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MARSNet: Multiple efficient convolutional attention residual shrinkage networks to predict RBPs’ binding sites in RNA sequences


Introduction

In this study, a novel multi-efficient convolutional attention residual contraction network model, MARSNet, was constructed, in which the residual contraction network uses soft thresholding to remove noise data in RNA sequences and identify RBPs binding sites with high accuracy. MARSNet combines efficient channel attention (ECA) and convolutional block attention mechanism (CBAM). The combination of efficient channel attention (ECA) and convolutional block attention mechanism (CBAM) can automatically identify key information in RNA sequences.



Requirements

  • pytorch 1.8.1
  • python 3.8.5

datasets

Download and unzip training and test data:http://www.bioinf.uni-freiburg.de/Software/GraphProt/GraphProt_CLIP_sequences.tar.bz2


trian

python main.py 

detect motif

python Detect_motif.py 

Notice

If MARSNet does not converge in your datasets, you can replace Adam with SGD or RMSprop.

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