Snakemake rerun triggers do not check for changes in ped structure and content

[Nicolai-vKuegelgen]

Describe the bug
Sometimes sex information in the (biomedsheet) samplesheet needs to be updated or newly sequenced members are added to a family. This update should also lead to according changes in ped files and and all other relevant files.

To Reproduce
Steps to reproduce the behavior:

1. Run snappy with sex information (i.e. unknown sex that crashes gcnv)
2. Update the sex information in the samplesheet
3. Restart any snappy step that includes the WritePedigreeStepPart (i.e. sv_calling_targeted)
4. write_pedigree is not rerun

Expected behavior
A change in the input (meta)data should trigger a rerun of all affected downstream files.

Additional context

• The current input for write_pedigree seems to only include bam files.
• The rerun triggers for number/set of input files should be re-enabled to catch addition of family members
• A rerun trigger on params could be used to forward sex changes to snakemake

[Nicolai-vKuegelgen]

Additon: it seems like this extends to other changes of the ped/family structure as well. I.e. addition a new family member will not trigger a re-write of the ped file to include this update.