GO:0022627 cytosolic small ribosomal subunit IBA with S000003286 , PTN000325517

[ValWood]

• PTHR ID & PTN node:

• Sequences with problematic annotation (ID + gene/protein name):

https://www.pombase.org/gene/SPBC4B4.04

• Type of Issue: Erroneous source or erroneous propagation, or other issue

is an elongation factor, not part of ribosome

problem is source annotation
https://www.yeastgenome.org/locus/S000003286
@edwong57

• Add the label 'high priority' if needed. Generally high priority issues affect a lot of proteins, and annotations are incorrect (as opposed to just imprecise).

[edwong57]

I took out the 'part of' annotation, but I kept the 'located in' annotation. That should still fix the problem, right?

[ValWood]

I'm not sure. I don't think it should be located_in ribosome if it isn't a ribosomal subunit. Maybe ribosome small subunit binding?

This is pertinent to the ontology call discussion, it's a translation factor which seems to bind the ribosome and the tRNA.
It seems to assist assists in delivering tRNA to the ribosome.

[pgaudet]

Ribosome binding would be right if the protein is not part of the ribosome.

[edwong57]

From my interpretation of the definition on this page, https://wiki.geneontology.org/Located_in, 'located in' seems appropriate. Part_of would be for members of a protein-containing complex, wouldn't it? I could add ribosome binding, but I don't want to lose the CC annotation, and 'cytosol' seems too broad.

[ValWood]

This is indeed confusing:

It also says
'Located in' is not used for relating gene products to a 'protein-containing complex'; those associations use 'part of

So I guess whether this is allowed comes back to the way the ribosome is classified (organelle or protein complex)
I thought we decided "complex" but currently it's organelle.

[pgaudet]

Right, as far as I know the final decision has not been made.