adjustment methods #50

smlmbrt opened this issue Aug 6, 2023 · 0 comments
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enhancement New feature or request

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@smlmbrt
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smlmbrt commented Aug 6, 2023

To do:

  • Explore whether the PCA-based regression can be improved by weighting the reference samples by 1/N_popuation (to make sure that the regression will fit all ancestries equally)
  • kNN regression for the distribution of the PGS
@smlmbrt smlmbrt added the enhancement New feature or request label Aug 6, 2023
@smlmbrt smlmbrt changed the title Improve adjustment methods Explore improvements to adjustment methods Oct 3, 2023
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