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<!DOCTYPE html>
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<title>2023 Datawiz Scholars</title>
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<h4 class="rvt-ts-18 rvt-text-bold">PAST SCHOLARS</h4>
<h2 class="rvt-items-center rvt-text-bold">SCHOLARS 2023</h2>
<p class="rvt-ts-20 rvt-color-black-500">The Datawiz program hosted 14 Scholars in Summer 2023.
Please find below the headshot and project summaries of 2023 Scholars.
Posters were presented by the students on July 27, 2023</p>
</div>
<div class="rvt-m-top-xxl rvt-m-top-md-md-up rvt-flow rvt-prose">
<table>
<tr>
<td>
<center><div><img src="images/scholars/2023/person.jpg" width="128" height="128" alt="aliza-image"></div>
<h4>Aliza Islam</h4>
<div style="font-size: 12px; line-height: 1em;">Indiana University Purdue University, Indianapolis</div>
</center>
</td>
<td style="width: 75%">
<div class="rvt-accordion" data-rvt-accordion="test-accordion" style="border:1px solid #ddd" >
<h3 class="rvt-accordion__summary">
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<span class="rvt-accordion__toggle-text">Project Summary</span>
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<p class="rvt-m-all-remove">Aliza's research aimed to retrieve the
PETase gene sequence from the NCBI database and obtain the upstream
region as a source of potential promoter elements using UNIPORT.
Afterward, conserved motifs were identified within the PETase gene
sequence using the MEME Suite that may serve as binding sites for
transcription factors involved in PETase regulation. </p>
</div>
</div>
</td>
</tr>
</table>
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<table>
<tr>
<td>
<center><div><img src="images/scholars/2023/anaiya.jpg" width="128" height="128" alt="anaiya-image"></div>
<h4>Anaiya Rice</h4>
<div style="font-size: 12px; line-height: 1em;">North Carolina Agricultural and Technical State University</div>
</center>
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</h3>
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<p class="rvt-m-all-remove">Anaiya's project involved a rigorous investigation into the influence of social determinants of health (SDOH) on a range of cardiovascular diseases (CVD) and related conditions, encompassing heart disease, stroke, and diabetes. Data collection and analysis revealed compelling evidence that non-medical factors do impact the rate of CVD mortality.</p>
</div>
</div>
</td>
</tr>
</table>
</div>
<div class="rvt-m-top-xxl rvt-m-top-md-md-up rvt-flow rvt-prose">
<table>
<tr>
<td style="text-align: center">
<center><div><img src="images/scholars/2023/charitie.jpg" width="128" height="128" alt="charitie-image"></div>
<h4>Charitie Martino</h4>
<div style="font-size: 12px; line-height: 1em;">University of South Florida</div>
</center>
</td>
<td style="width: 75%">
<div class="rvt-accordion" data-rvt-accordion="test-accordion" style="border:1px solid #ddd" >
<h3 class="rvt-accordion__summary">
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<span class="rvt-accordion__toggle-text">Project Summary</span>
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<p class="rvt-m-all-remove">Charitie's project included designing and conducting
a pilot study to validate if we can control cognitive engagement by regulating
cognitive load induced by visual complexity.In a subsequent study to this
one, cognitive load and visual complexity will be assessed with TBI population,
a group known to suffer from various cognitive impairments including
difficulties with attention, memory, processing speed, executive functions, and
problem-solving. </p>
</div>
</div>
</td>
</tr>
</table>
</div>
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<table>
<tr>
<td style="text-align: center">
<center><div><img src="images/scholars/2023/chelsea.jpg" width="128" height="128" alt="chelsea-image"></div>
<h4>Chelsea Kim Allanigue</h4>
<div style="font-size: 12px; line-height: 1em;">Indiana University Purdue University, Indianapolis</div>
</center>
</td>
<td style="width: 75%">
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<h3 class="rvt-accordion__summary">
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<p class="rvt-m-all-remove">Chelsea's project involved multiple regression
models in machine learning that are used to assess how various social
vulnerability factors, race, and eviction rates affect the infant mortality
rate for sudden infant death syndrome (SIDS). The dataset extracted from
Indiana Network for Patient Care (INPC) focused on the Marion County
population from March 2020 to April 2023. Consideration of these factors
were critical in determining how the community's demographics and
socioeconomic status relate to the rising infant mortality rate and the
population's overall health in the Covid-19 pandemic and post-pandemic
period. </p>
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<td style="text-align: center">
<center><div><img src="images/scholars/2023/cheyenne.jpg" width="128" height="128" alt="Cheyenne-image"></div>
<h4>Cheyenne Lawrence</h4>
<div style="font-size: 12px; line-height: 1em;">Augustana College</div>
</center>
</td>
<td style="width: 75%">
<div class="rvt-accordion" data-rvt-accordion="test-accordion" style="border:1px solid #ddd" >
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</div>
</button>
</h3>
<div class="rvt-accordion__panel" aria-labelledby="test-accordion-1-label" data-rvt-accordion-panel="test-accordion-1">
<p class="rvt-m-all-remove">Cheyenne's project involved RNA
modification databases and how they have been identified and
categorized. Using 15 databases that have already been
established, an overview of the species and biotypes within
them was given, along with who can access the databases and
how current each database is as of 2023. </p>
</div>
</div>
</td>
</tr>
</table>
</div>
<div class="rvt-m-top-xxl rvt-m-top-md-md-up rvt-flow rvt-prose">
<table>
<tr>
<td style="text-align: center">
<center><div><img src="images/scholars/2023/chitra.jpg" width="128" height="128" alt="Chitra-image"></div>
<h4>Chitra Sunil</h4>
<div style="font-size: 12px; line-height: 1em;">University of Cincinnati College of Medicine</div>
</center>
</td>
<td style="width: 75%">
<div class="rvt-accordion" data-rvt-accordion="test-accordion" style="border:1px solid #ddd" >
<h3 class="rvt-accordion__summary">
<button class="rvt-accordion__toggle" data-rvt-accordion-trigger="test-accordion-1">
<span class="rvt-accordion__toggle-text">Project Summary</span>
<div class="rvt-accordion__toggle-icon">
<svg xmlns="http://www.w3.org/2000/svg" width="16" height="16"viewBox="0 0 16 16">
<g fill="currentColor">
<path class="rvt-accordion__icon-bar" d="M8,15a1,1,0,0,1-1-1V2A1,1,0,0,1,9,2V14A1,1,0,0,1,8,15Z" />
<path d="M14,9H2A1,1,0,0,1,2,7H14a1,1,0,0,1,0,2Z" />
</g>
</svg>
</div>
</button>
</h3>
<div class="rvt-accordion__panel" aria-labelledby="test-accordion-1-label" data-rvt-accordion-panel="test-accordion-1">
<p class="rvt-m-all-remove">Chitra's project focused on drug repurposing for Alzheimer's
Disease. As part of this process,she studied the spatio-topological signature of
trichostatin-a in mouse and human brains to identify which regions would be
most affected by treatment. These results are beneficial as we now know that
trichostatin-a is a potential drug that can be used to treat Alzheimer's.
This method is very time and cost-efficient and helps make significant advancements
in finding a treatment method for Alzheimer's. </p>
</div>
</div>
</td>
</tr>
</table>
</div>
<div class="rvt-m-top-xxl rvt-m-top-md-md-up rvt-flow rvt-prose">
<table>
<tr>
<td style="text-align: center">
<center><div><img src="images/scholars/2023/person.jpg" width="128" height="128" alt="David-image"></div>
<h4>David Medina</h4>
<div style="font-size: 12px; line-height: 1em;">Universidad Ana G. Mendez</div>
</center>
</td>
<td style="width: 75%">
<div class="rvt-accordion" data-rvt-accordion="test-accordion" style="border:1px solid #ddd" >
<h3 class="rvt-accordion__summary">
<button class="rvt-accordion__toggle" data-rvt-accordion-trigger="test-accordion-1">
<span class="rvt-accordion__toggle-text">Project Summary</span>
<div class="rvt-accordion__toggle-icon">
<svg xmlns="http://www.w3.org/2000/svg" width="16" height="16"viewBox="0 0 16 16">
<g fill="currentColor">
<path class="rvt-accordion__icon-bar" d="M8,15a1,1,0,0,1-1-1V2A1,1,0,0,1,9,2V14A1,1,0,0,1,8,15Z" />
<path d="M14,9H2A1,1,0,0,1,2,7H14a1,1,0,0,1,0,2Z" />
</g>
</svg>
</div>
</button>
</h3>
<div class="rvt-accordion__panel" aria-labelledby="test-accordion-1-label" data-rvt-accordion-panel="test-accordion-1">
<p class="rvt-m-all-remove">David's project under Dr. Janga and other mentors
involved investigating programmable RNA editing using RNA-targeting
CRISPR Cas13 knockdown, a potent tool for precise RNA information
manipulation in research and disease treatment. These findings pave
the way for future research utilizing RNA-targeting CRISPR Cas13
knockdown in diverse scientific and therapeutic application. </p>
</div>
</div>
</td>
</tr>
</table>
</div>
<div class="rvt-m-top-xxl rvt-m-top-md-md-up rvt-flow rvt-prose">
<table>
<tr>
<td style="text-align: center">
<center><div><img src="images/scholars/2023/person.jpg" width="128" height="128" alt="Kalynn-image"></div>
<h4>Kalynn Jones</h4>
<div style="font-size: 12px; line-height: 1em;">Xavier Univeristy Of Louisiana</div>
</center>
</td>
<td style="width: 75%">
<div class="rvt-accordion" data-rvt-accordion="test-accordion" style="border:1px solid #ddd" >
<h3 class="rvt-accordion__summary">
<button class="rvt-accordion__toggle" data-rvt-accordion-trigger="test-accordion-1">
<span class="rvt-accordion__toggle-text">Project Summary</span>
<div class="rvt-accordion__toggle-icon">
<svg xmlns="http://www.w3.org/2000/svg" width="16" height="16"viewBox="0 0 16 16">
<g fill="currentColor">
<path class="rvt-accordion__icon-bar" d="M8,15a1,1,0,0,1-1-1V2A1,1,0,0,1,9,2V14A1,1,0,0,1,8,15Z" />
<path d="M14,9H2A1,1,0,0,1,2,7H14a1,1,0,0,1,0,2Z" />
</g>
</svg>
</div>
</button>
</h3>
<div class="rvt-accordion__panel" aria-labelledby="test-accordion-1-label" data-rvt-accordion-panel="test-accordion-1">
<p class="rvt-m-all-remove">Kalynn's project was about delirium.
Delirium is a serious cognitive disorder that, although common in
ICU patients, is inadequately understood. Further comprehension can
be obtained via analyzing biomarkers and their values relevant to
delirium patients in comparison to healthy subjects. By researching
delirium-specific biomarkers in reference to the muscle and brain
biomarkers, it was aimed to unveil a connection that makes it easier
to diagnose and treat patients with delirium in an ICU setting. </p>
</div>
</div>
</td>
</tr>
</table>
</div>
<div class="rvt-m-top-xxl rvt-m-top-md-md-up rvt-flow rvt-prose">
<table>
<tr>
<td style="text-align: center">
<center><div><img src="images/scholars/2023/kelly.jpg" width="128" height="128" alt="Kelly-image"></div>
<h4>Kelly Shin</h4>
<div style="font-size: 12px; line-height: 1em;">Purdue University</div>
</center>
</td>
<td style="width: 75%">
<div class="rvt-accordion" data-rvt-accordion="test-accordion" style="border:1px solid #ddd" >
<h3 class="rvt-accordion__summary">
<button class="rvt-accordion__toggle" data-rvt-accordion-trigger="test-accordion-1">
<span class="rvt-accordion__toggle-text">Project Summary</span>
<div class="rvt-accordion__toggle-icon">
<svg xmlns="http://www.w3.org/2000/svg" width="16" height="16"viewBox="0 0 16 16">
<g fill="currentColor">
<path class="rvt-accordion__icon-bar" d="M8,15a1,1,0,0,1-1-1V2A1,1,0,0,1,9,2V14A1,1,0,0,1,8,15Z" />
<path d="M14,9H2A1,1,0,0,1,2,7H14a1,1,0,0,1,0,2Z" />
</g>
</svg>
</div>
</button>
</h3>
<div class="rvt-accordion__panel" aria-labelledby="test-accordion-1-label" data-rvt-accordion-panel="test-accordion-1">
<p class="rvt-m-all-remove">Kelly's project involved the use of machine learning
approaches and MRI scans to estimate brain ages by calculating the difference between
predicted brain age and chronological brain age also known as Delta to
determine if there is association between accelerated BrainAGE and cognitive
decline. </p>
</div>
</div>
</td>
</tr>
</table>
</div>
<div class="rvt-m-top-xxl rvt-m-top-md-md-up rvt-flow rvt-prose">
<table>
<tr>
<td style="text-align: center">
<center><div><img src="images/scholars/2023/melina.jpg" width="128" height="128" alt="Melina-image"></div>
<h4>Melina Palakal</h4>
<div style="font-size: 12px; line-height: 1em;">Indiana University, Bloomington</div>
</center>
</td>
<td style="width: 75%">
<div class="rvt-accordion" data-rvt-accordion="test-accordion" style="border:1px solid #ddd" >
<h3 class="rvt-accordion__summary">
<button class="rvt-accordion__toggle" data-rvt-accordion-trigger="test-accordion-1">
<span class="rvt-accordion__toggle-text">Project Summary</span>
<div class="rvt-accordion__toggle-icon">
<svg xmlns="http://www.w3.org/2000/svg" width="16" height="16"viewBox="0 0 16 16">
<g fill="currentColor">
<path class="rvt-accordion__icon-bar" d="M8,15a1,1,0,0,1-1-1V2A1,1,0,0,1,9,2V14A1,1,0,0,1,8,15Z" />
<path d="M14,9H2A1,1,0,0,1,2,7H14a1,1,0,0,1,0,2Z" />
</g>
</svg>
</div>
</button>
</h3>
<div class="rvt-accordion__panel" aria-labelledby="test-accordion-1-label" data-rvt-accordion-panel="test-accordion-1">
<p class="rvt-m-all-remove">Melina's project involved the use of ad-hoc low-order
enumerations and clustering-based enclosed graph strategies from past cancer
studies to investigate the CNs in kidney spatial proteomics associated with
chronic kidney disease (CKD) and acute kidney infection (AKI). These
investigations will then allowed to analyze the differences in spatial organizations
between CKD and AKI. In the time duration of this program, Melina along with her
mentors was able to develop a methodology to produce a binary mask of the segmented
cells within the tissue image, as well as the necessary coordinates that
will be used to analyze the spatial organization of the tissue sample through the
use of an image processing software. </p>
</div>
</div>
</td>
</tr>
</table>
</div>
<div class="rvt-m-top-xxl rvt-m-top-md-md-up rvt-flow rvt-prose">
<table>
<tr>
<td style="text-align: center">
<center><div><img src="images/scholars/2023/nhan.jpg" width="128" height="128" alt="Nhan-image"></div>
<h4>Nhan Nguyen</h4>
<div style="font-size: 12px; line-height: 1em;">Texas A and M University</div>
</center>
</td>
<td style="width: 75%">
<div class="rvt-accordion" data-rvt-accordion="test-accordion" style="border:1px solid #ddd" >
<h3 class="rvt-accordion__summary">
<button class="rvt-accordion__toggle" data-rvt-accordion-trigger="test-accordion-1">
<span class="rvt-accordion__toggle-text">Project Summary</span>
<div class="rvt-accordion__toggle-icon">
<svg xmlns="http://www.w3.org/2000/svg" width="16" height="16"viewBox="0 0 16 16">
<g fill="currentColor">
<path class="rvt-accordion__icon-bar" d="M8,15a1,1,0,0,1-1-1V2A1,1,0,0,1,9,2V14A1,1,0,0,1,8,15Z" />
<path d="M14,9H2A1,1,0,0,1,2,7H14a1,1,0,0,1,0,2Z" />
</g>
</svg>
</div>
</button>
</h3>
<div class="rvt-accordion__panel" aria-labelledby="test-accordion-1-label" data-rvt-accordion-panel="test-accordion-1">
<p class="rvt-m-all-remove">Nhan's project involved Identification of patients with
PCC and evaluation by applying machine learning tools to Electronic Health
Record (EHR) data. A rules-based phenotype that is based on symptoms or
conditions after the acute infection phase of COVID will be used as a reference
for identification of PCC-positive patients. Then, XGBoost was used
with all features present within the EHR data that are not already used
by the phenotype. Results were examined, and feature selection was
applied. Features will be studied to evaluate the potential impact. </p>
</div>
</div>
</td>
</tr>
</table>
</div>
<div class="rvt-m-top-xxl rvt-m-top-md-md-up rvt-flow rvt-prose">
<table>
<tr>
<td style="text-align: center">
<center><div><img src="images/scholars/2023/rachel.jpg" width="128" height="128" alt="Rachel-image"></div>
<h4>Rachel Mack</h4>
<div style="font-size: 12px; line-height: 1em;">John Hopkins University</div>
</center>
</td>
<td style="width: 75%">
<div class="rvt-accordion" data-rvt-accordion="test-accordion" style="border:1px solid #ddd" >
<h3 class="rvt-accordion__summary">
<button class="rvt-accordion__toggle" data-rvt-accordion-trigger="test-accordion-1">
<span class="rvt-accordion__toggle-text">Project Summary</span>
<div class="rvt-accordion__toggle-icon">
<svg xmlns="http://www.w3.org/2000/svg" width="16" height="16"viewBox="0 0 16 16">
<g fill="currentColor">
<path class="rvt-accordion__icon-bar" d="M8,15a1,1,0,0,1-1-1V2A1,1,0,0,1,9,2V14A1,1,0,0,1,8,15Z" />
<path d="M14,9H2A1,1,0,0,1,2,7H14a1,1,0,0,1,0,2Z" />
</g>
</svg>
</div>
</button>
</h3>
<div class="rvt-accordion__panel" aria-labelledby="test-accordion-1-label" data-rvt-accordion-panel="test-accordion-1">
<p class="rvt-m-all-remove">Rachel's project was about
comparing the EK228 knockout strain to the N2
wildtype strain of C.elegans because the EK228
strain of C.elegans may be vital to studying the
early embryonic effects of DYRK1A in mammalian
development, and characterization of this strain may
provide insight into the roles of DYRK1A in
individuals with Down syndrome. </p>
</div>
</div>
</td>
</tr>
</table>
</div>
<div class="rvt-m-top-xxl rvt-m-top-md-md-up rvt-flow rvt-prose">
<table>
<tr>
<td style="text-align: center">
<center><div><img src="images/scholars/2023/simranjit.jpg" width="128" height="128" alt="Simranjit-image"></div>
<h4>Simranjit Virk</h4>
<div style="font-size: 12px; line-height: 1em;">Indiana University Purdue University, Indianapolis</div>
</center>
</td>
<td style="width: 75%">
<div class="rvt-accordion" data-rvt-accordion="test-accordion" style="border:1px solid #ddd" >
<h3 class="rvt-accordion__summary">
<button class="rvt-accordion__toggle" data-rvt-accordion-trigger="test-accordion-1">
<span class="rvt-accordion__toggle-text">Project Summary</span>
<div class="rvt-accordion__toggle-icon">
<svg xmlns="http://www.w3.org/2000/svg" width="16" height="16"viewBox="0 0 16 16">
<g fill="currentColor">
<path class="rvt-accordion__icon-bar" d="M8,15a1,1,0,0,1-1-1V2A1,1,0,0,1,9,2V14A1,1,0,0,1,8,15Z" />
<path d="M14,9H2A1,1,0,0,1,2,7H14a1,1,0,0,1,0,2Z" />
</g>
</svg>
</div>
</button>
</h3>
<div class="rvt-accordion__panel" aria-labelledby="test-accordion-1-label" data-rvt-accordion-panel="test-accordion-1">
<p class="rvt-m-all-remove">Simranjit's project involved an extensive study examining the roles of Matrix Metalloproteinases (MMPs) in various health conditions. By leveraging innovative methodologies including Genome-Wide Association Studies (GWAS), eQTL analysis, and Mendelian Randomization (MR), they discovered novel associations between MMPs and these diseases. The findings were robustly validated using the independent "All of Us" Research Workbench data. These results provide new insights into disease development and progression, potentially guiding personalized treatment strategies. Despite certain limitations, the work represents a significant step forward in understanding MMPs' implications in human health. </p>
</div>
</div>
</td>
</tr>
</table>
</div>
<div class="rvt-m-top-xxl rvt-m-top-md-md-up rvt-flow rvt-prose">
<table>
<tr>
<td style="text-align: center">
<center><div><img src="images/scholars/2023/person.jpg" width="128" height="128" alt="Zaidon-image"></div>
<h4>Zaidon Cange</h4>
<div style="font-size: 12px; line-height: 1em;">Barry University</div>
</center>
</td>
<td style="width: 75%">
<div class="rvt-accordion" data-rvt-accordion="test-accordion" style="border:1px solid #ddd" >
<h3 class="rvt-accordion__summary">
<button class="rvt-accordion__toggle" data-rvt-accordion-trigger="test-accordion-1">
<span class="rvt-accordion__toggle-text">Project Summary</span>
<div class="rvt-accordion__toggle-icon">
<svg xmlns="http://www.w3.org/2000/svg" width="16" height="16"viewBox="0 0 16 16">
<g fill="currentColor">
<path class="rvt-accordion__icon-bar" d="M8,15a1,1,0,0,1-1-1V2A1,1,0,0,1,9,2V14A1,1,0,0,1,8,15Z" />
<path d="M14,9H2A1,1,0,0,1,2,7H14a1,1,0,0,1,0,2Z" />
</g>
</svg>
</div>
</button>
</h3>
<div class="rvt-accordion__panel" aria-labelledby="test-accordion-1-label" data-rvt-accordion-panel="test-accordion-1">
<p class="rvt-m-all-remove">Zaidon's project involved RNA modification
datatbase and how they have been identified and categorized.
Using 15 databases that have already been established,
an overview of the species and biotypes within them was given,
along with who can access the databases and how
current each database is as of 2023. </p>
</div>
</div>
</td>
</tr>
</table>
</div>
</div>
</section>
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