From 8c3319c6374f830145a9c88dda33086b28f51f35 Mon Sep 17 00:00:00 2001 From: Xiao Chen <chenxecho@gmail.com> Date: Thu, 26 Jan 2023 10:08:43 -0800 Subject: [PATCH] update readme --- README.md | 2 ++ 1 file changed, 2 insertions(+) diff --git a/README.md b/README.md index ece4c92..233bca6 100644 --- a/README.md +++ b/README.md @@ -6,6 +6,8 @@ Chen X, Harting J, Farrow E, et al. Comprehensive SMN1 and SMN2 profiling for sp For whole-genome sequencing (WGS) data, we recommend >20X, ideally 30X, genome coverage. Low coverage or short read length could result in less accurate phasing, especially when haplotypes are highly similar to each other in Exons 1-6. For hybrid capture-based enrichment data, a higher read depth (>50X) is recommended as the read length is generally shorter than WGS. +Currently Paraphase only works on GRCh38. Support for GRCh37 will be adde in the future. + ## Contact If you need assistance or have suggestions, please don't hesitate to reach out by email or open a GitHub issue.