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🌳 Welcome to the iPhyloGeo++ wiki! 🌳

iPhyloGeo++ is a bioinformatics pipeline dedicated to the analysis of phylogeography. iPhyloGeo++ is an open-source multi-platform application designed by the team of Professor Nadia Tahiri (University of Sherbrooke, Quebec, Canada). It is implemented in Python. This tool can be used to obtain trees from climatic data of the regions where the samples have been collected. Those climatic trees are then used for topological and evolutionary comparison against phylogenetic trees from multiple sequence alignments (MSAs) using the Least Square (LS) metric. MSAs that yield trees with a significant LS value are then optionally saved in folders with their respective tree. The output.csv file contains the information of all the significant MSAs information (see Worflow Section for more details).

iPhyloGeo++ offers the following features:

• Select a sequence Fasta file and climatic file in an accepted format (CSV)
• Runs a global sequence alignment from the Fasta file.
• Shows climatic data with location
• Calculates the evolutionary distance depending on the topology with the climate provided using LS metric.
• Displays the MSAs that yield trees with a significant LS, it can be saved as CSV.

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Please email us at: [email protected] for any question or feedback.