diff --git a/include/boost/math/tools/config.hpp b/include/boost/math/tools/config.hpp
index b3a8c2cf89..93d6af8641 100644
--- a/include/boost/math/tools/config.hpp
+++ b/include/boost/math/tools/config.hpp
@@ -465,7 +465,7 @@ struct non_type {};
 #if defined(BOOST_MATH_STANDALONE) && defined(_GLIBCXX_USE_FLOAT128) && defined(__GNUC__) && defined(__GNUC_MINOR__) && defined(__GNUC_PATCHLEVEL__) && !defined(__STRICT_ANSI__) \
    && !defined(BOOST_MATH_DISABLE_FLOAT128) && !defined(BOOST_MATH_USE_FLOAT128)
 #  define BOOST_MATH_USE_FLOAT128
-#elif defined(BOOST_HAS_FLOAT128) && !defined(BOOST_MATH_USE_FLOAT128)
+#elif defined(BOOST_HAS_FLOAT128) && !defined(BOOST_MATH_USE_FLOAT128) && !defined(BOOST_MATH_DISABLE_FLOAT128)
 #  define BOOST_MATH_USE_FLOAT128
 #endif
 #ifdef BOOST_MATH_USE_FLOAT128