diff --git a/.changeset/rotten-apples-greet.md b/.changeset/rotten-apples-greet.md
new file mode 100644
index 0000000000..10d47190d3
--- /dev/null
+++ b/.changeset/rotten-apples-greet.md
@@ -0,0 +1,5 @@
+---
+'@primer/view-components': patch
+---
+
+Ensure condition is checked when mutations occur in SelectPanelElement.
diff --git a/app/components/primer/alpha/select_panel_element.ts b/app/components/primer/alpha/select_panel_element.ts
index e4cb8f6fdb..6987d7b59f 100644
--- a/app/components/primer/alpha/select_panel_element.ts
+++ b/app/components/primer/alpha/select_panel_element.ts
@@ -250,8 +250,10 @@ export class SelectPanelElement extends HTMLElement {
       body()
     } else {
       const mutationObserver = new MutationObserver(() => {
-        body()
-        mutationObserver.disconnect()
+        if (condition()) {
+          body()
+          mutationObserver.disconnect()
+        }
       })
 
       mutationObserver.observe(this, {childList: true, subtree: true})