Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Drop exposure SNPs that fail harmonisation in MVMR #592

Open
wants to merge 1 commit into
base: master
Choose a base branch
from

Conversation

yatest
Copy link

@yatest yatest commented Feb 14, 2025

I believe this is a bug, however if it is a deliberate design choice then please ignore.

When harmonising the exposures with each other in MVMR, SNPs that are not present in all datasets are removed, as expected; however, SNPs that are palindromic/not inferable are not removed. This occurs in both mv_extract_exposures and mv_extract_exposures_local.

In mv_harmonise_data, SNPs that are palindromic/not inferable between the first exposure and outcome are correctly removed.

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
None yet
Projects
None yet
Development

Successfully merging this pull request may close these issues.

1 participant