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DESCRIPTION
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Package: MADloy
Type: Package
Title: Package to detect mosaic LOY from SNP array data
Version: 1.0.7
Date: 2024-03-01
Author: Juan R Gonzalez
Maintainer: Juan R Gonzalez <[email protected]>
Depends:
data.table,
R (>= 3.2.0),
Imports:
BiocGenerics,
GenomeInfoDb,
GenomicRanges,
graphics,
IRanges,
parallel,
stats,
utils,
wordcloud
Description: This packages is a suit of functions to perform association analysis of
mosaic LOY and quantitative or continuous outcomes. It uses SNP array data in pennCNV
format (e.g. having snp_name, chromosome, position, LRR, BAF and genotype). There are
functions to perform quality control of samples, functions to process raw data and extract
the LRR and BAF information of required genomic regions, and a function to perform
calling based on Normal Inverse Gaussian distribution that properly fits LRR data.
License: GPL (>= 2)
URL: https://github.com/isglobal-brge/MADloy and http://brge.isglobal.org
VignetteBuilder: knitr
Suggests:
knitr,
rmarkdown
LazyData: FALSE
Encoding: UTF-8
RoxygenNote: 7.2.3