Using SPIEC-EASI on transcriptomic data: plant/microbes

[GossypiumH]

Hi,

I wanted to know if it would be possible using Spiec-Easi to build networks of potentially interacting genes from transcriptomic data.

I explain: I have one dataset of plant genes that is from a plant transcriptomic survey. I used the same samples to retrieve the microbial transcriptome, so I have one dataset with the plant gene expressed and another with the microbial genes expressed in the same samples.

Would there be a problem to do an interkingdom analysis with those two dataset to see, what plant genes could be interacting with what microbial genes?

Cheers,