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Genomic locations of exons in - strand genes #558

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thomas-cong opened this issue Aug 22, 2023 · 0 comments
Open

Genomic locations of exons in - strand genes #558

thomas-cong opened this issue Aug 22, 2023 · 0 comments

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@thomas-cong
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Currently genes that run on the negative strand (such as TP53) have their exon locations inverted relative to what is demonstrated.

image
For example, exon 4 of TP53 should start from amino acid 33 to amino acid 125, but the genomic location currently represented indicates that the exon starts from amino acid 125 to amino acid 33 due to TP53 being on the minus strand.

It should be possible to invert the genomic location in the text for all negative stranded genes while keeping the URL identical for linkout to IGV.
Example:

Original:
Screen Shot 2023-08-22 at 1 27 25 PM

Can be changed to:
Screen Shot 2023-08-22 at 1 33 17 PM
and retain the same functionality.

It may also be worth specifying which strand it is in the genomic flag as well using +/-.

@JREastonMarks JREastonMarks transferred this issue from cBioPortal/cbioportal Mar 1, 2024
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