From 7d25af19748702473a252ec78239551199cea8d0 Mon Sep 17 00:00:00 2001 From: Matiss Date: Tue, 23 Apr 2024 13:57:05 +0100 Subject: [PATCH] Update README.md --- README.md | 3 +-- 1 file changed, 1 insertion(+), 2 deletions(-) diff --git a/README.md b/README.md index d42296c..0091a3b 100755 --- a/README.md +++ b/README.md @@ -4,8 +4,7 @@ ## Introduction -**nf-core/yascp** is a bioinformatics best-practice analysis pipeline for deconvolution, qc, clustering, integration of a single cell datasets. -This is a large scale single-cell pipeline developed initially for processing Cardinal project samples, however it is applicable to any other scRNA analysis. The pipeline has been inspired by [deconvolution](https://github.com/wtsi-hgi/nf_scrna_deconvolution.git ), [cellbender](https://github.com/wtsi-hgi/nf_cellbender ) and [qc](https://github.com/wtsi-hgi/nf_qc_cluster/tree/main ) pipelines initially developed in Anderson lab. +**nf-core/yascp** is a bioinformatics best-practice analysis pipeline tailored for deconvolution, quality control, clustering, and integration of single-cell datasets. Developed under the leadership of N.Soranzo at the Human Genetics Informatics (HGI), this large-scale single-cell pipeline was originally crafted for the Cardinal project (profiling UKBB and ELGH participants) but is versatile enough for broader scRNA analysis applications. The foundational ideas were inspired by earlier pipelines from Anderson lab but has been expanded, specifically those for [deconvolution](https://github.com/wtsi-hgi/nf_scrna_deconvolution.git), [cellbender](https://github.com/wtsi-hgi/nf_cellbender), and [quality control and clustering](https://github.com/wtsi-hgi/nf_qc_cluster/tree/main). This ensures a robust integration of proven methodologies tailored to meet the demands of expansive single-cell data analysis. Input requires a tsv seperated file [(please read detailed documentation here)](https://github.com/wtsi-hgi/yascp/tree/yascp_docs) with paths and if running in an genotype additional input is required to be provided in an input.nf file pointing to the vcf location. This pipeline is designed to be used any large scale single cell experiments.