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I would like to see the DGE calculations separated from the egsea analysis. It would be most convenient and flexible to simply supply a list of topTable dataframes as input for the enrichment analysis. For example, we often use the duplicateCorrelation method to account for repeated measures on subjects within a design. Unless I've missed it, the duplicateCorrelation method is not supported in the limma voom workflow within the current egsea function. Perhaps more importantly, a list of topTable DF as input would allow me to analyze and compare contrasts from different experiments.
Best Regards,
John Thompson, Ph.D.
Research Fellow
Translational Bioinformatics
Bristol-Myers Squibb
The text was updated successfully, but these errors were encountered:
I would like to see the DGE calculations separated from the egsea analysis. It would be most convenient and flexible to simply supply a list of topTable dataframes as input for the enrichment analysis. For example, we often use the duplicateCorrelation method to account for repeated measures on subjects within a design. Unless I've missed it, the duplicateCorrelation method is not supported in the limma voom workflow within the current egsea function. Perhaps more importantly, a list of topTable DF as input would allow me to analyze and compare contrasts from different experiments.
Best Regards,
John Thompson, Ph.D.
Research Fellow
Translational Bioinformatics
Bristol-Myers Squibb
The text was updated successfully, but these errors were encountered: