call somatic SVs

[DayTimeMouse]

Hi,

Thanks for developing this awesome tool.

I'd like to call somatic structural variants (SVs) using paired tumor and normal samples. However, cuteSV can only process one sample at a time.

I am unsure about the next steps after obtaining the tumor.vcf and normal.vcf files.

Best wishes.

[tjiangHIT]

Hello @DayTimeMouse,

Thanks for using cuteSV. You can call SVs on each sample, and then use tools like truvari or surviour to select the SVs that are only included in the tumor sample.

Best regards,
Tao