Support for Large Sparse Matrices in Signac

[ShanshanHe-44]

Hi Signac Team,

I hope you’re doing well!

I’m currently working on a project where the number of peaks in the matrix exceeds the matrix size limitation (2^31-1). To address this, I’ve used spam and spam64 to create a large sparse matrix.

I was wondering if the Signac ATAC functions support this type of matrix when creating a Seurat object?

Thank you for your guidance!

Best regards,
Shanshan

[timoast]

We hope to support this in the future, as with disk-backed matrices as mentioned here: #1507