- Improve error handling if all genes give errors
- Add option for likelihood ratio test (LRT) in
glmmSeq()
andlmmSeq()
- Enable changing of model formula, family and control parameters when refitting
model for a single gene in
glmmRefit()
- Fix passing of
...
in parallelisation on windows inglmmSeq()
&lmmSeq()
- Add option to
glmmSeq()
to useglmmTMB
package for fitting negative binomial GLMM (or other GLM family) models - Add
plab
argument tomodelPlots
to customise p-value labels - Add mean expression column
meanExp
to results in@stats$res
slot
- Further speed enhancements to
lmmSeq()
usinglme4::modular
code. Speed increase of around 25%.
- Significant update including output of standard error on fitted coefficients
for both
glmmSeq
andlmmSeq
- Add
summary
function for glmmSeq and lmmSeq to display results for an individual gene - Reorganised
@stats
slot in output objects to include more information including DF - Added option of using Saiterthwaite's DF method with ANOVA type III tables as
option for
lmmSeq
using thelmerTest
package - Added
lmmRefit
function to fit an identical (g)lmer model. This can then be passed to theemmeans
package for visualisation of more complex models. - Separated
modelPlots
(base graphics) andggmodelPlots
(ggplot2) - Streamlined
modelPlots
to allow for simplest casegene ~ Time + (1 | ID)
- Fast version of
lmmSeq()
. Improves speed of calculation of type 2 Wald test. Overall speed increase of 25-50%. - Faster version of
glmmSeq()
- Automatically detects
id
column name from the RE term in the formula
- Add
...
option tofcPlot
which is passed toplotly()
orggplot()
- set
annotationPosition=FALSE
infcPlot
so arrows/connectors are not moved
- Add lmmSeq function for gaussian linear mixed models
- Fix CMD check errors
- Fix colours in pairedPlots and modelPlots
- Add progress bars to glmmSeq functions
- Add option
returnList
to return glmmSeq output as list (to make error catching easier)
- Fix missing plots in vignette
- This is the initial build of
glmmSeq