diff --git a/nf-research-tools.jsonld b/nf-research-tools.jsonld index 4bb6d37..23c0440 100644 --- a/nf-research-tools.jsonld +++ b/nf-research-tools.jsonld @@ -8,2083 +8,569 @@ }, "@graph": [ { - "@id": "schema:Text", - "@type": [ - "schema:DataType", - "rdfs:Class" - ], - "rdfs:comment": "Data type: Text.", - "rdfs:label": "Text" - }, - { - "@id": "schema:Number", - "@type": [ - "schema:DataType", - "rdfs:Class" - ], - "rdfs:comment": "Data type: Number.", - "rdfs:label": "Number" - }, - { - "@id": "schema:Integer", - "@type": "rdfs:Class", - "rdfs:comment": "Data type: Integer.", - "rdfs:label": "Integer", - "rdfs:subClassOf": { - "@id": "schema:Number" - } - }, - { - "@id": "schema:Thing", - "@type": "rdfs:Class", - "rdfs:comment": "Thing", - "rdfs:label": "Thing", - "schema:isPartOf": { - "@id": "http://schema.org" - } - }, - { - "@id": "bts:BiologicalEntity", - "@type": "rdfs:Class", - "rdfs:comment": null, - "rdfs:label": "BiologicalEntity", - "rdfs:subClassOf": { - "@id": "schema:Thing" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - } - }, - { - "@id": "bts:OntologyClass", - "@type": "rdfs:Class", - "rdfs:comment": "a concept or class in an ontology, vocabulary or thesaurus", - "rdfs:label": "OntologyClass", - "rdfs:subClassOf": { - "@id": "schema:Thing" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - } - }, - { - "@id": "bts:RelationshipType", - "@type": "rdfs:Class", - "rdfs:comment": "An OWL property used as an edge label", - "rdfs:label": "RelationshipType", - "rdfs:subClassOf": { - "@id": "bts:OntologyClass" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - } - }, - { - "@id": "bts:GeneOntologyClass", - "@type": "rdfs:Class", - "rdfs:comment": "an ontology class that describes a functional aspect of a gene, gene prodoct or complex", - "rdfs:label": "GeneOntologyClass", - "rdfs:subClassOf": { - "@id": "bts:OntologyClass" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - } - }, - { - "@id": "bts:OrganismTaxon", - "@type": "rdfs:Class", - "rdfs:comment": null, - "rdfs:label": "OrganismTaxon", - "rdfs:subClassOf": { - "@id": "bts:OntologyClass" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - } - }, - { - "@id": "bts:OrganismalEntity", - "@type": "rdfs:Class", - "rdfs:comment": "A named entity that is either a part of an organism, a whole organism, population or clade of organisms, excluding molecular entities", - "rdfs:label": "OrganismalEntity", - "rdfs:subClassOf": { - "@id": "bts:BiologicalEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - } - }, - { - "@id": "bts:IndividualOrganism", - "@type": "rdfs:Class", - "rdfs:comment": null, - "rdfs:label": "IndividualOrganism", - "rdfs:subClassOf": { - "@id": "bts:OrganismalEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - } - }, - { - "@id": "bts:Case", - "@type": "rdfs:Class", - "rdfs:comment": "An individual organism that has a patient role in some clinical context.", - "rdfs:label": "Case", - "rdfs:subClassOf": { - "@id": "bts:IndividualOrganism" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - } - }, - { - "@id": "bts:PopulationOfIndividualOrganisms", - "@type": "rdfs:Class", - "rdfs:comment": null, - "rdfs:label": "PopulationOfIndividualOrganisms", - "rdfs:subClassOf": { - "@id": "bts:OrganismalEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - } - }, - { - "@id": "bts:Biosample", - "@type": "rdfs:Class", - "rdfs:comment": null, - "rdfs:label": "Biosample", - "rdfs:subClassOf": { - "@id": "bts:OrganismalEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - } - }, - { - "@id": "bts:DiseaseOrPhenotypicFeature", - "@type": "rdfs:Class", - "rdfs:comment": "Either one of a disease or an individual phenotypic feature. 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"@type": "rdfs:Class", - "rdfs:comment": "One or more causally connected executions of molecular functions", - "rdfs:label": "BiologicalProcess", - "rdfs:subClassOf": { - "@id": "bts:BiologicalProcessOrActivity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - } - }, - { - "@id": "bts:Pathway", - "@type": "rdfs:Class", - "rdfs:comment": null, - "rdfs:label": "Pathway", - "rdfs:subClassOf": { - "@id": "bts:BiologicalProcess" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - } - }, - { - "@id": "bts:PhysiologicalProcess", - "@type": "rdfs:Class", - "rdfs:comment": null, - "rdfs:label": "PhysiologicalProcess", - "rdfs:subClassOf": { - "@id": "bts:BiologicalProcess" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - } - }, - { - "@id": "bts:CellularComponent", - "@type": "rdfs:Class", - "rdfs:comment": "A location in or around a cell", - "rdfs:label": "CellularComponent", - "rdfs:subClassOf": { - "@id": "bts:AnatomicalEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - } - }, - { - "@id": "bts:Cell", - "@type": "rdfs:Class", - "rdfs:comment": null, - "rdfs:label": "Cell", - "rdfs:subClassOf": { - "@id": "bts:AnatomicalEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - } - }, - { - "@id": "bts:CellLine", - "@type": "rdfs:Class", - "rdfs:comment": "A cell culture selected for uniformity from a cell population derived from a usually homogeneous tissue source (such as an organ).", - "rdfs:label": "CellLine", - "rdfs:subClassOf": [ - { - "@id": "bts:CellLine" - } - ], - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "sms:displayName": "cellLine", - "sms:required": "sms:false", - "sms:requiresComponent": [ - { - "@id": "bts:Donor" - } - ], - "sms:requiresDependency": [ - { - "@id": "bts:Component" - }, - { - "@id": "bts:cellLineId" - }, - { - "@id": "bts:donorId" - }, - { - "@id": "bts:organ" - }, - { - "@id": "bts:tissue" - }, - { - "@id": "bts:cellLineCategory" - }, - { - "@id": "bts:originYear" - }, - { - "@id": "bts:strProfile" - }, - { - "@id": "bts:populationDoublingTime" - }, - { - "@id": "bts:resistance" - }, - { - "@id": "bts:contaminatedMisidentified" - }, - { - "@id": "bts:cellLineGeneticDisorder" - }, - { - "@id": "bts:cellLineManifestation" - } - ], - "sms:validationRules": [] - }, - { - "@id": "bts:GrossAnatomicalStructure", - "@type": "rdfs:Class", - "rdfs:comment": null, - "rdfs:label": "GrossAnatomicalStructure", - "rdfs:subClassOf": { - "@id": "bts:AnatomicalEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - } - }, - { - "@id": "bts:ensembl", - "@type": "rdf:Property", - "rdfs:comment": "Ensembl ID for gene, protein or transcript", - "rdfs:label": "ensembl", - "schema:domainIncludes": [ - { - "@id": "bts:Transcript" - } - ], - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "schema:Text" - } - }, - { - "@id": "bts:hgnc", - "@type": "rdf:Property", - "rdfs:comment": "HGNC ID for gene", - "rdfs:label": "hgnc", - "schema:domainIncludes": { - "@id": "bts:Gene" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "schema:Integer" - } - }, - { - "@id": "bts:entrez", - "@type": "rdf:Property", - "rdfs:comment": "Entrez ID for gene", - "rdfs:label": "entrez", - "schema:domainIncludes": { - "@id": "bts:Gene" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "schema:Integer" - } - }, - { - "@id": "bts:refseq", - "@type": "rdf:Property", - "rdfs:comment": "Refseq ID for gene, protein or transcript", - "rdfs:label": "refseq", - "schema:domainIncludes": [ - { - "@id": "bts:Transcript" - } - ], - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "schema:Text" - } - }, - { - "@id": "bts:omim", - "@type": "rdf:Property", - "rdfs:comment": "Refseq ID for gene, protein or transcript", - "rdfs:label": "omim", - "schema:domainIncludes": [ - { - "@id": "bts:Disease" - } - ], - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "schema:Integer" - } - }, - { - "@id": "bts:umls", - "@type": "rdf:Property", - "rdfs:comment": "Refseq ID for gene, protein or transcript", - "rdfs:label": "umls", - "schema:domainIncludes": { - "@id": "bts:Disease" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "schema:Text" - } - }, - { - "@id": "bts:homologousTo", - "@type": "rdf:Property", - "rdfs:comment": "Shared ancestry between protein or gene", - "rdfs:label": "homologousTo", - "schema:domainIncludes": { - "@id": "bts:GeneOrGeneProduct" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:GeneOrGeneProduct" - } - }, - { - "@id": "bts:molecularlyInteractsWith", - "@type": "rdf:Property", - "rdfs:comment": null, - "rdfs:label": "molecularlyInteractsWith", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:geneticallyInteractsWith", - "@type": "rdf:Property", - "rdfs:comment": "holds between two genes whose phenotypic effects are dependent on each other in some way - such that their combined phenotypic effects are the result of some interaction between the activity of their gene products. 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"@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:decreasesAbundanceOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one decreases the amount of the other within a system of interest", - "rdfs:label": "decreasesAbundanceOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:affectsActivityOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one changes the activity of the other within a system of interest", - "rdfs:label": "affectsActivityOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:increasesActivityOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one increases the activity of the other within a system of interest", - "rdfs:label": "increasesActivityOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:decreasesActivityOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one decreases the activity of the other within a system of interest", - "rdfs:label": "decreasesActivityOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:affectsExpressionOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one changes the level of expression of the other within a system of interest", - "rdfs:label": "affectsExpressionOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:GenomicEntity" - } - }, - { - "@id": "bts:increasesExpressionOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one increases the level of expression of the other within a system of interest", - "rdfs:label": "increasesExpressionOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:GenomicEntity" - } - }, - { - "@id": "bts:decreasesExpressionOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one decreases the level of expression of the other within a system of interest", - "rdfs:label": "decreasesExpressionOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:GenomicEntity" - } - }, - { - "@id": "bts:affectsFoldingOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one changes the rate or quality of folding of the other ", - "rdfs:label": "affectsFoldingOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:increasesFoldingOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one increases the rate or quality of folding of the other ", - "rdfs:label": "increasesFoldingOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:decreasesFoldingOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one decreases the rate or quality of folding of the other ", - "rdfs:label": "decreasesFoldingOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:affectsLocalizationOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one changes the localization of the other within a system of interest", - "rdfs:label": "affectsLocalizationOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:increasesLocalizationOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one increases the proper localization of the other within a system of interest", - "rdfs:label": "increasesLocalizationOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:decreasesLocalizationOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one decreases the proper localization of the other within a system of interest", - "rdfs:label": "decreasesLocalizationOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:affectsMetabolicProcessingOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one impacts the metabolic processing of the other within a system of interest", - "rdfs:label": "affectsMetabolicProcessingOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:increasesMetabolicProcessingOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one increases the rate of metabolic processing of the other within a system of interest", - "rdfs:label": "increasesMetabolicProcessingOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:decreasesMetabolicProcessingOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one decreases the rate of metabolic processing of the other within a system of interest", - "rdfs:label": "decreasesMetabolicProcessingOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:affectsMolecularModificationOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one leads changes in the molecular modification(s) of the other (e.g. via post-translational modifications of proteins such as the addition of phosphoryl group, or via redox reaction that adds or subtracts electrons)", - "rdfs:label": "affectsMolecularModificationOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:increasesMolecularModificationOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one leads to increased molecular modification(s) of the other (e.g. via post-translational modifications of proteins such as the addition of phosphoryl group, or via redox reaction that adds or subtracts electrons)", - "rdfs:label": "increasesMolecularModificationOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:decreasesMolecularModificationOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one leads to decreased molecular modification(s) of the other (e.g. via post-translational modifications of proteins such as the addition of phosphoryl group, or via redox reaction that adds or subtracts electrons)", - "rdfs:label": "decreasesMolecularModificationOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:affectsSynthesisOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one impacts the rate of chemical synthesis of the other", - "rdfs:label": "affectsSynthesisOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:increasesSynthesisOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one increases the rate of chemical synthesis of the other", - "rdfs:label": "increasesSynthesisOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:decreasesSynthesisOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one decreases the rate of chemical synthesis of the other", - "rdfs:label": "decreasesSynthesisOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:affectsDegradationOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one impacts the rate of degradation of the other within a system of interest", - "rdfs:label": "affectsDegradationOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:increasesDegradationOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one increases the rate of degradation of the other within a system of interest", - "rdfs:label": "increasesDegradationOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:decreasesDegradationOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one decreases the rate of degradation of the other within a system of interest", - "rdfs:label": "decreasesDegradationOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:affectsMutationRateOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between a molecular entity and a genomic entity where the action or effect of the molecular entity impacts the rate of mutation of the genomic entity within a system of interest", - "rdfs:label": "affectsMutationRateOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:GenomicEntity" - } - }, - { - "@id": "bts:increasesMutationRateOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between a molecular entity and a genomic entity where the action or effect of the molecular entity increases the rate of mutation of the genomic entity within a system of interest", - "rdfs:label": "increasesMutationRateOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:GenomicEntity" - } - }, - { - "@id": "bts:decreasesMutationRateOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between a molecular entity and a genomic entity where the action or effect of the molecular entity decreases the rate of mutation of the genomic entity within a system of interest", - "rdfs:label": "decreasesMutationRateOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:GenomicEntity" - } - }, - { - "@id": "bts:affectsResponseTo", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one impacts the susceptibility of a biological entity or system (e.g. an organism, cell, cellular component, macromolecular machine, biological or pathological process) to the other", - "rdfs:label": "affectsResponseTo", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:increasesResponseTo", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one increases the susceptibility of a biological entity or system (e.g. an organism, cell, cellular component, macromolecular machine, biological or pathological process) to the other", - "rdfs:label": "increasesResponseTo", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:decreasesResponseTo", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one decreases the susceptibility of a biological entity or system (e.g. an organism, cell, cellular component, macromolecular machine, biological or pathological process) to the other", - "rdfs:label": "decreasesResponseTo", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:affectsSplicingOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between a molecular entity and an mRNA where the action or effect of the molecular entity impacts the splicing of the mRNA", - "rdfs:label": "affectsSplicingOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:Transcript" - } - }, - { - "@id": "bts:increasesSplicingOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between a molecular entity and an mRNA where the action or effect of the molecular entity increases the proper splicing of the mRNA", - "rdfs:label": "increasesSplicingOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:Transcript" - } - }, - { - "@id": "bts:decreasesSplicingOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between a molecular entity and an mRNA where the action or effect of the molecular entity decreases the proper splicing of the mRNA", - "rdfs:label": "decreasesSplicingOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:Transcript" - } - }, - { - "@id": "bts:affectsStabilityOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one impacts the stability of the other within a system of interest", - "rdfs:label": "affectsStabilityOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:increasesStabilityOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one increases the stability of the other within a system of interest", - "rdfs:label": "increasesStabilityOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:decreasesStabilityOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one decreases the stability of the other within a system of interest", - "rdfs:label": "decreasesStabilityOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:affectsTransportOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one impacts the rate of transport of the other across some boundary in a system of interest", - "rdfs:label": "affectsTransportOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:increasesTransportOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one increases the rate of transport of the other across some boundary in a system of interest", - "rdfs:label": "increasesTransportOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:decreasesTransportOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one decreases the rate of transport of the other across some boundary in a system of interest", - "rdfs:label": "decreasesTransportOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:affectsSecretionOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one impacts the rate of secretion of the other out of a cell, gland, or organ", - "rdfs:label": "affectsSecretionOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:increasesSecretionOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one increases the rate of secretion of the other out of a cell, gland, or organ", - "rdfs:label": "increasesSecretionOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:decreasesSecretionOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one decreases the rate of secretion of the other out of a cell, gland, or organ", - "rdfs:label": "decreasesSecretionOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:affectsUptakeOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one impacts the rate of uptake of the other into of a cell, gland, or organ", - "rdfs:label": "affectsUptakeOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:increasesUptakeOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one increases the rate of uptake of the other into of a cell, gland, or organ", - "rdfs:label": "increasesUptakeOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:decreasesUptakeOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two molecular entities where the action or effect of one decreases the rate of uptake of the other into of a cell, gland, or organ", - "rdfs:label": "decreasesUptakeOf", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:regulates,ProcessToProcess", - "@type": "rdf:Property", - "rdfs:comment": null, - "rdfs:label": "regulates,ProcessToProcess", - "schema:domainIncludes": { - "@id": "bts:Occurrent" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:Occurrent" - } - }, - { - "@id": "bts:regulates,EntityToEntity", - "@type": "rdf:Property", - "rdfs:comment": null, - "rdfs:label": "regulates,EntityToEntity", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } - }, - { - "@id": "bts:hasGeneProduct", - "@type": "rdf:Property", - "rdfs:comment": "holds between a gene and a transcribed and/or translated product generated from it", - "rdfs:label": "hasGeneProduct", - "schema:domainIncludes": { - "@id": "bts:Gene" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:GeneProduct" - } - }, - { - "@id": "bts:inPathwayWith", - "@type": "rdf:Property", - "rdfs:comment": "holds between two genes or gene products that are part of in the same biological pathway", - "rdfs:label": "inPathwayWith", - "schema:domainIncludes": { - "@id": "bts:GeneOrGeneProduct" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:GeneOrGeneProduct" - } - }, - { - "@id": "bts:inComplexWith", - "@type": "rdf:Property", - "rdfs:comment": "holds between two genes or gene products that are part of (or code for products that are part of) in the same macromolecular complex", - "rdfs:label": "inComplexWith", - "schema:domainIncludes": { - "@id": "bts:GeneOrGeneProduct" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:GeneOrGeneProduct" - } - }, - { - "@id": "bts:inCellPopulationWith", - "@type": "rdf:Property", - "rdfs:comment": "holds between two genes or gene products that are expressed in the same cell type or population ", - "rdfs:label": "inCellPopulationWith", - "schema:domainIncludes": { - "@id": "bts:GeneOrGeneProduct" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:GeneOrGeneProduct" - } - }, - { - "@id": "bts:geneAssociatedWithCondition", - "@type": "rdf:Property", - "rdfs:comment": "holds between a gene and a disease or phenotypic feature that the gene or its alleles/products may influence, contribute to, or correlate with", - "rdfs:label": "geneAssociatedWithCondition", - "schema:domainIncludes": { - "@id": "bts:Gene" - }, - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "schema:rangeIncludes": { - "@id": "bts:DiseaseOrPhenotypicFeature" - } - }, - { - "@id": "bts:treats", + "@id": "bts:resourceType", "@type": "rdf:Property", - "rdfs:comment": "holds between a therapeutic procedure or chemical substance and a disease or phenotypic feature that it is used to treat", - "rdfs:label": "treats", - "schema:domainIncludes": { - "@id": "bts:Treatment" - }, + "rdfs:comment": "Type of resource. (e.g. animal model, antibody, plasmid, etc.)", + "rdfs:label": "resourceType", + "schema:domainIncludes": [ + { + "@id": "bts:Resource" + } + ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "schema:rangeIncludes": { - "@id": "bts:DiseaseOrPhenotypicFeature" - } + "schema:rangeIncludes": [ + { + "@id": "bts:AnimalModel" + }, + { + "@id": "bts:CellLine" + }, + { + "@id": "bts:Antibody" + }, + { + "@id": "bts:GeneticReagent" + }, + { + "@id": "bts:Biobank" + } + ], + "sms:displayName": "resourceType", + "sms:required": "sms:true", + "sms:validationRules": [] }, { - "@id": "bts:correlatedWith", + "@id": "bts:description", "@type": "rdf:Property", - "rdfs:comment": "holds between a disease or phenotypic feature and a measurable molecular entity that is used as an indicator of the presence or state of the disease or feature.", - "rdfs:label": "correlatedWith", - "schema:domainIncludes": { - "@id": "bts:DiseaseOrPhenotypicFeature" - }, + "rdfs:comment": "Free text description/summary/overview/purpose of the resource.", + "rdfs:label": "description", + "schema:domainIncludes": [ + { + "@id": "bts:Resource" + } + ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } + "sms:displayName": "description", + "sms:required": "sms:false", + "sms:validationRules": [] }, { - "@id": "bts:hasBiomarker", + "@id": "bts:aiSummary", "@type": "rdf:Property", - "rdfs:comment": "holds between a disease or phenotypic feature and a measurable molecular entity that is used as an indicator of the presence or state of the disease or feature.", - "rdfs:label": "hasBiomarker", - "schema:domainIncludes": { - "@id": "bts:DiseaseOrPhenotypicFeature" - }, + "rdfs:comment": "A large language model-generated summary of the resource (currently generated with gpt-3.5-turbo).", + "rdfs:label": "aiSummary", + "schema:domainIncludes": [ + { + "@id": "bts:Resource" + } + ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "schema:rangeIncludes": { - "@id": "bts:MolecularEntity" - } + "sms:displayName": "aiSummary", + "sms:required": "sms:false", + "sms:validationRules": [] }, { - "@id": "bts:biomarkerFor", + "@id": "bts:usageRequirements", "@type": "rdf:Property", - "rdfs:comment": "holds between a measurable molecular entity and a disease or phenotypic feature, where the entity is used as an indicator of the presence or state of the disease or feature.", - "rdfs:label": "biomarkerFor", - "schema:domainIncludes": { - "@id": "bts:MolecularEntity" - }, + "rdfs:comment": "Any known restrictions on use of the resource.", + "rdfs:label": "usageRequirements", + "schema:domainIncludes": [ + { + "@id": "bts:Resource" + } + ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "schema:rangeIncludes": { - "@id": "bts:DiseaseOrPhenotypicFeature" - } + "schema:rangeIncludes": [ + { + "@id": "bts:Datasharingrequired" + }, + { + "@id": "bts:Non-commercialuseonly" + }, + { + "@id": "bts:Re-distributionnotpermitted" + }, + { + "@id": "bts:Generationofgermlinetransmittingchimerasnotpermitted" + }, + { + "@id": "bts:Creationoffunctionalgametesnotpermitted" + }, + { + "@id": "bts:Generationofinterspecieschimerasnotpermitted" + }, + { + "@id": "bts:Humancloningnotpermitted" + }, + { + "@id": "bts:Cannotbeusedfortreatmentpurposes" + }, + { + "@id": "bts:IRBdocumentationrequired" + }, + { + "@id": "bts:Speciallicencingrestrictions(seevendorformoreinformation)" + }, + { + "@id": "bts:Unknown" + } + ], + "sms:displayName": "usageRequirements", + "sms:required": "sms:false", + "sms:validationRules": [ + "list like" + ] }, { - "@id": "bts:expressedIn", + "@id": "bts:howToAcquire", "@type": "rdf:Property", - "rdfs:comment": "holds between a gene or gene product and an anatomical entity in which it is expressed", - "rdfs:label": "expressedIn", - "schema:domainIncludes": { - "@id": "bts:GeneOrGeneProduct" - }, + "rdfs:comment": "How to acquire a particular resource.", + "rdfs:label": "howToAcquire", + "schema:domainIncludes": [ + { + "@id": "bts:Resource" + } + ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "schema:rangeIncludes": { - "@id": "bts:AnatomicalEntity" - } + "sms:displayName": "howToAcquire", + "sms:required": "sms:true", + "sms:validationRules": [] }, { - "@id": "bts:expresses", + "@id": "bts:dateAdded", "@type": "rdf:Property", - "rdfs:comment": "holds between an anatomical entity and gene or gene product that is expressed there", - "rdfs:label": "expresses", - "schema:domainIncludes": { - "@id": "bts:AnatomicalEntity" - }, + "rdfs:comment": "The date that the resource was originally added.", + "rdfs:label": "dateAdded", + "schema:domainIncludes": [ + { + "@id": "bts:Resource" + } + ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "schema:rangeIncludes": { - "@id": "bts:GeneOrGeneProduct" - } + "sms:displayName": "dateAdded", + "sms:required": "sms:true", + "sms:validationRules": [] }, { - "@id": "bts:hasPhenotype", + "@id": "bts:dateModified", "@type": "rdf:Property", - "rdfs:comment": "holds between a biological entity and a phenotype, where a phenotype is construed broadly as any kind of quality of an organism part, a collection of these qualities, or a change in quality or qualities (e.g. abnormally increased temperature). ", - "rdfs:label": "hasPhenotype", - "schema:domainIncludes": { - "@id": "bts:BiologicalEntity" - }, + "rdfs:comment": "The last update of the resource metadata (not including observations).", + "rdfs:label": "dateModified", + "schema:domainIncludes": [ + { + "@id": "bts:Resource" + } + ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "schema:rangeIncludes": { - "@id": "bts:DiseaseOrPhenotypicFeature" - } + "sms:displayName": "dateModified", + "sms:required": "sms:true", + "sms:validationRules": [] }, { - "@id": "bts:precedes", - "@type": "rdf:Property", - "rdfs:comment": "holds between two processes, where one completes before the other begins", - "rdfs:label": "precedes", - "schema:domainIncludes": { - "@id": "bts:Occurrent" - }, + "@id": "bts:GeneticReagentDetails", + "@type": "rdfs:Class", + "rdfs:comment": "Genetic reagents.", + "rdfs:label": "GeneticReagentDetails", + "rdfs:subClassOf": [ + { + "@id": "bts:Thing" + } + ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "schema:rangeIncludes": { - "@id": "bts:Occurrent" - } + "sms:displayName": "geneticReagentDetails", + "sms:required": "sms:false", + "sms:requiresDependency": [ + { + "@id": "bts:Component" + }, + { + "@id": "bts:geneticReagentId" + }, + { + "@id": "bts:insertName" + }, + { + "@id": "bts:insertEntrezId" + }, + { + "@id": "bts:gRNAshRNASequence" + }, + { + "@id": "bts:insertSize" + }, + { + "@id": "bts:insertSpecies" + }, + { + "@id": "bts:nTerminalTag" + }, + { + "@id": "bts:cTerminalTag" + }, + { + "@id": "bts:cloningMethod" + }, + { + "@id": "bts:5primeCloningSite" + }, + { + "@id": "bts:5primeSiteDestroyed" + }, + { + "@id": "bts:3primeCloningSite" + }, + { + "@id": "bts:3primeSiteDestroyed" + }, + { + "@id": "bts:promoter" + }, + { + "@id": "bts:5primer" + }, + { + "@id": "bts:3primer" + }, + { + "@id": "bts:vectorBackbone" + }, + { + "@id": "bts:vectorType" + }, + { + "@id": "bts:backboneSize" + }, + { + "@id": "bts:totalSize" + }, + { + "@id": "bts:bacterialResistance" + }, + { + "@id": "bts:selectableMarker" + }, + { + "@id": "bts:copyNumber" + }, + { + "@id": "bts:growthTemp" + }, + { + "@id": "bts:growthStrain" + }, + { + "@id": "bts:hazardous" + } + ], + "sms:validationRules": [] }, { - "@id": "bts:subclassOf", - "@type": "rdf:Property", - "rdfs:comment": "holds between two classes where the domain class is a specialization of the range class", - "rdfs:label": "subclassOf", - "schema:domainIncludes": { - "@id": "bts:OntologyClass" - }, + "@id": "bts:AntibodyDetails", + "@type": "rdfs:Class", + "rdfs:comment": "A blood protein produced in response to and counteracting a specific antigen. Antibodies combine chemically with substances which the body recognizes as alien, such as bacteria, viruses, and foreign substances in the blood.", + "rdfs:label": "AntibodyDetails", + "rdfs:subClassOf": [ + { + "@id": "bts:Thing" + } + ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "schema:rangeIncludes": { - "@id": "bts:OntologyClass" - } + "sms:displayName": "antibodyDetails", + "sms:required": "sms:false", + "sms:requiresDependency": [ + { + "@id": "bts:Component" + }, + { + "@id": "bts:antibodyId" + }, + { + "@id": "bts:uniprotId" + }, + { + "@id": "bts:targetAntigen" + }, + { + "@id": "bts:clonality" + }, + { + "@id": "bts:cloneId" + }, + { + "@id": "bts:reactiveSpecies" + }, + { + "@id": "bts:conjugate" + }, + { + "@id": "bts:hostOrganism" + } + ], + "sms:validationRules": [] }, { - "@id": "bts:Component", + "@id": "bts:CellLineDetails", "@type": "rdfs:Class", - "rdfs:comment": "Type of submitted information.", - "rdfs:label": "Component", + "rdfs:comment": "A cell culture selected for uniformity from a cell population derived from a usually homogeneous tissue source (such as an organ).", + "rdfs:label": "CellLineDetails", "rdfs:subClassOf": [ { - "@id": "schema:Thing" + "@id": "bts:Thing" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "Component", - "sms:required": "sms:true", + "sms:displayName": "cellLineDetails", + "sms:required": "sms:false", + "sms:requiresComponent": [ + { + "@id": "bts:Donor" + } + ], + "sms:requiresDependency": [ + { + "@id": "bts:Component" + }, + { + "@id": "bts:cellLineId" + }, + { + "@id": "bts:donorId" + }, + { + "@id": "bts:organ" + }, + { + "@id": "bts:tissue" + }, + { + "@id": "bts:cellLineCategory" + }, + { + "@id": "bts:originYear" + }, + { + "@id": "bts:strProfile" + }, + { + "@id": "bts:populationDoublingTime" + }, + { + "@id": "bts:resistance" + }, + { + "@id": "bts:contaminatedMisidentified" + }, + { + "@id": "bts:cellLineGeneticDisorder" + }, + { + "@id": "bts:cellLineManifestation" + } + ], "sms:validationRules": [] }, { - "@id": "bts:Resource", + "@id": "bts:AnimalModelDetails", "@type": "rdfs:Class", - "rdfs:comment": "A tool used in the research process (i.e. animal model, cell line, etc.)", - "rdfs:label": "Resource", + "rdfs:comment": "An animal sufficiently like humans in its anatomy, physiology, or response to a pathogen to be used in medical research in order to obtain results that can be extrapolated to human medicine.", + "rdfs:label": "AnimalModelDetails", "rdfs:subClassOf": [ { "@id": "bts:Thing" @@ -2093,430 +579,536 @@ "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "resource", + "sms:displayName": "animalModelDetails", "sms:required": "sms:false", "sms:requiresComponent": [ { - "@id": "bts:GeneticReagent" + "@id": "bts:Donor" + } + ], + "sms:requiresDependency": [ + { + "@id": "bts:Component" }, { - "@id": "bts:Antibody" + "@id": "bts:animalModelId" }, { - "@id": "bts:CellLine" + "@id": "bts:donorId" }, { - "@id": "bts:AnimalModel" + "@id": "bts:transplantationDonorId" + }, + { + "@id": "bts:animalState" + }, + { + "@id": "bts:backgroundStrain" + }, + { + "@id": "bts:backgroundSubstrain" + }, + { + "@id": "bts:strainNomenclature" + }, + { + "@id": "bts:generation" + }, + { + "@id": "bts:transplantationType" + }, + { + "@id": "bts:animalModelGeneticDisorder" + }, + { + "@id": "bts:animalModelOfManifestation" + } + ], + "sms:validationRules": [] + }, + { + "@id": "bts:BiobankDetails", + "@type": "rdfs:Class", + "rdfs:comment": "A large collection of biological or medical data and tissue samples, amassed for research purposes.", + "rdfs:label": "BiobankDetails", + "rdfs:subClassOf": [ + { + "@id": "bts:Thing" } ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "biobankDetails", + "sms:required": "sms:false", "sms:requiresDependency": [ { "@id": "bts:Component" }, { - "@id": "bts:resourceId" - }, - { - "@id": "bts:geneticReagentId" + "@id": "bts:biobankId" }, { - "@id": "bts:antibodyId" + "@id": "bts:resourceId" }, { - "@id": "bts:cellLineId" + "@id": "bts:biobankName" }, { - "@id": "bts:animalModelId" + "@id": "bts:biobankURL" }, { - "@id": "bts:rrid" + "@id": "bts:specimenType" }, { - "@id": "bts:resourceName" + "@id": "bts:specimenTissueType" }, { - "@id": "bts:synonyms" + "@id": "bts:tumorType" }, { - "@id": "bts:resourceType" + "@id": "bts:diseaseType" }, { - "@id": "bts:description" + "@id": "bts:specimenPreparationMethod" }, { - "@id": "bts:usageRequirements" - }, + "@id": "bts:specimenFormat" + } + ], + "sms:validationRules": [] + }, + { + "@id": "bts:animalModelId", + "@type": "rdf:Property", + "rdfs:comment": "A unique identifier for the animal model.", + "rdfs:label": "animalModelId", + "schema:domainIncludes": [ { - "@id": "bts:howToAcquire" + "@id": "bts:Resource" }, { - "@id": "bts:dateAdded" + "@id": "bts:Mutation" }, { - "@id": "bts:dateModified" + "@id": "bts:AnimalModelDetails" } ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "animalModelId", + "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:resourceId", + "@id": "bts:antibodyId", "@type": "rdf:Property", - "rdfs:comment": "A unique identifier for the resource.", - "rdfs:label": "resourceId", + "rdfs:comment": "A unique identifier for the antibody.", + "rdfs:label": "antibodyId", "schema:domainIncludes": [ { "@id": "bts:Resource" }, { - "@id": "bts:VendorItem" - }, - { - "@id": "bts:Biobank" - }, - { - "@id": "bts:Observation" - }, + "@id": "bts:AntibodyDetails" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "antibodyId", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:cellLineId", + "@type": "rdf:Property", + "rdfs:comment": "A unique identifier for the cell line.", + "rdfs:label": "cellLineId", + "schema:domainIncludes": [ { - "@id": "bts:ResourceApplication" + "@id": "bts:Resource" }, { - "@id": "bts:Development" + "@id": "bts:CellLineDetails" }, { - "@id": "bts:Usage" + "@id": "bts:Mutation" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "resourceId", - "sms:required": "sms:true", + "sms:displayName": "cellLineId", + "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:rrid", + "@id": "bts:geneticReagentId", "@type": "rdf:Property", - "rdfs:comment": "The RRID, a standard resource identifier that will facilitate interoperability with other databases, and is an increasingly-used identifier for publications https://scicrunch.org/resources if available", - "rdfs:label": "rrid", + "rdfs:comment": "A unique identifier for the reagent.", + "rdfs:label": "geneticReagentId", "schema:domainIncludes": [ { "@id": "bts:Resource" + }, + { + "@id": "bts:GeneticReagentDetails" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "rrid", + "sms:displayName": "geneticReagentId", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:resourceName", + "@id": "bts:biobankId", "@type": "rdf:Property", - "rdfs:comment": "The “canonical” name of the resource", - "rdfs:label": "resourceName", + "rdfs:comment": "A unique identifier for the biobank.", + "rdfs:label": "biobankId", "schema:domainIncludes": [ { "@id": "bts:Resource" + }, + { + "@id": "bts:BiobankDetails" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "resourceName", - "sms:required": "sms:true", + "sms:displayName": "biobankId", + "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:synonyms", - "@type": "rdf:Property", - "rdfs:comment": "Synonyms of the resource", - "rdfs:label": "synonyms", - "schema:domainIncludes": [ + "@id": "bts:AnimalModel", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "AnimalModel", + "rdfs:subClassOf": [ { - "@id": "bts:Resource" + "@id": "bts:resourceType" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "synonyms", + "sms:displayName": "Animal Model", "sms:required": "sms:false", - "sms:validationRules": [ - "list" - ] + "sms:requiresDependency": [ + { + "@id": "bts:animalModelId" + } + ], + "sms:validationRules": [] }, { - "@id": "bts:resourceType", - "@type": "rdf:Property", - "rdfs:comment": "Type of resource. (e.g. animal model, antibody, plasmid, etc.)", - "rdfs:label": "resourceType", - "schema:domainIncludes": [ + "@id": "bts:CellLine", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "CellLine", + "rdfs:subClassOf": [ { - "@id": "bts:Resource" + "@id": "bts:resourceType" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "schema:rangeIncludes": [ + "sms:displayName": "Cell Line", + "sms:required": "sms:false", + "sms:requiresDependency": [ { - "@id": "bts:AnimalModel" - }, + "@id": "bts:cellLineId" + } + ], + "sms:validationRules": [] + }, + { + "@id": "bts:Antibody", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Antibody", + "rdfs:subClassOf": [ { - "@id": "bts:CellLine" - }, + "@id": "bts:resourceType" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "Antibody", + "sms:required": "sms:false", + "sms:requiresDependency": [ { - "@id": "bts:Antibody" - }, + "@id": "bts:antibodyId" + } + ], + "sms:validationRules": [] + }, + { + "@id": "bts:GeneticReagent", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "GeneticReagent", + "rdfs:subClassOf": [ { - "@id": "bts:GeneticReagent" - }, + "@id": "bts:resourceType" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "Genetic Reagent", + "sms:required": "sms:false", + "sms:requiresDependency": [ { - "@id": "bts:Biobank" + "@id": "bts:geneticReagentId" + } + ], + "sms:validationRules": [] + }, + { + "@id": "bts:Biobank", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Biobank", + "rdfs:subClassOf": [ + { + "@id": "bts:resourceType" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "Biobank", + "sms:required": "sms:false", + "sms:requiresDependency": [ + { + "@id": "bts:biobankId" + } + ], + "sms:validationRules": [] + }, + { + "@id": "bts:Datasharingrequired", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Datasharingrequired", + "rdfs:subClassOf": [ + { + "@id": "bts:usageRequirements" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "data sharing required", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:Non-commercialuseonly", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Non-commercialuseonly", + "rdfs:subClassOf": [ + { + "@id": "bts:usageRequirements" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "non-commercial use only", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:Re-distributionnotpermitted", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Re-distributionnotpermitted", + "rdfs:subClassOf": [ + { + "@id": "bts:usageRequirements" } ], - "sms:displayName": "resourceType", - "sms:required": "sms:true", + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "re-distribution not permitted", + "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:description", - "@type": "rdf:Property", - "rdfs:comment": "Free text description/summary/overview/purpose of the resource.", - "rdfs:label": "description", - "schema:domainIncludes": [ + "@id": "bts:Generationofgermlinetransmittingchimerasnotpermitted", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Generationofgermlinetransmittingchimerasnotpermitted", + "rdfs:subClassOf": [ { - "@id": "bts:Resource" + "@id": "bts:usageRequirements" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "description", + "sms:displayName": "generation of germ line transmitting chimeras not permitted", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:usageRequirements", - "@type": "rdf:Property", - "rdfs:comment": "Any known restrictions on use of the resource. ", - "rdfs:label": "usageRequirements", - "schema:domainIncludes": [ + "@id": "bts:Creationoffunctionalgametesnotpermitted", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Creationoffunctionalgametesnotpermitted", + "rdfs:subClassOf": [ { - "@id": "bts:Resource" + "@id": "bts:usageRequirements" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "schema:rangeIncludes": [ - { - "@id": "bts:Non-commercialuseonly" - }, - { - "@id": "bts:Re-distributionnotpermitted" - }, - { - "@id": "bts:Generationofgermlinetransmittingchimerasnotpermitted" - }, - { - "@id": "bts:Creationoffunctionalgametesnotpermitted" - }, - { - "@id": "bts:Generationofinterspecieschimerasnotpermitted" - }, - { - "@id": "bts:Humancloningnotpermitted" - }, - { - "@id": "bts:Cannotbeusedfortreatmentpurposes" - }, - { - "@id": "bts:IRBdocumentationrequired" - }, - { - "@id": "bts:Speciallicencingrestrictions(seevendorformoreinformation)" - }, + "sms:displayName": "creation of functional gametes not permitted", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:Generationofinterspecieschimerasnotpermitted", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Generationofinterspecieschimerasnotpermitted", + "rdfs:subClassOf": [ { - "@id": "bts:Unknown" + "@id": "bts:usageRequirements" } ], - "sms:displayName": "usageRequirements", + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "generation of interspecies chimeras not permitted", "sms:required": "sms:false", - "sms:validationRules": [ - "list" - ] + "sms:validationRules": [] }, { - "@id": "bts:howToAcquire", - "@type": "rdf:Property", - "rdfs:comment": "How to acquire a particular resource. ", - "rdfs:label": "howToAcquire", - "schema:domainIncludes": [ + "@id": "bts:Humancloningnotpermitted", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Humancloningnotpermitted", + "rdfs:subClassOf": [ { - "@id": "bts:Resource" + "@id": "bts:usageRequirements" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "howToAcquire", - "sms:required": "sms:true", + "sms:displayName": "human cloning not permitted", + "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:dateAdded", - "@type": "rdf:Property", - "rdfs:comment": "The date that the resource was originally added.", - "rdfs:label": "dateAdded", - "schema:domainIncludes": [ + "@id": "bts:Cannotbeusedfortreatmentpurposes", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Cannotbeusedfortreatmentpurposes", + "rdfs:subClassOf": [ { - "@id": "bts:Resource" + "@id": "bts:usageRequirements" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "dateAdded", - "sms:required": "sms:true", + "sms:displayName": "cannot be used for treatment purposes", + "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:dateModified", - "@type": "rdf:Property", - "rdfs:comment": "The last update of the resource metadata (not including observations).", - "rdfs:label": "dateModified", - "schema:domainIncludes": [ + "@id": "bts:IRBdocumentationrequired", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "IRBdocumentationrequired", + "rdfs:subClassOf": [ { - "@id": "bts:Resource" + "@id": "bts:usageRequirements" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "dateModified", - "sms:required": "sms:true", + "sms:displayName": "IRB documentation required", + "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:GeneticReagent", + "@id": "bts:Speciallicencingrestrictions(seevendorformoreinformation)", "@type": "rdfs:Class", - "rdfs:comment": "Genetic reagents.", - "rdfs:label": "GeneticReagent", + "rdfs:comment": "TBD", + "rdfs:label": "Speciallicencingrestrictions(seevendorformoreinformation)", "rdfs:subClassOf": [ { - "@id": "bts:GeneticReagent" + "@id": "bts:usageRequirements" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "geneticReagent", + "sms:displayName": "special licencing restrictions (see vendor for more information)", "sms:required": "sms:false", - "sms:requiresDependency": [ - { - "@id": "bts:Component" - }, - { - "@id": "bts:geneticReagentId" - }, - { - "@id": "bts:insertName" - }, - { - "@id": "bts:insertEntrezId" - }, - { - "@id": "bts:gRNAshRNASequence" - }, - { - "@id": "bts:insertSize" - }, - { - "@id": "bts:insertSpecies" - }, - { - "@id": "bts:nTerminalTag" - }, - { - "@id": "bts:cTerminalTag" - }, - { - "@id": "bts:cloningMethod" - }, + "sms:validationRules": [] + }, + { + "@id": "bts:Unknown", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Unknown", + "rdfs:subClassOf": [ { - "@id": "bts:5primeCloningSite" + "@id": "bts:clonality" }, { "@id": "bts:5primeSiteDestroyed" }, - { - "@id": "bts:3primeCloningSite" - }, { "@id": "bts:3primeSiteDestroyed" }, { - "@id": "bts:promoter" - }, - { - "@id": "bts:5primer" - }, - { - "@id": "bts:3primer" - }, - { - "@id": "bts:vectorBackbone" - }, - { - "@id": "bts:vectorType" - }, - { - "@id": "bts:backboneSize" - }, - { - "@id": "bts:totalSize" + "@id": "bts:copyNumber" }, { - "@id": "bts:bacterialResistance" + "@id": "bts:hazardous" }, { - "@id": "bts:selectableMarker" + "@id": "bts:hostOrganism" }, { - "@id": "bts:copyNumber" + "@id": "bts:sex" }, { - "@id": "bts:growthTemp" + "@id": "bts:cloningMethod" }, { - "@id": "bts:growthStrain" + "@id": "bts:usageRequirements" }, { - "@id": "bts:hazardous" - } - ], - "sms:validationRules": [] - }, - { - "@id": "bts:geneticReagentId", - "@type": "rdf:Property", - "rdfs:comment": "A unique identifier for the reagent.", - "rdfs:label": "geneticReagentId", - "schema:domainIncludes": [ - { - "@id": "bts:Resource" + "@id": "bts:mutationMethod" }, { - "@id": "bts:GeneticReagent" + "@id": "bts:reactiveSpecies" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "geneticReagentId", - "sms:required": "sms:true", + "sms:displayName": "Unknown", + "sms:required": "sms:false", "sms:validationRules": [] }, { @@ -2526,7 +1118,7 @@ "rdfs:label": "insertName", "schema:domainIncludes": [ { - "@id": "bts:GeneticReagent" + "@id": "bts:GeneticReagentDetails" } ], "schema:isPartOf": { @@ -2543,24 +1135,24 @@ "rdfs:label": "insertEntrezId", "schema:domainIncludes": [ { - "@id": "bts:GeneticReagent" + "@id": "bts:GeneticReagentDetails" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, "sms:displayName": "insertEntrezId", - "sms:required": "sms:true", + "sms:required": "sms:false", "sms:validationRules": [] }, { "@id": "bts:gRNAshRNASequence", "@type": "rdf:Property", - "rdfs:comment": "The sequence of the gRNA or shRNA for the gene insert, if present. ", + "rdfs:comment": "The sequence of the gRNA or shRNA for the gene insert, if present.", "rdfs:label": "gRNAshRNASequence", "schema:domainIncludes": [ { - "@id": "bts:GeneticReagent" + "@id": "bts:GeneticReagentDetails" } ], "schema:isPartOf": { @@ -2577,7 +1169,7 @@ "rdfs:label": "insertSize", "schema:domainIncludes": [ { - "@id": "bts:GeneticReagent" + "@id": "bts:GeneticReagentDetails" } ], "schema:isPartOf": { @@ -2594,7 +1186,7 @@ "rdfs:label": "insertSpecies", "schema:domainIncludes": [ { - "@id": "bts:GeneticReagent" + "@id": "bts:GeneticReagentDetails" } ], "schema:isPartOf": { @@ -2614,7 +1206,7 @@ "sms:displayName": "insertSpecies", "sms:required": "sms:true", "sms:validationRules": [ - "list" + "list like" ] }, { @@ -2624,7 +1216,7 @@ "rdfs:label": "nTerminalTag", "schema:domainIncludes": [ { - "@id": "bts:GeneticReagent" + "@id": "bts:GeneticReagentDetails" } ], "schema:isPartOf": { @@ -2633,7 +1225,7 @@ "sms:displayName": "nTerminalTag", "sms:required": "sms:false", "sms:validationRules": [ - "list" + "list like" ] }, { @@ -2643,7 +1235,7 @@ "rdfs:label": "cTerminalTag", "schema:domainIncludes": [ { - "@id": "bts:GeneticReagent" + "@id": "bts:GeneticReagentDetails" } ], "schema:isPartOf": { @@ -2652,7 +1244,7 @@ "sms:displayName": "cTerminalTag", "sms:required": "sms:false", "sms:validationRules": [ - "list" + "list like" ] }, { @@ -2662,7 +1254,7 @@ "rdfs:label": "cloningMethod", "schema:domainIncludes": [ { - "@id": "bts:GeneticReagent" + "@id": "bts:GeneticReagentDetails" } ], "schema:isPartOf": { @@ -2699,7 +1291,7 @@ "rdfs:label": "5primeCloningSite", "schema:domainIncludes": [ { - "@id": "bts:GeneticReagent" + "@id": "bts:GeneticReagentDetails" } ], "schema:isPartOf": { @@ -2707,11 +1299,6 @@ }, "sms:displayName": "5primeCloningSite", "sms:required": "sms:false", - "sms:requiresDependency": [ - { - "@id": "bts:cloningMethod" - } - ], "sms:validationRules": [] }, { @@ -2721,7 +1308,7 @@ "rdfs:label": "5primeSiteDestroyed", "schema:domainIncludes": [ { - "@id": "bts:GeneticReagent" + "@id": "bts:GeneticReagentDetails" } ], "schema:isPartOf": { @@ -2749,7 +1336,7 @@ "rdfs:label": "3primeCloningSite", "schema:domainIncludes": [ { - "@id": "bts:GeneticReagent" + "@id": "bts:GeneticReagentDetails" } ], "schema:isPartOf": { @@ -2757,11 +1344,6 @@ }, "sms:displayName": "3primeCloningSite", "sms:required": "sms:false", - "sms:requiresDependency": [ - { - "@id": "bts:cloningMethod" - } - ], "sms:validationRules": [] }, { @@ -2771,7 +1353,7 @@ "rdfs:label": "3primeSiteDestroyed", "schema:domainIncludes": [ { - "@id": "bts:GeneticReagent" + "@id": "bts:GeneticReagentDetails" } ], "schema:isPartOf": { @@ -2799,7 +1381,7 @@ "rdfs:label": "promoter", "schema:domainIncludes": [ { - "@id": "bts:GeneticReagent" + "@id": "bts:GeneticReagentDetails" } ], "schema:isPartOf": { @@ -2816,7 +1398,7 @@ "rdfs:label": "5primer", "schema:domainIncludes": [ { - "@id": "bts:GeneticReagent" + "@id": "bts:GeneticReagentDetails" } ], "schema:isPartOf": { @@ -2833,7 +1415,7 @@ "rdfs:label": "3primer", "schema:domainIncludes": [ { - "@id": "bts:GeneticReagent" + "@id": "bts:GeneticReagentDetails" } ], "schema:isPartOf": { @@ -2850,7 +1432,7 @@ "rdfs:label": "vectorBackbone", "schema:domainIncludes": [ { - "@id": "bts:GeneticReagent" + "@id": "bts:GeneticReagentDetails" } ], "schema:isPartOf": { @@ -2867,7 +1449,7 @@ "rdfs:label": "vectorType", "schema:domainIncludes": [ { - "@id": "bts:GeneticReagent" + "@id": "bts:GeneticReagentDetails" } ], "schema:isPartOf": { @@ -2928,6 +1510,9 @@ { "@id": "bts:TransferVector" }, + { + "@id": "bts:TransposonVector" + }, { "@id": "bts:Unspecified" }, @@ -2938,7 +1523,7 @@ "sms:displayName": "vectorType", "sms:required": "sms:false", "sms:validationRules": [ - "list" + "list like" ] }, { @@ -2948,7 +1533,7 @@ "rdfs:label": "backboneSize", "schema:domainIncludes": [ { - "@id": "bts:GeneticReagent" + "@id": "bts:GeneticReagentDetails" } ], "schema:isPartOf": { @@ -2965,7 +1550,7 @@ "rdfs:label": "totalSize", "schema:domainIncludes": [ { - "@id": "bts:GeneticReagent" + "@id": "bts:GeneticReagentDetails" } ], "schema:isPartOf": { @@ -2982,7 +1567,7 @@ "rdfs:label": "bacterialResistance", "schema:domainIncludes": [ { - "@id": "bts:GeneticReagent" + "@id": "bts:GeneticReagentDetails" } ], "schema:isPartOf": { @@ -3070,7 +1655,7 @@ "rdfs:label": "selectableMarker", "schema:domainIncludes": [ { - "@id": "bts:GeneticReagent" + "@id": "bts:GeneticReagentDetails" } ], "schema:isPartOf": { @@ -3086,6 +1671,12 @@ { "@id": "bts:Hygromycin" }, + { + "@id": "bts:Kanamycin" + }, + { + "@id": "bts:Chloramphenicol" + }, { "@id": "bts:Zeocin" }, @@ -3101,6 +1692,9 @@ { "@id": "bts:LEU1" }, + { + "@id": "bts:LEU2" + }, { "@id": "bts:URA3" }, @@ -3125,7 +1719,7 @@ "rdfs:label": "copyNumber", "schema:domainIncludes": [ { - "@id": "bts:GeneticReagent" + "@id": "bts:GeneticReagentDetails" } ], "schema:isPartOf": { @@ -3153,7 +1747,7 @@ "rdfs:label": "growthTemp", "schema:domainIncludes": [ { - "@id": "bts:GeneticReagent" + "@id": "bts:GeneticReagentDetails" } ], "schema:isPartOf": { @@ -3181,7 +1775,7 @@ "rdfs:label": "growthStrain", "schema:domainIncludes": [ { - "@id": "bts:GeneticReagent" + "@id": "bts:GeneticReagentDetails" } ], "schema:isPartOf": { @@ -3218,7 +1812,7 @@ "rdfs:label": "hazardous", "schema:domainIncludes": [ { - "@id": "bts:GeneticReagent" + "@id": "bts:GeneticReagentDetails" } ], "schema:isPartOf": { @@ -3240,1693 +1834,1567 @@ "sms:validationRules": [] }, { - "@id": "bts:VendorItem", + "@id": "bts:Homosapiens", "@type": "rdfs:Class", - "rdfs:comment": "The resource item associated with a vendor.", - "rdfs:label": "VendorItem", + "rdfs:comment": "TBD", + "rdfs:label": "Homosapiens", "rdfs:subClassOf": [ { - "@id": "bts:VendorItem" + "@id": "bts:insertSpecies" + }, + { + "@id": "bts:species" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "vendorItem", + "sms:displayName": "Homo sapiens", "sms:required": "sms:false", - "sms:requiresComponent": [ + "sms:validationRules": [] + }, + { + "@id": "bts:Musmusculus", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Musmusculus", + "rdfs:subClassOf": [ { - "@id": "bts:Resource" + "@id": "bts:insertSpecies" }, { - "@id": "bts:Vendor" + "@id": "bts:species" } ], - "sms:requiresDependency": [ + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "Mus musculus", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:Rattusnorvegicus", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Rattusnorvegicus", + "rdfs:subClassOf": [ { - "@id": "bts:Component" + "@id": "bts:insertSpecies" }, { - "@id": "bts:vendorItemId" + "@id": "bts:species" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "Rattus norvegicus", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:RestrictionEnzyme", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "RestrictionEnzyme", + "rdfs:subClassOf": [ + { + "@id": "bts:cloningMethod" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "Restriction Enzyme", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:TOPOcloning", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "TOPOcloning", + "rdfs:subClassOf": [ + { + "@id": "bts:cloningMethod" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "TOPO cloning", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:GatewayCloning", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "GatewayCloning", + "rdfs:subClassOf": [ + { + "@id": "bts:cloningMethod" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "Gateway Cloning", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:LigationIndependentCloning", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "LigationIndependentCloning", + "rdfs:subClassOf": [ + { + "@id": "bts:cloningMethod" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "Ligation Independent Cloning", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:GibsonCloning", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "GibsonCloning", + "rdfs:subClassOf": [ + { + "@id": "bts:cloningMethod" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "Gibson Cloning", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:Yes", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Yes", + "rdfs:subClassOf": [ + { + "@id": "bts:5primeSiteDestroyed" }, { - "@id": "bts:vendorId" + "@id": "bts:3primeSiteDestroyed" }, { - "@id": "bts:resourceId" + "@id": "bts:hazardous" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "Yes", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:No", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "No", + "rdfs:subClassOf": [ + { + "@id": "bts:5primeSiteDestroyed" }, { - "@id": "bts:catalogNumber" + "@id": "bts:3primeSiteDestroyed" }, { - "@id": "bts:catalogNumberURL" + "@id": "bts:hazardous" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "No", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:MammalianExpression", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "MammalianExpression", + "rdfs:subClassOf": [ + { + "@id": "bts:vectorType" } ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "Mammalian Expression", + "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:vendorItemId", - "@type": "rdf:Property", - "rdfs:comment": "A unique identifier for the resource associated with a vendor. ", - "rdfs:label": "vendorItemId", - "schema:domainIncludes": [ + "@id": "bts:BacterialExpression", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "BacterialExpression", + "rdfs:subClassOf": [ + { + "@id": "bts:vectorType" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "Bacterial Expression", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:GatewayEntryClone", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "GatewayEntryClone", + "rdfs:subClassOf": [ + { + "@id": "bts:vectorType" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "Gateway Entry Clone", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:Lentiviral", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Lentiviral", + "rdfs:subClassOf": [ { - "@id": "bts:VendorItem" + "@id": "bts:vectorType" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "vendorItemId", - "sms:required": "sms:true", + "sms:displayName": "Lentiviral", + "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:catalogNumber", - "@type": "rdf:Property", - "rdfs:comment": "The catalog number associated with the resource pertaining to the vendor that sells the resource.", - "rdfs:label": "catalogNumber", - "schema:domainIncludes": [ + "@id": "bts:Adenoviral", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Adenoviral", + "rdfs:subClassOf": [ { - "@id": "bts:VendorItem" + "@id": "bts:vectorType" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "catalogNumber", - "sms:required": "sms:true", + "sms:displayName": "Adenoviral", + "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:catalogNumberURL", - "@type": "rdf:Property", - "rdfs:comment": "The url linking to the resource on the vendor's website. ", - "rdfs:label": "catalogNumberURL", - "schema:domainIncludes": [ + "@id": "bts:AAV", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "AAV", + "rdfs:subClassOf": [ { - "@id": "bts:VendorItem" + "@id": "bts:vectorType" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "catalogNumberURL", + "sms:displayName": "AAV", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:Vendor", + "@id": "bts:RNAi", "@type": "rdfs:Class", - "rdfs:comment": "A person or compnay offering the resource for sale.", - "rdfs:label": "Vendor", + "rdfs:comment": "TBD", + "rdfs:label": "RNAi", "rdfs:subClassOf": [ { - "@id": "bts:Vendor" + "@id": "bts:vectorType" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "vendor", + "sms:displayName": "RNAi", "sms:required": "sms:false", - "sms:requiresDependency": [ - { - "@id": "bts:Component" - }, - { - "@id": "bts:vendorId" - }, - { - "@id": "bts:vendorName" - }, - { - "@id": "bts:vendorURL" - } - ], "sms:validationRules": [] }, { - "@id": "bts:vendorId", - "@type": "rdf:Property", - "rdfs:comment": "A unique identifier for the vendor.", - "rdfs:label": "vendorId", - "schema:domainIncludes": [ - { - "@id": "bts:VendorItem" - }, + "@id": "bts:Luciferase", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Luciferase", + "rdfs:subClassOf": [ { - "@id": "bts:Vendor" + "@id": "bts:vectorType" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "vendorId", - "sms:required": "sms:true", + "sms:displayName": "Luciferase", + "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:vendorName", - "@type": "rdf:Property", - "rdfs:comment": "The name of the vendor.", - "rdfs:label": "vendorName", - "schema:domainIncludes": [ + "@id": "bts:Cre/Lox", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Cre/Lox", + "rdfs:subClassOf": [ { - "@id": "bts:Vendor" + "@id": "bts:vectorType" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "vendorName", + "sms:displayName": "Cre/Lox", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:vendorURL", - "@type": "rdf:Property", - "rdfs:comment": "The vendor website url associated with the resource.", - "rdfs:label": "vendorURL", - "schema:domainIncludes": [ + "@id": "bts:YeastExpression", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "YeastExpression", + "rdfs:subClassOf": [ { - "@id": "bts:Vendor" + "@id": "bts:vectorType" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "vendorURL", + "sms:displayName": "Yeast Expression", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:Biobank", + "@id": "bts:WormExpression", "@type": "rdfs:Class", - "rdfs:comment": "A large collection of biological or medical data and tissue samples, amassed for research purposes.", - "rdfs:label": "Biobank", + "rdfs:comment": "TBD", + "rdfs:label": "WormExpression", "rdfs:subClassOf": [ { - "@id": "bts:Biobank" + "@id": "bts:vectorType" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "biobank", + "sms:displayName": "Worm Expression", "sms:required": "sms:false", - "sms:requiresComponent": [ - { - "@id": "bts:Resource" - } - ], - "sms:requiresDependency": [ - { - "@id": "bts:Component" - }, - { - "@id": "bts:biobankId" - }, - { - "@id": "bts:resourceId" - }, - { - "@id": "bts:biobankName" - }, - { - "@id": "bts:biobankURL" - }, - { - "@id": "bts:specimenType" - }, - { - "@id": "bts:specimenTissueType" - }, - { - "@id": "bts:tumorType" - }, - { - "@id": "bts:diseaseType" - }, - { - "@id": "bts:specimenPreparationMethod" - }, + "sms:validationRules": [] + }, + { + "@id": "bts:InsectExpression", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "InsectExpression", + "rdfs:subClassOf": [ { - "@id": "bts:specimenFormat" + "@id": "bts:vectorType" } ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "Insect Expression", + "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:biobankName", - "@type": "rdf:Property", - "rdfs:comment": "The name of the biobank. ", - "rdfs:label": "biobankName", - "schema:domainIncludes": [ + "@id": "bts:PlantExpression", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "PlantExpression", + "rdfs:subClassOf": [ { - "@id": "bts:Biobank" + "@id": "bts:vectorType" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "biobankName", - "sms:required": "sms:true", + "sms:displayName": "Plant Expression", + "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:biobankId", - "@type": "rdf:Property", - "rdfs:comment": "A unique identifier for the biobank.", - "rdfs:label": "biobankId", - "schema:domainIncludes": [ + "@id": "bts:MouseTargeting", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "MouseTargeting", + "rdfs:subClassOf": [ { - "@id": "bts:Biobank" + "@id": "bts:vectorType" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "biobankId", - "sms:required": "sms:true", + "sms:displayName": "Mouse Targeting", + "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:biobankURL", - "@type": "rdf:Property", - "rdfs:comment": "A URL for the biobank landing page.", - "rdfs:label": "biobankURL", - "schema:domainIncludes": [ + "@id": "bts:CRISPR", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "CRISPR", + "rdfs:subClassOf": [ { - "@id": "bts:Biobank" + "@id": "bts:vectorType" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "biobankURL", - "sms:required": "sms:true", + "sms:displayName": "CRISPR", + "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:specimenType", - "@type": "rdf:Property", - "rdfs:comment": "The types of specimens that are banked.", - "rdfs:label": "specimenType", - "schema:domainIncludes": [ + "@id": "bts:TALEN", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "TALEN", + "rdfs:subClassOf": [ { - "@id": "bts:Biobank" + "@id": "bts:vectorType" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "schema:rangeIncludes": [ - { - "@id": "bts:Humantissue" - }, - { - "@id": "bts:Xenografttumors" - }, + "sms:displayName": "TALEN", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:SyntheticBiology", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "SyntheticBiology", + "rdfs:subClassOf": [ { - "@id": "bts:Celllines" + "@id": "bts:vectorType" } ], - "sms:displayName": "specimenType", - "sms:required": "sms:true", - "sms:validationRules": [ - "list" - ] + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "Synthetic Biology", + "sms:required": "sms:false", + "sms:validationRules": [] }, { - "@id": "bts:specimenTissueType", - "@type": "rdf:Property", - "rdfs:comment": "The types of tissues that are banked.", - "rdfs:label": "specimenTissueType", - "schema:domainIncludes": [ + "@id": "bts:TransferVector", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "TransferVector", + "rdfs:subClassOf": [ { - "@id": "bts:Biobank" + "@id": "bts:vectorType" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - 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"sms:displayName": "resourceApplicationId", - "sms:required": "sms:true", + "sms:displayName": "TRP1", + "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:source", - "@type": "rdf:Property", - "rdfs:comment": "The source of resource application information (e.g. Vendor, Community)", - "rdfs:label": "source", - "schema:domainIncludes": [ + "@id": "bts:LEU1", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "LEU1", + "rdfs:subClassOf": [ { - "@id": "bts:ResourceApplication" + "@id": "bts:selectableMarker" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "schema:rangeIncludes": [ - { - "@id": "bts:Community-reported" - }, - { - "@id": "bts:Investigator-reported" - }, - { - "@id": "bts:Vendor-reported" - } - ], - "sms:displayName": "source", - "sms:required": "sms:true", + "sms:displayName": "LEU1", + "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:applications", - "@type": "rdf:Property", - "rdfs:comment": "One or more uses for the resource (e.g. western blot, immunofluorescence)", - "rdfs:label": "applications", - "schema:domainIncludes": [ + "@id": "bts:LEU2", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "LEU2", + "rdfs:subClassOf": [ { - "@id": "bts:ResourceApplication" + "@id": "bts:selectableMarker" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "schema:rangeIncludes": [ - { - "@id": "bts:WesternBlot" - }, - { - "@id": "bts:Immunofluorescence" - }, - { - "@id": "bts:ELISA" - }, - { - "@id": "bts:Immunohistochemistry" - }, - { - "@id": "bts:Immunoprecipitation" - }, - { - "@id": "bts:TumorGrowthStudies" - }, - { - "@id": "bts:Immunohistochemistry(Paraffin-Embedded)" - }, - { - "@id": "bts:Immunocytochemistry" - }, - { - "@id": "bts:Immunohistochemistry(FrozenSections)" - }, - { - "@id": "bts:FlowCytometry" - }, - { - "@id": "bts:AffinityPurification" - }, - { - "@id": "bts:Microarray" - } - ], - "sms:displayName": "applications", - "sms:required": "sms:true", - "sms:validationRules": [ - "list" - ] + "sms:displayName": "LEU2", + "sms:required": "sms:false", + "sms:validationRules": [] }, { - "@id": "bts:links", - "@type": "rdf:Property", - "rdfs:comment": "shareable links related to the resource", - "rdfs:label": "links", - "schema:domainIncludes": [ + "@id": "bts:URA3", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "URA3", + "rdfs:subClassOf": [ { - "@id": "bts:ResourceApplication" + "@id": "bts:selectableMarker" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "links", + "sms:displayName": "URA3", "sms:required": "sms:false", - "sms:validationRules": [ - "list" - ] + "sms:validationRules": [] }, { - "@id": "bts:Antibody", + "@id": "bts:HIS3", "@type": "rdfs:Class", - "rdfs:comment": "A blood protein produced in response to and counteracting a specific antigen. Antibodies combine chemically with substances which the body recognizes as alien, such as bacteria, viruses, and foreign substances in the blood.", - "rdfs:label": "Antibody", + "rdfs:comment": "TBD", + "rdfs:label": "HIS3", "rdfs:subClassOf": [ { - "@id": "bts:Antibody" + "@id": "bts:selectableMarker" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "antibody", + "sms:displayName": "HIS3", "sms:required": "sms:false", - "sms:requiresDependency": [ - { - "@id": "bts:Component" - }, - { - "@id": "bts:antibodyId" - }, - { - "@id": "bts:uniprotId" - }, - { - "@id": "bts:targetAntigen" - }, - { - "@id": "bts:clonality" - }, - { - "@id": "bts:cloneId" - }, - { - "@id": "bts:reactiveSpecies" - }, - { - "@id": "bts:conjugate" - }, - { - "@id": "bts:hostOrganism" - } - ], "sms:validationRules": [] }, { - "@id": "bts:antibodyId", - "@type": "rdf:Property", - "rdfs:comment": "A unique identifier for the antibody.", - "rdfs:label": "antibodyId", - "schema:domainIncludes": [ - { - "@id": "bts:Resource" - }, + "@id": "bts:Basta", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Basta", + "rdfs:subClassOf": [ { - "@id": "bts:AntibodyId" + "@id": "bts:selectableMarker" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "antibodyId", - "sms:required": "sms:true", + "sms:displayName": "Basta", + "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:uniprotId", - "@type": "rdf:Property", - "rdfs:comment": "The uniprotId of the antibody.", - "rdfs:label": "uniprotId", - "schema:domainIncludes": [ + "@id": "bts:HighCopy", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "HighCopy", + "rdfs:subClassOf": [ { - "@id": "bts:AntibodyId" + "@id": "bts:copyNumber" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "uniprotId", - "sms:required": "sms:true", + "sms:displayName": "High Copy", + "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:targetAntigen", - "@type": "rdf:Property", - "rdfs:comment": "Antigen that is targeted by antibody. (e.g. Neurofibromin 1 human)", - "rdfs:label": "targetAntigen", - "schema:domainIncludes": [ + "@id": "bts:LowCopy", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "LowCopy", + "rdfs:subClassOf": [ { - "@id": "bts:AntibodyId" + "@id": "bts:copyNumber" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "targetAntigen", - "sms:required": "sms:true", + "sms:displayName": "Low Copy", + "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:clonality", - "@type": "rdf:Property", - "rdfs:comment": "They type of clonality of the antibody", - "rdfs:label": "clonality", - "schema:domainIncludes": [ + "@id": "bts:37C", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "37C", + "rdfs:subClassOf": [ { - "@id": "bts:AntibodyId" + "@id": "bts:growthTemp" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "schema:rangeIncludes": [ - { - "@id": "bts:Unknown" - }, - { - "@id": "bts:Cocktail" - }, - { - "@id": "bts:Control" - }, - { - "@id": "bts:IsotypeControl" - }, - { - "@id": "bts:Monoclonal" - }, - { - "@id": "bts:MonoclonalSecondary" - }, - { - "@id": "bts:Polyclonal" - }, - { - "@id": "bts:PolyclonalSecondary" - }, - { - "@id": "bts:OligoClonal" - }, - { - "@id": "bts:Recombinant" - }, - { - "@id": "bts:RecombinantMonoclonal" - }, - { - "@id": "bts:RecombinantMonoclonalSecondary" - }, - { - "@id": "bts:RecombinantPolyclonal" - }, + "sms:displayName": "37 C", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:30C", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "30C", + "rdfs:subClassOf": [ { - "@id": "bts:RecombinantPolyclonalSecondary" + "@id": "bts:growthTemp" } ], - "sms:displayName": "clonality", - "sms:required": "sms:true", + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "30 C", + "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:cloneId", - "@type": "rdf:Property", - "rdfs:comment": "Identification of clone (e.g. 2D1)", - "rdfs:label": "cloneId", - "schema:domainIncludes": [ + "@id": "bts:RoomTemperature", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "RoomTemperature", + "rdfs:subClassOf": [ { - "@id": "bts:AntibodyId" + "@id": "bts:growthTemp" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "cloneId", + "sms:displayName": "Room Temperature", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:reactiveSpecies", - "@type": "rdf:Property", - "rdfs:comment": "Species the antibody has been shown to crossreact with the target protein. ", - "rdfs:label": "reactiveSpecies", - "schema:domainIncludes": [ + "@id": "bts:DH5alpha", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "DH5alpha", + "rdfs:subClassOf": [ { - "@id": "bts:AntibodyId" + "@id": "bts:growthStrain" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "schema:rangeIncludes": [ - { - "@id": "bts:Avian" - }, - { - "@id": "bts:Bovine" - }, - { - "@id": "bts:Canine" - }, - { - "@id": "bts:Chicken" - }, - { - "@id": "bts:Cow" - }, - { - "@id": "bts:Dog" - }, - { - "@id": "bts:Donkey" - }, - { - "@id": "bts:Feline" - }, - { - "@id": "bts:Fish" - }, - { - "@id": "bts:Guineapig" - }, - { - "@id": "bts:Hamster" - }, - { - "@id": "bts:Human" - }, - { - "@id": "bts:Monkey" - }, - { - "@id": "bts:Mouse" - }, - { - "@id": "bts:Non-humanprimate" - }, - { - "@id": "bts:Other" - }, - { - "@id": "bts:Pig" - }, - { - "@id": "bts:Porcine" - }, - { - "@id": "bts:Rabbit" - }, - { - "@id": "bts:Rat" - }, - { - "@id": "bts:Rodent" - }, - { - "@id": "bts:Sheep" - }, - { - "@id": "bts:Simian" - }, - { - "@id": "bts:Zebrafish" - } - ], - "sms:displayName": "reactiveSpecies", - "sms:required": "sms:true", - "sms:validationRules": [ - "list" - ] + "sms:displayName": "DH5alpha", + "sms:required": "sms:false", + "sms:validationRules": [] }, { - "@id": "bts:conjugate", - "@type": "rdf:Property", - "rdfs:comment": "Is the antibody conjugated or nonconjugated", - "rdfs:label": "conjugate", - "schema:domainIncludes": [ + "@id": "bts:DH10B", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "DH10B", + "rdfs:subClassOf": [ { - "@id": "bts:AntibodyId" + "@id": "bts:growthStrain" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "schema:rangeIncludes": [ - { - "@id": "bts:Conjugated" - }, + "sms:displayName": "DH10B", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:NEBStable", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "NEBStable", + "rdfs:subClassOf": [ { - "@id": "bts:Nonconjugated" + "@id": "bts:growthStrain" } ], - "sms:displayName": "conjugate", - "sms:required": "sms:true", + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "NEB Stable", + "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:hostOrganism", - "@type": "rdf:Property", - "rdfs:comment": "The species of the organism that hosts the antibody", - "rdfs:label": "hostOrganism", - "schema:domainIncludes": [ + "@id": "bts:CcdbSurvival", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "CcdbSurvival", + "rdfs:subClassOf": [ { - "@id": "bts:AntibodyId" + "@id": "bts:growthStrain" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "schema:rangeIncludes": [ - { - "@id": "bts:Mouse" - }, + "sms:displayName": "ccdb Survival", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:Pir1", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Pir1", + "rdfs:subClassOf": [ { - "@id": "bts:Rabbit" + "@id": "bts:growthStrain" } ], - "sms:displayName": "hostOrganism", - "sms:required": "sms:true", + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "Pir1", + "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:Donor", + "@id": "bts:VendorItem", "@type": "rdfs:Class", - "rdfs:comment": "A person, animal, etc. who is the contributor of the resource.", - "rdfs:label": "Donor", + "rdfs:comment": "The resource item associated with a vendor.", + "rdfs:label": "VendorItem", "rdfs:subClassOf": [ { - "@id": "bts:Donor" + "@id": "bts:Thing" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "donor", + "sms:displayName": "vendorItem", "sms:required": "sms:false", - "sms:requiresDependency": [ + "sms:requiresComponent": [ { - "@id": "bts:Component" + "@id": "bts:Resource" }, { - "@id": "bts:donorId" - }, + "@id": "bts:Vendor" + } + ], + "sms:requiresDependency": [ { - "@id": "bts:parentDonorId" + "@id": "bts:Component" }, { - "@id": "bts:transplantationDonorId" + "@id": "bts:vendorItemId" }, { - "@id": "bts:species" + "@id": "bts:vendorId" }, { - "@id": "bts:sex" + "@id": "bts:resourceId" }, { - "@id": "bts:age" + "@id": "bts:catalogNumber" }, { - "@id": "bts:race" + "@id": "bts:catalogNumberURL" } ], "sms:validationRules": [] }, { - "@id": "bts:donorId", + "@id": "bts:vendorItemId", "@type": "rdf:Property", - "rdfs:comment": "A uniqe identifier for donor.", - "rdfs:label": "donorId", + "rdfs:comment": "A unique identifier for the resource associated with a vendor.", + "rdfs:label": "vendorItemId", "schema:domainIncludes": [ { - "@id": "bts:Donor" - }, + "@id": "bts:VendorItem" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "vendorItemId", + "sms:required": "sms:true", + "sms:validationRules": [] + }, + { + "@id": "bts:vendorId", + "@type": "rdf:Property", + "rdfs:comment": "A unique identifier for the vendor.", + "rdfs:label": "vendorId", + "schema:domainIncludes": [ { - "@id": "bts:CellLine" + "@id": "bts:VendorItem" }, { - "@id": "bts:AnimalModel" + "@id": "bts:Vendor" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "donorId", + "sms:displayName": "vendorId", "sms:required": "sms:true", "sms:validationRules": [] }, { - "@id": "bts:parentDonorId", + "@id": "bts:catalogNumber", "@type": "rdf:Property", - "rdfs:comment": "The ID of the parent donor.", - "rdfs:label": "parentDonorId", + "rdfs:comment": "The catalog number associated with the resource pertaining to the vendor that sells the resource.", + "rdfs:label": "catalogNumber", "schema:domainIncludes": [ { - "@id": "bts:Donor" + "@id": "bts:VendorItem" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "parentDonorId", - "sms:required": "sms:false", - "sms:requiresDependency": [ + "sms:displayName": "catalogNumber", + "sms:required": "sms:true", + "sms:validationRules": [] + }, + { + "@id": "bts:catalogNumberURL", + "@type": "rdf:Property", + "rdfs:comment": "The url linking to the resource on the vendor's website.", + "rdfs:label": "catalogNumberURL", + "schema:domainIncludes": [ { - "@id": "bts:donorId" + "@id": "bts:VendorItem" } ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "catalogNumberURL", + "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:species", - "@type": "rdf:Property", - "rdfs:comment": "The species of the individual the resource was derived from.", - "rdfs:label": "species", - "schema:domainIncludes": [ + "@id": "bts:Vendor", + "@type": "rdfs:Class", + "rdfs:comment": "A person or compnay offering the resource for sale.", + "rdfs:label": "Vendor", + "rdfs:subClassOf": [ { - "@id": "bts:Donor" + "@id": "bts:Thing" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "schema:rangeIncludes": [ - { - "@id": "bts:Homosapiens" - }, - { - "@id": "bts:Musmusculus" - }, - { - "@id": "bts:Musmusculus(humanized)" - }, - { - "@id": "bts:Rattusnorvegicus" - }, - { - "@id": "bts:Drosophilamelanogaster" - }, - { - "@id": "bts:Rhesusmacaque" - }, - { - "@id": "bts:Pantroglodytes" - }, - { - "@id": "bts:Gallusgallus" - }, + "sms:displayName": "vendor", + "sms:required": "sms:false", + "sms:requiresDependency": [ { - "@id": "bts:Susscrofa" + "@id": "bts:Component" }, { - "@id": "bts:Oryctolaguscuniculus" + "@id": "bts:vendorId" }, { - "@id": "bts:Daniorerio" + "@id": "bts:vendorName" }, { - "@id": "bts:Escherichiacoli" + "@id": "bts:vendorUrl" } ], - "sms:displayName": "species", - "sms:required": "sms:true", "sms:validationRules": [] }, { - "@id": "bts:sex", + "@id": "bts:vendorName", "@type": "rdf:Property", - "rdfs:comment": "The sex of the indiviudal from which the resource was derived from.", - "rdfs:label": "sex", + "rdfs:comment": "The name of the vendor.", + "rdfs:label": "vendorName", "schema:domainIncludes": [ { - "@id": "bts:Donor" + "@id": "bts:Vendor" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "schema:rangeIncludes": [ - { - "@id": "bts:Male" - }, - { - "@id": "bts:Female" - }, - { - "@id": "bts:Unknown" - } - ], - "sms:displayName": "sex", + "sms:displayName": "vendorName", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:age", + "@id": "bts:vendorUrl", "@type": "rdf:Property", - "rdfs:comment": "That age of the individual from which the resource was derived from.", - "rdfs:label": "age", + "rdfs:comment": "The vendor website url associated with the resource.", + "rdfs:label": "vendorUrl", "schema:domainIncludes": [ { - "@id": "bts:Donor" + "@id": "bts:Vendor" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "age", + "sms:displayName": "vendorUrl", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:race", + "@id": "bts:biobankName", "@type": "rdf:Property", - "rdfs:comment": "The ethnicity of the individual the resource was derived from.", - "rdfs:label": "race", + "rdfs:comment": "The name of the biobank.", + "rdfs:label": "biobankName", "schema:domainIncludes": [ { - "@id": "bts:Donor" + "@id": "bts:BiobankDetails" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "race", - "sms:required": "sms:false", + "sms:displayName": "biobankName", + "sms:required": "sms:true", "sms:validationRules": [] }, { - "@id": "bts:CellLine", - "@type": "rdfs:Class", - "rdfs:comment": "A cell culture selected for uniformity from a cell population derived from a usually homogeneous tissue source (such as an organ).", - "rdfs:label": "CellLine", - "rdfs:subClassOf": [ + "@id": "bts:biobankURL", + "@type": "rdf:Property", + "rdfs:comment": "A URL for the biobank landing page.", + "rdfs:label": "biobankURL", + "schema:domainIncludes": [ { - "@id": "bts:CellLine" + "@id": "bts:BiobankDetails" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "cellLine", - "sms:required": "sms:false", + "sms:displayName": "biobankURL", + "sms:required": "sms:true", "sms:validationRules": [] }, { - "@id": "bts:cellLineId", + "@id": "bts:specimenType", "@type": "rdf:Property", - "rdfs:comment": "A unique identifier for the cell line.", - "rdfs:label": "cellLineId", + "rdfs:comment": "The types of specimens that are banked.", + "rdfs:label": "specimenType", "schema:domainIncludes": [ { - "@id": "bts:Resource" + "@id": "bts:BiobankDetails" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "schema:rangeIncludes": [ + { + "@id": "bts:Humantissue" }, { - "@id": "bts:CellLine" + "@id": "bts:Xenografttumors" }, { - "@id": "bts:Mutation" + "@id": "bts:Celllines" } ], - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "sms:displayName": "cellLineId", + "sms:displayName": "specimenType", "sms:required": "sms:true", - "sms:validationRules": [] + "sms:validationRules": [ + "list like" + ] }, { - "@id": "bts:organ", + "@id": "bts:specimenTissueType", "@type": "rdf:Property", - "rdfs:comment": "The organ the cell line is derived from.", - "rdfs:label": "organ", + "rdfs:comment": "The types of tissues that are banked.", + "rdfs:label": "specimenTissueType", "schema:domainIncludes": [ { - "@id": "bts:CellLine" + "@id": "bts:BiobankDetails" } ], "schema:isPartOf": { @@ -4937,66 +3405,38 @@ "@id": "bts:Blood" }, { - "@id": "bts:Bonemarrow" - }, - { - "@id": "bts:Brain" - }, - { - "@id": "bts:Breast" - }, - { - "@id": "bts:Bursaoffabricius" - }, - { - "@id": "bts:Colon" - }, - { - "@id": "bts:Kidney" - }, - { - "@id": "bts:Lung" - }, - { - "@id": "bts:Lymphnode" - }, - { - "@id": "bts:Mammarygland" - }, - { - "@id": "bts:Nerves" - }, - { - "@id": "bts:Nose" + "@id": "bts:Tumor" }, { - "@id": "bts:Ovary" + "@id": "bts:CerebrospinalFluid" }, { - "@id": "bts:Pancreas" + "@id": "bts:Nerve" }, { - "@id": "bts:Prostate" + "@id": "bts:Skin" }, { - "@id": "bts:Skin" + "@id": "bts:Bone" }, { - "@id": "bts:Spleen" + "@id": "bts:Brain" } ], - "sms:displayName": "organ", - "sms:required": "sms:false", - "sms:validationRules": [] + "sms:displayName": "specimenTissueType", + "sms:required": "sms:true", + "sms:validationRules": [ + "list like" + ] }, { - "@id": "bts:tissue", + "@id": "bts:tumorType", "@type": "rdf:Property", - "rdfs:comment": "The tissue the cell line is derived from.", - "rdfs:label": "tissue", + "rdfs:comment": "The types of tumors that are banked, if applicable.", + "rdfs:label": "tumorType", "schema:domainIncludes": [ { - "@id": "bts:CellLine" + "@id": "bts:BiobankDetails" } ], "schema:isPartOf": { @@ -5004,69 +3444,92 @@ }, "schema:rangeIncludes": [ { - "@id": "bts:Blood" + "@id": "bts:Cutaneousneurofibroma" }, { - "@id": "bts:Bonemarrow" + "@id": "bts:Plexiformneurofibroma" }, { - "@id": "bts:Buccalmucosa" + "@id": "bts:Atypicalneurofibroma" }, { - "@id": "bts:Buffycoat" + "@id": "bts:Schwannoma" }, { - "@id": "bts:Cerebralcortex" + "@id": "bts:Meningioma" }, { - "@id": "bts:Dorsalrootganglion" + "@id": "bts:Malignantperipheralnervesheathtumor" }, { - "@id": "bts:Embryonictissue" + "@id": "bts:Lowgradeglioma" }, { - "@id": "bts:Meninges" + "@id": "bts:Highgradeglioma" }, { - "@id": "bts:Nervetissue" + "@id": "bts:Pheochromocytoma" }, { - "@id": "bts:Opticnerve" + "@id": "bts:Opticnerveglioma" }, { - "@id": "bts:Plasma" + "@id": "bts:NeurofibromaNOS" }, { - "@id": "bts:Primarytumor" + "@id": "bts:Diffuseinfiltratingneurofibroma" }, { - "@id": "bts:Sciaticnerve" + "@id": "bts:BrainNOS" }, { - "@id": "bts:Serum" - }, + "@id": "bts:Other" + } + ], + "sms:displayName": "tumorType", + "sms:required": "sms:true", + "sms:validationRules": [ + "list like" + ] + }, + { + "@id": "bts:diseaseType", + "@type": "rdf:Property", + "rdfs:comment": "The diseases of the banked specimens, if applicable.", + "rdfs:label": "diseaseType", + "schema:domainIncludes": [ { - "@id": "bts:Splenocyte" + "@id": "bts:BiobankDetails" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "schema:rangeIncludes": [ + { + "@id": "bts:Neurofibromatosistype1" }, { - "@id": "bts:Unspecified" + "@id": "bts:Neurofibromatosistype2" }, { - "@id": "bts:Wholebrain" + "@id": "bts:Schwannomatosis" } ], - "sms:displayName": "tissue", - "sms:required": "sms:false", - "sms:validationRules": [] + "sms:displayName": "diseaseType", + "sms:required": "sms:true", + "sms:validationRules": [ + "list like" + ] }, { - "@id": "bts:cellLineCategory", + "@id": "bts:specimenPreparationMethod", "@type": "rdf:Property", - "rdfs:comment": "The category to which the cell line belongs.", - "rdfs:label": "cellLineCategory", + "rdfs:comment": "The preservation methods used by the biobank.", + "rdfs:label": "specimenPreparationMethod", "schema:domainIncludes": [ { - "@id": "bts:CellLine" + "@id": "bts:BiobankDetails" } ], "schema:isPartOf": { @@ -5074,958 +3537,796 @@ }, "schema:rangeIncludes": [ { - "@id": "bts:Cancercellline" + "@id": "bts:Freshcollected" }, { - "@id": "bts:Conditionallyimmortalizedcellline" + "@id": "bts:Flashfrozen" }, { - "@id": "bts:Embryonicstemcell" + "@id": "bts:FFPE" }, { - "@id": "bts:Factor-dependentcellline" + "@id": "bts:Cryopreserved" }, { - "@id": "bts:Finitecellline" + "@id": "bts:OCT" }, { - "@id": "bts:Hybridoma" + "@id": "bts:RNAlater" }, { - "@id": "bts:Inducedpluripotentstemcell" + "@id": "bts:Formalin-fixed" }, { - "@id": "bts:Somaticstemcell" + "@id": "bts:Ethanol" + } + ], + "sms:displayName": "specimenPreparationMethod", + "sms:required": "sms:true", + "sms:validationRules": [ + "list like" + ] + }, + { + "@id": "bts:specimenFormat", + "@type": "rdf:Property", + "rdfs:comment": "How the specimens have been processed in preparation for distribution.", + "rdfs:label": "specimenFormat", + "schema:domainIncludes": [ + { + "@id": "bts:BiobankDetails" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "schema:rangeIncludes": [ + { + "@id": "bts:Wholetumor" }, { - "@id": "bts:Spontaneouslyimmortalizedcellline" + "@id": "bts:Slide" }, { - "@id": "bts:Stromalcellline" + "@id": "bts:Cells" }, { - "@id": "bts:Telomeraseimmortalizedcellline" + "@id": "bts:Wholecelllysate" }, { - "@id": "bts:Transformedcellline" + "@id": "bts:DNA" }, { - "@id": "bts:Undefinedcelllinetype" + "@id": "bts:RNA" } ], - "sms:displayName": "cellLineCategory", - "sms:required": "sms:false", - "sms:validationRules": [] + "sms:displayName": "specimenFormat", + "sms:required": "sms:true", + "sms:validationRules": [ + "list like" + ] }, { - "@id": "bts:originYear", - "@type": "rdf:Property", - "rdfs:comment": "The year the cell line orginated.", - "rdfs:label": "originYear", - "schema:domainIncludes": [ + "@id": "bts:Humantissue", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Humantissue", + "rdfs:subClassOf": [ { - "@id": "bts:CellLine" + "@id": "bts:specimenType" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "originYear", + "sms:displayName": "human tissue", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:strProfile", - "@type": "rdf:Property", - "rdfs:comment": "Short tandem repeat profile information.", - "rdfs:label": "strProfile", - "schema:domainIncludes": [ + "@id": "bts:Xenografttumors", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Xenografttumors", + "rdfs:subClassOf": [ { - "@id": "bts:CellLine" + "@id": "bts:specimenType" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "strProfile", + "sms:displayName": "xenograft tumors", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:populationDoublingTime", - "@type": "rdf:Property", - "rdfs:comment": "Time for cell line to double", - "rdfs:label": "populationDoublingTime", - "schema:domainIncludes": [ + "@id": "bts:Celllines", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Celllines", + "rdfs:subClassOf": [ { - "@id": "bts:CellLine" + "@id": "bts:specimenType" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "populationDoublingTime", + "sms:displayName": "cell lines", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:resistance", - "@type": "rdf:Property", - "rdfs:comment": "List of compounds if a cell line has been selected for.", - "rdfs:label": "resistance", - "schema:domainIncludes": [ + "@id": "bts:Blood", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Blood", + "rdfs:subClassOf": [ { - "@id": "bts:CellLine" + "@id": "bts:specimenTissueType" + }, + { + "@id": "bts:tissue" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "resistance", + "sms:displayName": "Blood", "sms:required": "sms:false", - "sms:validationRules": [ - "list" - ] + "sms:validationRules": [] }, { - "@id": "bts:contaminatedMisidentified", - "@type": "rdf:Property", - "rdfs:comment": "If a cell line has been contaminated or misidentified", - "rdfs:label": "contaminatedMisidentified", - "schema:domainIncludes": [ + "@id": "bts:Tumor", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Tumor", + "rdfs:subClassOf": [ { - "@id": "bts:CellLine" + "@id": "bts:specimenTissueType" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "contaminatedMisidentified", + "sms:displayName": "Tumor", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:cellLineGeneticDisorder", - "@type": "rdf:Property", - "rdfs:comment": "Genetic diseases are diseases in which inherited genes predispose to increased risk. The genetic disorders associated with cancer often result from an alteration or mutation in a single gene. The diseases range from rare dominant cancer family syndrome to familial tendencies in which low-penetrance genes may interact with other genes or environmental factors to induce cancer. Research may involve clinical, epidemiologic, and laboratory studies of persons, families, and populations at high risk of these disorders. [ NCI ]", - "rdfs:label": "cellLineGeneticDisorder", - "schema:domainIncludes": [ + "@id": "bts:CerebrospinalFluid", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "CerebrospinalFluid", + "rdfs:subClassOf": [ { - "@id": "bts:CellLine" + "@id": "bts:specimenTissueType" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "schema:rangeIncludes": [ - { - "@id": "bts:Neurofibromatosistype1" - }, - { - "@id": "bts:Neurofibromatosistype2" - }, - { - "@id": "bts:Schwannomatosis" - }, + "sms:displayName": "Cerebrospinal Fluid", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:Nerve", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Nerve", + "rdfs:subClassOf": [ { - "@id": "bts:Noknowndisease" + "@id": "bts:specimenTissueType" } ], - "sms:displayName": "cellLineGeneticDisorder", + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "Nerve", "sms:required": "sms:false", - "sms:validationRules": [ - "list" - ] + "sms:validationRules": [] }, { - "@id": "bts:cellLineManifestation", - "@type": "rdf:Property", - "rdfs:comment": "Manifestations/symptoms that this resource is used to model (e.g. tumor type, behavioral phenotype, etc.)", - "rdfs:label": "cellLineManifestation", - "schema:domainIncludes": [ + "@id": "bts:Skin", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Skin", + "rdfs:subClassOf": [ { - "@id": "bts:CellLine" + "@id": "bts:specimenTissueType" + }, + { + "@id": "bts:organ" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "cellLineManifestation", + "sms:displayName": "Skin", "sms:required": "sms:false", - "sms:validationRules": [ - "list" - ] + "sms:validationRules": [] }, { - "@id": "bts:MutationDetails", + "@id": "bts:Bone", "@type": "rdfs:Class", - "rdfs:comment": "The changing of the structure of a gene, resulting in a variant form that may be transmitted to subsequent generations", - "rdfs:label": "MutationDetails", + "rdfs:comment": "TBD", + "rdfs:label": "Bone", "rdfs:subClassOf": [ { - "@id": "bts:MutationDetails" + "@id": "bts:specimenTissueType" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "mutationDetails", + "sms:displayName": "Bone", "sms:required": "sms:false", - "sms:requiresDependency": [ - { - "@id": "bts:Component" - }, - { - "@id": "bts:mutationDetailsId" - }, - { - "@id": "bts:externalMutationID" - }, - { - "@id": "bts:alleleType" - }, - { - "@id": "bts:mutationType" - }, - { - "@id": "bts:mutationMethod" - }, - { - "@id": "bts:affectedGeneSymbol" - }, - { - "@id": "bts:affectedGeneName" - }, - { - "@id": "bts:sequenceVariation" - }, - { - "@id": "bts:proteinVariation" - }, - { - "@id": "bts:animalModelMutation" - }, + "sms:validationRules": [] + }, + { + "@id": "bts:Brain", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Brain", + "rdfs:subClassOf": [ { - "@id": "bts:humanClinVarMutation" + "@id": "bts:organ" }, { - "@id": "bts:chromosome" + "@id": "bts:specimenTissueType" } ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "Brain", + "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:mutationDetailsId", - "@type": "rdf:Property", - "rdfs:comment": "A unique identifier for mutation.", - "rdfs:label": "mutationDetailsId", - "schema:domainIncludes": [ - { - "@id": "bts:MutationDetails" - }, + "@id": "bts:Cutaneousneurofibroma", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Cutaneousneurofibroma", + "rdfs:subClassOf": [ { - "@id": "bts:Mutation" + "@id": "bts:tumorType" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "mutationDetailsId", + "sms:displayName": "cutaneous neurofibroma", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:externalMutationID", - "@type": "rdf:Property", - "rdfs:comment": "An identifier from an organism database such as MGI or other curated variant resource, if available. ", - "rdfs:label": "externalMutationID", - "schema:domainIncludes": [ + "@id": "bts:Plexiformneurofibroma", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Plexiformneurofibroma", + "rdfs:subClassOf": [ { - "@id": "bts:MutationDetails" + "@id": "bts:tumorType" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "externalMutationID", + "sms:displayName": "plexiform neurofibroma", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:mutationType", - "@type": "rdf:Property", - "rdfs:comment": "The type of the mutation, vocabulary aligned with MGI mutation types. ", - "rdfs:label": "mutationType", - "schema:domainIncludes": [ + "@id": "bts:Atypicalneurofibroma", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Atypicalneurofibroma", + "rdfs:subClassOf": [ { - "@id": "bts:MutationDetails" + "@id": "bts:tumorType" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "schema:rangeIncludes": [ - { - "@id": "bts:Disruptioncausedbyinsertionofvector" - }, - { - "@id": "bts:Duplication" - }, - { - "@id": "bts:Insertion" - }, - { - "@id": "bts:Insertionofgenetrapvector" - }, - { - "@id": "bts:Intergenicdeletion" - }, - { - "@id": "bts:Intragenicdeletion" - }, - { - "@id": "bts:Inversion" - }, - { - "@id": "bts:Lossofheterozygosity(unspecifiedmechanism)" - }, - { - "@id": "bts:NotApplicable" - }, - { - "@id": "bts:NotSpecified" - }, - { - "@id": "bts:Nucleotiderepeatexpansion" - }, - { - "@id": "bts:Nucleotidesubstitutions" - }, - { - "@id": "bts:Other" - }, - { - "@id": "bts:Singlepointmutation" - }, - { - "@id": "bts:Translocation" - }, - { - "@id": "bts:Transposoninsertion" - }, - { - "@id": "bts:Undefined" - }, - { - "@id": "bts:Viralinsertion" - } - ], - "sms:displayName": "mutationType", + "sms:displayName": "atypical neurofibroma", "sms:required": "sms:false", - "sms:validationRules": [ - "list" - ] + "sms:validationRules": [] }, { - "@id": "bts:mutationMethod", - "@type": "rdf:Property", - "rdfs:comment": "The method used to alter the resource, vocabulary aligned with and expanded upon MGI allele origin types. ", - "rdfs:label": "mutationMethod", - "schema:domainIncludes": [ + "@id": "bts:Schwannoma", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Schwannoma", + "rdfs:subClassOf": [ { - "@id": "bts:MutationDetails" + "@id": "bts:tumorType" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "schema:rangeIncludes": [ - { - "@id": "bts:Chemicallyinduced(ENU)" - }, - { - "@id": "bts:Chemicallyinduced(other)" - }, - { - "@id": "bts:Chemicallyandradiationinduced" - }, - { - "@id": "bts:Endonuclease-mediated(CRISPR)" - }, - { - "@id": "bts:Endonuclease-mediated(TALEN)" - }, - { - "@id": "bts:Genetrapped" - }, - { - "@id": "bts:QTL" - }, - { - "@id": "bts:Radiationinduced" - }, - { - "@id": "bts:Spontaneous" - }, - { - "@id": "bts:Targeted" - }, - { - "@id": "bts:Transgenic" - }, - { - "@id": "bts:Transposoninduced" - } - ], - "sms:displayName": "mutationMethod", + "sms:displayName": "schwannoma", "sms:required": "sms:false", - "sms:validationRules": [ - "list" - ] + "sms:validationRules": [] }, { - "@id": "bts:alleleType", - "@type": "rdf:Property", - "rdfs:comment": "The type of genetic alteration of the resource, vocabulary aligned with MGI allele subtypes. ", - "rdfs:label": "alleleType", - "schema:domainIncludes": [ + "@id": "bts:Meningioma", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Meningioma", + "rdfs:subClassOf": [ { - "@id": "bts:MutationDetails" + "@id": "bts:tumorType" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "schema:rangeIncludes": [ - { - "@id": "bts:Conditionalready" - }, - { - "@id": "bts:Constitutivelyactive" - }, - { - "@id": "bts:Dominantnegative" - }, - { - "@id": "bts:Humanizedsequence" - }, - { - "@id": "bts:Hypomorph" - }, - { - "@id": "bts:Inducible" - }, - { - "@id": "bts:Insertedexpressedsequence" - }, - { - "@id": "bts:Knockdown" - }, - { - "@id": "bts:Modifiedisoform(s)" - }, - { - "@id": "bts:Nofunctionalchange" - }, - { - "@id": "bts:Null/knockout" - }, - { - "@id": "bts:Recombinase" - }, - { - "@id": "bts:Reporter" - }, - { - "@id": "bts:RMCE-Ready" - }, - { - "@id": "bts:Transactivator" - }, - { - "@id": "bts:Transposase" - }, + "sms:displayName": "meningioma", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:Malignantperipheralnervesheathtumor", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Malignantperipheralnervesheathtumor", + "rdfs:subClassOf": [ { - "@id": "bts:Transposonconcatemer" + "@id": "bts:tumorType" } ], - "sms:displayName": "alleleType", + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "malignant peripheral nerve sheath tumor", "sms:required": "sms:false", - "sms:validationRules": [ - "list" - ] + "sms:validationRules": [] }, { - "@id": "bts:affectedGeneSymbol", - "@type": "rdf:Property", - "rdfs:comment": "The gene symbol for the mutated gene. 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(e.g. embryo, sperm, live)", - "rdfs:label": "animalState", - "schema:domainIncludes": [ + "@id": "bts:RNAlater", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "RNAlater", + "rdfs:subClassOf": [ { - "@id": "bts:AnimalModel" + "@id": "bts:specimenPreparationMethod" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "animalState", + "sms:displayName": "RNA later", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:backgroundStrain", - "@type": "rdf:Property", - "rdfs:comment": "An assigned name that describes the genetic make-up (all its alleles at all loci) except the mutated gene of interest and a very small amount of other genetic material, generally from one or two other strains. Correct strain nomenclature indicates what a mutant strain’s background is.", - "rdfs:label": "backgroundStrain", - "schema:domainIncludes": [ + "@id": "bts:Formalin-fixed", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Formalin-fixed", + "rdfs:subClassOf": [ { - "@id": "bts:AnimalModel" + "@id": "bts:specimenPreparationMethod" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "backgroundStrain", + "sms:displayName": "Formalin-fixed", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:backgroundSubstrain", - "@type": "rdf:Property", - "rdfs:comment": "The substrain is a particular variety of a strain. For example, a C57BL/6 mice may have a substrain of C57BL/6J, C57BL/6Tac, or another substrain. 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See http://www.informatics.jax.org/mgihome/nomen/strains.shtml for nomenclature information.", - "rdfs:label": "strainNomenclature", - "schema:domainIncludes": [ + "@id": "bts:Wholetumor", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "Wholetumor", + "rdfs:subClassOf": [ { - "@id": "bts:AnimalModel" + "@id": "bts:specimenFormat" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "strainNomenclature", + "sms:displayName": "whole tumor", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:generation", - "@type": "rdf:Property", - "rdfs:comment": "The generation of the animal model. 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The diseases range from rare dominant cancer family syndrome to familial tendencies in which low-penetrance genes may interact with other genes or environmental factors to induce cancer. Research may involve clinical, epidemiologic, and laboratory studies of persons, families, and populations at high risk of these disorders. [ NCI ]", - "rdfs:label": "animalModelGeneticDisorder", - "schema:domainIncludes": [ + "@id": "bts:DNA", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "DNA", + "rdfs:subClassOf": [ { - "@id": "bts:AnimalModel" + "@id": "bts:specimenFormat" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "schema:rangeIncludes": [ - { - "@id": "bts:Neurofibromatosistype1" - }, - { - "@id": "bts:Neurofibromatosistype2" - }, - { - "@id": "bts:Schwannomatosis" - }, - { - "@id": "bts:Noknowndisease" - } - ], - "sms:displayName": "animalModelGeneticDisorder", - "sms:required": "sms:true", - "sms:validationRules": [ - "list" - ] + "sms:displayName": "DNA", + "sms:required": "sms:false", + "sms:validationRules": [] }, { - "@id": "bts:animalModelOfManifestation", - "@type": "rdf:Property", - "rdfs:comment": "Manifestations/symptoms that this resource is used to model (e.g. tumor type, behavioral phenotype, etc.) ", - "rdfs:label": "animalModelOfManifestation", - "schema:domainIncludes": [ + "@id": "bts:RNA", + "@type": "rdfs:Class", + "rdfs:comment": "TBD", + "rdfs:label": "RNA", + "rdfs:subClassOf": [ { - 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"@id": "bts:developmentId" + "@id": "bts:observationId" }, { "@id": "bts:resourceId" }, - { - "@id": "bts:investigatorId" - }, { "@id": "bts:publicationId" }, { - "@id": "bts:funderId" - } - ], - "sms:validationRules": [] - }, - { - "@id": "bts:developmentId", - "@type": "rdf:Property", - "rdfs:comment": "A unique identifier for the development of the resource.", - "rdfs:label": "developmentId", - "schema:domainIncludes": [ - { - "@id": "bts:Development" - } - ], - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "sms:displayName": "developmentId", - "sms:required": "sms:true", - "sms:validationRules": [] - }, - { - "@id": "bts:Funder", - "@type": "rdfs:Class", - "rdfs:comment": "A person or organization that provides money for a particular resource.", - "rdfs:label": "Funder", - "rdfs:subClassOf": [ - { - "@id": "bts:Funder" - } - ], - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "sms:displayName": "funder", - "sms:required": "sms:false", - "sms:requiresDependency": [ - { - "@id": "bts:Component" - }, - { - "@id": "bts:funderId" - }, - { - "@id": "bts:funderName" - } - ], - "sms:validationRules": [] - }, - { - "@id": "bts:funderId", - "@type": "rdf:Property", - "rdfs:comment": "A unique identifier for the funder of the resource.", - "rdfs:label": "funderId", - "schema:domainIncludes": [ - { - "@id": "bts:Development" - }, - { - "@id": "bts:Funder" - } - ], - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "sms:displayName": "funderId", - "sms:required": "sms:false", - "sms:validationRules": [] - }, - { - "@id": "bts:funderName", - "@type": "rdf:Property", - "rdfs:comment": "The name of the person or agency that funded the development of the resource.", - "rdfs:label": "funderName", - "schema:domainIncludes": [ - { - "@id": "bts:Funder" - } - ], - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "sms:displayName": "funderName", - "sms:required": "sms:false", - "sms:validationRules": [] - }, - { - "@id": "bts:Investigator", - "@type": "rdfs:Class", - "rdfs:comment": "A person who carries out a formal inquiry or investigation into the development of the resource.", - "rdfs:label": "Investigator", - "rdfs:subClassOf": [ + "@id": "bts:observationSubmitterName" + }, { - "@id": "bts:Investigator" - } - ], - "schema:isPartOf": { - "@id": "http://schema.biothings.io" - }, - "sms:displayName": "investigator", - "sms:required": "sms:false", - "sms:requiresDependency": [ + "@id": "bts:synapseId" + }, { - "@id": "bts:Component" + "@id": "bts:observationText" }, { - "@id": "bts:investigatorId" + "@id": "bts:observationType" }, { - "@id": "bts:orcid" + "@id": "bts:observationPhase" }, { - "@id": "bts:investigatorName" + "@id": "bts:observationTime" }, { - "@id": "bts:institution" + "@id": "bts:observationTimeUnits" }, { - "@id": "bts:investigatorWebsite" + "@id": "bts:reliabilityRating" }, { - "@id": "bts:investigatorSynapseId" + "@id": "bts:easeOfUseRating" + }, + { + "@id": "bts:observationLink" } ], "sms:validationRules": [] }, { - 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", - "rdfs:label": "doi", + "rdfs:comment": "A link/reference related to the observation being recorded. 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(e.g. 13)", + "rdfs:label": "generation", + "schema:domainIncludes": [ { - "@id": "bts:MutationDetails" + "@id": "bts:AnimalModelDetails" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "Endonuclease-mediated (CRISPR)", + "sms:displayName": "generation", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:Endonuclease-mediated(TALEN)", - "@type": "rdfs:Class", - "rdfs:comment": "TBD", - "rdfs:label": "Endonuclease-mediated(TALEN)", - "rdfs:subClassOf": [ + "@id": "bts:transplantationType", + "@type": "rdf:Property", + "rdfs:comment": "Type of transplantation involved in the experiment, derived from MESH", + "rdfs:label": "transplantationType", + "schema:domainIncludes": [ { - "@id": "bts:MutationDetails" + "@id": "bts:AnimalModelDetails" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "Endonuclease-mediated (TALEN)", + "schema:rangeIncludes": [ + { + "@id": "bts:Allograft" + }, + { + "@id": "bts:Xenograft" + }, + { + "@id": "bts:Autograft" + }, + { + "@id": "bts:Isograft" + } + ], + "sms:displayName": "transplantationType", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:Genetrapped", - "@type": "rdfs:Class", - "rdfs:comment": "TBD", - "rdfs:label": "Genetrapped", - "rdfs:subClassOf": [ + "@id": "bts:animalModelGeneticDisorder", + "@type": "rdf:Property", + "rdfs:comment": "Genetic diseases are diseases in which inherited genes predispose to increased risk. The genetic disorders associated with cancer often result from an alteration or mutation in a single gene. The diseases range from rare dominant cancer family syndrome to familial tendencies in which low-penetrance genes may interact with other genes or environmental factors to induce cancer. Research may involve clinical, epidemiologic, and laboratory studies of persons, families, and populations at high risk of these disorders. [ NCI ]", + "rdfs:label": "animalModelGeneticDisorder", + "schema:domainIncludes": [ { - "@id": "bts:MutationDetails" + "@id": "bts:AnimalModelDetails" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "Gene trapped", - "sms:required": "sms:false", - "sms:validationRules": [] + "schema:rangeIncludes": [ + { + "@id": "bts:Neurofibromatosistype1" + }, + { + "@id": "bts:Neurofibromatosistype2" + }, + { + "@id": "bts:Schwannomatosis" + }, + { + "@id": "bts:Noknowngeneticdisorder" + } + ], + "sms:displayName": "animalModelGeneticDisorder", + "sms:required": "sms:true", + "sms:validationRules": [ + "list like" + ] }, { - "@id": "bts:QTL", - "@type": "rdfs:Class", - "rdfs:comment": "TBD", - "rdfs:label": "QTL", - "rdfs:subClassOf": [ + "@id": "bts:animalModelOfManifestation", + "@type": "rdf:Property", + "rdfs:comment": "Manifestations/symptoms that this resource is used to model (e.g. tumor type, behavioral phenotype, etc.)", + "rdfs:label": "animalModelOfManifestation", + "schema:domainIncludes": [ { - "@id": "bts:MutationDetails" + "@id": "bts:AnimalModelDetails" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "QTL", - "sms:required": "sms:false", - "sms:validationRules": [] + "sms:displayName": "animalModelOfManifestation", + "sms:required": "sms:true", + "sms:validationRules": [ + "list like" + ] }, { - "@id": "bts:Radiationinduced", + "@id": "bts:Allograft", "@type": "rdfs:Class", "rdfs:comment": "TBD", - "rdfs:label": "Radiationinduced", + "rdfs:label": "Allograft", "rdfs:subClassOf": [ { - "@id": "bts:MutationDetails" + "@id": "bts:transplantationType" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "Radiation induced", + "sms:displayName": "allograft", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:Spontaneous", + "@id": "bts:Xenograft", "@type": "rdfs:Class", "rdfs:comment": "TBD", - "rdfs:label": "Spontaneous", + "rdfs:label": "Xenograft", "rdfs:subClassOf": [ { - "@id": "bts:MutationDetails" + "@id": "bts:transplantationType" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "Spontaneous", + "sms:displayName": "xenograft", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:Targeted", + "@id": "bts:Autograft", "@type": "rdfs:Class", "rdfs:comment": "TBD", - "rdfs:label": "Targeted", + "rdfs:label": "Autograft", "rdfs:subClassOf": [ { - "@id": "bts:MutationDetails" + "@id": "bts:transplantationType" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "Targeted", + "sms:displayName": "autograft", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:Transgenic", + "@id": "bts:Isograft", "@type": "rdfs:Class", "rdfs:comment": "TBD", - "rdfs:label": "Transgenic", + "rdfs:label": "Isograft", "rdfs:subClassOf": [ { - "@id": "bts:MutationDetails" + "@id": "bts:transplantationType" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "Transgenic", + "sms:displayName": "isograft", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:Transposoninduced", + "@id": "bts:Development", "@type": "rdfs:Class", - "rdfs:comment": "TBD", - "rdfs:label": "Transposoninduced", + "rdfs:comment": "resourceId, investigatorId, publicationId, funderId (intermediary table)", + "rdfs:label": "Development", "rdfs:subClassOf": [ { - "@id": "bts:MutationDetails" + "@id": "bts:Thing" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "Transposon induced", + "sms:displayName": "development", "sms:required": "sms:false", + "sms:requiresComponent": [ + { + "@id": "bts:Resource" + }, + { + "@id": "bts:Investigator" + }, + { + "@id": "bts:Publication" + }, + { + "@id": "bts:Funder" + } + ], + "sms:requiresDependency": [ + { + "@id": "bts:Component" + }, + { + "@id": "bts:developmentId" + }, + { + "@id": "bts:resourceId" + }, + { + "@id": "bts:investigatorId" + }, + { + "@id": "bts:publicationId" + }, + { + "@id": "bts:funderId" + } + ], "sms:validationRules": [] }, { - "@id": "bts:Conditionalready", - "@type": "rdfs:Class", - "rdfs:comment": "TBD", - "rdfs:label": "Conditionalready", - "rdfs:subClassOf": [ + "@id": "bts:developmentId", + "@type": "rdf:Property", + "rdfs:comment": "A unique identifier for the development of the resource.", + "rdfs:label": "developmentId", + "schema:domainIncludes": [ { - "@id": "bts:MutationDetails" + "@id": "bts:Development" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "Conditional ready", - "sms:required": "sms:false", + "sms:displayName": "developmentId", + "sms:required": "sms:true", "sms:validationRules": [] }, { - "@id": "bts:Constitutivelyactive", - "@type": "rdfs:Class", - "rdfs:comment": "TBD", - "rdfs:label": "Constitutivelyactive", - "rdfs:subClassOf": [ + "@id": "bts:investigatorId", + "@type": "rdf:Property", + "rdfs:comment": "A unique identifier for the investigator.", + "rdfs:label": "investigatorId", + "schema:domainIncludes": [ { - "@id": "bts:MutationDetails" + "@id": "bts:Development" + }, + { + "@id": "bts:Investigator" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "Constitutively active", + "sms:displayName": "investigatorId", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:Dominantnegative", - "@type": "rdfs:Class", - "rdfs:comment": "TBD", - "rdfs:label": "Dominantnegative", - "rdfs:subClassOf": [ + "@id": "bts:funderId", + "@type": "rdf:Property", + "rdfs:comment": "A unique identifier for the funder of the resource.", + "rdfs:label": "funderId", + "schema:domainIncludes": [ { - "@id": "bts:MutationDetails" + "@id": "bts:Development" + }, + { + "@id": "bts:Funder" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "Dominant negative", + "sms:displayName": "funderId", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:Humanizedsequence", + "@id": "bts:Funder", "@type": "rdfs:Class", - "rdfs:comment": "TBD", - "rdfs:label": "Humanizedsequence", + "rdfs:comment": "A person or organization that provides money for a particular resource.", + "rdfs:label": "Funder", "rdfs:subClassOf": [ { - "@id": "bts:MutationDetails" + "@id": "bts:Thing" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "Humanized sequence", + "sms:displayName": "funder", "sms:required": "sms:false", + "sms:requiresDependency": [ + { + "@id": "bts:Component" + }, + { + "@id": "bts:funderId" + }, + { + "@id": "bts:funderName" + } + ], "sms:validationRules": [] }, { - "@id": "bts:Hypomorph", - "@type": "rdfs:Class", - "rdfs:comment": "TBD", - "rdfs:label": "Hypomorph", - "rdfs:subClassOf": [ + "@id": "bts:funderName", + "@type": "rdf:Property", + "rdfs:comment": "The name of the person or agency that funded the development of the resource.", + "rdfs:label": "funderName", + "schema:domainIncludes": [ { - "@id": "bts:MutationDetails" + "@id": "bts:Funder" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "Hypomorph", + "sms:displayName": "funderName", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:Inducible", - "@type": "rdfs:Class", - "rdfs:comment": "TBD", - "rdfs:label": "Inducible", - "rdfs:subClassOf": [ + "@id": "bts:orcid", + "@type": "rdf:Property", + "rdfs:comment": "The orcidId of the investigator that developed the resource", + "rdfs:label": "orcid", + "schema:domainIncludes": [ { - "@id": "bts:MutationDetails" + "@id": "bts:Investigator" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "Inducible", + "sms:displayName": "orcid", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:Insertedexpressedsequence", - "@type": "rdfs:Class", - "rdfs:comment": "TBD", - "rdfs:label": "Insertedexpressedsequence", - "rdfs:subClassOf": [ + "@id": "bts:investigatorName", + "@type": "rdf:Property", + "rdfs:comment": "The name of the investigator responsible for devleoping the resource.", + "rdfs:label": "investigatorName", + "schema:domainIncludes": [ { - "@id": "bts:MutationDetails" + "@id": "bts:Investigator" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "Inserted expressed sequence", - "sms:required": "sms:false", + "sms:displayName": "investigatorName", + "sms:required": "sms:true", "sms:validationRules": [] }, { - "@id": "bts:Knockdown", - "@type": "rdfs:Class", - "rdfs:comment": "TBD", - "rdfs:label": "Knockdown", - "rdfs:subClassOf": [ + "@id": "bts:institution", + "@type": "rdf:Property", + "rdfs:comment": "The insitution of the investator", + "rdfs:label": "institution", + "schema:domainIncludes": [ { - "@id": "bts:MutationDetails" + "@id": "bts:Investigator" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "Knockdown", + "sms:displayName": "institution", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:Modifiedisoform(s)", - "@type": "rdfs:Class", - "rdfs:comment": "TBD", - "rdfs:label": "Modifiedisoform(s)", - "rdfs:subClassOf": [ + "@id": "bts:investigatorWebsite", + "@type": "rdf:Property", + "rdfs:comment": "The url to the investigator's laboratory website corresponding to the resource.", + "rdfs:label": "investigatorWebsite", + "schema:domainIncludes": [ { - "@id": "bts:MutationDetails" + "@id": "bts:Investigator" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "Modified isoform(s)", + "sms:displayName": "investigatorWebsite", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:Nofunctionalchange", - "@type": "rdfs:Class", - "rdfs:comment": "TBD", - "rdfs:label": "Nofunctionalchange", - "rdfs:subClassOf": [ + "@id": "bts:investigatorSynapseId", + "@type": "rdf:Property", + "rdfs:comment": "The synapse identifier for the investigator.", + "rdfs:label": "investigatorSynapseId", + "schema:domainIncludes": [ { - "@id": "bts:MutationDetails" + "@id": "bts:Investigator" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "No functional change", + "sms:displayName": "investigatorSynapseId", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:Null/knockout", - "@type": "rdfs:Class", - "rdfs:comment": "TBD", - "rdfs:label": "Null/knockout", - "rdfs:subClassOf": [ + "@id": "bts:publicationTitle", + "@type": "rdf:Property", + "rdfs:comment": "The title of the publication associated with the resource.", + "rdfs:label": "publicationTitle", + "schema:domainIncludes": [ { - "@id": "bts:MutationDetails" + "@id": "bts:Publication" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "Null/knockout", - "sms:required": "sms:false", + "sms:displayName": "publicationTitle", + "sms:required": "sms:true", "sms:validationRules": [] }, { - "@id": "bts:Recombinase", - "@type": "rdfs:Class", - "rdfs:comment": "TBD", - "rdfs:label": "Recombinase", - "rdfs:subClassOf": [ + "@id": "bts:authors", + "@type": "rdf:Property", + "rdfs:comment": "Writers of the publication.", + "rdfs:label": "authors", + "schema:domainIncludes": [ { - "@id": "bts:MutationDetails" + "@id": "bts:Publication" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "Recombinase", + "sms:displayName": "authors", "sms:required": "sms:false", - "sms:validationRules": [] + "sms:validationRules": [ + "list like" + ] }, { - "@id": "bts:Reporter", - "@type": "rdfs:Class", - "rdfs:comment": "TBD", - "rdfs:label": "Reporter", - "rdfs:subClassOf": [ + "@id": "bts:abstract", + "@type": "rdf:Property", + "rdfs:comment": "A brief, comprehensive summary of the contents of a publication.", + "rdfs:label": "abstract", + "schema:domainIncludes": [ { - "@id": "bts:MutationDetails" + "@id": "bts:Publication" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "Reporter", + "sms:displayName": "abstract", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:RMCE-Ready", - "@type": "rdfs:Class", - "rdfs:comment": "TBD", - "rdfs:label": "RMCE-Ready", - "rdfs:subClassOf": [ + "@id": "bts:journal", + "@type": "rdf:Property", + "rdfs:comment": "The name of the periodical publication in which the paper was published.", + "rdfs:label": "journal", + "schema:domainIncludes": [ { - "@id": "bts:MutationDetails" + "@id": "bts:Publication" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "RMCE-Ready", + "sms:displayName": "journal", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:Transactivator", - "@type": "rdfs:Class", - "rdfs:comment": "TBD", - "rdfs:label": "Transactivator", - "rdfs:subClassOf": [ + "@id": "bts:publicationDate", + "@type": "rdf:Property", + "rdfs:comment": "The date of the paper's publication.", + "rdfs:label": "publicationDate", + "schema:domainIncludes": [ { - "@id": "bts:MutationDetails" + "@id": "bts:Publication" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "Transactivator", + "sms:displayName": "publicationDate", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:Transposase", - "@type": "rdfs:Class", - "rdfs:comment": "TBD", - "rdfs:label": "Transposase", - "rdfs:subClassOf": [ + "@id": "bts:pmid", + "@type": "rdf:Property", + "rdfs:comment": "The PubMed Identifier associated with the publication.", + "rdfs:label": "pmid", + "schema:domainIncludes": [ { - "@id": "bts:MutationDetails" + "@id": "bts:Publication" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "Transposase", + "sms:displayName": "pmid", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:Transposonconcatemer", - "@type": "rdfs:Class", - "rdfs:comment": "TBD", - "rdfs:label": "Transposonconcatemer", - "rdfs:subClassOf": [ + "@id": "bts:doi", + "@type": "rdf:Property", + "rdfs:comment": "The digital object identifier associated with the publication in the form of https://www.doi.org/{doi} to comply with CrossRef DOI display guidelines.", + "rdfs:label": "doi", + "schema:domainIncludes": [ { - "@id": "bts:MutationDetails" + "@id": "bts:Publication" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "Transposon concatemer", + "sms:displayName": "doi", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:Allograft", - "@type": "rdfs:Class", - "rdfs:comment": "TBD", - "rdfs:label": "Allograft", - "rdfs:subClassOf": [ + "@id": "bts:citation", + "@type": "rdf:Property", + "rdfs:comment": "A merged citation for the publication, used to render citation on details pages.", + "rdfs:label": "citation", + "schema:domainIncludes": [ { - "@id": "bts:AnimalModel" + "@id": "bts:Publication" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "allograft", - "sms:required": "sms:false", + "sms:displayName": "citation", + "sms:required": "sms:true", "sms:validationRules": [] }, { - "@id": "bts:Xenograft", - "@type": "rdfs:Class", - "rdfs:comment": "TBD", - "rdfs:label": "Xenograft", - "rdfs:subClassOf": [ + "@id": "bts:publicationDateUnix", + "@type": "rdf:Property", + "rdfs:comment": "The date of the paper's publication in UNIX time", + "rdfs:label": "publicationDateUnix", + "schema:domainIncludes": [ { - "@id": "bts:AnimalModel" + "@id": "bts:Publication" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "xenograft", + "sms:displayName": "publicationDateUnix", "sms:required": "sms:false", "sms:validationRules": [] }, { - "@id": "bts:Autograft", + "@id": "bts:Usage", "@type": "rdfs:Class", - "rdfs:comment": "TBD", - "rdfs:label": "Autograft", + "rdfs:comment": "Publications referencing the resource's use.", + "rdfs:label": "Usage", "rdfs:subClassOf": [ { - "@id": "bts:AnimalModel" + "@id": "bts:Thing" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "autograft", + "sms:displayName": "usage", "sms:required": "sms:false", + "sms:requiresComponent": [ + { + "@id": "bts:Publication" + }, + { + "@id": "bts:Resource" + } + ], + "sms:requiresDependency": [ + { + "@id": "bts:Component" + }, + { + "@id": "bts:usageId" + }, + { + "@id": "bts:publicationId" + }, + { + "@id": "bts:resourceId" + } + ], "sms:validationRules": [] }, { - "@id": "bts:Isograft", - "@type": "rdfs:Class", - "rdfs:comment": "TBD", - "rdfs:label": "Isograft", - "rdfs:subClassOf": [ + "@id": "bts:usageId", + "@type": "rdf:Property", + "rdfs:comment": "A unique identifier for the usage of the resource.", + "rdfs:label": "usageId", + "schema:domainIncludes": [ { - "@id": "bts:AnimalModel" + "@id": "bts:Usage" } ], "schema:isPartOf": { "@id": "http://schema.biothings.io" }, - "sms:displayName": "isograft", - "sms:required": "sms:false", + "sms:displayName": "usageId", + "sms:required": "sms:true", "sms:validationRules": [] } ], diff --git a/nf_research_tools.rdb.model.csv b/nf_research_tools.rdb.model.csv index 9f9a2d0..84ea37f 100644 --- a/nf_research_tools.rdb.model.csv +++ b/nf_research_tools.rdb.model.csv @@ -1,68 +1,74 @@ Attribute,Description,Valid Values,DependsOn,Required,Source,Parent,Properties,DependsOn Component,Validation Rules Component,Type of submitted information.,,,TRUE,,,,, -resource,"A tool used in the research process (i.e. animal model, cell line, etc.)",,"Component, resourceId, geneticReagentId, antibodyId, cellLineId, animalModelId, rrid, resourceName, synonyms, resourceType, description, usageRequirements, howToAcquire, dateAdded, dateModified",FALSE,,,"resourceId, geneticReagentId, antibodyId, cellLineId, animalModelId, rrid, resourceName, synonyms, resourceType, description, usageRequirements, howToAcquire, dateAdded, dateModified","geneticReagent, antibody, cellLine, animalModel", +resource,"A tool used in the research process (i.e. animal model, cell line, etc.)",,"Component, resourceId, rrid, resourceName, synonyms, resourceType, description, aiSummary, usageRequirements, howToAcquire, dateAdded, dateModified",FALSE,,,"resourceId, animalModelId, antibodyId, cellLineId, geneticReagentId, biobankId, rrid, resourceName, synonyms, resourceType, description, aiSummary, usageRequirements, howToAcquire, dateAdded, dateModified","geneticReagentDetails, antibodyDetails, cellLineDetails, animalModelDetails, biobankDetails", resourceId,A unique identifier for the resource.,,,TRUE,,resource,,, rrid,"The RRID, a standard resource identifier that will facilitate interoperability with other databases, and is an increasingly-used identifier for publications https://scicrunch.org/resources if available",,,FALSE,,resource,,, resourceName,The “canonical” name of the resource,,,TRUE,,resource,,, -synonyms,Synonyms of the resource,,,FALSE,,resource,,,list +synonyms,Synonyms of the resource,,,FALSE,,resource,,,list like resourceType,"Type of resource. (e.g. animal model, antibody, plasmid, etc.)","Animal Model, Cell Line, Antibody, Genetic Reagent, Biobank",,TRUE,,resource,,, +Animal Model,,,animalModelId,,,resourceType,,, +Cell Line,,,cellLineId,,,resourceType,,, +Genetic Reagent,,,geneticReagentId,,,resourceType,,, +Antibody,,,antibodyId,,,resourceType,,, +Biobank,,,biobankId,,,resourceType,,, description,Free text description/summary/overview/purpose of the resource.,,,FALSE,,resource,,, -usageRequirements,Any known restrictions on use of the resource. ,"non-commercial use only, re-distribution not permitted, generation of germ line transmitting chimeras not permitted, creation of functional gametes not permitted, generation of interspecies chimeras not permitted, human cloning not permitted, cannot be used for treatment purposes, IRB documentation required, special licencing restrictions (see vendor for more information), unknown",,FALSE,,resource,,,list +aiSummary,A large language model-generated summary of the resource (currently generated with gpt-3.5-turbo).,,,FALSE,,resource,,, +usageRequirements,Any known restrictions on use of the resource. ,"data sharing required, non-commercial use only, re-distribution not permitted, generation of germ line transmitting chimeras not permitted, creation of functional gametes not permitted, generation of interspecies chimeras not permitted, human cloning not permitted, cannot be used for treatment purposes, IRB documentation required, special licencing restrictions (see vendor for more information), unknown",,FALSE,,resource,,,list like howToAcquire,How to acquire a particular resource. ,,,TRUE,,resource,,, dateAdded,The date that the resource was originally added.,,,TRUE,,resource,,, dateModified,The last update of the resource metadata (not including observations).,,,TRUE,,resource,,, -geneticReagent,Genetic reagents.,,"Component, geneticReagentId, insertName, insertEntrezId, gRNAshRNASequence, insertSize, insertSpecies, nTerminalTag, cTerminalTag, cloningMethod, 5primeCloningSite, 5primeSiteDestroyed, 3primeCloningSite, 3primeSiteDestroyed, promoter, 5primer, 3primer, vectorBackbone, vectorType, backboneSize, totalSize, bacterialResistance, selectableMarker, copyNumber, growthTemp, growthStrain, hazardous",FALSE,,geneticReagent,"geneticReagentId, insertName, insertEntrezId, gRNAshRNASequence, insertSize, insertSpecies, nTerminalTag, cTerminalTag, cloningMethod, 5primeCloningSite, 5primeSiteDestroyed, 3primeCloningSite, 3primeSiteDestroyed, promoter, 5primer, 3primer, vectorBackbone, vectorType, backboneSize, totalSize, bacterialResistance, selectableMarker, copyNumber, growthTemp, growthStrain, hazardous",, -geneticReagentId,A unique identifier for the reagent.,,,TRUE,,geneticReagent,,, -insertName,Name of the main gene insert in the plasmid.,,,TRUE,,geneticReagent,,, -insertEntrezId,The entrez gene id for the gene insert,,,TRUE,,geneticReagent,,, -gRNAshRNASequence,"The sequence of the gRNA or shRNA for the gene insert, if present. ",,,FALSE,,geneticReagent,,, -insertSize,"Size, in bp, of the gene insert as it is in the plasmid.",,,FALSE,,geneticReagent,,, -insertSpecies,Species of the insert,"Homo sapiens, Mus musculus, Rattus norvegicus",,TRUE,,geneticReagent,,,list -nTerminalTag,Any tags on the N terminal 5' end of the gene insert in the plasmid. Only tags that are in frame,,,FALSE,,geneticReagent,,,list -cTerminalTag,Any tags on the C terminal 3' end of the gene insert in the plasmid. Only tags that are in frame,,,FALSE,,geneticReagent,,,list -cloningMethod,"How the vector was constructed. (e.g. restriction enzyme, TOPO cloning, etc.)","Restriction Enzyme, TOPO cloning, Gateway Cloning, Ligation Independent Cloning, Gibson Cloning, Unknown",,FALSE,,geneticReagent,,, -5primeCloningSite,"If Restriction Enzyme was selected as the cloning method, specifies what enzyme was used on the 5' (N-terminal) end of the insert",,cloningMethod,FALSE,,geneticReagent,,, -5primeSiteDestroyed,"If 5' site was destroyed during cloning. (e.g. yes, no, unknown).","Yes, No, Unknown",,FALSE,,geneticReagent,,, -3primeCloningSite,"If Restriction Enzyme was selected as the cloning method, specifies what enzyme was used on the 3' (C-terminal) end of the insert",,cloningMethod,FALSE,,geneticReagent,,, -3primeSiteDestroyed,"If 3' site was destroyed during cloning. (e.g. yes, no, unknown)","Yes, No, Unknown",,FALSE,,geneticReagent,,, -promoter,Promoter driving the expression of the insert in the plasmid,,,FALSE,,geneticReagent,,, -5primer,Primer to sequence the 5' end (N-terminal) of the insert,,,FALSE,,geneticReagent,,, -3primer,Primer to sequence the 3' end (C-terminal) of the insert.,,,FALSE,,geneticReagent,,, -vectorBackbone,Name of the backbone the plasmid is built on. (e.g pGBT9),,,FALSE,,geneticReagent,,, -vectorType,"Primary function of the plasmid. (e.g. mammalian expression, bacterial expression, etc.)","Mammalian Expression, Bacterial Expression, Gateway Entry Clone, Lentiviral, Adenoviral, AAV, RNAi, Luciferase, Cre/Lox, Yeast Expression, Worm Expression, Insect Expression, Plant Expression, Mouse Targeting, CRISPR, TALEN, Synthetic Biology, Transfer Vector, Unspecified, Other",,FALSE,,geneticReagent,,,list -backboneSize,Size in bp of the backbone without the insert,,,FALSE,,geneticReagent,,, -totalSize,Size of vector with insert. Derived from insertSize and backboneSize.,,,FALSE,,geneticReagent,,, -bacterialResistance,"Antibiotic(s) that should be used for selection in bacteria. (e.g. ampicillin, kanamycin, etc.)","Ampicillin, Kanamycin, Chloramphenicol, Tetracycline, Spectinomycin, Hygromycin, Bleocin(Zeocin), Gentamycin, Streptomycin, Nourseothricin(clonNat), Ampicillin and Bleocin (Zeocin), Ampicillin and Kanamycin, Ampicillin and Tetracycline, Ampicillin and Streptomycin, Ampicillin and Spectinomycin, Chloramphenicol and Ampicillin, Chloramphenicol and Bleocin (Zeocin), Chloramphenicol and Tetracycline, Chloramphenicol and Kanamycin, Chloramphenicol and Spectinomycin, Chloramphenicol and Gentamycin, Spectinomycin and Streptomycin, Other",,FALSE,,geneticReagent,,, -selectableMarker,"Are there any additional selection markers on this plasmid, for example, any mammalian selection markers or fluorescent proteins?","Neomycin, Puromycin, Hygromycin, Zeocin, Blasticidin, Gentamicin, TRP1, LEU1, URA3, HIS3, Basta, Other",,FALSE,,geneticReagent,,, -copyNumber,"If a plasmid produces a sufficient amount of DNA from a normal miniprep or if plasmid requires special growth conditions or it is difficult to grow. (e.g. high copy, low copy, unknown).","High Copy, Low Copy, Unknown",,FALSE,,geneticReagent,,, -growthTemp,At what temperature should the bacteria hosting the plasmid be grown,"37 C, 30 C, Room Temperature",,FALSE,,geneticReagent,,, -growthStrain,"The E.Coli strain that should be used to distribute the plasmid. (e.g. DH5alpha, NEB Stable, etc.)","DH5alpha, DH10B, NEB Stable, ccdb Survival, Pir1, Other",,FALSE,,geneticReagent,,, -hazardous,"Does the unmodified plasmid DNA, either in purified form or when introduced into bacterial or mammalian cells require handling at Biosafety Level 2 or higher?","Yes, No, Unknown",,TRUE,,geneticReagent,,, +geneticReagentDetails,Genetic reagents.,,"Component, geneticReagentId, insertName, insertEntrezId, gRNAshRNASequence, insertSize, insertSpecies, nTerminalTag, cTerminalTag, cloningMethod, 5primeCloningSite, 5primeSiteDestroyed, 3primeCloningSite, 3primeSiteDestroyed, promoter, 5primer, 3primer, vectorBackbone, vectorType, backboneSize, totalSize, bacterialResistance, selectableMarker, copyNumber, growthTemp, growthStrain, hazardous",FALSE,,geneticReagentDetails,"geneticReagentId, insertName, insertEntrezId, gRNAshRNASequence, insertSize, insertSpecies, nTerminalTag, cTerminalTag, cloningMethod, 5primeCloningSite, 5primeSiteDestroyed, 3primeCloningSite, 3primeSiteDestroyed, promoter, 5primer, 3primer, vectorBackbone, vectorType, backboneSize, totalSize, bacterialResistance, selectableMarker, copyNumber, growthTemp, growthStrain, hazardous",, +geneticReagentId,A unique identifier for the reagent.,,,FALSE,,geneticReagentDetails,,, +insertName,Name of the main gene insert in the plasmid.,,,TRUE,,geneticReagentDetails,,, +insertEntrezId,The entrez gene id for the gene insert,,,FALSE,,geneticReagentDetails,,, +gRNAshRNASequence,"The sequence of the gRNA or shRNA for the gene insert, if present. ",,,FALSE,,geneticReagentDetails,,, +insertSize,"Size, in bp, of the gene insert as it is in the plasmid.",,,FALSE,,geneticReagentDetails,,, +insertSpecies,Species of the insert,"Homo sapiens, Mus musculus, Rattus norvegicus",,TRUE,,geneticReagentDetails,,,list like +nTerminalTag,Any tags on the N terminal 5' end of the gene insert in the plasmid. Only tags that are in frame,,,FALSE,,geneticReagentDetails,,,list like +cTerminalTag,Any tags on the C terminal 3' end of the gene insert in the plasmid. Only tags that are in frame,,,FALSE,,geneticReagentDetails,,,list like +cloningMethod,"How the vector was constructed. (e.g. restriction enzyme, TOPO cloning, etc.)","Restriction Enzyme, TOPO cloning, Gateway Cloning, Ligation Independent Cloning, Gibson Cloning, Unknown",,FALSE,,geneticReagentDetails,,, +5primeCloningSite,"If Restriction Enzyme was selected as the cloning method, specifies what enzyme was used on the 5' (N-terminal) end of the insert",,cloningMethod,FALSE,,geneticReagentDetails,,, +5primeSiteDestroyed,"If 5' site was destroyed during cloning. (e.g. yes, no, unknown).","Yes, No, Unknown",,FALSE,,geneticReagentDetails,,, +3primeCloningSite,"If Restriction Enzyme was selected as the cloning method, specifies what enzyme was used on the 3' (C-terminal) end of the insert",,cloningMethod,FALSE,,geneticReagentDetails,,, +3primeSiteDestroyed,"If 3' site was destroyed during cloning. (e.g. yes, no, unknown)","Yes, No, Unknown",,FALSE,,geneticReagentDetails,,, +promoter,Promoter driving the expression of the insert in the plasmid,,,FALSE,,geneticReagentDetails,,, +5primer,Primer to sequence the 5' end (N-terminal) of the insert,,,FALSE,,geneticReagentDetails,,, +3primer,Primer to sequence the 3' end (C-terminal) of the insert.,,,FALSE,,geneticReagentDetails,,, +vectorBackbone,Name of the backbone the plasmid is built on. (e.g pGBT9),,,FALSE,,geneticReagentDetails,,, +vectorType,"Primary function of the plasmid. (e.g. mammalian expression, bacterial expression, etc.)","Mammalian Expression, Bacterial Expression, Gateway Entry Clone, Lentiviral, Adenoviral, AAV, RNAi, Luciferase, Cre/Lox, Yeast Expression, Worm Expression, Insect Expression, Plant Expression, Mouse Targeting, CRISPR, TALEN, Synthetic Biology, Transfer Vector, Transposon Vector, Unspecified, Other",,FALSE,,geneticReagentDetails,,,list like +backboneSize,Size in bp of the backbone without the insert,,,FALSE,,geneticReagentDetails,,, +totalSize,Size of vector with insert. Derived from insertSize and backboneSize.,,,FALSE,,geneticReagentDetails,,, +bacterialResistance,"Antibiotic(s) that should be used for selection in bacteria. (e.g. ampicillin, kanamycin, etc.)","Ampicillin, Kanamycin, Chloramphenicol, Tetracycline, Spectinomycin, Hygromycin, Bleocin(Zeocin), Gentamycin, Streptomycin, Nourseothricin(clonNat), Ampicillin and Bleocin (Zeocin), Ampicillin and Kanamycin, Ampicillin and Tetracycline, Ampicillin and Streptomycin, Ampicillin and Spectinomycin, Chloramphenicol and Ampicillin, Chloramphenicol and Bleocin (Zeocin), Chloramphenicol and Tetracycline, Chloramphenicol and Kanamycin, Chloramphenicol and Spectinomycin, Chloramphenicol and Gentamycin, Spectinomycin and Streptomycin, Other",,FALSE,,geneticReagentDetails,,, +selectableMarker,"Are there any additional selection markers on this plasmid, for example, any mammalian selection markers or fluorescent proteins?","Neomycin, Puromycin, Hygromycin, Kanamycin, Chloramphenicol, Zeocin, Blasticidin, Gentamicin, TRP1, LEU1, LEU2, URA3, HIS3, Basta, Other",,FALSE,,geneticReagentDetails,,, +copyNumber,"If a plasmid produces a sufficient amount of DNA from a normal miniprep or if plasmid requires special growth conditions or it is difficult to grow. (e.g. high copy, low copy, unknown).","High Copy, Low Copy, Unknown",,FALSE,,geneticReagentDetails,,, +growthTemp,At what temperature should the bacteria hosting the plasmid be grown,"37 C, 30 C, Room Temperature",,FALSE,,geneticReagentDetails,,, +growthStrain,"The E.Coli strain that should be used to distribute the plasmid. (e.g. DH5alpha, NEB Stable, etc.)","DH5alpha, DH10B, NEB Stable, ccdb Survival, Pir1, Other",,FALSE,,geneticReagentDetails,,, +hazardous,"Does the unmodified plasmid DNA, either in purified form or when introduced into bacterial or mammalian cells require handling at Biosafety Level 2 or higher?","Yes, No, Unknown",,TRUE,,geneticReagentDetails,,, vendorItem,The resource item associated with a vendor.,,"Component, vendorItemId, vendorId, resourceId, catalogNumber, catalogNumberURL",FALSE,,vendorItem,"vendorItemId, vendorId, resourceId, catalogNumber, catalogNumberURL","resource,vendor", vendorItemId,A unique identifier for the resource associated with a vendor. ,,,TRUE,,vendorItem,,, catalogNumber,The catalog number associated with the resource pertaining to the vendor that sells the resource.,,,TRUE,,vendorItem,,, catalogNumberURL,The url linking to the resource on the vendor's website. ,,,FALSE,,vendorItem,,, -vendor,A person or compnay offering the resource for sale.,,"Component, vendorId, vendorName, vendorURL",FALSE,,vendor,"vendorId, vendorName, vendorURL",, +vendor,A person or company offering the resource for sale.,,"Component, vendorId, vendorName, vendorUrl",FALSE,,vendor,"vendorId, vendorName, vendorUrl",, vendorId,A unique identifier for the vendor.,,,TRUE,,vendor,,, vendorName,The name of the vendor.,,,FALSE,,vendor,,, -vendorURL,The vendor website url associated with the resource.,,,FALSE,,vendor,,, -biobank,"A large collection of biological or medical data and tissue samples, amassed for research purposes.",,"Component, biobankId, resourceId, biobankName, biobankURL, specimenType, specimenTissueType, tumorType, diseaseType, specimenPreparationMethod, specimenFormat",FALSE,,biobank,"biobankId, resourceId, biobankName, biobankURL, specimenType, specimenTissueType, tumorType, diseaseType, specimenPreparationMethod, specimenFormat",resource, -biobankName,The name of the biobank. ,,,TRUE,,biobank,,, -biobankId,A unique identifier for the biobank.,,,TRUE,,biobank,,, -biobankURL,A URL for the biobank landing page.,,,TRUE,,biobank,,, -specimenType,The types of specimens that are banked.,"human tissue, xenograft tumors, cell lines",,TRUE,,biobank,,,list -specimenTissueType,The types of tissues that are banked.,"blood, tumor, cerebrospinal fluid, nerve, skin, bone, brain",,TRUE,,biobank,,,list -tumorType,"The types of tumors that are banked, if applicable.","cutaneous neurofibroma, plexiform neurofibroma, schwannoma, meningioma, malignant peripheral nerve sheath tumor, low grade glioma, high grade glioma, pheochromocytoma, optic nerve glioma, atypical neurofibroma, neurofibroma NOS, diffuse infiltrating neurofibroma, brain NOS",,TRUE,,biobank,,,list -diseaseType,"The diseases of the banked specimens, if applicable.","Neurofibromatosis type 1, Neurofibromatosis type 2, Schwannomatosis",,TRUE,,biobank,,,list -specimenPreparationMethod,The preservation methods used by the biobank.,"Fresh collected, Flash frozen, FFPE, Cryopreserved, OCT, RNA later, Formalin-fixed, Ethanol",,TRUE,,biobank,,,list -specimenFormat,How the specimens have been processed in preparation for distribution.,"whole tumor, slide, whole cell lysate, DNA, RNA",,TRUE,,biobank,,,list +vendorUrl,The vendor website url associated with the resource.,,,FALSE,,vendor,,, +biobankDetails,"A large collection of biological or medical data and tissue samples, amassed for research purposes.",,"Component, biobankId, resourceId, biobankName, biobankURL, specimenType, specimenTissueType, tumorType, diseaseType, specimenPreparationMethod, specimenFormat",FALSE,,biobankDetails,"biobankId, resourceId, biobankName, biobankURL, specimenType, specimenTissueType, tumorType, diseaseType, specimenPreparationMethod, specimenFormat",, +biobankName,The name of the biobank. ,,,TRUE,,biobankDetails,,, +biobankId,A unique identifier for the biobank.,,,FALSE,,biobankDetails,,, +biobankURL,A URL for the biobank landing page.,,,TRUE,,biobankDetails,,, +specimenType,The types of specimens that are banked.,"human tissue, xenograft tumors, cell lines",,TRUE,,biobankDetails,,,list like +specimenTissueType,The types of tissues that are banked.,"Blood, Tumor, Cerebrospinal Fluid, Nerve, Skin, Bone, Brain",,TRUE,,biobankDetails,,,list like +tumorType,"The types of tumors that are banked, if applicable.","cutaneous neurofibroma, plexiform neurofibroma, atypical neurofibroma, schwannoma, meningioma, malignant peripheral nerve sheath tumor, low grade glioma, high grade glioma, pheochromocytoma, optic nerve glioma, atypical neurofibroma, neurofibroma NOS, diffuse infiltrating neurofibroma, brain NOS, Other",,TRUE,,biobankDetails,,,list like +diseaseType,"The diseases of the banked specimens, if applicable.","Neurofibromatosis type 1, Neurofibromatosis type 2, Schwannomatosis",,TRUE,,biobankDetails,,,list like +specimenPreparationMethod,The preservation methods used by the biobank.,"Fresh collected, Flash frozen, FFPE, Cryopreserved, OCT, RNA later, Formalin-fixed, Ethanol",,TRUE,,biobankDetails,,,list like +specimenFormat,How the specimens have been processed in preparation for distribution.,"whole tumor, slide, cells, whole cell lysate, DNA, RNA",,TRUE,,biobankDetails,,,list like observation,"A remark, statement, or comment based on the resource.",,"Component, observationId, resourceId, publicationId, observationSubmitterName, synapseId, observationText, observationType, observationPhase, observationTime, observationTimeUnits, reliabilityRating, easeOfUseRating, observationLink",FALSE,,observation,"observationId, resourceId, publicationId, observationSubmitterName, synapseId, observationText, observationType, observationPhase, observationTime, observationTimeUnits, reliabilityRating, easeOfUseRating, observationLink","resource, investigator, publication", observationId,A unique identifier for the observation.,,,TRUE,,observation,,, observationSubmitterName,The name of the person submitting the observation. ,,,TRUE,,observation,,, synapseId,The synapse identifier for the person submitting the observation. ,,,FALSE,,observation,,, observationText,Free text observation about the resource.,,,TRUE,,observation,,, -observationType,Type of observation,"Body Length, Body weight, Coat Color, Disease Susceptibility, Feed Intake, Feeding Behavior, Growth rate, Motor Activity, Organ Development, Reflex Development, Reproductive Behavior, Social Behavior, Swimming Behavior, Tumor Growth, Issue, Depositor Comment, Usage Instructions, General Comment or Review, Other",,TRUE,,observation,,, -observationPhase,What t=0 for the observationTime is,"Adolescent, Adult, Death Phase, Embryo, Juvenile, Larval, Log Phase, Neonatal, Postnatal, Prenatal, Pupal, Stationary Phase, Weanling",,FALSE,,observation,,, +observationType,Type of observation,"Body Length, Body Weight, Coat Color, Disease Susceptibility, Feed Intake, Feeding Behavior, Growth Rate, Motor Activity, Organ Development, Reflex Development, Reproductive Behavior, Social Behavior, Swimming Behavior, Tumor Growth, Issue, Depositor Comment, Usage Instructions, General Comment or Review, Lifespan, Other",,TRUE,,observation,,,list like +observationPhase,What t=0 for the observationTime is,"adolescent, adult, death phase, embryo, juvenile, larval, log phase, neonatal, postnatal, prenatal, pupal, stationary phase, weanling",,FALSE,,observation,,, observationTime,When the observation was.,,,FALSE,,observation,,, observationTimeUnits,The unit of time pertaining to the observation,"days, weeks, months, years, hours, minutes, seconds, milliseconds",,FALSE,,observation,,, reliabilityRating,A 1-5 rating of the reliability of the resource; does the resource produce consistent and reliable results? Does the resource reasonably recapitulate the human disease it is intended to model? ,"1,2,3,4,5",,FALSE,,observation,,, @@ -71,42 +77,42 @@ observationLink,"A link/reference related to the observation being recorded. If resourceApplication,"Applications the resource can be used for. (i.e. western blot, immunofluorescence, etc.)",,"Component, resourceApplicationId, resourceId, source, applications, links",FALSE,,resourceApplication,"resourceApplicationId, resourceId, source, applications, links",resource, resourceApplicationId,A unique identifier for resrouce Application,,,TRUE,,resourceApplication,,, source,"The source of resource application information (e.g. Vendor, Community)","Community-reported, Investigator-reported, Vendor-reported",,TRUE,,resourceApplication,,, -applications,"One or more uses for the resource (e.g. western blot, immunofluorescence)","Western Blot, Immunofluorescence, ELISA, Immunohistochemistry, Immunoprecipitation, Tumor Growth Studies, Immunohistochemistry (Paraffin-Embedded), Immunocytochemistry, Immunohistochemistry (Frozen Sections), Flow Cytometry, Affinity Purification, Microarray",,TRUE,,resourceApplication,,,list -links,shareable links related to the resource,,,FALSE,,resourceApplication,,,list -antibody,"A blood protein produced in response to and counteracting a specific antigen. Antibodies combine chemically with substances which the body recognizes as alien, such as bacteria, viruses, and foreign substances in the blood.",,"Component, antibodyId, uniprotId, targetAntigen, clonality, cloneId, reactiveSpecies, conjugate, hostOrganism",FALSE,,antibody,,, -antibodyId,A unique identifier for the antibody.,,,TRUE,,antibody,"antibodyId, uniprotId, targetAntigen, clonality, cloneId, reactiveSpecies, conjugate, hostOrganism",, -uniprotId,The uniprotId of the antibody.,,,TRUE,,antibody,,, -targetAntigen,Antigen that is targeted by antibody. (e.g. Neurofibromin 1 human),,,TRUE,,antibody,,, -clonality,They type of clonality of the antibody,"Unknown, Cocktail, Control, Isotype Control, Monoclonal, Monoclonal Secondary, Polyclonal, Polyclonal Secondary, OligoClonal, Recombinant, Recombinant Monoclonal, Recombinant Monoclonal Secondary, Recombinant Polyclonal, Recombinant Polyclonal Secondary",,TRUE,,antibody,,, -cloneId,Identification of clone (e.g. 2D1),,,FALSE,,antibody,,, -reactiveSpecies,Species the antibody has been shown to crossreact with the target protein. ,"Avian, Bovine, Canine, Chicken, Cow, Dog, Donkey, Feline, Fish, Guinea pig, Hamster, Human, Monkey, Mouse, Non-human primate, Other, Pig, Porcine, Rabbit, Rat, Rodent, Sheep, Simian, Zebrafish",,TRUE,,antibody,,,list -conjugate,Is the antibody conjugated or nonconjugated,"Conjugated, Nonconjugated",,TRUE,,antibody,,, -hostOrganism,The species of the organism that hosts the antibody,"Mouse, Rabbit",,TRUE,,antibody,,, +applications,"One or more uses for the resource (e.g. western blot, immunofluorescence)","Western Blot, Immunofluorescence, ELISA, Immunohistochemistry, Immunoprecipitation, Immunochromatography, Tumor Growth Studies, Gold Immunochromatographic Assay, Immunoelectron Microscopy, Immunogold Silver Staining, Immunohistochemistry (Paraffin-Embedded), Immunocytochemistry, Immunohistochemistry (Frozen Sections), Flow Cytometry, Affinity Purification, Microarray",,TRUE,,resourceApplication,,,list like +links,shareable links related to the resource,,,FALSE,,resourceApplication,,,list like +antibodyDetails,"A blood protein produced in response to and counteracting a specific antigen. Antibodies combine chemically with substances which the body recognizes as alien, such as bacteria, viruses, and foreign substances in the blood.",,"Component, antibodyId, uniprotId, targetAntigen, clonality, cloneId, reactiveSpecies, conjugate, hostOrganism",FALSE,,antibodyDetails,"antibodyId, uniprotId, targetAntigen, clonality, cloneId, reactiveSpecies, conjugate, hostOrganism",, +antibodyId,A unique identifier for the antibody.,,,FALSE,,antibodyDetails,"antibodyId, uniprotId, targetAntigen, clonality, cloneId, reactiveSpecies, conjugate, hostOrganism",, +uniprotId,The uniprotId of the protein targeted by the antibody.,,,FALSE,,antibodyDetails,,, +targetAntigen,Antigen that is targeted by antibody. (e.g. Neurofibromin 1 human),,,TRUE,,antibodyDetails,,, +clonality,They type of clonality of the antibody,"Unknown, Cocktail, Control, Isotype Control, Monoclonal, Monoclonal Secondary, Polyclonal, Polyclonal Secondary, OligoClonal, Recombinant, Recombinant Monoclonal, Recombinant Monoclonal Secondary, Recombinant Polyclonal, Recombinant Polyclonal Secondary",,TRUE,,antibodyDetails,,, +cloneId,Identification of clone (e.g. 2D1),,,FALSE,,antibodyDetails,,, +reactiveSpecies,Species the antibody has been shown to crossreact with the target protein. ,"Human, Mouse, Rat, Chicken, Rabbit, Pig, Dog, Zebrafish, Fish, Non-human primate, Guinea pig, Hamster, Cow, Monkey, Avian, Horse, Rodent, Drosophila, Unknown",,TRUE,,antibodyDetails,,,list like +conjugate,Is the antibody conjugated or nonconjugated,"Conjugated, Nonconjugated",,TRUE,,antibodyDetails,,, +hostOrganism,The species of the organism that hosts the antibody,"Mouse, Rabbit, Unknown",,TRUE,,antibodyDetails,,, donor,"A person, animal, etc. who is the contributor of the resource.",,"Component, donorId, parentDonorId, transplantationDonorId, species, sex, age, race",FALSE,,donor,"donorId, parentDonorId, transplantationDonorId, species, sex, age, race",, donorId,A uniqe identifier for donor.,,,TRUE,,donor,,, parentDonorId,The ID of the parent donor.,,donorId,FALSE,,donor,,, -species,The species of the individual the resource was derived from.,"Homo sapiens, Mus musculus, Mus musculus (humanized), Rattus norvegicus, Drosophila melanogaster, Rhesus macaque, Pan troglodytes, Gallus gallus, Sus scrofa, Oryctolagus cuniculus,Danio rerio,Escherichia coli",,TRUE,,donor,,, -sex,The sex of the indiviudal from which the resource was derived from.,"Male, Female, Unknown",,FALSE,,donor,,, +species,The species of the individual the resource was derived from.,"Homo sapiens, Mus musculus, Mus musculus (humanized), Rattus norvegicus, Drosophila melanogaster, Saccharomyces cerevisiae, Rhesus macaque, Cricetulus griseus, Xenopus laevis, Canis lupus familiaris, Pan troglodytes, Gallus gallus, Sus scrofa, Oryctolagus cuniculus,Danio rerio,Escherichia coli",,TRUE,,donor,,,list like +sex,The sex of the individual from which the resource was derived from.,"Male, Female, Unknown",,FALSE,,donor,,, age,That age of the individual from which the resource was derived from.,,,FALSE,,donor,,, race,The ethnicity of the individual the resource was derived from.,,,FALSE,,donor,,, -cellLine,A cell culture selected for uniformity from a cell population derived from a usually homogeneous tissue source (such as an organ).,,"Component, cellLineId, donorId, organ, tissue, cellLineCategory, originYear, strProfile, populationDoublingTime, resistance, contaminatedMisidentified, cellLineGeneticDisorder, cellLineManifestation",FALSE,,cellLine,"cellLineId, donorId, organ, tissue, cellLineCategory, originYear, strProfile, populationDoublingTime, resistance, contaminatedMisidentified, cellLineGeneticDisorder, cellLineManifestation",donor, -cellLineId,A unique identifier for the cell line.,,,TRUE,,cellLine,,, -organ,The organ the cell line is derived from.,"Blood, Bone marrow, Brain, Breast, Bursa of fabricius, Colon, Kidney, Lung, Lymph node, Mammary gland, Nerves, Nose, Ovary, Pancreas, Prostate, Skin, Spleen",,FALSE,,cellLine,,, -tissue,The tissue the cell line is derived from.,"Blood, Bone marrow, Buccal mucosa, Buffy coat, Cerebral cortex, Dorsal root ganglion, Embryonic tissue, Meninges, Nerve tissue, Optic nerve, Plasma, Primary tumor, Sciatic nerve, Serum, Splenocyte, Unspecified, Whole brain",,FALSE,,cellLine,,, -cellLineCategory,The category to which the cell line belongs.,"Cancer cell line, Conditionally immortalized cell line, Embryonic stem cell, Factor-dependent cell line, Finite cell line, Hybridoma, Induced pluripotent stem cell, Somatic stem cell, Spontaneously immortalized cell line, Stromal cell line, Telomerase immortalized cell line, Transformed cell line, Undefined cell line type",,FALSE,,cellLine,,, -originYear,The year the cell line orginated.,,,FALSE,,cellLine,,, -strProfile,Short tandem repeat profile information.,,,FALSE,,cellLine,,, -populationDoublingTime,Time for cell line to double,,,FALSE,,cellLine,,, -resistance,List of compounds if a cell line has been selected for.,,,FALSE,,cellLine,,,list -contaminatedMisidentified,If a cell line has been contaminated or misidentified,,,FALSE,,cellLine,,, -cellLineGeneticDisorder,"Genetic diseases are diseases in which inherited genes predispose to increased risk. The genetic disorders associated with cancer often result from an alteration or mutation in a single gene. The diseases range from rare dominant cancer family syndrome to familial tendencies in which low-penetrance genes may interact with other genes or environmental factors to induce cancer. Research may involve clinical, epidemiologic, and laboratory studies of persons, families, and populations at high risk of these disorders. [ NCI ]","Neurofibromatosis type 1, Neurofibromatosis type 2, Schwannomatosis, No known disease",,FALSE,http://purl.obolibrary.org/obo/NCIT_C3101,cellLine,,,list -cellLineManifestation,"Manifestations/symptoms that this resource is used to model (e.g. tumor type, behavioral phenotype, etc.)",,,FALSE,,cellLine,,,list +cellLineDetails,A cell culture selected for uniformity from a cell population derived from a usually homogeneous tissue source (such as an organ).,,"Component, cellLineId, donorId, organ, tissue, cellLineCategory, originYear, strProfile, populationDoublingTime, resistance, contaminatedMisidentified, cellLineGeneticDisorder, cellLineManifestation",FALSE,,cellLineDetails,"cellLineId, donorId, organ, tissue, cellLineCategory, originYear, strProfile, populationDoublingTime, resistance, contaminatedMisidentified, cellLineGeneticDisorder, cellLineManifestation",donor, +cellLineId,A unique identifier for the cell line.,,,FALSE,,cellLineDetails,,, +organ,The organ the cell line is derived from.,"Biliary Tract, Bladder, Bone Marrow, Brain, Breast, Bronchial Tree, Duct, Epididymis, Esophagus, Fallopian Tube, Gallbladder, Gland, Gonad, Heart, Intestine, Kidney, Liver, Lung, Lymph Node, Ear, Eye, Nose, Tongue, Pancreas, Penis, Seminal Vesicle, Skin, Spermatic Cord, Spinal Cord, Spleen, Stomach, Thymus Gland, Thyroid Gland, Tonsil, Trachea, Tracheobronchial Tree, Ureter, Urethra, Uterus, Vagina, Vulva",,FALSE,,cellLineDetails,,, +tissue,The tissue the cell line is derived from.,"Blood, Bone marrow, Buccal mucosa, Buffy coat, Cerebral cortex, Dorsal root ganglion, Embryonic tissue, Meninges, Nerve tissue, Optic nerve, Plasma, Primary tumor, Sciatic nerve, Serum, Splenocyte, Unspecified, Urine, Whole brain",,FALSE,,cellLineDetails,,, +cellLineCategory,The category to which the cell line belongs.,"Cancer cell line, Conditionally immortalized cell line, Embryonic stem cell, Factor-dependent cell line, Finite cell line, Hybridoma, Hybrid cell line, Induced pluripotent stem cell, Somatic stem cell, Spontaneously immortalized cell line, Stromal cell line, Telomerase immortalized cell line, Transformed cell line, Undefined cell line type",,FALSE,,cellLineDetails,,, +originYear,The year the cell line orginated.,,,FALSE,,cellLineDetails,,, +strProfile,Short tandem repeat profile information.,,,FALSE,,cellLineDetails,,, +populationDoublingTime,Time for cell line to double,,,FALSE,,cellLineDetails,,, +resistance,List of compounds if a cell line has been selected for.,,,FALSE,,cellLineDetails,,,list like +contaminatedMisidentified,If a cell line has been contaminated or misidentified,,,FALSE,,cellLineDetails,,, +cellLineGeneticDisorder,"Genetic diseases are diseases in which inherited genes predispose to increased risk. The genetic disorders associated with cancer often result from an alteration or mutation in a single gene. The diseases range from rare dominant cancer family syndrome to familial tendencies in which low-penetrance genes may interact with other genes or environmental factors to induce cancer. Research may involve clinical, epidemiologic, and laboratory studies of persons, families, and populations at high risk of these disorders. [ NCI ]","Neurofibromatosis type 1, Neurofibromatosis type 2, Schwannomatosis, No known genetic disorder",,FALSE,http://purl.obolibrary.org/obo/NCIT_C3101,cellLineDetails,,,list like +cellLineManifestation,"Manifestations/symptoms that this resource is used to model (e.g. tumor type, behavioral phenotype, etc.)",,,FALSE,,cellLineDetails,,,list like mutationDetails,"The changing of the structure of a gene, resulting in a variant form that may be transmitted to subsequent generations",,"Component, mutationDetailsId, externalMutationID, alleleType, mutationType, mutationMethod, affectedGeneSymbol, affectedGeneName, sequenceVariation, proteinVariation, animalModelMutation, humanClinVarMutation, chromosome",FALSE,,mutationDetails,"mutationDetailsId, externalMutationID, alleleType, mutationType, mutationMethod, affectedGeneSymbol, affectedGeneName, sequenceVariation, proteinVariation, animalModelMutation, humanClinVarMutation, chromosome",, mutationDetailsId,A unique identifier for mutation.,,,FALSE,,mutationDetails,,, externalMutationID,"An identifier from an organism database such as MGI or other curated variant resource, if available. ",,,FALSE,,mutationDetails,,, -mutationType,"The type of the mutation, vocabulary aligned with MGI mutation types. ","Disruption caused by insertion of vector, Duplication, Insertion, Insertion of gene trap vector, Intergenic deletion, Intragenic deletion, Inversion, Loss of heterozygosity (unspecified mechanism), Not Applicable, Not Specified, Nucleotide repeat expansion, Nucleotide substitutions, Other, Single point mutation, Translocation, Transposon insertion, Undefined, Viral insertion",,FALSE,,mutationDetails,,,list -mutationMethod,"The method used to alter the resource, vocabulary aligned with and expanded upon MGI allele origin types. ","Chemically induced (ENU), Chemically induced (other), Chemically and radiation induced, Endonuclease-mediated (CRISPR), Endonuclease-mediated (TALEN), Gene trapped, QTL, Radiation induced, Spontaneous, Targeted, Transgenic, Transposon induced",,FALSE,,mutationDetails,,,list -alleleType,"The type of genetic alteration of the resource, vocabulary aligned with MGI allele subtypes. ","Conditional ready, Constitutively active, Dominant negative, Humanized sequence, Hypomorph, Inducible, Inserted expressed sequence, Knockdown, Modified isoform(s), No functional change, Null/knockout, Recombinase, Reporter, RMCE-Ready, Transactivator, Transposase, Transposon concatemer",,FALSE,,mutationDetails,,,list +mutationType,"The type of the mutation, vocabulary aligned with MGI mutation types, and expanded to include additional types. ","Disruption caused by insertion of vector, Duplication, Insertion, Insertion of gene trap vector, Intergenic deletion, Intragenic deletion, Inversion, Loss of heterozygosity (unspecified mechanism), Not Applicable, Not Specified, Nucleotide repeat expansion, Nucleotide substitutions, Other, Single point mutation, Translocation, Transposon insertion, Undefined, Viral insertion, Microdeletion, Homozygous deletion, Loss of heterozygosity (mitotic recombination), Loss of heterozygosity (deletion), Stable knockdown, Exogenous DNA expression",,FALSE,,mutationDetails,,,list like +mutationMethod,"The method used to alter the resource, vocabulary aligned with and expanded upon MGI allele origin types. ","Chemically induced (ENU), Chemically induced (other), Chemically and radiation induced, Endonuclease-mediated (CRISPR), Endonuclease-mediated (TALEN), Gene trapped, QTL, Radiation induced, Spontaneous, Targeted, Transgenic, Transposon induced, Unknown",,FALSE,,mutationDetails,,,list like +alleleType,"The type of genetic alteration of the resource, vocabulary aligned with MGI allele subtypes. ","Conditional ready, Constitutively active, Dominant negative, Humanized sequence, Hypomorph, Inducible, Inserted expressed sequence, Knockdown, Modified isoform(s), No functional change, Null/knockout, Recombinase, Reporter, RMCE-Ready, Transactivator, Transposase, Transposon concatemer",,FALSE,,mutationDetails,,,list like affectedGeneSymbol,"The gene symbol for the mutated gene. (e.g. NF1, SUZ12, SMARCB1, P53, etc.)",,,FALSE,,mutationDetails,,, affectedGeneName,Gene name for the affected gene (e.g. neurofibromin 1),,,FALSE,,mutationDetails,,, sequenceVariation,Important sequence variations (e.g. g.123_127del). See http://varnomen.hgvs.org/ for the sequence variation nomenclature. ,,,FALSE,http://varnomen.hgvs.org/,mutationDetails,,, @@ -114,35 +120,34 @@ proteinVariation,The protein consequence of the mutation described in sequence v animalModelMutation,"A description of the specific mutation(s) created in the genome. (e.g. A neomycin resistance cassette replaced the first 42 codons of exon 31, the exon 31 splice acceptor site, and approximately 2 kb of intron 30.)",,,FALSE,,mutationDetails,,, humanClinVarMutation,"The human equivalent, of the mutation being described in ClinVar/HGVS notation. Can be used to link animal model mutations to the mutation they are modeling in human disease. ",,,FALSE,,mutationDetails,,, chromosome,Chromosome number of affected gene. (e.g. 11),,,FALSE,,mutationDetails,,, -mutation,(intermediary table),,"Component, mutationId, mutationDetailsId, animalModelId, cellLineId",FALSE,,mutation,"mutationId, mutationDetailsId, animalModelId, cellLineId","mutationDetails, animalModel, cellLine", +mutation,(intermediary table),,"Component, mutationId, mutationDetailsId, animalModelId, cellLineId",FALSE,,mutation,"mutationId, mutationDetailsId, animalModelId, cellLineId","mutationDetails, animalModelDetails, cellLineDetails", mutationId,A unique identifier for the mutation burden of the resource.,,,FALSE,,mutation,,, -animalModel,"An animal sufficiently like humans in its anatomy, physiology, or response to a pathogen to be used in medical research in order to obtain results that can be extrapolated to human medicine.",,"Component, animalModelId, donorId, transplantationDonorId, animalState, backgroundStrain, backgroundSubstrain, strainNomenclature, generation, transplantationType, animalModelGeneticDisorder, animalModelOfManifestation",FALSE,,animalModel,"animalModelId, donorId, animalState, backgroundStrain, backgroundSubstrain, strainNomenclature, generation, transplantationType, transplantationDonorId, animalModelGeneticDisorder, animalModelOfManifestation",donor, -animalModelId,A unique identifier for the animal model.,,,TRUE,,animalModel,,, -animalState,"State the animal is in according to the vendor/developer. (e.g. embryo, sperm, live)",,,FALSE,,animalModel,,, -backgroundStrain,"An assigned name that describes the genetic make-up (all its alleles at all loci) except the mutated gene of interest and a very small amount of other genetic material, generally from one or two other strains. Correct strain nomenclature indicates what a mutant strain’s background is.",,,FALSE,,animalModel,,, -backgroundSubstrain,"The substrain is a particular variety of a strain. For example, a C57BL/6 mice may have a substrain of C57BL/6J, C57BL/6Tac, or another substrain. ",,,FALSE,Sage Bionetworks,animalModel,,, -strainNomenclature,The standard nomenclature for the strain. (e.g. B6.129S2-NF1tm1Tyj/J). Set by the International Committee on Standardized Genetic Nomenclature for Mice. See http://www.informatics.jax.org/mgihome/nomen/strains.shtml for nomenclature information.,,,FALSE,http://www.informatics.jax.org/mgihome/nomen/strains.shtml,animalModel,,, -generation,The generation of the animal model. (e.g. 13),,,FALSE,,animalModel,,, -transplantationType,"Type of transplantation involved in the experiment, derived from MESH","allograft, xenograft, autograft, isograft",,FALSE,,animalModel,,, -transplantationDonorId,The donor indentifier number for the transplantion donor. ,,donorId,FALSE,,animalModel,,, -animalModelGeneticDisorder,"Genetic diseases are diseases in which inherited genes predispose to increased risk. The genetic disorders associated with cancer often result from an alteration or mutation in a single gene. The diseases range from rare dominant cancer family syndrome to familial tendencies in which low-penetrance genes may interact with other genes or environmental factors to induce cancer. Research may involve clinical, epidemiologic, and laboratory studies of persons, families, and populations at high risk of these disorders. [ NCI ]","Neurofibromatosis type 1, Neurofibromatosis type 2, Schwannomatosis, No known disease",,TRUE,http://purl.obolibrary.org/obo/NCIT_C3101,animalModel,,,list -animalModelOfManifestation,"Manifestations/symptoms that this resource is used to model (e.g. tumor type, behavioral phenotype, etc.) ",,,TRUE,,animalModel,,,list +animalModelDetails,"An animal sufficiently like humans in its anatomy, physiology, or response to a pathogen to be used in medical research in order to obtain results that can be extrapolated to human medicine.",,"Component, animalModelId, donorId, transplantationDonorId, animalState, backgroundStrain, backgroundSubstrain, strainNomenclature, generation, transplantationType, animalModelGeneticDisorder, animalModelOfManifestation",FALSE,,animalModelDetails,"animalModelId, donorId, animalState, backgroundStrain, backgroundSubstrain, strainNomenclature, generation, transplantationType, transplantationDonorId, animalModelGeneticDisorder, animalModelOfManifestation",donor, +animalModelId,A unique identifier for the animal model.,,,FALSE,,animalModelDetails,,, +animalState,"State the animal is in according to the vendor/developer. (e.g. embryo, sperm, live)",,,FALSE,,animalModelDetails,,, +backgroundStrain,"An assigned name that describes the genetic make-up (all its alleles at all loci) except the mutated gene of interest and a very small amount of other genetic material, generally from one or two other strains. Correct strain nomenclature indicates what a mutant strain’s background is.",,,FALSE,,animalModelDetails,,, +backgroundSubstrain,"The substrain is a particular variety of a strain. For example, a C57BL/6 mice may have a substrain of C57BL/6J, C57BL/6Tac, or another substrain. ",,,FALSE,Sage Bionetworks,animalModelDetails,,, +strainNomenclature,The standard nomenclature for the strain. (e.g. B6.129S2-NF1tm1Tyj/J). Set by the International Committee on Standardized Genetic Nomenclature for Mice. See http://www.informatics.jax.org/mgihome/nomen/strains.shtml for nomenclature information.,,,FALSE,http://www.informatics.jax.org/mgihome/nomen/strains.shtml,animalModelDetails,,, +generation,The generation of the animal model. (e.g. 13),,,FALSE,,animalModelDetails,,, +transplantationType,"Type of transplantation involved in the experiment, derived from MESH","allograft, xenograft, autograft, isograft",,FALSE,,animalModelDetails,,, +transplantationDonorId,The donor indentifier number for the transplantion donor. ,,donorId,FALSE,,animalModelDetails,,, +animalModelGeneticDisorder,"Genetic diseases are diseases in which inherited genes predispose to increased risk. The genetic disorders associated with cancer often result from an alteration or mutation in a single gene. The diseases range from rare dominant cancer family syndrome to familial tendencies in which low-penetrance genes may interact with other genes or environmental factors to induce cancer. Research may involve clinical, epidemiologic, and laboratory studies of persons, families, and populations at high risk of these disorders. [ NCI ]","Neurofibromatosis type 1, Neurofibromatosis type 2, Schwannomatosis, No known genetic disorder",,TRUE,http://purl.obolibrary.org/obo/NCIT_C3101,animalModelDetails,,,list like +animalModelOfManifestation,"Manifestations/symptoms that this resource is used to model (e.g. tumor type, behavioral phenotype, etc.) ",,,TRUE,,animalModelDetails,,,list like development,"resourceId, investigatorId, publicationId, funderId (intermediary table)",,"Component, developmentId, resourceId, investigatorId, publicationId, funderId",FALSE,,development,"developmentId, resourceId, investigatorId, publicationId, funderId","resource, investigator, publication, funder", developmentId,A unique identifier for the development of the resource.,,,TRUE,,development,,, funder,A person or organization that provides money for a particular resource.,,"Component, funderId, funderName",FALSE,,funder,"funderId, funderName",, funderId,A unique identifier for the funder of the resource.,,,FALSE,,funder,,, funderName,The name of the person or agency that funded the development of the resource.,,,FALSE,,funder,,, -investigator,A person who carries out a formal inquiry or investigation into the development of the resource.,,"Component, investigatorId, orcid, investigatorName, institution, investigatorWebsite, investigatorSynapseId",FALSE,,investigator,"investigatorId, orcid, investigatorName, institution, investigatorWebsite, investigatorSynapseId",, -investigatorId,A unique identifier for the investigator.,,,TRUE,,investigator,,, +investigator,A person who carries out a formal inquiry or investigation into the development of the resource.,,"Component, investigatorId, orcid, investigatorName, institution, investigatorSynapseId",FALSE,,investigator,"investigatorId, orcid, investigatorName, institution, investigatorSynapseId",, +investigatorId,A unique identifier for the investigator.,,,FALSE,,investigator,,, orcid,The orcidId of the investigator that developed the resource,,,FALSE,,investigator,,, -investigatorName,The name of the investigator responsible for devleoping the resource.,,,TRUE,,investigator,,, +investigatorName,The name of the investigator responsible for developing the resource.,,,TRUE,,investigator,,, institution,The insitution of the investator,,,FALSE,,investigator,,, -investigatorWebsite,The url to the investigator's laboratory website corresponding to the resource.,,,FALSE,,investigator,,, investigatorSynapseId,The synapse identifier for the investigator.,,,FALSE,,investigator,,, publication,Initial publication associated with the resource.,,"Component, publicationId, publicationTitle, authors, abstract, journal, publicationDate, pmid, doi, citation, publicationDateUnix",FALSE,,publication,"publicationId, publicationTitle, authors, abstract, journal, publicationDate, pmid, doi, citation, publicationDateUnix",, publicationId,A unique identifier for the publication.,,,FALSE,,publication,,, publicationTitle,The title of the publication associated with the resource.,,,TRUE,,publication,,, -authors,Writers of the publication.,,,FALSE,,publication,,,list +authors,Writers of the publication.,,,FALSE,,publication,,,list like abstract,"A brief, comprehensive summary of the contents of a publication.",,,FALSE,,publication,,, journal,The name of the periodical publication in which the paper was published.,,,FALSE,,publication,,, publicationDate,The date of the paper's publication.,,,FALSE,,publication,,,