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December Public Release Studies (#2097)
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* december release studies

* review fixes

* error fix

* error fix

* error fix

* updated the journal

* updates

* review updates

* update

* Update meta_study.txt

* Update meta_study.txt

* Update meta_study.txt

* Update meta_study.txt

* Update meta_study.txt

* Update meta_study.txt

* removed treat

* remove study

* fix error

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* Update meta_study.txt

* Update meta_study.txt

* Update meta_study.txt

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Co-authored-by: RAlhamad <[email protected]>
Co-authored-by: sbabyanusha <[email protected]>
Co-authored-by: sbabyanusha <[email protected]>
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6 changes: 6 additions & 0 deletions public/asclc_msk_2024/case_lists/cases_all.txt
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cancer_study_identifier: asclc_msk_2024
stable_id: asclc_msk_2024_all
case_list_name: All samples
case_list_description: All samples (31 samples)
case_list_category: all_cases_in_study
case_list_ids: P-0020333-T01-IM6 P-0039631-T04-IM6 P-0039208-T02-IM6 P-0013002-T01-IM5 P-0046178-T03-IM6 P-0038280-T02-IM6 P-0010928-T01-IM5 P-0004452-T02-IM7 P-0070307-T02-IM7 P-0026198-T01-IM6 P-0060626-T01-IM7 P-0002797-T01-IM3 P-0079554-T02-IM7 P-0045246-T01-IM6 P-0010928-T02-IM6 P-0039631-T05-IM6 P-0038280-T01-IM6 P-0046178-T02-IM6 P-0038280-T03-IM6 P-0026198-T02-IM6 P-0079554-T01-IM7 P-0038280-T05-IM7 P-0020429-T01-IM6 P-0004452-T01-IM5 P-0039208-T01-IM6 P-0070901-T01-IM7 P-0039631-T01-IM6 P-0044597-T01-IM6 P-0012905-T01-IM5 P-0004394-T01-IM5 P-0073997-T01-IM7
6 changes: 6 additions & 0 deletions public/asclc_msk_2024/case_lists/cases_cna.txt
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cancer_study_identifier: asclc_msk_2024
stable_id: asclc_msk_2024_cna
case_list_name: Samples with CNA data
case_list_description: Samples with CNA data (31 samples)
case_list_category: all_cases_with_cna_data
case_list_ids: P-0020333-T01-IM6 P-0039631-T04-IM6 P-0039208-T02-IM6 P-0013002-T01-IM5 P-0046178-T03-IM6 P-0038280-T02-IM6 P-0010928-T01-IM5 P-0004452-T02-IM7 P-0070307-T02-IM7 P-0026198-T01-IM6 P-0060626-T01-IM7 P-0002797-T01-IM3 P-0079554-T02-IM7 P-0045246-T01-IM6 P-0010928-T02-IM6 P-0039631-T05-IM6 P-0038280-T01-IM6 P-0046178-T02-IM6 P-0038280-T03-IM6 P-0026198-T02-IM6 P-0079554-T01-IM7 P-0038280-T05-IM7 P-0020429-T01-IM6 P-0004452-T01-IM5 P-0039208-T01-IM6 P-0070901-T01-IM7 P-0039631-T01-IM6 P-0044597-T01-IM6 P-0012905-T01-IM5 P-0004394-T01-IM5 P-0073997-T01-IM7
6 changes: 6 additions & 0 deletions public/asclc_msk_2024/case_lists/cases_cnaseq.txt
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cancer_study_identifier: asclc_msk_2024
stable_id: asclc_msk_2024_cnaseq
case_list_name: Samples with mutation and CNA data
case_list_description: Samples with mutation and CNA data (31 samples)
case_list_category: all_cases_with_mutation_and_cna_data
case_list_ids: P-0020333-T01-IM6 P-0039631-T04-IM6 P-0039208-T02-IM6 P-0013002-T01-IM5 P-0046178-T03-IM6 P-0038280-T02-IM6 P-0010928-T01-IM5 P-0004452-T02-IM7 P-0070307-T02-IM7 P-0026198-T01-IM6 P-0060626-T01-IM7 P-0002797-T01-IM3 P-0079554-T02-IM7 P-0045246-T01-IM6 P-0010928-T02-IM6 P-0039631-T05-IM6 P-0038280-T01-IM6 P-0046178-T02-IM6 P-0038280-T03-IM6 P-0026198-T02-IM6 P-0079554-T01-IM7 P-0038280-T05-IM7 P-0020429-T01-IM6 P-0004452-T01-IM5 P-0039208-T01-IM6 P-0070901-T01-IM7 P-0039631-T01-IM6 P-0044597-T01-IM6 P-0012905-T01-IM5 P-0004394-T01-IM5 P-0073997-T01-IM7
6 changes: 6 additions & 0 deletions public/asclc_msk_2024/case_lists/cases_mrna_seq_tpm.txt
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cancer_study_identifier: asclc_msk_2024
stable_id: asclc_msk_2024_rna_seq_mrna
case_list_name: Samples with mRNA data (RNA Seq TPM)
case_list_description: Samples with mRNA expression data (31 samples)
case_list_category: all_cases_with_mrna_rnaseq_data
case_list_ids: P-0020333-T01-IM6 P-0039631-T04-IM6 P-0039208-T02-IM6 P-0013002-T01-IM5 P-0046178-T03-IM6 P-0038280-T02-IM6 P-0010928-T01-IM5 P-0004452-T02-IM7 P-0070307-T02-IM7 P-0026198-T01-IM6 P-0060626-T01-IM7 P-0002797-T01-IM3 P-0079554-T02-IM7 P-0045246-T01-IM6 P-0010928-T02-IM6 P-0039631-T05-IM6 P-0038280-T01-IM6 P-0046178-T02-IM6 P-0038280-T03-IM6 P-0026198-T02-IM6 P-0079554-T01-IM7 P-0038280-T05-IM7 P-0020429-T01-IM6 P-0004452-T01-IM5 P-0039208-T01-IM6 P-0070901-T01-IM7 P-0039631-T01-IM6 P-0044597-T01-IM6 P-0012905-T01-IM5 P-0004394-T01-IM5 P-0073997-T01-IM7
6 changes: 6 additions & 0 deletions public/asclc_msk_2024/case_lists/cases_sequenced.txt
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cancer_study_identifier: asclc_msk_2024
stable_id: asclc_msk_2024_sequenced
case_list_name: Samples with mutation data
case_list_description: Samples with mutation data (31 samples)
case_list_category: all_cases_with_mutation_data
case_list_ids: P-0020333-T01-IM6 P-0039631-T04-IM6 P-0039208-T02-IM6 P-0013002-T01-IM5 P-0046178-T03-IM6 P-0038280-T02-IM6 P-0010928-T01-IM5 P-0004452-T02-IM7 P-0070307-T02-IM7 P-0026198-T01-IM6 P-0060626-T01-IM7 P-0002797-T01-IM3 P-0079554-T02-IM7 P-0045246-T01-IM6 P-0010928-T02-IM6 P-0039631-T05-IM6 P-0038280-T01-IM6 P-0046178-T02-IM6 P-0038280-T03-IM6 P-0026198-T02-IM6 P-0079554-T01-IM7 P-0038280-T05-IM7 P-0020429-T01-IM6 P-0004452-T01-IM5 P-0039208-T01-IM6 P-0070901-T01-IM7 P-0039631-T01-IM6 P-0044597-T01-IM6 P-0012905-T01-IM5 P-0004394-T01-IM5 P-0073997-T01-IM7
6 changes: 6 additions & 0 deletions public/asclc_msk_2024/case_lists/cases_sv.txt
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cancer_study_identifier: asclc_msk_2024
stable_id: asclc_msk_2024_sv
case_list_name: Samples with SV data
case_list_description: All samples with SV data (31 samples)
case_list_category: all_cases_with_sv_data
case_list_ids: P-0020333-T01-IM6 P-0039631-T04-IM6 P-0039208-T02-IM6 P-0013002-T01-IM5 P-0046178-T03-IM6 P-0038280-T02-IM6 P-0010928-T01-IM5 P-0004452-T02-IM7 P-0070307-T02-IM7 P-0026198-T01-IM6 P-0060626-T01-IM7 P-0002797-T01-IM3 P-0079554-T02-IM7 P-0045246-T01-IM6 P-0010928-T02-IM6 P-0039631-T05-IM6 P-0038280-T01-IM6 P-0046178-T02-IM6 P-0038280-T03-IM6 P-0026198-T02-IM6 P-0079554-T01-IM7 P-0038280-T05-IM7 P-0020429-T01-IM6 P-0004452-T01-IM5 P-0039208-T01-IM6 P-0070901-T01-IM7 P-0039631-T01-IM6 P-0044597-T01-IM6 P-0012905-T01-IM5 P-0004394-T01-IM5 P-0073997-T01-IM7
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4 changes: 4 additions & 0 deletions public/asclc_msk_2024/meta_clinical_patient.txt
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cancer_study_identifier: asclc_msk_2024
data_filename: data_clinical_patient.txt
genetic_alteration_type: CLINICAL
datatype: PATIENT_ATTRIBUTES
4 changes: 4 additions & 0 deletions public/asclc_msk_2024/meta_clinical_sample.txt
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cancer_study_identifier: asclc_msk_2024
data_filename: data_clinical_sample.txt
genetic_alteration_type: CLINICAL
datatype: SAMPLE_ATTRIBUTES
8 changes: 8 additions & 0 deletions public/asclc_msk_2024/meta_cna.txt
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cancer_study_identifier: asclc_msk_2024
genetic_alteration_type: COPY_NUMBER_ALTERATION
show_profile_in_analysis_tab: true
profile_name: Copy Number Alterations (MSK-IMPACT, HEME)
profile_description: Copy number alterations from targeted sequencing via MK-IMPACT on Illumina HiSeq sequencers.
datatype: DISCRETE
data_filename: data_cna.txt
stable_id: cna
9 changes: 9 additions & 0 deletions public/asclc_msk_2024/meta_cna_hg19_seg.txt
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cancer_study_identifier: asclc_msk_2024
data_filename: data_cna_hg19.seg
genetic_alteration_type: COPY_NUMBER_ALTERATION
datatype: SEG
show_profile_in_analysis_tab: FALSE
profile_name: Segment data values
profile_description: Somatic CNA data (copy number ratio from tumor samples minus ratio from matched normals)
reference_genome_id: hg19
description: segment data for asclc_msk_2024 study
4 changes: 4 additions & 0 deletions public/asclc_msk_2024/meta_gene_panel_matrix.txt
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cancer_study_identifier: asclc_msk_2024
genetic_alteration_type: GENE_PANEL_MATRIX
datatype: GENE_PANEL_MATRIX
data_filename: data_gene_panel_matrix.txt
9 changes: 9 additions & 0 deletions public/asclc_msk_2024/meta_mrna_seq_tpm.txt
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cancer_study_identifier: asclc_msk_2024
genetic_alteration_type: MRNA_EXPRESSION
datatype: CONTINUOUS
data_filename: data_mrna_seq_tpm.txt
stable_id: mrna_seq_tpm
show_profile_in_analysis_tab: FALSE
profile_description: mRNA Expression (TPM)
profile_name: mRNA expression normalized counts (TPM)
source_stable_id: rna_seq_mrna
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cancer_study_identifier: asclc_msk_2024
genetic_alteration_type: MRNA_EXPRESSION
datatype: Z-SCORE
stable_id: mrna_seq_tpm_all_sample_Zscores
show_profile_in_analysis_tab: true
profile_name: mRNA expression z-scores (TPM)
profile_description: Expression levels z-scores (TPM)
data_filename: data_mrna_seq_tpm_zscores_ref_all_samples.txt
8 changes: 8 additions & 0 deletions public/asclc_msk_2024/meta_mutations.txt
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cancer_study_identifier: asclc_msk_2024
genetic_alteration_type: MUTATION_EXTENDED
datatype: MAF
stable_id: mutations
show_profile_in_analysis_tab: true
profile_description: Somatic mutation data from targeted sequencing of 31 lung cancer samples
profile_name: Mutations
data_filename: data_mutations.txt
6 changes: 6 additions & 0 deletions public/asclc_msk_2024/meta_study.txt
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cancer_study_identifier: asclc_msk_2024
type_of_cancer: lung
name: Atypical Small Cell Lung Cancer (MSK, Cancer Discov 2024)
description: Targeted sequencing of 31 atypical small cell lung cancers lacking RB1 and TP53 co-inactivation and their matched normals via MSK-IMPACT, including structural variant analysis via whole-genome sequencing. This data is available under the <a href="https://creativecommons.org/licenses/by-nc-nd/4.0/deed.en">Creative Commons BY-NC-ND 4.0 license</a>.
pmid: 39185963
citation: Rekhtman N et al. Cancer Discov 2024
8 changes: 8 additions & 0 deletions public/asclc_msk_2024/meta_sv.txt
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cancer_study_identifier: asclc_msk_2024
data_filename: data_sv.txt
stable_id: structural_variants
genetic_alteration_type: STRUCTURAL_VARIANT
datatype: SV
show_profile_in_analysis_tab: TRUE
profile_name: Structural Variants (WGS)
profile_description: Structural variant data through whole-genome sequencing.
4 changes: 4 additions & 0 deletions public/asclc_msk_2024/meta_timeline_diagnosistxt.txt
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cancer_study_identifier: asclc_msk_2024
data_filename: data_timeline_diagnosis.txt
genetic_alteration_type: CLINICAL
datatype: TIMELINE
4 changes: 4 additions & 0 deletions public/asclc_msk_2024/meta_timeline_pdl1.txt
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cancer_study_identifier: asclc_msk_2024
data_filename: data_timeline_pdl1.txt
genetic_alteration_type: CLINICAL
datatype: TIMELINE
4 changes: 4 additions & 0 deletions public/asclc_msk_2024/meta_timeline_prior_meds.txt
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cancer_study_identifier: asclc_msk_2024
data_filename: data_timeline_prior_meds.txt
genetic_alteration_type: CLINICAL
datatype: TIMELINE
4 changes: 4 additions & 0 deletions public/asclc_msk_2024/meta_timeline_radiation.txt
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cancer_study_identifier: asclc_msk_2024
data_filename: data_timeline_radiation.txt
genetic_alteration_type: CLINICAL
datatype: TIMELINE
4 changes: 4 additions & 0 deletions public/asclc_msk_2024/meta_timeline_specimen.txt
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cancer_study_identifier: asclc_msk_2024
data_filename: data_timeline_specimen.txt
genetic_alteration_type: CLINICAL
datatype: TIMELINE
4 changes: 4 additions & 0 deletions public/asclc_msk_2024/meta_timeline_specimen_surgery.txt
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cancer_study_identifier: asclc_msk_2024
data_filename: data_timeline_specimen_surgery.txt
genetic_alteration_type: CLINICAL
datatype: TIMELINE
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cancer_study_identifier: asclc_msk_2024
data_filename: data_timeline_surgery.txt
genetic_alteration_type: CLINICAL
datatype: TIMELINE
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cancer_study_identifier: asclc_msk_2024
data_filename: data_timeline_timeline_follow_up.txt
genetic_alteration_type: CLINICAL
datatype: TIMELINE
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cancer_study_identifier: asclc_msk_2024
data_filename: data_timeline_treatment.txt
genetic_alteration_type: CLINICAL
datatype: TIMELINE
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cancer_study_identifier: asclc_msk_2024
data_filename: data_timeline_tumor_sites.txt
genetic_alteration_type: CLINICAL
datatype: TIMELINE
28 changes: 28 additions & 0 deletions public/brca_dfci_2020/README.md
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Study Curation and Transformation README

General information

Curator name: Chizobam Ugboaja (Georgetown University 2024)
Reference publication: 32404308
Reference genome used: GRCh37

Clinical Data

Supplementary file: (Supplementary Table S1)
Supplementary table title: (Clinical Samples Included in Landscape Analysis) Sample size: (59 samples and 58 patients)

Timeline Data
Supplementary file: (Supplementary Table S1)
Prescription/treatment data obtained from clinical file

Mutation Data

Supplementary file: (Supplementary Table S3, Sheet 1)
Supplementary table title : (Exome and mutational information)
Reference genome: (GRCh37)

Segmented Data
Supplementary file: (Supplementary Table S3, Sheet 2)
Supplementary table title : (CNVs - segment level)

* NOTE: data pending from author include CNA, enrichment, and survival analysis*
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cancer_study_identifier: brca_dfci_2020
stable_id: brca_dfci_2020_all
case_list_name: All samples
case_list_description: All samples (59 samples)
case_list_category: all_cases_in_study
case_list_ids: 177_Prospective1 185_T1 191_T1 195_T1 260_T1 290_T2 292_T1 294_T2 295_T1 299_T1 303_T1 306_T1 307_T1 314_T1 315_T1 327_T1 329_T1 330_T1 331_T1 333_T1 338_T1 346_T1 349_T1 350_T1 357_T1 358_T1 361_T1 366_T2 372_T1 376_T2 381_T1 383_T1 385_T1 386_T1 387_T1 391_T1 394_T2 397_T1 398_T1 401_T1 408_T1A 408_T1B 430_T1 434_T1 452_T2 459_Archival1 473_T1 496_T1 509_T1 515_T1 516_T1 532_T1 535_T1 538_T1 552_T1 567_T1 568_T1 606_T1 614_T1
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cancer_study_identifier: brca_dfci_2020
stable_id: brca_dfci_2020_sequenced
case_list_name: Samples with mutation data
case_list_description: Samples with mutation data (59 samples)
case_list_category: all_cases_with_mutation_data
case_list_ids: 177_Prospective1 185_T1 191_T1 195_T1 260_T1 290_T2 292_T1 294_T2 295_T1 299_T1 303_T1 306_T1 307_T1 314_T1 315_T1 327_T1 329_T1 330_T1 331_T1 333_T1 338_T1 346_T1 349_T1 350_T1 357_T1 358_T1 361_T1 366_T2 372_T1 376_T2 381_T1 383_T1 385_T1 386_T1 387_T1 391_T1 394_T2 397_T1 398_T1 401_T1 408_T1A 408_T1B 430_T1 434_T1 452_T2 459_Archival1 473_T1 496_T1 509_T1 515_T1 516_T1 532_T1 535_T1 538_T1 552_T1 567_T1 568_T1 606_T1 614_T1
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cancer_study_identifier: brca_dfci_2020genetic_alteration_type: CLINICALdatatype: PATIENT_ATTRIBUTESdata_filename: data_clinical_patient.txt
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cancer_study_identifier: brca_dfci_2020genetic_alteration_type: CLINICALdatatype: SAMPLE_ATTRIBUTESdata_filename: data_clinical_sample.txt
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cancer_study_identifier: brca_dfci_2020data_filename: data_mutations.txtstable_id: mutationsgenetic_alteration_type: MUTATION_EXTENDEDdatatype: MAFshow_profile_in_analysis_tab: TRUEprofile_name: Mutationsprofile_description: Mutation data from whole exome sequencing.
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type_of_cancer: brcacancer_study_identifier: brca_dfci_2020name: Metastatic Breast Cancer (DFCI, Cancer Discov 2020)description: Whole-exome sequencing of 59 CDK4/6i exposed metastatic breast cancer tumors and their matched normals.citation: Wander, Seth A et al. Cancer Discov 2020pmid: 32404308
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4 changes: 4 additions & 0 deletions public/hcc_msk_2024/meta_clinical_patient.txt
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cancer_study_identifier: hcc_msk_2024
data_filename: data_clinical_patient.txt
genetic_alteration_type: CLINICAL
datatype: PATIENT_ATTRIBUTES
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cancer_study_identifier: hcc_msk_2024
data_filename: data_clinical_sample.txt
genetic_alteration_type: CLINICAL
datatype: SAMPLE_ATTRIBUTES
8 changes: 8 additions & 0 deletions public/hcc_msk_2024/meta_cna.txt
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cancer_study_identifier: hcc_msk_2024
genetic_alteration_type: COPY_NUMBER_ALTERATION
show_profile_in_analysis_tab: true
profile_name: Copy Number Alterations (MSK-IMPACT, HEME)
profile_description: Copy number alterations from targeted sequencing via MK-IMPACT on Illumina HiSeq sequencers.
datatype: DISCRETE
data_filename: data_cna.txt
stable_id: cna
9 changes: 9 additions & 0 deletions public/hcc_msk_2024/meta_cna_hg19_seg.txt
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cancer_study_identifier: hcc_msk_2024
data_filename: data_cna_hg19.seg
genetic_alteration_type: COPY_NUMBER_ALTERATION
datatype: SEG
show_profile_in_analysis_tab: FALSE
profile_name: Segment data values
profile_description: Somatic CNA data (copy number ratio from tumor samples minus ratio from matched normals)
reference_genome_id: hg19
description: segment data for asclc_msk_2024 study
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cancer_study_identifier: hcc_msk_2024
genetic_alteration_type: GENE_PANEL_MATRIX
datatype: GENE_PANEL_MATRIX
data_filename: data_gene_panel_matrix.txt
8 changes: 8 additions & 0 deletions public/hcc_msk_2024/meta_mutations.txt
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cancer_study_identifier: hcc_msk_2024
genetic_alteration_type: MUTATION_EXTENDED
datatype: MAF
stable_id: mutations
show_profile_in_analysis_tab: true
profile_description: Somatic mutation data from targeted sequencing samples.
profile_name: Mutations
data_filename: data_mutations.txt
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