diff --git a/opentelemetry-api/src/opentelemetry/propagate/__init__.py b/opentelemetry-api/src/opentelemetry/propagate/__init__.py
index afe406fb59..c0d838863f 100644
--- a/opentelemetry-api/src/opentelemetry/propagate/__init__.py
+++ b/opentelemetry-api/src/opentelemetry/propagate/__init__.py
@@ -129,28 +129,31 @@ def inject(
     "tracecontext,baggage",
 )
 
-
-for propagator in environ_propagators.split(","):
-    propagator = propagator.strip()
-
-    try:
-        propagators.append(  # type: ignore
-            next(  # type: ignore
-                iter(  # type: ignore
-                    entry_points(  # type: ignore
-                        group="opentelemetry_propagator",
-                        name=propagator,
+# Simplified logic to handle "none" case
+if environ_propagators.lower() == "none":
+    propagators = []
+else:
+    propagators = []
+    for propagator in environ_propagators.split(","):
+        propagator = propagator.strip()
+        try:
+            propagators.append(  # type: ignore
+                next(  # type: ignore
+                    iter(  # type: ignore
+                        entry_points(  # type: ignore
+                            group="opentelemetry_propagator",
+                            name=propagator,
+                        )
                     )
-                )
-            ).load()()
-        )
-    except StopIteration:
-        raise ValueError(
-            f"Propagator {propagator} not found. It is either misspelled or not installed."
-        )
-    except Exception:  # pylint: disable=broad-exception-caught
-        logger.exception("Failed to load propagator: %s", propagator)
-        raise
+                ).load()()
+            )
+        except StopIteration:
+            raise ValueError(
+                f"Propagator {propagator} not found. It is either misspelled or not installed."
+            )
+        except Exception:  # pylint: disable=broad-exception-caught
+            logger.exception("Failed to load propagator: %s", propagator)
+            raise
 
 
 _HTTP_TEXT_FORMAT = composite.CompositePropagator(propagators)  # type: ignore
diff --git a/opentelemetry-api/tests/propagators/test_propagators.py b/opentelemetry-api/tests/propagators/test_propagators.py
index f0554ad281..a17dad6877 100644
--- a/opentelemetry-api/tests/propagators/test_propagators.py
+++ b/opentelemetry-api/tests/propagators/test_propagators.py
@@ -49,6 +49,25 @@ def test_propagators(propagators):
 
         reload(opentelemetry.propagate)
 
+    @patch.dict(environ, {OTEL_PROPAGATORS: "none"})
+    @patch("opentelemetry.propagators.composite.CompositePropagator")
+    def test_no_propagators_loaded(self, mock_compositehttppropagator):
+        # Verify if exception is raised without the fix
+        with self.assertRaises(Exception):
+            from opentelemetry.propagate import get_global_textmap
+
+            get_global_textmap()
+
+        # Apply fix and verify propagators is empty, with no exception raised
+        try:
+            from opentelemetry.propagate import get_global_textmap
+
+            mock_compositehttppropagator.assert_called_with(
+                []
+            )  # Validate empty list of propagators
+        except Exception as e:
+            self.fail(f"Test failed unexpectedly with an exception: {e}")
+
     @patch.dict(environ, {OTEL_PROPAGATORS: "a,  b,   c  "})
     @patch("opentelemetry.propagators.composite.CompositePropagator")
     @patch("opentelemetry.util._importlib_metadata.entry_points")