index.html

<!DOCTYPE html>
<html>
<head><meta charset="utf-8" />
<title>Userdata_script12</title><script src="https://cdnjs.cloudflare.com/ajax/libs/require.js/2.1.10/require.min.js"></script>
<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/2.0.3/jquery.min.js"></script>

<style type="text/css">
    /*!
*
* Twitter Bootstrap
*
*/
/*!
 * Bootstrap v3.3.7 (http://getbootstrap.com)
 * Copyright 2011-2016 Twitter, Inc.
 * Licensed under MIT (https://github.com/twbs/bootstrap/blob/master/LICENSE)
 */
/*! normalize.css v3.0.3 | MIT License | github.com/necolas/normalize.css */
html {
  font-family: sans-serif;
  -ms-text-size-adjust: 100%;
  -webkit-text-size-adjust: 100%;
}
body {
  margin: 0;
}
article,
aside,
details,
figcaption,
figure,
footer,
header,
hgroup,
main,
menu,
nav,
section,
summary {
  display: block;
}
audio,
canvas,
progress,
video {
  display: inline-block;
  vertical-align: baseline;
}
audio:not([controls]) {
  display: none;
  height: 0;
}
[hidden],
template {
  display: none;
}
a {
  background-color: transparent;
}
a:active,
a:hover {
  outline: 0;
}
abbr[title] {
  border-bottom: 1px dotted;
}
b,
strong {
  font-weight: bold;
}
dfn {
  font-style: italic;
}
h1 {
  font-size: 2em;
  margin: 0.67em 0;
}
mark {
  background: #ff0;
  color: #000;
}
small {
  font-size: 80%;
}
sub,
sup {
  font-size: 75%;
  line-height: 0;
  position: relative;
  vertical-align: baseline;
}
sup {
  top: -0.5em;
}
sub {
  bottom: -0.25em;
}
img {
  border: 0;
}
svg:not(:root) {
  overflow: hidden;
}
figure {
  margin: 1em 40px;
}
hr {
  box-sizing: content-box;
  height: 0;
}
pre {
  overflow: auto;
}
code,
kbd,
pre,
samp {
  font-family: monospace, monospace;
  font-size: 1em;
}
button,
input,
optgroup,
select,
textarea {
  color: inherit;
  font: inherit;
  margin: 0;
}
button {
  overflow: visible;
}
button,
select {
  text-transform: none;
}
button,
html input[type="button"],
input[type="reset"],
input[type="submit"] {
  -webkit-appearance: button;
  cursor: pointer;
}
button[disabled],
html input[disabled] {
  cursor: default;
}
button::-moz-focus-inner,
input::-moz-focus-inner {
  border: 0;
  padding: 0;
}
input {
  line-height: normal;
}
input[type="checkbox"],
input[type="radio"] {
  box-sizing: border-box;
  padding: 0;
}
input[type="number"]::-webkit-inner-spin-button,
input[type="number"]::-webkit-outer-spin-button {
  height: auto;
}
input[type="search"] {
  -webkit-appearance: textfield;
  box-sizing: content-box;
}
input[type="search"]::-webkit-search-cancel-button,
input[type="search"]::-webkit-search-decoration {
  -webkit-appearance: none;
}
fieldset {
  border: 1px solid #c0c0c0;
  margin: 0 2px;
  padding: 0.35em 0.625em 0.75em;
}
legend {
  border: 0;
  padding: 0;
}
textarea {
  overflow: auto;
}
optgroup {
  font-weight: bold;
}
table {
  border-collapse: collapse;
  border-spacing: 0;
}
td,
th {
  padding: 0;
}
/*! Source: https://github.com/h5bp/html5-boilerplate/blob/master/src/css/main.css */
@media print {
  *,
  *:before,
  *:after {
    background: transparent !important;
    color: #000 !important;
    box-shadow: none !important;
    text-shadow: none !important;
  }
  a,
  a:visited {
    text-decoration: underline;
  }
  a[href]:after {
    content: " (" attr(href) ")";
  }
  abbr[title]:after {
    content: " (" attr(title) ")";
  }
  a[href^="#"]:after,
  a[href^="javascript:"]:after {
    content: "";
  }
  pre,
  blockquote {
    border: 1px solid #999;
    page-break-inside: avoid;
  }
  thead {
    display: table-header-group;
  }
  tr,
  img {
    page-break-inside: avoid;
  }
  img {
    max-width: 100% !important;
  }
  p,
  h2,
  h3 {
    orphans: 3;
    widows: 3;
  }
  h2,
  h3 {
    page-break-after: avoid;
  }
  .navbar {
    display: none;
  }
  .btn > .caret,
  .dropup > .btn > .caret {
    border-top-color: #000 !important;
  }
  .label {
    border: 1px solid #000;
  }
  .table {
    border-collapse: collapse !important;
  }
  .table td,
  .table th {
    background-color: #fff !important;
  }
  .table-bordered th,
  .table-bordered td {
    border: 1px solid #ddd !important;
  }
}
@font-face {
  font-family: 'Glyphicons Halflings';
  src: url('../components/bootstrap/fonts/glyphicons-halflings-regular.eot');
  src: url('../components/bootstrap/fonts/glyphicons-halflings-regular.eot?#iefix') format('embedded-opentype'), url('../components/bootstrap/fonts/glyphicons-halflings-regular.woff2') format('woff2'), url('../components/bootstrap/fonts/glyphicons-halflings-regular.woff') format('woff'), url('../components/bootstrap/fonts/glyphicons-halflings-regular.ttf') format('truetype'), url('../components/bootstrap/fonts/glyphicons-halflings-regular.svg#glyphicons_halflingsregular') format('svg');
}
.glyphicon {
  position: relative;
  top: 1px;
  display: inline-block;
  font-family: 'Glyphicons Halflings';
  font-style: normal;
  font-weight: normal;
  line-height: 1;
  -webkit-font-smoothing: antialiased;
  -moz-osx-font-smoothing: grayscale;
}
.glyphicon-asterisk:before {
  content: "\002a";
}
.glyphicon-plus:before {
  content: "\002b";
}
.glyphicon-euro:before,
.glyphicon-eur:before {
  content: "\20ac";
}
.glyphicon-minus:before {
  content: "\2212";
}
.glyphicon-cloud:before {
  content: "\2601";
}
.glyphicon-envelope:before {
  content: "\2709";
}
.glyphicon-pencil:before {
  content: "\270f";
}
.glyphicon-glass:before {
  content: "\e001";
}
.glyphicon-music:before {
  content: "\e002";
}
.glyphicon-search:before {
  content: "\e003";
}
.glyphicon-heart:before {
  content: "\e005";
}
.glyphicon-star:before {
  content: "\e006";
}
.glyphicon-star-empty:before {
  content: "\e007";
}
.glyphicon-user:before {
  content: "\e008";
}
.glyphicon-film:before {
  content: "\e009";
}
.glyphicon-th-large:before {
  content: "\e010";
}
.glyphicon-th:before {
  content: "\e011";
}
.glyphicon-th-list:before {
  content: "\e012";
}
.glyphicon-ok:before {
  content: "\e013";
}
.glyphicon-remove:before {
  content: "\e014";
}
.glyphicon-zoom-in:before {
  content: "\e015";
}
.glyphicon-zoom-out:before {
  content: "\e016";
}
.glyphicon-off:before {
  content: "\e017";
}
.glyphicon-signal:before {
  content: "\e018";
}
.glyphicon-cog:before {
  content: "\e019";
}
.glyphicon-trash:before {
  content: "\e020";
}
.glyphicon-home:before {
  content: "\e021";
}
.glyphicon-file:before {
  content: "\e022";
}
.glyphicon-time:before {
  content: "\e023";
}
.glyphicon-road:before {
  content: "\e024";
}
.glyphicon-download-alt:before {
  content: "\e025";
}
.glyphicon-download:before {
  content: "\e026";
}
.glyphicon-upload:before {
  content: "\e027";
}
.glyphicon-inbox:before {
  content: "\e028";
}
.glyphicon-play-circle:before {
  content: "\e029";
}
.glyphicon-repeat:before {
  content: "\e030";
}
.glyphicon-refresh:before {
  content: "\e031";
}
.glyphicon-list-alt:before {
  content: "\e032";
}
.glyphicon-lock:before {
  content: "\e033";
}
.glyphicon-flag:before {
  content: "\e034";
}
.glyphicon-headphones:before {
  content: "\e035";
}
.glyphicon-volume-off:before {
  content: "\e036";
}
.glyphicon-volume-down:before {
  content: "\e037";
}
.glyphicon-volume-up:before {
  content: "\e038";
}
.glyphicon-qrcode:before {
  content: "\e039";
}
.glyphicon-barcode:before {
  content: "\e040";
}
.glyphicon-tag:before {
  content: "\e041";
}
.glyphicon-tags:before {
  content: "\e042";
}
.glyphicon-book:before {
  content: "\e043";
}
.glyphicon-bookmark:before {
  content: "\e044";
}
.glyphicon-print:before {
  content: "\e045";
}
.glyphicon-camera:before {
  content: "\e046";
}
.glyphicon-font:before {
  content: "\e047";
}
.glyphicon-bold:before {
  content: "\e048";
}
.glyphicon-italic:before {
  content: "\e049";
}
.glyphicon-text-height:before {
  content: "\e050";
}
.glyphicon-text-width:before {
  content: "\e051";
}
.glyphicon-align-left:before {
  content: "\e052";
}
.glyphicon-align-center:before {
  content: "\e053";
}
.glyphicon-align-right:before {
  content: "\e054";
}
.glyphicon-align-justify:before {
  content: "\e055";
}
.glyphicon-list:before {
  content: "\e056";
}
.glyphicon-indent-left:before {
  content: "\e057";
}
.glyphicon-indent-right:before {
  content: "\e058";
}
.glyphicon-facetime-video:before {
  content: "\e059";
}
.glyphicon-picture:before {
  content: "\e060";
}
.glyphicon-map-marker:before {
  content: "\e062";
}
.glyphicon-adjust:before {
  content: "\e063";
}
.glyphicon-tint:before {
  content: "\e064";
}
.glyphicon-edit:before {
  content: "\e065";
}
.glyphicon-share:before {
  content: "\e066";
}
.glyphicon-check:before {
  content: "\e067";
}
.glyphicon-move:before {
  content: "\e068";
}
.glyphicon-step-backward:before {
  content: "\e069";
}
.glyphicon-fast-backward:before {
  content: "\e070";
}
.glyphicon-backward:before {
  content: "\e071";
}
.glyphicon-play:before {
  content: "\e072";
}
.glyphicon-pause:before {
  content: "\e073";
}
.glyphicon-stop:before {
  content: "\e074";
}
.glyphicon-forward:before {
  content: "\e075";
}
.glyphicon-fast-forward:before {
  content: "\e076";
}
.glyphicon-step-forward:before {
  content: "\e077";
}
.glyphicon-eject:before {
  content: "\e078";
}
.glyphicon-chevron-left:before {
  content: "\e079";
}
.glyphicon-chevron-right:before {
  content: "\e080";
}
.glyphicon-plus-sign:before {
  content: "\e081";
}
.glyphicon-minus-sign:before {
  content: "\e082";
}
.glyphicon-remove-sign:before {
  content: "\e083";
}
.glyphicon-ok-sign:before {
  content: "\e084";
}
.glyphicon-question-sign:before {
  content: "\e085";
}
.glyphicon-info-sign:before {
  content: "\e086";
}
.glyphicon-screenshot:before {
  content: "\e087";
}
.glyphicon-remove-circle:before {
  content: "\e088";
}
.glyphicon-ok-circle:before {
  content: "\e089";
}
.glyphicon-ban-circle:before {
  content: "\e090";
}
.glyphicon-arrow-left:before {
  content: "\e091";
}
.glyphicon-arrow-right:before {
  content: "\e092";
}
.glyphicon-arrow-up:before {
  content: "\e093";
}
.glyphicon-arrow-down:before {
  content: "\e094";
}
.glyphicon-share-alt:before {
  content: "\e095";
}
.glyphicon-resize-full:before {
  content: "\e096";
}
.glyphicon-resize-small:before {
  content: "\e097";
}
.glyphicon-exclamation-sign:before {
  content: "\e101";
}
.glyphicon-gift:before {
  content: "\e102";
}
.glyphicon-leaf:before {
  content: "\e103";
}
.glyphicon-fire:before {
  content: "\e104";
}
.glyphicon-eye-open:before {
  content: "\e105";
}
.glyphicon-eye-close:before {
  content: "\e106";
}
.glyphicon-warning-sign:before {
  content: "\e107";
}
.glyphicon-plane:before {
  content: "\e108";
}
.glyphicon-calendar:before {
  content: "\e109";
}
.glyphicon-random:before {
  content: "\e110";
}
.glyphicon-comment:before {
  content: "\e111";
}
.glyphicon-magnet:before {
  content: "\e112";
}
.glyphicon-chevron-up:before {
  content: "\e113";
}
.glyphicon-chevron-down:before {
  content: "\e114";
}
.glyphicon-retweet:before {
  content: "\e115";
}
.glyphicon-shopping-cart:before {
  content: "\e116";
}
.glyphicon-folder-close:before {
  content: "\e117";
}
.glyphicon-folder-open:before {
  content: "\e118";
}
.glyphicon-resize-vertical:before {
  content: "\e119";
}
.glyphicon-resize-horizontal:before {
  content: "\e120";
}
.glyphicon-hdd:before {
  content: "\e121";
}
.glyphicon-bullhorn:before {
  content: "\e122";
}
.glyphicon-bell:before {
  content: "\e123";
}
.glyphicon-certificate:before {
  content: "\e124";
}
.glyphicon-thumbs-up:before {
  content: "\e125";
}
.glyphicon-thumbs-down:before {
  content: "\e126";
}
.glyphicon-hand-right:before {
  content: "\e127";
}
.glyphicon-hand-left:before {
  content: "\e128";
}
.glyphicon-hand-up:before {
  content: "\e129";
}
.glyphicon-hand-down:before {
  content: "\e130";
}
.glyphicon-circle-arrow-right:before {
  content: "\e131";
}
.glyphicon-circle-arrow-left:before {
  content: "\e132";
}
.glyphicon-circle-arrow-up:before {
  content: "\e133";
}
.glyphicon-circle-arrow-down:before {
  content: "\e134";
}
.glyphicon-globe:before {
  content: "\e135";
}
.glyphicon-wrench:before {
  content: "\e136";
}
.glyphicon-tasks:before {
  content: "\e137";
}
.glyphicon-filter:before {
  content: "\e138";
}
.glyphicon-briefcase:before {
  content: "\e139";
}
.glyphicon-fullscreen:before {
  content: "\e140";
}
.glyphicon-dashboard:before {
  content: "\e141";
}
.glyphicon-paperclip:before {
  content: "\e142";
}
.glyphicon-heart-empty:before {
  content: "\e143";
}
.glyphicon-link:before {
  content: "\e144";
}
.glyphicon-phone:before {
  content: "\e145";
}
.glyphicon-pushpin:before {
  content: "\e146";
}
.glyphicon-usd:before {
  content: "\e148";
}
.glyphicon-gbp:before {
  content: "\e149";
}
.glyphicon-sort:before {
  content: "\e150";
}
.glyphicon-sort-by-alphabet:before {
  content: "\e151";
}
.glyphicon-sort-by-alphabet-alt:before {
  content: "\e152";
}
.glyphicon-sort-by-order:before {
  content: "\e153";
}
.glyphicon-sort-by-order-alt:before {
  content: "\e154";
}
.glyphicon-sort-by-attributes:before {
  content: "\e155";
}
.glyphicon-sort-by-attributes-alt:before {
  content: "\e156";
}
.glyphicon-unchecked:before {
  content: "\e157";
}
.glyphicon-expand:before {
  content: "\e158";
}
.glyphicon-collapse-down:before {
  content: "\e159";
}
.glyphicon-collapse-up:before {
  content: "\e160";
}
.glyphicon-log-in:before {
  content: "\e161";
}
.glyphicon-flash:before {
  content: "\e162";
}
.glyphicon-log-out:before {
  content: "\e163";
}
.glyphicon-new-window:before {
  content: "\e164";
}
.glyphicon-record:before {
  content: "\e165";
}
.glyphicon-save:before {
  content: "\e166";
}
.glyphicon-open:before {
  content: "\e167";
}
.glyphicon-saved:before {
  content: "\e168";
}
.glyphicon-import:before {
  content: "\e169";
}
.glyphicon-export:before {
  content: "\e170";
}
.glyphicon-send:before {
  content: "\e171";
}
.glyphicon-floppy-disk:before {
  content: "\e172";
}
.glyphicon-floppy-saved:before {
  content: "\e173";
}
.glyphicon-floppy-remove:before {
  content: "\e174";
}
.glyphicon-floppy-save:before {
  content: "\e175";
}
.glyphicon-floppy-open:before {
  content: "\e176";
}
.glyphicon-credit-card:before {
  content: "\e177";
}
.glyphicon-transfer:before {
  content: "\e178";
}
.glyphicon-cutlery:before {
  content: "\e179";
}
.glyphicon-header:before {
  content: "\e180";
}
.glyphicon-compressed:before {
  content: "\e181";
}
.glyphicon-earphone:before {
  content: "\e182";
}
.glyphicon-phone-alt:before {
  content: "\e183";
}
.glyphicon-tower:before {
  content: "\e184";
}
.glyphicon-stats:before {
  content: "\e185";
}
.glyphicon-sd-video:before {
  content: "\e186";
}
.glyphicon-hd-video:before {
  content: "\e187";
}
.glyphicon-subtitles:before {
  content: "\e188";
}
.glyphicon-sound-stereo:before {
  content: "\e189";
}
.glyphicon-sound-dolby:before {
  content: "\e190";
}
.glyphicon-sound-5-1:before {
  content: "\e191";
}
.glyphicon-sound-6-1:before {
  content: "\e192";
}
.glyphicon-sound-7-1:before {
  content: "\e193";
}
.glyphicon-copyright-mark:before {
  content: "\e194";
}
.glyphicon-registration-mark:before {
  content: "\e195";
}
.glyphicon-cloud-download:before {
  content: "\e197";
}
.glyphicon-cloud-upload:before {
  content: "\e198";
}
.glyphicon-tree-conifer:before {
  content: "\e199";
}
.glyphicon-tree-deciduous:before {
  content: "\e200";
}
.glyphicon-cd:before {
  content: "\e201";
}
.glyphicon-save-file:before {
  content: "\e202";
}
.glyphicon-open-file:before {
  content: "\e203";
}
.glyphicon-level-up:before {
  content: "\e204";
}
.glyphicon-copy:before {
  content: "\e205";
}
.glyphicon-paste:before {
  content: "\e206";
}
.glyphicon-alert:before {
  content: "\e209";
}
.glyphicon-equalizer:before {
  content: "\e210";
}
.glyphicon-king:before {
  content: "\e211";
}
.glyphicon-queen:before {
  content: "\e212";
}
.glyphicon-pawn:before {
  content: "\e213";
}
.glyphicon-bishop:before {
  content: "\e214";
}
.glyphicon-knight:before {
  content: "\e215";
}
.glyphicon-baby-formula:before {
  content: "\e216";
}
.glyphicon-tent:before {
  content: "\26fa";
}
.glyphicon-blackboard:before {
  content: "\e218";
}
.glyphicon-bed:before {
  content: "\e219";
}
.glyphicon-apple:before {
  content: "\f8ff";
}
.glyphicon-erase:before {
  content: "\e221";
}
.glyphicon-hourglass:before {
  content: "\231b";
}
.glyphicon-lamp:before {
  content: "\e223";
}
.glyphicon-duplicate:before {
  content: "\e224";
}
.glyphicon-piggy-bank:before {
  content: "\e225";
}
.glyphicon-scissors:before {
  content: "\e226";
}
.glyphicon-bitcoin:before {
  content: "\e227";
}
.glyphicon-btc:before {
  content: "\e227";
}
.glyphicon-xbt:before {
  content: "\e227";
}
.glyphicon-yen:before {
  content: "\00a5";
}
.glyphicon-jpy:before {
  content: "\00a5";
}
.glyphicon-ruble:before {
  content: "\20bd";
}
.glyphicon-rub:before {
  content: "\20bd";
}
.glyphicon-scale:before {
  content: "\e230";
}
.glyphicon-ice-lolly:before {
  content: "\e231";
}
.glyphicon-ice-lolly-tasted:before {
  content: "\e232";
}
.glyphicon-education:before {
  content: "\e233";
}
.glyphicon-option-horizontal:before {
  content: "\e234";
}
.glyphicon-option-vertical:before {
  content: "\e235";
}
.glyphicon-menu-hamburger:before {
  content: "\e236";
}
.glyphicon-modal-window:before {
  content: "\e237";
}
.glyphicon-oil:before {
  content: "\e238";
}
.glyphicon-grain:before {
  content: "\e239";
}
.glyphicon-sunglasses:before {
  content: "\e240";
}
.glyphicon-text-size:before {
  content: "\e241";
}
.glyphicon-text-color:before {
  content: "\e242";
}
.glyphicon-text-background:before {
  content: "\e243";
}
.glyphicon-object-align-top:before {
  content: "\e244";
}
.glyphicon-object-align-bottom:before {
  content: "\e245";
}
.glyphicon-object-align-horizontal:before {
  content: "\e246";
}
.glyphicon-object-align-left:before {
  content: "\e247";
}
.glyphicon-object-align-vertical:before {
  content: "\e248";
}
.glyphicon-object-align-right:before {
  content: "\e249";
}
.glyphicon-triangle-right:before {
  content: "\e250";
}
.glyphicon-triangle-left:before {
  content: "\e251";
}
.glyphicon-triangle-bottom:before {
  content: "\e252";
}
.glyphicon-triangle-top:before {
  content: "\e253";
}
.glyphicon-console:before {
  content: "\e254";
}
.glyphicon-superscript:before {
  content: "\e255";
}
.glyphicon-subscript:before {
  content: "\e256";
}
.glyphicon-menu-left:before {
  content: "\e257";
}
.glyphicon-menu-right:before {
  content: "\e258";
}
.glyphicon-menu-down:before {
  content: "\e259";
}
.glyphicon-menu-up:before {
  content: "\e260";
}
* {
  -webkit-box-sizing: border-box;
  -moz-box-sizing: border-box;
  box-sizing: border-box;
}
*:before,
*:after {
  -webkit-box-sizing: border-box;
  -moz-box-sizing: border-box;
  box-sizing: border-box;
}
html {
  font-size: 10px;
  -webkit-tap-highlight-color: rgba(0, 0, 0, 0);
}
body {
  font-family: "Helvetica Neue", Helvetica, Arial, sans-serif;
  font-size: 13px;
  line-height: 1.42857143;
  color: #000;
  background-color: #fff;
}
input,
button,
select,
textarea {
  font-family: inherit;
  font-size: inherit;
  line-height: inherit;
}
a {
  color: #337ab7;
  text-decoration: none;
}
a:hover,
a:focus {
  color: #23527c;
  text-decoration: underline;
}
a:focus {
  outline: 5px auto -webkit-focus-ring-color;
  outline-offset: -2px;
}
figure {
  margin: 0;
}
img {
  vertical-align: middle;
}
.img-responsive,
.thumbnail > img,
.thumbnail a > img,
.carousel-inner > .item > img,
.carousel-inner > .item > a > img {
  display: block;
  max-width: 100%;
  height: auto;
}
.img-rounded {
  border-radius: 3px;
}
.img-thumbnail {
  padding: 4px;
  line-height: 1.42857143;
  background-color: #fff;
  border: 1px solid #ddd;
  border-radius: 2px;
  -webkit-transition: all 0.2s ease-in-out;
  -o-transition: all 0.2s ease-in-out;
  transition: all 0.2s ease-in-out;
  display: inline-block;
  max-width: 100%;
  height: auto;
}
.img-circle {
  border-radius: 50%;
}
hr {
  margin-top: 18px;
  margin-bottom: 18px;
  border: 0;
  border-top: 1px solid #eeeeee;
}
.sr-only {
  position: absolute;
  width: 1px;
  height: 1px;
  margin: -1px;
  padding: 0;
  overflow: hidden;
  clip: rect(0, 0, 0, 0);
  border: 0;
}
.sr-only-focusable:active,
.sr-only-focusable:focus {
  position: static;
  width: auto;
  height: auto;
  margin: 0;
  overflow: visible;
  clip: auto;
}
[role="button"] {
  cursor: pointer;
}
h1,
h2,
h3,
h4,
h5,
h6,
.h1,
.h2,
.h3,
.h4,
.h5,
.h6 {
  font-family: inherit;
  font-weight: 500;
  line-height: 1.1;
  color: inherit;
}
h1 small,
h2 small,
h3 small,
h4 small,
h5 small,
h6 small,
.h1 small,
.h2 small,
.h3 small,
.h4 small,
.h5 small,
.h6 small,
h1 .small,
h2 .small,
h3 .small,
h4 .small,
h5 .small,
h6 .small,
.h1 .small,
.h2 .small,
.h3 .small,
.h4 .small,
.h5 .small,
.h6 .small {
  font-weight: normal;
  line-height: 1;
  color: #777777;
}
h1,
.h1,
h2,
.h2,
h3,
.h3 {
  margin-top: 18px;
  margin-bottom: 9px;
}
h1 small,
.h1 small,
h2 small,
.h2 small,
h3 small,
.h3 small,
h1 .small,
.h1 .small,
h2 .small,
.h2 .small,
h3 .small,
.h3 .small {
  font-size: 65%;
}
h4,
.h4,
h5,
.h5,
h6,
.h6 {
  margin-top: 9px;
  margin-bottom: 9px;
}
h4 small,
.h4 small,
h5 small,
.h5 small,
h6 small,
.h6 small,
h4 .small,
.h4 .small,
h5 .small,
.h5 .small,
h6 .small,
.h6 .small {
  font-size: 75%;
}
h1,
.h1 {
  font-size: 33px;
}
h2,
.h2 {
  font-size: 27px;
}
h3,
.h3 {
  font-size: 23px;
}
h4,
.h4 {
  font-size: 17px;
}
h5,
.h5 {
  font-size: 13px;
}
h6,
.h6 {
  font-size: 12px;
}
p {
  margin: 0 0 9px;
}
.lead {
  margin-bottom: 18px;
  font-size: 14px;
  font-weight: 300;
  line-height: 1.4;
}
@media (min-width: 768px) {
  .lead {
    font-size: 19.5px;
  }
}
small,
.small {
  font-size: 92%;
}
mark,
.mark {
  background-color: #fcf8e3;
  padding: .2em;
}
.text-left {
  text-align: left;
}
.text-right {
  text-align: right;
}
.text-center {
  text-align: center;
}
.text-justify {
  text-align: justify;
}
.text-nowrap {
  white-space: nowrap;
}
.text-lowercase {
  text-transform: lowercase;
}
.text-uppercase {
  text-transform: uppercase;
}
.text-capitalize {
  text-transform: capitalize;
}
.text-muted {
  color: #777777;
}
.text-primary {
  color: #337ab7;
}
a.text-primary:hover,
a.text-primary:focus {
  color: #286090;
}
.text-success {
  color: #3c763d;
}
a.text-success:hover,
a.text-success:focus {
  color: #2b542c;
}
.text-info {
  color: #31708f;
}
a.text-info:hover,
a.text-info:focus {
  color: #245269;
}
.text-warning {
  color: #8a6d3b;
}
a.text-warning:hover,
a.text-warning:focus {
  color: #66512c;
}
.text-danger {
  color: #a94442;
}
a.text-danger:hover,
a.text-danger:focus {
  color: #843534;
}
.bg-primary {
  color: #fff;
  background-color: #337ab7;
}
a.bg-primary:hover,
a.bg-primary:focus {
  background-color: #286090;
}
.bg-success {
  background-color: #dff0d8;
}
a.bg-success:hover,
a.bg-success:focus {
  background-color: #c1e2b3;
}
.bg-info {
  background-color: #d9edf7;
}
a.bg-info:hover,
a.bg-info:focus {
  background-color: #afd9ee;
}
.bg-warning {
  background-color: #fcf8e3;
}
a.bg-warning:hover,
a.bg-warning:focus {
  background-color: #f7ecb5;
}
.bg-danger {
  background-color: #f2dede;
}
a.bg-danger:hover,
a.bg-danger:focus {
  background-color: #e4b9b9;
}
.page-header {
  padding-bottom: 8px;
  margin: 36px 0 18px;
  border-bottom: 1px solid #eeeeee;
}
ul,
ol {
  margin-top: 0;
  margin-bottom: 9px;
}
ul ul,
ol ul,
ul ol,
ol ol {
  margin-bottom: 0;
}
.list-unstyled {
  padding-left: 0;
  list-style: none;
}
.list-inline {
  padding-left: 0;
  list-style: none;
  margin-left: -5px;
}
.list-inline > li {
  display: inline-block;
  padding-left: 5px;
  padding-right: 5px;
}
dl {
  margin-top: 0;
  margin-bottom: 18px;
}
dt,
dd {
  line-height: 1.42857143;
}
dt {
  font-weight: bold;
}
dd {
  margin-left: 0;
}
@media (min-width: 541px) {
  .dl-horizontal dt {
    float: left;
    width: 160px;
    clear: left;
    text-align: right;
    overflow: hidden;
    text-overflow: ellipsis;
    white-space: nowrap;
  }
  .dl-horizontal dd {
    margin-left: 180px;
  }
}
abbr[title],
abbr[data-original-title] {
  cursor: help;
  border-bottom: 1px dotted #777777;
}
.initialism {
  font-size: 90%;
  text-transform: uppercase;
}
blockquote {
  padding: 9px 18px;
  margin: 0 0 18px;
  font-size: inherit;
  border-left: 5px solid #eeeeee;
}
blockquote p:last-child,
blockquote ul:last-child,
blockquote ol:last-child {
  margin-bottom: 0;
}
blockquote footer,
blockquote small,
blockquote .small {
  display: block;
  font-size: 80%;
  line-height: 1.42857143;
  color: #777777;
}
blockquote footer:before,
blockquote small:before,
blockquote .small:before {
  content: '\2014 \00A0';
}
.blockquote-reverse,
blockquote.pull-right {
  padding-right: 15px;
  padding-left: 0;
  border-right: 5px solid #eeeeee;
  border-left: 0;
  text-align: right;
}
.blockquote-reverse footer:before,
blockquote.pull-right footer:before,
.blockquote-reverse small:before,
blockquote.pull-right small:before,
.blockquote-reverse .small:before,
blockquote.pull-right .small:before {
  content: '';
}
.blockquote-reverse footer:after,
blockquote.pull-right footer:after,
.blockquote-reverse small:after,
blockquote.pull-right small:after,
.blockquote-reverse .small:after,
blockquote.pull-right .small:after {
  content: '\00A0 \2014';
}
address {
  margin-bottom: 18px;
  font-style: normal;
  line-height: 1.42857143;
}
code,
kbd,
pre,
samp {
  font-family: monospace;
}
code {
  padding: 2px 4px;
  font-size: 90%;
  color: #c7254e;
  background-color: #f9f2f4;
  border-radius: 2px;
}
kbd {
  padding: 2px 4px;
  font-size: 90%;
  color: #888;
  background-color: transparent;
  border-radius: 1px;
  box-shadow: inset 0 -1px 0 rgba(0, 0, 0, 0.25);
}
kbd kbd {
  padding: 0;
  font-size: 100%;
  font-weight: bold;
  box-shadow: none;
}
pre {
  display: block;
  padding: 8.5px;
  margin: 0 0 9px;
  font-size: 12px;
  line-height: 1.42857143;
  word-break: break-all;
  word-wrap: break-word;
  color: #333333;
  background-color: #f5f5f5;
  border: 1px solid #ccc;
  border-radius: 2px;
}
pre code {
  padding: 0;
  font-size: inherit;
  color: inherit;
  white-space: pre-wrap;
  background-color: transparent;
  border-radius: 0;
}
.pre-scrollable {
  max-height: 340px;
  overflow-y: scroll;
}
.container {
  margin-right: auto;
  margin-left: auto;
  padding-left: 0px;
  padding-right: 0px;
}
@media (min-width: 768px) {
  .container {
    width: 768px;
  }
}
@media (min-width: 992px) {
  .container {
    width: 940px;
  }
}
@media (min-width: 1200px) {
  .container {
    width: 1140px;
  }
}
.container-fluid {
  margin-right: auto;
  margin-left: auto;
  padding-left: 0px;
  padding-right: 0px;
}
.row {
  margin-left: 0px;
  margin-right: 0px;
}
.col-xs-1, .col-sm-1, .col-md-1, .col-lg-1, .col-xs-2, .col-sm-2, .col-md-2, .col-lg-2, .col-xs-3, .col-sm-3, .col-md-3, .col-lg-3, .col-xs-4, .col-sm-4, .col-md-4, .col-lg-4, .col-xs-5, .col-sm-5, .col-md-5, .col-lg-5, .col-xs-6, .col-sm-6, .col-md-6, .col-lg-6, .col-xs-7, .col-sm-7, .col-md-7, .col-lg-7, .col-xs-8, .col-sm-8, .col-md-8, .col-lg-8, .col-xs-9, .col-sm-9, .col-md-9, .col-lg-9, .col-xs-10, .col-sm-10, .col-md-10, .col-lg-10, .col-xs-11, .col-sm-11, .col-md-11, .col-lg-11, .col-xs-12, .col-sm-12, .col-md-12, .col-lg-12 {
  position: relative;
  min-height: 1px;
  padding-left: 0px;
  padding-right: 0px;
}
.col-xs-1, .col-xs-2, .col-xs-3, .col-xs-4, .col-xs-5, .col-xs-6, .col-xs-7, .col-xs-8, .col-xs-9, .col-xs-10, .col-xs-11, .col-xs-12 {
  float: left;
}
.col-xs-12 {
  width: 100%;
}
.col-xs-11 {
  width: 91.66666667%;
}
.col-xs-10 {
  width: 83.33333333%;
}
.col-xs-9 {
  width: 75%;
}
.col-xs-8 {
  width: 66.66666667%;
}
.col-xs-7 {
  width: 58.33333333%;
}
.col-xs-6 {
  width: 50%;
}
.col-xs-5 {
  width: 41.66666667%;
}
.col-xs-4 {
  width: 33.33333333%;
}
.col-xs-3 {
  width: 25%;
}
.col-xs-2 {
  width: 16.66666667%;
}
.col-xs-1 {
  width: 8.33333333%;
}
.col-xs-pull-12 {
  right: 100%;
}
.col-xs-pull-11 {
  right: 91.66666667%;
}
.col-xs-pull-10 {
  right: 83.33333333%;
}
.col-xs-pull-9 {
  right: 75%;
}
.col-xs-pull-8 {
  right: 66.66666667%;
}
.col-xs-pull-7 {
  right: 58.33333333%;
}
.col-xs-pull-6 {
  right: 50%;
}
.col-xs-pull-5 {
  right: 41.66666667%;
}
.col-xs-pull-4 {
  right: 33.33333333%;
}
.col-xs-pull-3 {
  right: 25%;
}
.col-xs-pull-2 {
  right: 16.66666667%;
}
.col-xs-pull-1 {
  right: 8.33333333%;
}
.col-xs-pull-0 {
  right: auto;
}
.col-xs-push-12 {
  left: 100%;
}
.col-xs-push-11 {
  left: 91.66666667%;
}
.col-xs-push-10 {
  left: 83.33333333%;
}
.col-xs-push-9 {
  left: 75%;
}
.col-xs-push-8 {
  left: 66.66666667%;
}
.col-xs-push-7 {
  left: 58.33333333%;
}
.col-xs-push-6 {
  left: 50%;
}
.col-xs-push-5 {
  left: 41.66666667%;
}
.col-xs-push-4 {
  left: 33.33333333%;
}
.col-xs-push-3 {
  left: 25%;
}
.col-xs-push-2 {
  left: 16.66666667%;
}
.col-xs-push-1 {
  left: 8.33333333%;
}
.col-xs-push-0 {
  left: auto;
}
.col-xs-offset-12 {
  margin-left: 100%;
}
.col-xs-offset-11 {
  margin-left: 91.66666667%;
}
.col-xs-offset-10 {
  margin-left: 83.33333333%;
}
.col-xs-offset-9 {
  margin-left: 75%;
}
.col-xs-offset-8 {
  margin-left: 66.66666667%;
}
.col-xs-offset-7 {
  margin-left: 58.33333333%;
}
.col-xs-offset-6 {
  margin-left: 50%;
}
.col-xs-offset-5 {
  margin-left: 41.66666667%;
}
.col-xs-offset-4 {
  margin-left: 33.33333333%;
}
.col-xs-offset-3 {
  margin-left: 25%;
}
.col-xs-offset-2 {
  margin-left: 16.66666667%;
}
.col-xs-offset-1 {
  margin-left: 8.33333333%;
}
.col-xs-offset-0 {
  margin-left: 0%;
}
@media (min-width: 768px) {
  .col-sm-1, .col-sm-2, .col-sm-3, .col-sm-4, .col-sm-5, .col-sm-6, .col-sm-7, .col-sm-8, .col-sm-9, .col-sm-10, .col-sm-11, .col-sm-12 {
    float: left;
  }
  .col-sm-12 {
    width: 100%;
  }
  .col-sm-11 {
    width: 91.66666667%;
  }
  .col-sm-10 {
    width: 83.33333333%;
  }
  .col-sm-9 {
    width: 75%;
  }
  .col-sm-8 {
    width: 66.66666667%;
  }
  .col-sm-7 {
    width: 58.33333333%;
  }
  .col-sm-6 {
    width: 50%;
  }
  .col-sm-5 {
    width: 41.66666667%;
  }
  .col-sm-4 {
    width: 33.33333333%;
  }
  .col-sm-3 {
    width: 25%;
  }
  .col-sm-2 {
    width: 16.66666667%;
  }
  .col-sm-1 {
    width: 8.33333333%;
  }
  .col-sm-pull-12 {
    right: 100%;
  }
  .col-sm-pull-11 {
    right: 91.66666667%;
  }
  .col-sm-pull-10 {
    right: 83.33333333%;
  }
  .col-sm-pull-9 {
    right: 75%;
  }
  .col-sm-pull-8 {
    right: 66.66666667%;
  }
  .col-sm-pull-7 {
    right: 58.33333333%;
  }
  .col-sm-pull-6 {
    right: 50%;
  }
  .col-sm-pull-5 {
    right: 41.66666667%;
  }
  .col-sm-pull-4 {
    right: 33.33333333%;
  }
  .col-sm-pull-3 {
    right: 25%;
  }
  .col-sm-pull-2 {
    right: 16.66666667%;
  }
  .col-sm-pull-1 {
    right: 8.33333333%;
  }
  .col-sm-pull-0 {
    right: auto;
  }
  .col-sm-push-12 {
    left: 100%;
  }
  .col-sm-push-11 {
    left: 91.66666667%;
  }
  .col-sm-push-10 {
    left: 83.33333333%;
  }
  .col-sm-push-9 {
    left: 75%;
  }
  .col-sm-push-8 {
    left: 66.66666667%;
  }
  .col-sm-push-7 {
    left: 58.33333333%;
  }
  .col-sm-push-6 {
    left: 50%;
  }
  .col-sm-push-5 {
    left: 41.66666667%;
  }
  .col-sm-push-4 {
    left: 33.33333333%;
  }
  .col-sm-push-3 {
    left: 25%;
  }
  .col-sm-push-2 {
    left: 16.66666667%;
  }
  .col-sm-push-1 {
    left: 8.33333333%;
  }
  .col-sm-push-0 {
    left: auto;
  }
  .col-sm-offset-12 {
    margin-left: 100%;
  }
  .col-sm-offset-11 {
    margin-left: 91.66666667%;
  }
  .col-sm-offset-10 {
    margin-left: 83.33333333%;
  }
  .col-sm-offset-9 {
    margin-left: 75%;
  }
  .col-sm-offset-8 {
    margin-left: 66.66666667%;
  }
  .col-sm-offset-7 {
    margin-left: 58.33333333%;
  }
  .col-sm-offset-6 {
    margin-left: 50%;
  }
  .col-sm-offset-5 {
    margin-left: 41.66666667%;
  }
  .col-sm-offset-4 {
    margin-left: 33.33333333%;
  }
  .col-sm-offset-3 {
    margin-left: 25%;
  }
  .col-sm-offset-2 {
    margin-left: 16.66666667%;
  }
  .col-sm-offset-1 {
    margin-left: 8.33333333%;
  }
  .col-sm-offset-0 {
    margin-left: 0%;
  }
}
@media (min-width: 992px) {
  .col-md-1, .col-md-2, .col-md-3, .col-md-4, .col-md-5, .col-md-6, .col-md-7, .col-md-8, .col-md-9, .col-md-10, .col-md-11, .col-md-12 {
    float: left;
  }
  .col-md-12 {
    width: 100%;
  }
  .col-md-11 {
    width: 91.66666667%;
  }
  .col-md-10 {
    width: 83.33333333%;
  }
  .col-md-9 {
    width: 75%;
  }
  .col-md-8 {
    width: 66.66666667%;
  }
  .col-md-7 {
    width: 58.33333333%;
  }
  .col-md-6 {
    width: 50%;
  }
  .col-md-5 {
    width: 41.66666667%;
  }
  .col-md-4 {
    width: 33.33333333%;
  }
  .col-md-3 {
    width: 25%;
  }
  .col-md-2 {
    width: 16.66666667%;
  }
  .col-md-1 {
    width: 8.33333333%;
  }
  .col-md-pull-12 {
    right: 100%;
  }
  .col-md-pull-11 {
    right: 91.66666667%;
  }
  .col-md-pull-10 {
    right: 83.33333333%;
  }
  .col-md-pull-9 {
    right: 75%;
  }
  .col-md-pull-8 {
    right: 66.66666667%;
  }
  .col-md-pull-7 {
    right: 58.33333333%;
  }
  .col-md-pull-6 {
    right: 50%;
  }
  .col-md-pull-5 {
    right: 41.66666667%;
  }
  .col-md-pull-4 {
    right: 33.33333333%;
  }
  .col-md-pull-3 {
    right: 25%;
  }
  .col-md-pull-2 {
    right: 16.66666667%;
  }
  .col-md-pull-1 {
    right: 8.33333333%;
  }
  .col-md-pull-0 {
    right: auto;
  }
  .col-md-push-12 {
    left: 100%;
  }
  .col-md-push-11 {
    left: 91.66666667%;
  }
  .col-md-push-10 {
    left: 83.33333333%;
  }
  .col-md-push-9 {
    left: 75%;
  }
  .col-md-push-8 {
    left: 66.66666667%;
  }
  .col-md-push-7 {
    left: 58.33333333%;
  }
  .col-md-push-6 {
    left: 50%;
  }
  .col-md-push-5 {
    left: 41.66666667%;
  }
  .col-md-push-4 {
    left: 33.33333333%;
  }
  .col-md-push-3 {
    left: 25%;
  }
  .col-md-push-2 {
    left: 16.66666667%;
  }
  .col-md-push-1 {
    left: 8.33333333%;
  }
  .col-md-push-0 {
    left: auto;
  }
  .col-md-offset-12 {
    margin-left: 100%;
  }
  .col-md-offset-11 {
    margin-left: 91.66666667%;
  }
  .col-md-offset-10 {
    margin-left: 83.33333333%;
  }
  .col-md-offset-9 {
    margin-left: 75%;
  }
  .col-md-offset-8 {
    margin-left: 66.66666667%;
  }
  .col-md-offset-7 {
    margin-left: 58.33333333%;
  }
  .col-md-offset-6 {
    margin-left: 50%;
  }
  .col-md-offset-5 {
    margin-left: 41.66666667%;
  }
  .col-md-offset-4 {
    margin-left: 33.33333333%;
  }
  .col-md-offset-3 {
    margin-left: 25%;
  }
  .col-md-offset-2 {
    margin-left: 16.66666667%;
  }
  .col-md-offset-1 {
    margin-left: 8.33333333%;
  }
  .col-md-offset-0 {
    margin-left: 0%;
  }
}
@media (min-width: 1200px) {
  .col-lg-1, .col-lg-2, .col-lg-3, .col-lg-4, .col-lg-5, .col-lg-6, .col-lg-7, .col-lg-8, .col-lg-9, .col-lg-10, .col-lg-11, .col-lg-12 {
    float: left;
  }
  .col-lg-12 {
    width: 100%;
  }
  .col-lg-11 {
    width: 91.66666667%;
  }
  .col-lg-10 {
    width: 83.33333333%;
  }
  .col-lg-9 {
    width: 75%;
  }
  .col-lg-8 {
    width: 66.66666667%;
  }
  .col-lg-7 {
    width: 58.33333333%;
  }
  .col-lg-6 {
    width: 50%;
  }
  .col-lg-5 {
    width: 41.66666667%;
  }
  .col-lg-4 {
    width: 33.33333333%;
  }
  .col-lg-3 {
    width: 25%;
  }
  .col-lg-2 {
    width: 16.66666667%;
  }
  .col-lg-1 {
    width: 8.33333333%;
  }
  .col-lg-pull-12 {
    right: 100%;
  }
  .col-lg-pull-11 {
    right: 91.66666667%;
  }
  .col-lg-pull-10 {
    right: 83.33333333%;
  }
  .col-lg-pull-9 {
    right: 75%;
  }
  .col-lg-pull-8 {
    right: 66.66666667%;
  }
  .col-lg-pull-7 {
    right: 58.33333333%;
  }
  .col-lg-pull-6 {
    right: 50%;
  }
  .col-lg-pull-5 {
    right: 41.66666667%;
  }
  .col-lg-pull-4 {
    right: 33.33333333%;
  }
  .col-lg-pull-3 {
    right: 25%;
  }
  .col-lg-pull-2 {
    right: 16.66666667%;
  }
  .col-lg-pull-1 {
    right: 8.33333333%;
  }
  .col-lg-pull-0 {
    right: auto;
  }
  .col-lg-push-12 {
    left: 100%;
  }
  .col-lg-push-11 {
    left: 91.66666667%;
  }
  .col-lg-push-10 {
    left: 83.33333333%;
  }
  .col-lg-push-9 {
    left: 75%;
  }
  .col-lg-push-8 {
    left: 66.66666667%;
  }
  .col-lg-push-7 {
    left: 58.33333333%;
  }
  .col-lg-push-6 {
    left: 50%;
  }
  .col-lg-push-5 {
    left: 41.66666667%;
  }
  .col-lg-push-4 {
    left: 33.33333333%;
  }
  .col-lg-push-3 {
    left: 25%;
  }
  .col-lg-push-2 {
    left: 16.66666667%;
  }
  .col-lg-push-1 {
    left: 8.33333333%;
  }
  .col-lg-push-0 {
    left: auto;
  }
  .col-lg-offset-12 {
    margin-left: 100%;
  }
  .col-lg-offset-11 {
    margin-left: 91.66666667%;
  }
  .col-lg-offset-10 {
    margin-left: 83.33333333%;
  }
  .col-lg-offset-9 {
    margin-left: 75%;
  }
  .col-lg-offset-8 {
    margin-left: 66.66666667%;
  }
  .col-lg-offset-7 {
    margin-left: 58.33333333%;
  }
  .col-lg-offset-6 {
    margin-left: 50%;
  }
  .col-lg-offset-5 {
    margin-left: 41.66666667%;
  }
  .col-lg-offset-4 {
    margin-left: 33.33333333%;
  }
  .col-lg-offset-3 {
    margin-left: 25%;
  }
  .col-lg-offset-2 {
    margin-left: 16.66666667%;
  }
  .col-lg-offset-1 {
    margin-left: 8.33333333%;
  }
  .col-lg-offset-0 {
    margin-left: 0%;
  }
}
table {
  background-color: transparent;
}
caption {
  padding-top: 8px;
  padding-bottom: 8px;
  color: #777777;
  text-align: left;
}
th {
  text-align: left;
}
.table {
  width: 100%;
  max-width: 100%;
  margin-bottom: 18px;
}
.table > thead > tr > th,
.table > tbody > tr > th,
.table > tfoot > tr > th,
.table > thead > tr > td,
.table > tbody > tr > td,
.table > tfoot > tr > td {
  padding: 8px;
  line-height: 1.42857143;
  vertical-align: top;
  border-top: 1px solid #ddd;
}
.table > thead > tr > th {
  vertical-align: bottom;
  border-bottom: 2px solid #ddd;
}
.table > caption + thead > tr:first-child > th,
.table > colgroup + thead > tr:first-child > th,
.table > thead:first-child > tr:first-child > th,
.table > caption + thead > tr:first-child > td,
.table > colgroup + thead > tr:first-child > td,
.table > thead:first-child > tr:first-child > td {
  border-top: 0;
}
.table > tbody + tbody {
  border-top: 2px solid #ddd;
}
.table .table {
  background-color: #fff;
}
.table-condensed > thead > tr > th,
.table-condensed > tbody > tr > th,
.table-condensed > tfoot > tr > th,
.table-condensed > thead > tr > td,
.table-condensed > tbody > tr > td,
.table-condensed > tfoot > tr > td {
  padding: 5px;
}
.table-bordered {
  border: 1px solid #ddd;
}
.table-bordered > thead > tr > th,
.table-bordered > tbody > tr > th,
.table-bordered > tfoot > tr > th,
.table-bordered > thead > tr > td,
.table-bordered > tbody > tr > td,
.table-bordered > tfoot > tr > td {
  border: 1px solid #ddd;
}
.table-bordered > thead > tr > th,
.table-bordered > thead > tr > td {
  border-bottom-width: 2px;
}
.table-striped > tbody > tr:nth-of-type(odd) {
  background-color: #f9f9f9;
}
.table-hover > tbody > tr:hover {
  background-color: #f5f5f5;
}
table col[class*="col-"] {
  position: static;
  float: none;
  display: table-column;
}
table td[class*="col-"],
table th[class*="col-"] {
  position: static;
  float: none;
  display: table-cell;
}
.table > thead > tr > td.active,
.table > tbody > tr > td.active,
.table > tfoot > tr > td.active,
.table > thead > tr > th.active,
.table > tbody > tr > th.active,
.table > tfoot > tr > th.active,
.table > thead > tr.active > td,
.table > tbody > tr.active > td,
.table > tfoot > tr.active > td,
.table > thead > tr.active > th,
.table > tbody > tr.active > th,
.table > tfoot > tr.active > th {
  background-color: #f5f5f5;
}
.table-hover > tbody > tr > td.active:hover,
.table-hover > tbody > tr > th.active:hover,
.table-hover > tbody > tr.active:hover > td,
.table-hover > tbody > tr:hover > .active,
.table-hover > tbody > tr.active:hover > th {
  background-color: #e8e8e8;
}
.table > thead > tr > td.success,
.table > tbody > tr > td.success,
.table > tfoot > tr > td.success,
.table > thead > tr > th.success,
.table > tbody > tr > th.success,
.table > tfoot > tr > th.success,
.table > thead > tr.success > td,
.table > tbody > tr.success > td,
.table > tfoot > tr.success > td,
.table > thead > tr.success > th,
.table > tbody > tr.success > th,
.table > tfoot > tr.success > th {
  background-color: #dff0d8;
}
.table-hover > tbody > tr > td.success:hover,
.table-hover > tbody > tr > th.success:hover,
.table-hover > tbody > tr.success:hover > td,
.table-hover > tbody > tr:hover > .success,
.table-hover > tbody > tr.success:hover > th {
  background-color: #d0e9c6;
}
.table > thead > tr > td.info,
.table > tbody > tr > td.info,
.table > tfoot > tr > td.info,
.table > thead > tr > th.info,
.table > tbody > tr > th.info,
.table > tfoot > tr > th.info,
.table > thead > tr.info > td,
.table > tbody > tr.info > td,
.table > tfoot > tr.info > td,
.table > thead > tr.info > th,
.table > tbody > tr.info > th,
.table > tfoot > tr.info > th {
  background-color: #d9edf7;
}
.table-hover > tbody > tr > td.info:hover,
.table-hover > tbody > tr > th.info:hover,
.table-hover > tbody > tr.info:hover > td,
.table-hover > tbody > tr:hover > .info,
.table-hover > tbody > tr.info:hover > th {
  background-color: #c4e3f3;
}
.table > thead > tr > td.warning,
.table > tbody > tr > td.warning,
.table > tfoot > tr > td.warning,
.table > thead > tr > th.warning,
.table > tbody > tr > th.warning,
.table > tfoot > tr > th.warning,
.table > thead > tr.warning > td,
.table > tbody > tr.warning > td,
.table > tfoot > tr.warning > td,
.table > thead > tr.warning > th,
.table > tbody > tr.warning > th,
.table > tfoot > tr.warning > th {
  background-color: #fcf8e3;
}
.table-hover > tbody > tr > td.warning:hover,
.table-hover > tbody > tr > th.warning:hover,
.table-hover > tbody > tr.warning:hover > td,
.table-hover > tbody > tr:hover > .warning,
.table-hover > tbody > tr.warning:hover > th {
  background-color: #faf2cc;
}
.table > thead > tr > td.danger,
.table > tbody > tr > td.danger,
.table > tfoot > tr > td.danger,
.table > thead > tr > th.danger,
.table > tbody > tr > th.danger,
.table > tfoot > tr > th.danger,
.table > thead > tr.danger > td,
.table > tbody > tr.danger > td,
.table > tfoot > tr.danger > td,
.table > thead > tr.danger > th,
.table > tbody > tr.danger > th,
.table > tfoot > tr.danger > th {
  background-color: #f2dede;
}
.table-hover > tbody > tr > td.danger:hover,
.table-hover > tbody > tr > th.danger:hover,
.table-hover > tbody > tr.danger:hover > td,
.table-hover > tbody > tr:hover > .danger,
.table-hover > tbody > tr.danger:hover > th {
  background-color: #ebcccc;
}
.table-responsive {
  overflow-x: auto;
  min-height: 0.01%;
}
@media screen and (max-width: 767px) {
  .table-responsive {
    width: 100%;
    margin-bottom: 13.5px;
    overflow-y: hidden;
    -ms-overflow-style: -ms-autohiding-scrollbar;
    border: 1px solid #ddd;
  }
  .table-responsive > .table {
    margin-bottom: 0;
  }
  .table-responsive > .table > thead > tr > th,
  .table-responsive > .table > tbody > tr > th,
  .table-responsive > .table > tfoot > tr > th,
  .table-responsive > .table > thead > tr > td,
  .table-responsive > .table > tbody > tr > td,
  .table-responsive > .table > tfoot > tr > td {
    white-space: nowrap;
  }
  .table-responsive > .table-bordered {
    border: 0;
  }
  .table-responsive > .table-bordered > thead > tr > th:first-child,
  .table-responsive > .table-bordered > tbody > tr > th:first-child,
  .table-responsive > .table-bordered > tfoot > tr > th:first-child,
  .table-responsive > .table-bordered > thead > tr > td:first-child,
  .table-responsive > .table-bordered > tbody > tr > td:first-child,
  .table-responsive > .table-bordered > tfoot > tr > td:first-child {
    border-left: 0;
  }
  .table-responsive > .table-bordered > thead > tr > th:last-child,
  .table-responsive > .table-bordered > tbody > tr > th:last-child,
  .table-responsive > .table-bordered > tfoot > tr > th:last-child,
  .table-responsive > .table-bordered > thead > tr > td:last-child,
  .table-responsive > .table-bordered > tbody > tr > td:last-child,
  .table-responsive > .table-bordered > tfoot > tr > td:last-child {
    border-right: 0;
  }
  .table-responsive > .table-bordered > tbody > tr:last-child > th,
  .table-responsive > .table-bordered > tfoot > tr:last-child > th,
  .table-responsive > .table-bordered > tbody > tr:last-child > td,
  .table-responsive > .table-bordered > tfoot > tr:last-child > td {
    border-bottom: 0;
  }
}
fieldset {
  padding: 0;
  margin: 0;
  border: 0;
  min-width: 0;
}
legend {
  display: block;
  width: 100%;
  padding: 0;
  margin-bottom: 18px;
  font-size: 19.5px;
  line-height: inherit;
  color: #333333;
  border: 0;
  border-bottom: 1px solid #e5e5e5;
}
label {
  display: inline-block;
  max-width: 100%;
  margin-bottom: 5px;
  font-weight: bold;
}
input[type="search"] {
  -webkit-box-sizing: border-box;
  -moz-box-sizing: border-box;
  box-sizing: border-box;
}
input[type="radio"],
input[type="checkbox"] {
  margin: 4px 0 0;
  margin-top: 1px \9;
  line-height: normal;
}
input[type="file"] {
  display: block;
}
input[type="range"] {
  display: block;
  width: 100%;
}
select[multiple],
select[size] {
  height: auto;
}
input[type="file"]:focus,
input[type="radio"]:focus,
input[type="checkbox"]:focus {
  outline: 5px auto -webkit-focus-ring-color;
  outline-offset: -2px;
}
output {
  display: block;
  padding-top: 7px;
  font-size: 13px;
  line-height: 1.42857143;
  color: #555555;
}
.form-control {
  display: block;
  width: 100%;
  height: 32px;
  padding: 6px 12px;
  font-size: 13px;
  line-height: 1.42857143;
  color: #555555;
  background-color: #fff;
  background-image: none;
  border: 1px solid #ccc;
  border-radius: 2px;
  -webkit-box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.075);
  box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.075);
  -webkit-transition: border-color ease-in-out .15s, box-shadow ease-in-out .15s;
  -o-transition: border-color ease-in-out .15s, box-shadow ease-in-out .15s;
  transition: border-color ease-in-out .15s, box-shadow ease-in-out .15s;
}
.form-control:focus {
  border-color: #66afe9;
  outline: 0;
  -webkit-box-shadow: inset 0 1px 1px rgba(0,0,0,.075), 0 0 8px rgba(102, 175, 233, 0.6);
  box-shadow: inset 0 1px 1px rgba(0,0,0,.075), 0 0 8px rgba(102, 175, 233, 0.6);
}
.form-control::-moz-placeholder {
  color: #999;
  opacity: 1;
}
.form-control:-ms-input-placeholder {
  color: #999;
}
.form-control::-webkit-input-placeholder {
  color: #999;
}
.form-control::-ms-expand {
  border: 0;
  background-color: transparent;
}
.form-control[disabled],
.form-control[readonly],
fieldset[disabled] .form-control {
  background-color: #eeeeee;
  opacity: 1;
}
.form-control[disabled],
fieldset[disabled] .form-control {
  cursor: not-allowed;
}
textarea.form-control {
  height: auto;
}
input[type="search"] {
  -webkit-appearance: none;
}
@media screen and (-webkit-min-device-pixel-ratio: 0) {
  input[type="date"].form-control,
  input[type="time"].form-control,
  input[type="datetime-local"].form-control,
  input[type="month"].form-control {
    line-height: 32px;
  }
  input[type="date"].input-sm,
  input[type="time"].input-sm,
  input[type="datetime-local"].input-sm,
  input[type="month"].input-sm,
  .input-group-sm input[type="date"],
  .input-group-sm input[type="time"],
  .input-group-sm input[type="datetime-local"],
  .input-group-sm input[type="month"] {
    line-height: 30px;
  }
  input[type="date"].input-lg,
  input[type="time"].input-lg,
  input[type="datetime-local"].input-lg,
  input[type="month"].input-lg,
  .input-group-lg input[type="date"],
  .input-group-lg input[type="time"],
  .input-group-lg input[type="datetime-local"],
  .input-group-lg input[type="month"] {
    line-height: 45px;
  }
}
.form-group {
  margin-bottom: 15px;
}
.radio,
.checkbox {
  position: relative;
  display: block;
  margin-top: 10px;
  margin-bottom: 10px;
}
.radio label,
.checkbox label {
  min-height: 18px;
  padding-left: 20px;
  margin-bottom: 0;
  font-weight: normal;
  cursor: pointer;
}
.radio input[type="radio"],
.radio-inline input[type="radio"],
.checkbox input[type="checkbox"],
.checkbox-inline input[type="checkbox"] {
  position: absolute;
  margin-left: -20px;
  margin-top: 4px \9;
}
.radio + .radio,
.checkbox + .checkbox {
  margin-top: -5px;
}
.radio-inline,
.checkbox-inline {
  position: relative;
  display: inline-block;
  padding-left: 20px;
  margin-bottom: 0;
  vertical-align: middle;
  font-weight: normal;
  cursor: pointer;
}
.radio-inline + .radio-inline,
.checkbox-inline + .checkbox-inline {
  margin-top: 0;
  margin-left: 10px;
}
input[type="radio"][disabled],
input[type="checkbox"][disabled],
input[type="radio"].disabled,
input[type="checkbox"].disabled,
fieldset[disabled] input[type="radio"],
fieldset[disabled] input[type="checkbox"] {
  cursor: not-allowed;
}
.radio-inline.disabled,
.checkbox-inline.disabled,
fieldset[disabled] .radio-inline,
fieldset[disabled] .checkbox-inline {
  cursor: not-allowed;
}
.radio.disabled label,
.checkbox.disabled label,
fieldset[disabled] .radio label,
fieldset[disabled] .checkbox label {
  cursor: not-allowed;
}
.form-control-static {
  padding-top: 7px;
  padding-bottom: 7px;
  margin-bottom: 0;
  min-height: 31px;
}
.form-control-static.input-lg,
.form-control-static.input-sm {
  padding-left: 0;
  padding-right: 0;
}
.input-sm {
  height: 30px;
  padding: 5px 10px;
  font-size: 12px;
  line-height: 1.5;
  border-radius: 1px;
}
select.input-sm {
  height: 30px;
  line-height: 30px;
}
textarea.input-sm,
select[multiple].input-sm {
  height: auto;
}
.form-group-sm .form-control {
  height: 30px;
  padding: 5px 10px;
  font-size: 12px;
  line-height: 1.5;
  border-radius: 1px;
}
.form-group-sm select.form-control {
  height: 30px;
  line-height: 30px;
}
.form-group-sm textarea.form-control,
.form-group-sm select[multiple].form-control {
  height: auto;
}
.form-group-sm .form-control-static {
  height: 30px;
  min-height: 30px;
  padding: 6px 10px;
  font-size: 12px;
  line-height: 1.5;
}
.input-lg {
  height: 45px;
  padding: 10px 16px;
  font-size: 17px;
  line-height: 1.3333333;
  border-radius: 3px;
}
select.input-lg {
  height: 45px;
  line-height: 45px;
}
textarea.input-lg,
select[multiple].input-lg {
  height: auto;
}
.form-group-lg .form-control {
  height: 45px;
  padding: 10px 16px;
  font-size: 17px;
  line-height: 1.3333333;
  border-radius: 3px;
}
.form-group-lg select.form-control {
  height: 45px;
  line-height: 45px;
}
.form-group-lg textarea.form-control,
.form-group-lg select[multiple].form-control {
  height: auto;
}
.form-group-lg .form-control-static {
  height: 45px;
  min-height: 35px;
  padding: 11px 16px;
  font-size: 17px;
  line-height: 1.3333333;
}
.has-feedback {
  position: relative;
}
.has-feedback .form-control {
  padding-right: 40px;
}
.form-control-feedback {
  position: absolute;
  top: 0;
  right: 0;
  z-index: 2;
  display: block;
  width: 32px;
  height: 32px;
  line-height: 32px;
  text-align: center;
  pointer-events: none;
}
.input-lg + .form-control-feedback,
.input-group-lg + .form-control-feedback,
.form-group-lg .form-control + .form-control-feedback {
  width: 45px;
  height: 45px;
  line-height: 45px;
}
.input-sm + .form-control-feedback,
.input-group-sm + .form-control-feedback,
.form-group-sm .form-control + .form-control-feedback {
  width: 30px;
  height: 30px;
  line-height: 30px;
}
.has-success .help-block,
.has-success .control-label,
.has-success .radio,
.has-success .checkbox,
.has-success .radio-inline,
.has-success .checkbox-inline,
.has-success.radio label,
.has-success.checkbox label,
.has-success.radio-inline label,
.has-success.checkbox-inline label {
  color: #3c763d;
}
.has-success .form-control {
  border-color: #3c763d;
  -webkit-box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.075);
  box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.075);
}
.has-success .form-control:focus {
  border-color: #2b542c;
  -webkit-box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.075), 0 0 6px #67b168;
  box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.075), 0 0 6px #67b168;
}
.has-success .input-group-addon {
  color: #3c763d;
  border-color: #3c763d;
  background-color: #dff0d8;
}
.has-success .form-control-feedback {
  color: #3c763d;
}
.has-warning .help-block,
.has-warning .control-label,
.has-warning .radio,
.has-warning .checkbox,
.has-warning .radio-inline,
.has-warning .checkbox-inline,
.has-warning.radio label,
.has-warning.checkbox label,
.has-warning.radio-inline label,
.has-warning.checkbox-inline label {
  color: #8a6d3b;
}
.has-warning .form-control {
  border-color: #8a6d3b;
  -webkit-box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.075);
  box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.075);
}
.has-warning .form-control:focus {
  border-color: #66512c;
  -webkit-box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.075), 0 0 6px #c0a16b;
  box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.075), 0 0 6px #c0a16b;
}
.has-warning .input-group-addon {
  color: #8a6d3b;
  border-color: #8a6d3b;
  background-color: #fcf8e3;
}
.has-warning .form-control-feedback {
  color: #8a6d3b;
}
.has-error .help-block,
.has-error .control-label,
.has-error .radio,
.has-error .checkbox,
.has-error .radio-inline,
.has-error .checkbox-inline,
.has-error.radio label,
.has-error.checkbox label,
.has-error.radio-inline label,
.has-error.checkbox-inline label {
  color: #a94442;
}
.has-error .form-control {
  border-color: #a94442;
  -webkit-box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.075);
  box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.075);
}
.has-error .form-control:focus {
  border-color: #843534;
  -webkit-box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.075), 0 0 6px #ce8483;
  box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.075), 0 0 6px #ce8483;
}
.has-error .input-group-addon {
  color: #a94442;
  border-color: #a94442;
  background-color: #f2dede;
}
.has-error .form-control-feedback {
  color: #a94442;
}
.has-feedback label ~ .form-control-feedback {
  top: 23px;
}
.has-feedback label.sr-only ~ .form-control-feedback {
  top: 0;
}
.help-block {
  display: block;
  margin-top: 5px;
  margin-bottom: 10px;
  color: #404040;
}
@media (min-width: 768px) {
  .form-inline .form-group {
    display: inline-block;
    margin-bottom: 0;
    vertical-align: middle;
  }
  .form-inline .form-control {
    display: inline-block;
    width: auto;
    vertical-align: middle;
  }
  .form-inline .form-control-static {
    display: inline-block;
  }
  .form-inline .input-group {
    display: inline-table;
    vertical-align: middle;
  }
  .form-inline .input-group .input-group-addon,
  .form-inline .input-group .input-group-btn,
  .form-inline .input-group .form-control {
    width: auto;
  }
  .form-inline .input-group > .form-control {
    width: 100%;
  }
  .form-inline .control-label {
    margin-bottom: 0;
    vertical-align: middle;
  }
  .form-inline .radio,
  .form-inline .checkbox {
    display: inline-block;
    margin-top: 0;
    margin-bottom: 0;
    vertical-align: middle;
  }
  .form-inline .radio label,
  .form-inline .checkbox label {
    padding-left: 0;
  }
  .form-inline .radio input[type="radio"],
  .form-inline .checkbox input[type="checkbox"] {
    position: relative;
    margin-left: 0;
  }
  .form-inline .has-feedback .form-control-feedback {
    top: 0;
  }
}
.form-horizontal .radio,
.form-horizontal .checkbox,
.form-horizontal .radio-inline,
.form-horizontal .checkbox-inline {
  margin-top: 0;
  margin-bottom: 0;
  padding-top: 7px;
}
.form-horizontal .radio,
.form-horizontal .checkbox {
  min-height: 25px;
}
.form-horizontal .form-group {
  margin-left: 0px;
  margin-right: 0px;
}
@media (min-width: 768px) {
  .form-horizontal .control-label {
    text-align: right;
    margin-bottom: 0;
    padding-top: 7px;
  }
}
.form-horizontal .has-feedback .form-control-feedback {
  right: 0px;
}
@media (min-width: 768px) {
  .form-horizontal .form-group-lg .control-label {
    padding-top: 11px;
    font-size: 17px;
  }
}
@media (min-width: 768px) {
  .form-horizontal .form-group-sm .control-label {
    padding-top: 6px;
    font-size: 12px;
  }
}
.btn {
  display: inline-block;
  margin-bottom: 0;
  font-weight: normal;
  text-align: center;
  vertical-align: middle;
  touch-action: manipulation;
  cursor: pointer;
  background-image: none;
  border: 1px solid transparent;
  white-space: nowrap;
  padding: 6px 12px;
  font-size: 13px;
  line-height: 1.42857143;
  border-radius: 2px;
  -webkit-user-select: none;
  -moz-user-select: none;
  -ms-user-select: none;
  user-select: none;
}
.btn:focus,
.btn:active:focus,
.btn.active:focus,
.btn.focus,
.btn:active.focus,
.btn.active.focus {
  outline: 5px auto -webkit-focus-ring-color;
  outline-offset: -2px;
}
.btn:hover,
.btn:focus,
.btn.focus {
  color: #333;
  text-decoration: none;
}
.btn:active,
.btn.active {
  outline: 0;
  background-image: none;
  -webkit-box-shadow: inset 0 3px 5px rgba(0, 0, 0, 0.125);
  box-shadow: inset 0 3px 5px rgba(0, 0, 0, 0.125);
}
.btn.disabled,
.btn[disabled],
fieldset[disabled] .btn {
  cursor: not-allowed;
  opacity: 0.65;
  filter: alpha(opacity=65);
  -webkit-box-shadow: none;
  box-shadow: none;
}
a.btn.disabled,
fieldset[disabled] a.btn {
  pointer-events: none;
}
.btn-default {
  color: #333;
  background-color: #fff;
  border-color: #ccc;
}
.btn-default:focus,
.btn-default.focus {
  color: #333;
  background-color: #e6e6e6;
  border-color: #8c8c8c;
}
.btn-default:hover {
  color: #333;
  background-color: #e6e6e6;
  border-color: #adadad;
}
.btn-default:active,
.btn-default.active,
.open > .dropdown-toggle.btn-default {
  color: #333;
  background-color: #e6e6e6;
  border-color: #adadad;
}
.btn-default:active:hover,
.btn-default.active:hover,
.open > .dropdown-toggle.btn-default:hover,
.btn-default:active:focus,
.btn-default.active:focus,
.open > .dropdown-toggle.btn-default:focus,
.btn-default:active.focus,
.btn-default.active.focus,
.open > .dropdown-toggle.btn-default.focus {
  color: #333;
  background-color: #d4d4d4;
  border-color: #8c8c8c;
}
.btn-default:active,
.btn-default.active,
.open > .dropdown-toggle.btn-default {
  background-image: none;
}
.btn-default.disabled:hover,
.btn-default[disabled]:hover,
fieldset[disabled] .btn-default:hover,
.btn-default.disabled:focus,
.btn-default[disabled]:focus,
fieldset[disabled] .btn-default:focus,
.btn-default.disabled.focus,
.btn-default[disabled].focus,
fieldset[disabled] .btn-default.focus {
  background-color: #fff;
  border-color: #ccc;
}
.btn-default .badge {
  color: #fff;
  background-color: #333;
}
.btn-primary {
  color: #fff;
  background-color: #337ab7;
  border-color: #2e6da4;
}
.btn-primary:focus,
.btn-primary.focus {
  color: #fff;
  background-color: #286090;
  border-color: #122b40;
}
.btn-primary:hover {
  color: #fff;
  background-color: #286090;
  border-color: #204d74;
}
.btn-primary:active,
.btn-primary.active,
.open > .dropdown-toggle.btn-primary {
  color: #fff;
  background-color: #286090;
  border-color: #204d74;
}
.btn-primary:active:hover,
.btn-primary.active:hover,
.open > .dropdown-toggle.btn-primary:hover,
.btn-primary:active:focus,
.btn-primary.active:focus,
.open > .dropdown-toggle.btn-primary:focus,
.btn-primary:active.focus,
.btn-primary.active.focus,
.open > .dropdown-toggle.btn-primary.focus {
  color: #fff;
  background-color: #204d74;
  border-color: #122b40;
}
.btn-primary:active,
.btn-primary.active,
.open > .dropdown-toggle.btn-primary {
  background-image: none;
}
.btn-primary.disabled:hover,
.btn-primary[disabled]:hover,
fieldset[disabled] .btn-primary:hover,
.btn-primary.disabled:focus,
.btn-primary[disabled]:focus,
fieldset[disabled] .btn-primary:focus,
.btn-primary.disabled.focus,
.btn-primary[disabled].focus,
fieldset[disabled] .btn-primary.focus {
  background-color: #337ab7;
  border-color: #2e6da4;
}
.btn-primary .badge {
  color: #337ab7;
  background-color: #fff;
}
.btn-success {
  color: #fff;
  background-color: #5cb85c;
  border-color: #4cae4c;
}
.btn-success:focus,
.btn-success.focus {
  color: #fff;
  background-color: #449d44;
  border-color: #255625;
}
.btn-success:hover {
  color: #fff;
  background-color: #449d44;
  border-color: #398439;
}
.btn-success:active,
.btn-success.active,
.open > .dropdown-toggle.btn-success {
  color: #fff;
  background-color: #449d44;
  border-color: #398439;
}
.btn-success:active:hover,
.btn-success.active:hover,
.open > .dropdown-toggle.btn-success:hover,
.btn-success:active:focus,
.btn-success.active:focus,
.open > .dropdown-toggle.btn-success:focus,
.btn-success:active.focus,
.btn-success.active.focus,
.open > .dropdown-toggle.btn-success.focus {
  color: #fff;
  background-color: #398439;
  border-color: #255625;
}
.btn-success:active,
.btn-success.active,
.open > .dropdown-toggle.btn-success {
  background-image: none;
}
.btn-success.disabled:hover,
.btn-success[disabled]:hover,
fieldset[disabled] .btn-success:hover,
.btn-success.disabled:focus,
.btn-success[disabled]:focus,
fieldset[disabled] .btn-success:focus,
.btn-success.disabled.focus,
.btn-success[disabled].focus,
fieldset[disabled] .btn-success.focus {
  background-color: #5cb85c;
  border-color: #4cae4c;
}
.btn-success .badge {
  color: #5cb85c;
  background-color: #fff;
}
.btn-info {
  color: #fff;
  background-color: #5bc0de;
  border-color: #46b8da;
}
.btn-info:focus,
.btn-info.focus {
  color: #fff;
  background-color: #31b0d5;
  border-color: #1b6d85;
}
.btn-info:hover {
  color: #fff;
  background-color: #31b0d5;
  border-color: #269abc;
}
.btn-info:active,
.btn-info.active,
.open > .dropdown-toggle.btn-info {
  color: #fff;
  background-color: #31b0d5;
  border-color: #269abc;
}
.btn-info:active:hover,
.btn-info.active:hover,
.open > .dropdown-toggle.btn-info:hover,
.btn-info:active:focus,
.btn-info.active:focus,
.open > .dropdown-toggle.btn-info:focus,
.btn-info:active.focus,
.btn-info.active.focus,
.open > .dropdown-toggle.btn-info.focus {
  color: #fff;
  background-color: #269abc;
  border-color: #1b6d85;
}
.btn-info:active,
.btn-info.active,
.open > .dropdown-toggle.btn-info {
  background-image: none;
}
.btn-info.disabled:hover,
.btn-info[disabled]:hover,
fieldset[disabled] .btn-info:hover,
.btn-info.disabled:focus,
.btn-info[disabled]:focus,
fieldset[disabled] .btn-info:focus,
.btn-info.disabled.focus,
.btn-info[disabled].focus,
fieldset[disabled] .btn-info.focus {
  background-color: #5bc0de;
  border-color: #46b8da;
}
.btn-info .badge {
  color: #5bc0de;
  background-color: #fff;
}
.btn-warning {
  color: #fff;
  background-color: #f0ad4e;
  border-color: #eea236;
}
.btn-warning:focus,
.btn-warning.focus {
  color: #fff;
  background-color: #ec971f;
  border-color: #985f0d;
}
.btn-warning:hover {
  color: #fff;
  background-color: #ec971f;
  border-color: #d58512;
}
.btn-warning:active,
.btn-warning.active,
.open > .dropdown-toggle.btn-warning {
  color: #fff;
  background-color: #ec971f;
  border-color: #d58512;
}
.btn-warning:active:hover,
.btn-warning.active:hover,
.open > .dropdown-toggle.btn-warning:hover,
.btn-warning:active:focus,
.btn-warning.active:focus,
.open > .dropdown-toggle.btn-warning:focus,
.btn-warning:active.focus,
.btn-warning.active.focus,
.open > .dropdown-toggle.btn-warning.focus {
  color: #fff;
  background-color: #d58512;
  border-color: #985f0d;
}
.btn-warning:active,
.btn-warning.active,
.open > .dropdown-toggle.btn-warning {
  background-image: none;
}
.btn-warning.disabled:hover,
.btn-warning[disabled]:hover,
fieldset[disabled] .btn-warning:hover,
.btn-warning.disabled:focus,
.btn-warning[disabled]:focus,
fieldset[disabled] .btn-warning:focus,
.btn-warning.disabled.focus,
.btn-warning[disabled].focus,
fieldset[disabled] .btn-warning.focus {
  background-color: #f0ad4e;
  border-color: #eea236;
}
.btn-warning .badge {
  color: #f0ad4e;
  background-color: #fff;
}
.btn-danger {
  color: #fff;
  background-color: #d9534f;
  border-color: #d43f3a;
}
.btn-danger:focus,
.btn-danger.focus {
  color: #fff;
  background-color: #c9302c;
  border-color: #761c19;
}
.btn-danger:hover {
  color: #fff;
  background-color: #c9302c;
  border-color: #ac2925;
}
.btn-danger:active,
.btn-danger.active,
.open > .dropdown-toggle.btn-danger {
  color: #fff;
  background-color: #c9302c;
  border-color: #ac2925;
}
.btn-danger:active:hover,
.btn-danger.active:hover,
.open > .dropdown-toggle.btn-danger:hover,
.btn-danger:active:focus,
.btn-danger.active:focus,
.open > .dropdown-toggle.btn-danger:focus,
.btn-danger:active.focus,
.btn-danger.active.focus,
.open > .dropdown-toggle.btn-danger.focus {
  color: #fff;
  background-color: #ac2925;
  border-color: #761c19;
}
.btn-danger:active,
.btn-danger.active,
.open > .dropdown-toggle.btn-danger {
  background-image: none;
}
.btn-danger.disabled:hover,
.btn-danger[disabled]:hover,
fieldset[disabled] .btn-danger:hover,
.btn-danger.disabled:focus,
.btn-danger[disabled]:focus,
fieldset[disabled] .btn-danger:focus,
.btn-danger.disabled.focus,
.btn-danger[disabled].focus,
fieldset[disabled] .btn-danger.focus {
  background-color: #d9534f;
  border-color: #d43f3a;
}
.btn-danger .badge {
  color: #d9534f;
  background-color: #fff;
}
.btn-link {
  color: #337ab7;
  font-weight: normal;
  border-radius: 0;
}
.btn-link,
.btn-link:active,
.btn-link.active,
.btn-link[disabled],
fieldset[disabled] .btn-link {
  background-color: transparent;
  -webkit-box-shadow: none;
  box-shadow: none;
}
.btn-link,
.btn-link:hover,
.btn-link:focus,
.btn-link:active {
  border-color: transparent;
}
.btn-link:hover,
.btn-link:focus {
  color: #23527c;
  text-decoration: underline;
  background-color: transparent;
}
.btn-link[disabled]:hover,
fieldset[disabled] .btn-link:hover,
.btn-link[disabled]:focus,
fieldset[disabled] .btn-link:focus {
  color: #777777;
  text-decoration: none;
}
.btn-lg,
.btn-group-lg > .btn {
  padding: 10px 16px;
  font-size: 17px;
  line-height: 1.3333333;
  border-radius: 3px;
}
.btn-sm,
.btn-group-sm > .btn {
  padding: 5px 10px;
  font-size: 12px;
  line-height: 1.5;
  border-radius: 1px;
}
.btn-xs,
.btn-group-xs > .btn {
  padding: 1px 5px;
  font-size: 12px;
  line-height: 1.5;
  border-radius: 1px;
}
.btn-block {
  display: block;
  width: 100%;
}
.btn-block + .btn-block {
  margin-top: 5px;
}
input[type="submit"].btn-block,
input[type="reset"].btn-block,
input[type="button"].btn-block {
  width: 100%;
}
.fade {
  opacity: 0;
  -webkit-transition: opacity 0.15s linear;
  -o-transition: opacity 0.15s linear;
  transition: opacity 0.15s linear;
}
.fade.in {
  opacity: 1;
}
.collapse {
  display: none;
}
.collapse.in {
  display: block;
}
tr.collapse.in {
  display: table-row;
}
tbody.collapse.in {
  display: table-row-group;
}
.collapsing {
  position: relative;
  height: 0;
  overflow: hidden;
  -webkit-transition-property: height, visibility;
  transition-property: height, visibility;
  -webkit-transition-duration: 0.35s;
  transition-duration: 0.35s;
  -webkit-transition-timing-function: ease;
  transition-timing-function: ease;
}
.caret {
  display: inline-block;
  width: 0;
  height: 0;
  margin-left: 2px;
  vertical-align: middle;
  border-top: 4px dashed;
  border-top: 4px solid \9;
  border-right: 4px solid transparent;
  border-left: 4px solid transparent;
}
.dropup,
.dropdown {
  position: relative;
}
.dropdown-toggle:focus {
  outline: 0;
}
.dropdown-menu {
  position: absolute;
  top: 100%;
  left: 0;
  z-index: 1000;
  display: none;
  float: left;
  min-width: 160px;
  padding: 5px 0;
  margin: 2px 0 0;
  list-style: none;
  font-size: 13px;
  text-align: left;
  background-color: #fff;
  border: 1px solid #ccc;
  border: 1px solid rgba(0, 0, 0, 0.15);
  border-radius: 2px;
  -webkit-box-shadow: 0 6px 12px rgba(0, 0, 0, 0.175);
  box-shadow: 0 6px 12px rgba(0, 0, 0, 0.175);
  background-clip: padding-box;
}
.dropdown-menu.pull-right {
  right: 0;
  left: auto;
}
.dropdown-menu .divider {
  height: 1px;
  margin: 8px 0;
  overflow: hidden;
  background-color: #e5e5e5;
}
.dropdown-menu > li > a {
  display: block;
  padding: 3px 20px;
  clear: both;
  font-weight: normal;
  line-height: 1.42857143;
  color: #333333;
  white-space: nowrap;
}
.dropdown-menu > li > a:hover,
.dropdown-menu > li > a:focus {
  text-decoration: none;
  color: #262626;
  background-color: #f5f5f5;
}
.dropdown-menu > .active > a,
.dropdown-menu > .active > a:hover,
.dropdown-menu > .active > a:focus {
  color: #fff;
  text-decoration: none;
  outline: 0;
  background-color: #337ab7;
}
.dropdown-menu > .disabled > a,
.dropdown-menu > .disabled > a:hover,
.dropdown-menu > .disabled > a:focus {
  color: #777777;
}
.dropdown-menu > .disabled > a:hover,
.dropdown-menu > .disabled > a:focus {
  text-decoration: none;
  background-color: transparent;
  background-image: none;
  filter: progid:DXImageTransform.Microsoft.gradient(enabled = false);
  cursor: not-allowed;
}
.open > .dropdown-menu {
  display: block;
}
.open > a {
  outline: 0;
}
.dropdown-menu-right {
  left: auto;
  right: 0;
}
.dropdown-menu-left {
  left: 0;
  right: auto;
}
.dropdown-header {
  display: block;
  padding: 3px 20px;
  font-size: 12px;
  line-height: 1.42857143;
  color: #777777;
  white-space: nowrap;
}
.dropdown-backdrop {
  position: fixed;
  left: 0;
  right: 0;
  bottom: 0;
  top: 0;
  z-index: 990;
}
.pull-right > .dropdown-menu {
  right: 0;
  left: auto;
}
.dropup .caret,
.navbar-fixed-bottom .dropdown .caret {
  border-top: 0;
  border-bottom: 4px dashed;
  border-bottom: 4px solid \9;
  content: "";
}
.dropup .dropdown-menu,
.navbar-fixed-bottom .dropdown .dropdown-menu {
  top: auto;
  bottom: 100%;
  margin-bottom: 2px;
}
@media (min-width: 541px) {
  .navbar-right .dropdown-menu {
    left: auto;
    right: 0;
  }
  .navbar-right .dropdown-menu-left {
    left: 0;
    right: auto;
  }
}
.btn-group,
.btn-group-vertical {
  position: relative;
  display: inline-block;
  vertical-align: middle;
}
.btn-group > .btn,
.btn-group-vertical > .btn {
  position: relative;
  float: left;
}
.btn-group > .btn:hover,
.btn-group-vertical > .btn:hover,
.btn-group > .btn:focus,
.btn-group-vertical > .btn:focus,
.btn-group > .btn:active,
.btn-group-vertical > .btn:active,
.btn-group > .btn.active,
.btn-group-vertical > .btn.active {
  z-index: 2;
}
.btn-group .btn + .btn,
.btn-group .btn + .btn-group,
.btn-group .btn-group + .btn,
.btn-group .btn-group + .btn-group {
  margin-left: -1px;
}
.btn-toolbar {
  margin-left: -5px;
}
.btn-toolbar .btn,
.btn-toolbar .btn-group,
.btn-toolbar .input-group {
  float: left;
}
.btn-toolbar > .btn,
.btn-toolbar > .btn-group,
.btn-toolbar > .input-group {
  margin-left: 5px;
}
.btn-group > .btn:not(:first-child):not(:last-child):not(.dropdown-toggle) {
  border-radius: 0;
}
.btn-group > .btn:first-child {
  margin-left: 0;
}
.btn-group > .btn:first-child:not(:last-child):not(.dropdown-toggle) {
  border-bottom-right-radius: 0;
  border-top-right-radius: 0;
}
.btn-group > .btn:last-child:not(:first-child),
.btn-group > .dropdown-toggle:not(:first-child) {
  border-bottom-left-radius: 0;
  border-top-left-radius: 0;
}
.btn-group > .btn-group {
  float: left;
}
.btn-group > .btn-group:not(:first-child):not(:last-child) > .btn {
  border-radius: 0;
}
.btn-group > .btn-group:first-child:not(:last-child) > .btn:last-child,
.btn-group > .btn-group:first-child:not(:last-child) > .dropdown-toggle {
  border-bottom-right-radius: 0;
  border-top-right-radius: 0;
}
.btn-group > .btn-group:last-child:not(:first-child) > .btn:first-child {
  border-bottom-left-radius: 0;
  border-top-left-radius: 0;
}
.btn-group .dropdown-toggle:active,
.btn-group.open .dropdown-toggle {
  outline: 0;
}
.btn-group > .btn + .dropdown-toggle {
  padding-left: 8px;
  padding-right: 8px;
}
.btn-group > .btn-lg + .dropdown-toggle {
  padding-left: 12px;
  padding-right: 12px;
}
.btn-group.open .dropdown-toggle {
  -webkit-box-shadow: inset 0 3px 5px rgba(0, 0, 0, 0.125);
  box-shadow: inset 0 3px 5px rgba(0, 0, 0, 0.125);
}
.btn-group.open .dropdown-toggle.btn-link {
  -webkit-box-shadow: none;
  box-shadow: none;
}
.btn .caret {
  margin-left: 0;
}
.btn-lg .caret {
  border-width: 5px 5px 0;
  border-bottom-width: 0;
}
.dropup .btn-lg .caret {
  border-width: 0 5px 5px;
}
.btn-group-vertical > .btn,
.btn-group-vertical > .btn-group,
.btn-group-vertical > .btn-group > .btn {
  display: block;
  float: none;
  width: 100%;
  max-width: 100%;
}
.btn-group-vertical > .btn-group > .btn {
  float: none;
}
.btn-group-vertical > .btn + .btn,
.btn-group-vertical > .btn + .btn-group,
.btn-group-vertical > .btn-group + .btn,
.btn-group-vertical > .btn-group + .btn-group {
  margin-top: -1px;
  margin-left: 0;
}
.btn-group-vertical > .btn:not(:first-child):not(:last-child) {
  border-radius: 0;
}
.btn-group-vertical > .btn:first-child:not(:last-child) {
  border-top-right-radius: 2px;
  border-top-left-radius: 2px;
  border-bottom-right-radius: 0;
  border-bottom-left-radius: 0;
}
.btn-group-vertical > .btn:last-child:not(:first-child) {
  border-top-right-radius: 0;
  border-top-left-radius: 0;
  border-bottom-right-radius: 2px;
  border-bottom-left-radius: 2px;
}
.btn-group-vertical > .btn-group:not(:first-child):not(:last-child) > .btn {
  border-radius: 0;
}
.btn-group-vertical > .btn-group:first-child:not(:last-child) > .btn:last-child,
.btn-group-vertical > .btn-group:first-child:not(:last-child) > .dropdown-toggle {
  border-bottom-right-radius: 0;
  border-bottom-left-radius: 0;
}
.btn-group-vertical > .btn-group:last-child:not(:first-child) > .btn:first-child {
  border-top-right-radius: 0;
  border-top-left-radius: 0;
}
.btn-group-justified {
  display: table;
  width: 100%;
  table-layout: fixed;
  border-collapse: separate;
}
.btn-group-justified > .btn,
.btn-group-justified > .btn-group {
  float: none;
  display: table-cell;
  width: 1%;
}
.btn-group-justified > .btn-group .btn {
  width: 100%;
}
.btn-group-justified > .btn-group .dropdown-menu {
  left: auto;
}
[data-toggle="buttons"] > .btn input[type="radio"],
[data-toggle="buttons"] > .btn-group > .btn input[type="radio"],
[data-toggle="buttons"] > .btn input[type="checkbox"],
[data-toggle="buttons"] > .btn-group > .btn input[type="checkbox"] {
  position: absolute;
  clip: rect(0, 0, 0, 0);
  pointer-events: none;
}
.input-group {
  position: relative;
  display: table;
  border-collapse: separate;
}
.input-group[class*="col-"] {
  float: none;
  padding-left: 0;
  padding-right: 0;
}
.input-group .form-control {
  position: relative;
  z-index: 2;
  float: left;
  width: 100%;
  margin-bottom: 0;
}
.input-group .form-control:focus {
  z-index: 3;
}
.input-group-lg > .form-control,
.input-group-lg > .input-group-addon,
.input-group-lg > .input-group-btn > .btn {
  height: 45px;
  padding: 10px 16px;
  font-size: 17px;
  line-height: 1.3333333;
  border-radius: 3px;
}
select.input-group-lg > .form-control,
select.input-group-lg > .input-group-addon,
select.input-group-lg > .input-group-btn > .btn {
  height: 45px;
  line-height: 45px;
}
textarea.input-group-lg > .form-control,
textarea.input-group-lg > .input-group-addon,
textarea.input-group-lg > .input-group-btn > .btn,
select[multiple].input-group-lg > .form-control,
select[multiple].input-group-lg > .input-group-addon,
select[multiple].input-group-lg > .input-group-btn > .btn {
  height: auto;
}
.input-group-sm > .form-control,
.input-group-sm > .input-group-addon,
.input-group-sm > .input-group-btn > .btn {
  height: 30px;
  padding: 5px 10px;
  font-size: 12px;
  line-height: 1.5;
  border-radius: 1px;
}
select.input-group-sm > .form-control,
select.input-group-sm > .input-group-addon,
select.input-group-sm > .input-group-btn > .btn {
  height: 30px;
  line-height: 30px;
}
textarea.input-group-sm > .form-control,
textarea.input-group-sm > .input-group-addon,
textarea.input-group-sm > .input-group-btn > .btn,
select[multiple].input-group-sm > .form-control,
select[multiple].input-group-sm > .input-group-addon,
select[multiple].input-group-sm > .input-group-btn > .btn {
  height: auto;
}
.input-group-addon,
.input-group-btn,
.input-group .form-control {
  display: table-cell;
}
.input-group-addon:not(:first-child):not(:last-child),
.input-group-btn:not(:first-child):not(:last-child),
.input-group .form-control:not(:first-child):not(:last-child) {
  border-radius: 0;
}
.input-group-addon,
.input-group-btn {
  width: 1%;
  white-space: nowrap;
  vertical-align: middle;
}
.input-group-addon {
  padding: 6px 12px;
  font-size: 13px;
  font-weight: normal;
  line-height: 1;
  color: #555555;
  text-align: center;
  background-color: #eeeeee;
  border: 1px solid #ccc;
  border-radius: 2px;
}
.input-group-addon.input-sm {
  padding: 5px 10px;
  font-size: 12px;
  border-radius: 1px;
}
.input-group-addon.input-lg {
  padding: 10px 16px;
  font-size: 17px;
  border-radius: 3px;
}
.input-group-addon input[type="radio"],
.input-group-addon input[type="checkbox"] {
  margin-top: 0;
}
.input-group .form-control:first-child,
.input-group-addon:first-child,
.input-group-btn:first-child > .btn,
.input-group-btn:first-child > .btn-group > .btn,
.input-group-btn:first-child > .dropdown-toggle,
.input-group-btn:last-child > .btn:not(:last-child):not(.dropdown-toggle),
.input-group-btn:last-child > .btn-group:not(:last-child) > .btn {
  border-bottom-right-radius: 0;
  border-top-right-radius: 0;
}
.input-group-addon:first-child {
  border-right: 0;
}
.input-group .form-control:last-child,
.input-group-addon:last-child,
.input-group-btn:last-child > .btn,
.input-group-btn:last-child > .btn-group > .btn,
.input-group-btn:last-child > .dropdown-toggle,
.input-group-btn:first-child > .btn:not(:first-child),
.input-group-btn:first-child > .btn-group:not(:first-child) > .btn {
  border-bottom-left-radius: 0;
  border-top-left-radius: 0;
}
.input-group-addon:last-child {
  border-left: 0;
}
.input-group-btn {
  position: relative;
  font-size: 0;
  white-space: nowrap;
}
.input-group-btn > .btn {
  position: relative;
}
.input-group-btn > .btn + .btn {
  margin-left: -1px;
}
.input-group-btn > .btn:hover,
.input-group-btn > .btn:focus,
.input-group-btn > .btn:active {
  z-index: 2;
}
.input-group-btn:first-child > .btn,
.input-group-btn:first-child > .btn-group {
  margin-right: -1px;
}
.input-group-btn:last-child > .btn,
.input-group-btn:last-child > .btn-group {
  z-index: 2;
  margin-left: -1px;
}
.nav {
  margin-bottom: 0;
  padding-left: 0;
  list-style: none;
}
.nav > li {
  position: relative;
  display: block;
}
.nav > li > a {
  position: relative;
  display: block;
  padding: 10px 15px;
}
.nav > li > a:hover,
.nav > li > a:focus {
  text-decoration: none;
  background-color: #eeeeee;
}
.nav > li.disabled > a {
  color: #777777;
}
.nav > li.disabled > a:hover,
.nav > li.disabled > a:focus {
  color: #777777;
  text-decoration: none;
  background-color: transparent;
  cursor: not-allowed;
}
.nav .open > a,
.nav .open > a:hover,
.nav .open > a:focus {
  background-color: #eeeeee;
  border-color: #337ab7;
}
.nav .nav-divider {
  height: 1px;
  margin: 8px 0;
  overflow: hidden;
  background-color: #e5e5e5;
}
.nav > li > a > img {
  max-width: none;
}
.nav-tabs {
  border-bottom: 1px solid #ddd;
}
.nav-tabs > li {
  float: left;
  margin-bottom: -1px;
}
.nav-tabs > li > a {
  margin-right: 2px;
  line-height: 1.42857143;
  border: 1px solid transparent;
  border-radius: 2px 2px 0 0;
}
.nav-tabs > li > a:hover {
  border-color: #eeeeee #eeeeee #ddd;
}
.nav-tabs > li.active > a,
.nav-tabs > li.active > a:hover,
.nav-tabs > li.active > a:focus {
  color: #555555;
  background-color: #fff;
  border: 1px solid #ddd;
  border-bottom-color: transparent;
  cursor: default;
}
.nav-tabs.nav-justified {
  width: 100%;
  border-bottom: 0;
}
.nav-tabs.nav-justified > li {
  float: none;
}
.nav-tabs.nav-justified > li > a {
  text-align: center;
  margin-bottom: 5px;
}
.nav-tabs.nav-justified > .dropdown .dropdown-menu {
  top: auto;
  left: auto;
}
@media (min-width: 768px) {
  .nav-tabs.nav-justified > li {
    display: table-cell;
    width: 1%;
  }
  .nav-tabs.nav-justified > li > a {
    margin-bottom: 0;
  }
}
.nav-tabs.nav-justified > li > a {
  margin-right: 0;
  border-radius: 2px;
}
.nav-tabs.nav-justified > .active > a,
.nav-tabs.nav-justified > .active > a:hover,
.nav-tabs.nav-justified > .active > a:focus {
  border: 1px solid #ddd;
}
@media (min-width: 768px) {
  .nav-tabs.nav-justified > li > a {
    border-bottom: 1px solid #ddd;
    border-radius: 2px 2px 0 0;
  }
  .nav-tabs.nav-justified > .active > a,
  .nav-tabs.nav-justified > .active > a:hover,
  .nav-tabs.nav-justified > .active > a:focus {
    border-bottom-color: #fff;
  }
}
.nav-pills > li {
  float: left;
}
.nav-pills > li > a {
  border-radius: 2px;
}
.nav-pills > li + li {
  margin-left: 2px;
}
.nav-pills > li.active > a,
.nav-pills > li.active > a:hover,
.nav-pills > li.active > a:focus {
  color: #fff;
  background-color: #337ab7;
}
.nav-stacked > li {
  float: none;
}
.nav-stacked > li + li {
  margin-top: 2px;
  margin-left: 0;
}
.nav-justified {
  width: 100%;
}
.nav-justified > li {
  float: none;
}
.nav-justified > li > a {
  text-align: center;
  margin-bottom: 5px;
}
.nav-justified > .dropdown .dropdown-menu {
  top: auto;
  left: auto;
}
@media (min-width: 768px) {
  .nav-justified > li {
    display: table-cell;
    width: 1%;
  }
  .nav-justified > li > a {
    margin-bottom: 0;
  }
}
.nav-tabs-justified {
  border-bottom: 0;
}
.nav-tabs-justified > li > a {
  margin-right: 0;
  border-radius: 2px;
}
.nav-tabs-justified > .active > a,
.nav-tabs-justified > .active > a:hover,
.nav-tabs-justified > .active > a:focus {
  border: 1px solid #ddd;
}
@media (min-width: 768px) {
  .nav-tabs-justified > li > a {
    border-bottom: 1px solid #ddd;
    border-radius: 2px 2px 0 0;
  }
  .nav-tabs-justified > .active > a,
  .nav-tabs-justified > .active > a:hover,
  .nav-tabs-justified > .active > a:focus {
    border-bottom-color: #fff;
  }
}
.tab-content > .tab-pane {
  display: none;
}
.tab-content > .active {
  display: block;
}
.nav-tabs .dropdown-menu {
  margin-top: -1px;
  border-top-right-radius: 0;
  border-top-left-radius: 0;
}
.navbar {
  position: relative;
  min-height: 30px;
  margin-bottom: 18px;
  border: 1px solid transparent;
}
@media (min-width: 541px) {
  .navbar {
    border-radius: 2px;
  }
}
@media (min-width: 541px) {
  .navbar-header {
    float: left;
  }
}
.navbar-collapse {
  overflow-x: visible;
  padding-right: 0px;
  padding-left: 0px;
  border-top: 1px solid transparent;
  box-shadow: inset 0 1px 0 rgba(255, 255, 255, 0.1);
  -webkit-overflow-scrolling: touch;
}
.navbar-collapse.in {
  overflow-y: auto;
}
@media (min-width: 541px) {
  .navbar-collapse {
    width: auto;
    border-top: 0;
    box-shadow: none;
  }
  .navbar-collapse.collapse {
    display: block !important;
    height: auto !important;
    padding-bottom: 0;
    overflow: visible !important;
  }
  .navbar-collapse.in {
    overflow-y: visible;
  }
  .navbar-fixed-top .navbar-collapse,
  .navbar-static-top .navbar-collapse,
  .navbar-fixed-bottom .navbar-collapse {
    padding-left: 0;
    padding-right: 0;
  }
}
.navbar-fixed-top .navbar-collapse,
.navbar-fixed-bottom .navbar-collapse {
  max-height: 340px;
}
@media (max-device-width: 540px) and (orientation: landscape) {
  .navbar-fixed-top .navbar-collapse,
  .navbar-fixed-bottom .navbar-collapse {
    max-height: 200px;
  }
}
.container > .navbar-header,
.container-fluid > .navbar-header,
.container > .navbar-collapse,
.container-fluid > .navbar-collapse {
  margin-right: 0px;
  margin-left: 0px;
}
@media (min-width: 541px) {
  .container > .navbar-header,
  .container-fluid > .navbar-header,
  .container > .navbar-collapse,
  .container-fluid > .navbar-collapse {
    margin-right: 0;
    margin-left: 0;
  }
}
.navbar-static-top {
  z-index: 1000;
  border-width: 0 0 1px;
}
@media (min-width: 541px) {
  .navbar-static-top {
    border-radius: 0;
  }
}
.navbar-fixed-top,
.navbar-fixed-bottom {
  position: fixed;
  right: 0;
  left: 0;
  z-index: 1030;
}
@media (min-width: 541px) {
  .navbar-fixed-top,
  .navbar-fixed-bottom {
    border-radius: 0;
  }
}
.navbar-fixed-top {
  top: 0;
  border-width: 0 0 1px;
}
.navbar-fixed-bottom {
  bottom: 0;
  margin-bottom: 0;
  border-width: 1px 0 0;
}
.navbar-brand {
  float: left;
  padding: 6px 0px;
  font-size: 17px;
  line-height: 18px;
  height: 30px;
}
.navbar-brand:hover,
.navbar-brand:focus {
  text-decoration: none;
}
.navbar-brand > img {
  display: block;
}
@media (min-width: 541px) {
  .navbar > .container .navbar-brand,
  .navbar > .container-fluid .navbar-brand {
    margin-left: 0px;
  }
}
.navbar-toggle {
  position: relative;
  float: right;
  margin-right: 0px;
  padding: 9px 10px;
  margin-top: -2px;
  margin-bottom: -2px;
  background-color: transparent;
  background-image: none;
  border: 1px solid transparent;
  border-radius: 2px;
}
.navbar-toggle:focus {
  outline: 0;
}
.navbar-toggle .icon-bar {
  display: block;
  width: 22px;
  height: 2px;
  border-radius: 1px;
}
.navbar-toggle .icon-bar + .icon-bar {
  margin-top: 4px;
}
@media (min-width: 541px) {
  .navbar-toggle {
    display: none;
  }
}
.navbar-nav {
  margin: 3px 0px;
}
.navbar-nav > li > a {
  padding-top: 10px;
  padding-bottom: 10px;
  line-height: 18px;
}
@media (max-width: 540px) {
  .navbar-nav .open .dropdown-menu {
    position: static;
    float: none;
    width: auto;
    margin-top: 0;
    background-color: transparent;
    border: 0;
    box-shadow: none;
  }
  .navbar-nav .open .dropdown-menu > li > a,
  .navbar-nav .open .dropdown-menu .dropdown-header {
    padding: 5px 15px 5px 25px;
  }
  .navbar-nav .open .dropdown-menu > li > a {
    line-height: 18px;
  }
  .navbar-nav .open .dropdown-menu > li > a:hover,
  .navbar-nav .open .dropdown-menu > li > a:focus {
    background-image: none;
  }
}
@media (min-width: 541px) {
  .navbar-nav {
    float: left;
    margin: 0;
  }
  .navbar-nav > li {
    float: left;
  }
  .navbar-nav > li > a {
    padding-top: 6px;
    padding-bottom: 6px;
  }
}
.navbar-form {
  margin-left: 0px;
  margin-right: 0px;
  padding: 10px 0px;
  border-top: 1px solid transparent;
  border-bottom: 1px solid transparent;
  -webkit-box-shadow: inset 0 1px 0 rgba(255, 255, 255, 0.1), 0 1px 0 rgba(255, 255, 255, 0.1);
  box-shadow: inset 0 1px 0 rgba(255, 255, 255, 0.1), 0 1px 0 rgba(255, 255, 255, 0.1);
  margin-top: -1px;
  margin-bottom: -1px;
}
@media (min-width: 768px) {
  .navbar-form .form-group {
    display: inline-block;
    margin-bottom: 0;
    vertical-align: middle;
  }
  .navbar-form .form-control {
    display: inline-block;
    width: auto;
    vertical-align: middle;
  }
  .navbar-form .form-control-static {
    display: inline-block;
  }
  .navbar-form .input-group {
    display: inline-table;
    vertical-align: middle;
  }
  .navbar-form .input-group .input-group-addon,
  .navbar-form .input-group .input-group-btn,
  .navbar-form .input-group .form-control {
    width: auto;
  }
  .navbar-form .input-group > .form-control {
    width: 100%;
  }
  .navbar-form .control-label {
    margin-bottom: 0;
    vertical-align: middle;
  }
  .navbar-form .radio,
  .navbar-form .checkbox {
    display: inline-block;
    margin-top: 0;
    margin-bottom: 0;
    vertical-align: middle;
  }
  .navbar-form .radio label,
  .navbar-form .checkbox label {
    padding-left: 0;
  }
  .navbar-form .radio input[type="radio"],
  .navbar-form .checkbox input[type="checkbox"] {
    position: relative;
    margin-left: 0;
  }
  .navbar-form .has-feedback .form-control-feedback {
    top: 0;
  }
}
@media (max-width: 540px) {
  .navbar-form .form-group {
    margin-bottom: 5px;
  }
  .navbar-form .form-group:last-child {
    margin-bottom: 0;
  }
}
@media (min-width: 541px) {
  .navbar-form {
    width: auto;
    border: 0;
    margin-left: 0;
    margin-right: 0;
    padding-top: 0;
    padding-bottom: 0;
    -webkit-box-shadow: none;
    box-shadow: none;
  }
}
.navbar-nav > li > .dropdown-menu {
  margin-top: 0;
  border-top-right-radius: 0;
  border-top-left-radius: 0;
}
.navbar-fixed-bottom .navbar-nav > li > .dropdown-menu {
  margin-bottom: 0;
  border-top-right-radius: 2px;
  border-top-left-radius: 2px;
  border-bottom-right-radius: 0;
  border-bottom-left-radius: 0;
}
.navbar-btn {
  margin-top: -1px;
  margin-bottom: -1px;
}
.navbar-btn.btn-sm {
  margin-top: 0px;
  margin-bottom: 0px;
}
.navbar-btn.btn-xs {
  margin-top: 4px;
  margin-bottom: 4px;
}
.navbar-text {
  margin-top: 6px;
  margin-bottom: 6px;
}
@media (min-width: 541px) {
  .navbar-text {
    float: left;
    margin-left: 0px;
    margin-right: 0px;
  }
}
@media (min-width: 541px) {
  .navbar-left {
    float: left !important;
    float: left;
  }
  .navbar-right {
    float: right !important;
    float: right;
    margin-right: 0px;
  }
  .navbar-right ~ .navbar-right {
    margin-right: 0;
  }
}
.navbar-default {
  background-color: #f8f8f8;
  border-color: #e7e7e7;
}
.navbar-default .navbar-brand {
  color: #777;
}
.navbar-default .navbar-brand:hover,
.navbar-default .navbar-brand:focus {
  color: #5e5e5e;
  background-color: transparent;
}
.navbar-default .navbar-text {
  color: #777;
}
.navbar-default .navbar-nav > li > a {
  color: #777;
}
.navbar-default .navbar-nav > li > a:hover,
.navbar-default .navbar-nav > li > a:focus {
  color: #333;
  background-color: transparent;
}
.navbar-default .navbar-nav > .active > a,
.navbar-default .navbar-nav > .active > a:hover,
.navbar-default .navbar-nav > .active > a:focus {
  color: #555;
  background-color: #e7e7e7;
}
.navbar-default .navbar-nav > .disabled > a,
.navbar-default .navbar-nav > .disabled > a:hover,
.navbar-default .navbar-nav > .disabled > a:focus {
  color: #ccc;
  background-color: transparent;
}
.navbar-default .navbar-toggle {
  border-color: #ddd;
}
.navbar-default .navbar-toggle:hover,
.navbar-default .navbar-toggle:focus {
  background-color: #ddd;
}
.navbar-default .navbar-toggle .icon-bar {
  background-color: #888;
}
.navbar-default .navbar-collapse,
.navbar-default .navbar-form {
  border-color: #e7e7e7;
}
.navbar-default .navbar-nav > .open > a,
.navbar-default .navbar-nav > .open > a:hover,
.navbar-default .navbar-nav > .open > a:focus {
  background-color: #e7e7e7;
  color: #555;
}
@media (max-width: 540px) {
  .navbar-default .navbar-nav .open .dropdown-menu > li > a {
    color: #777;
  }
  .navbar-default .navbar-nav .open .dropdown-menu > li > a:hover,
  .navbar-default .navbar-nav .open .dropdown-menu > li > a:focus {
    color: #333;
    background-color: transparent;
  }
  .navbar-default .navbar-nav .open .dropdown-menu > .active > a,
  .navbar-default .navbar-nav .open .dropdown-menu > .active > a:hover,
  .navbar-default .navbar-nav .open .dropdown-menu > .active > a:focus {
    color: #555;
    background-color: #e7e7e7;
  }
  .navbar-default .navbar-nav .open .dropdown-menu > .disabled > a,
  .navbar-default .navbar-nav .open .dropdown-menu > .disabled > a:hover,
  .navbar-default .navbar-nav .open .dropdown-menu > .disabled > a:focus {
    color: #ccc;
    background-color: transparent;
  }
}
.navbar-default .navbar-link {
  color: #777;
}
.navbar-default .navbar-link:hover {
  color: #333;
}
.navbar-default .btn-link {
  color: #777;
}
.navbar-default .btn-link:hover,
.navbar-default .btn-link:focus {
  color: #333;
}
.navbar-default .btn-link[disabled]:hover,
fieldset[disabled] .navbar-default .btn-link:hover,
.navbar-default .btn-link[disabled]:focus,
fieldset[disabled] .navbar-default .btn-link:focus {
  color: #ccc;
}
.navbar-inverse {
  background-color: #222;
  border-color: #080808;
}
.navbar-inverse .navbar-brand {
  color: #9d9d9d;
}
.navbar-inverse .navbar-brand:hover,
.navbar-inverse .navbar-brand:focus {
  color: #fff;
  background-color: transparent;
}
.navbar-inverse .navbar-text {
  color: #9d9d9d;
}
.navbar-inverse .navbar-nav > li > a {
  color: #9d9d9d;
}
.navbar-inverse .navbar-nav > li > a:hover,
.navbar-inverse .navbar-nav > li > a:focus {
  color: #fff;
  background-color: transparent;
}
.navbar-inverse .navbar-nav > .active > a,
.navbar-inverse .navbar-nav > .active > a:hover,
.navbar-inverse .navbar-nav > .active > a:focus {
  color: #fff;
  background-color: #080808;
}
.navbar-inverse .navbar-nav > .disabled > a,
.navbar-inverse .navbar-nav > .disabled > a:hover,
.navbar-inverse .navbar-nav > .disabled > a:focus {
  color: #444;
  background-color: transparent;
}
.navbar-inverse .navbar-toggle {
  border-color: #333;
}
.navbar-inverse .navbar-toggle:hover,
.navbar-inverse .navbar-toggle:focus {
  background-color: #333;
}
.navbar-inverse .navbar-toggle .icon-bar {
  background-color: #fff;
}
.navbar-inverse .navbar-collapse,
.navbar-inverse .navbar-form {
  border-color: #101010;
}
.navbar-inverse .navbar-nav > .open > a,
.navbar-inverse .navbar-nav > .open > a:hover,
.navbar-inverse .navbar-nav > .open > a:focus {
  background-color: #080808;
  color: #fff;
}
@media (max-width: 540px) {
  .navbar-inverse .navbar-nav .open .dropdown-menu > .dropdown-header {
    border-color: #080808;
  }
  .navbar-inverse .navbar-nav .open .dropdown-menu .divider {
    background-color: #080808;
  }
  .navbar-inverse .navbar-nav .open .dropdown-menu > li > a {
    color: #9d9d9d;
  }
  .navbar-inverse .navbar-nav .open .dropdown-menu > li > a:hover,
  .navbar-inverse .navbar-nav .open .dropdown-menu > li > a:focus {
    color: #fff;
    background-color: transparent;
  }
  .navbar-inverse .navbar-nav .open .dropdown-menu > .active > a,
  .navbar-inverse .navbar-nav .open .dropdown-menu > .active > a:hover,
  .navbar-inverse .navbar-nav .open .dropdown-menu > .active > a:focus {
    color: #fff;
    background-color: #080808;
  }
  .navbar-inverse .navbar-nav .open .dropdown-menu > .disabled > a,
  .navbar-inverse .navbar-nav .open .dropdown-menu > .disabled > a:hover,
  .navbar-inverse .navbar-nav .open .dropdown-menu > .disabled > a:focus {
    color: #444;
    background-color: transparent;
  }
}
.navbar-inverse .navbar-link {
  color: #9d9d9d;
}
.navbar-inverse .navbar-link:hover {
  color: #fff;
}
.navbar-inverse .btn-link {
  color: #9d9d9d;
}
.navbar-inverse .btn-link:hover,
.navbar-inverse .btn-link:focus {
  color: #fff;
}
.navbar-inverse .btn-link[disabled]:hover,
fieldset[disabled] .navbar-inverse .btn-link:hover,
.navbar-inverse .btn-link[disabled]:focus,
fieldset[disabled] .navbar-inverse .btn-link:focus {
  color: #444;
}
.breadcrumb {
  padding: 8px 15px;
  margin-bottom: 18px;
  list-style: none;
  background-color: #f5f5f5;
  border-radius: 2px;
}
.breadcrumb > li {
  display: inline-block;
}
.breadcrumb > li + li:before {
  content: "/\00a0";
  padding: 0 5px;
  color: #5e5e5e;
}
.breadcrumb > .active {
  color: #777777;
}
.pagination {
  display: inline-block;
  padding-left: 0;
  margin: 18px 0;
  border-radius: 2px;
}
.pagination > li {
  display: inline;
}
.pagination > li > a,
.pagination > li > span {
  position: relative;
  float: left;
  padding: 6px 12px;
  line-height: 1.42857143;
  text-decoration: none;
  color: #337ab7;
  background-color: #fff;
  border: 1px solid #ddd;
  margin-left: -1px;
}
.pagination > li:first-child > a,
.pagination > li:first-child > span {
  margin-left: 0;
  border-bottom-left-radius: 2px;
  border-top-left-radius: 2px;
}
.pagination > li:last-child > a,
.pagination > li:last-child > span {
  border-bottom-right-radius: 2px;
  border-top-right-radius: 2px;
}
.pagination > li > a:hover,
.pagination > li > span:hover,
.pagination > li > a:focus,
.pagination > li > span:focus {
  z-index: 2;
  color: #23527c;
  background-color: #eeeeee;
  border-color: #ddd;
}
.pagination > .active > a,
.pagination > .active > span,
.pagination > .active > a:hover,
.pagination > .active > span:hover,
.pagination > .active > a:focus,
.pagination > .active > span:focus {
  z-index: 3;
  color: #fff;
  background-color: #337ab7;
  border-color: #337ab7;
  cursor: default;
}
.pagination > .disabled > span,
.pagination > .disabled > span:hover,
.pagination > .disabled > span:focus,
.pagination > .disabled > a,
.pagination > .disabled > a:hover,
.pagination > .disabled > a:focus {
  color: #777777;
  background-color: #fff;
  border-color: #ddd;
  cursor: not-allowed;
}
.pagination-lg > li > a,
.pagination-lg > li > span {
  padding: 10px 16px;
  font-size: 17px;
  line-height: 1.3333333;
}
.pagination-lg > li:first-child > a,
.pagination-lg > li:first-child > span {
  border-bottom-left-radius: 3px;
  border-top-left-radius: 3px;
}
.pagination-lg > li:last-child > a,
.pagination-lg > li:last-child > span {
  border-bottom-right-radius: 3px;
  border-top-right-radius: 3px;
}
.pagination-sm > li > a,
.pagination-sm > li > span {
  padding: 5px 10px;
  font-size: 12px;
  line-height: 1.5;
}
.pagination-sm > li:first-child > a,
.pagination-sm > li:first-child > span {
  border-bottom-left-radius: 1px;
  border-top-left-radius: 1px;
}
.pagination-sm > li:last-child > a,
.pagination-sm > li:last-child > span {
  border-bottom-right-radius: 1px;
  border-top-right-radius: 1px;
}
.pager {
  padding-left: 0;
  margin: 18px 0;
  list-style: none;
  text-align: center;
}
.pager li {
  display: inline;
}
.pager li > a,
.pager li > span {
  display: inline-block;
  padding: 5px 14px;
  background-color: #fff;
  border: 1px solid #ddd;
  border-radius: 15px;
}
.pager li > a:hover,
.pager li > a:focus {
  text-decoration: none;
  background-color: #eeeeee;
}
.pager .next > a,
.pager .next > span {
  float: right;
}
.pager .previous > a,
.pager .previous > span {
  float: left;
}
.pager .disabled > a,
.pager .disabled > a:hover,
.pager .disabled > a:focus,
.pager .disabled > span {
  color: #777777;
  background-color: #fff;
  cursor: not-allowed;
}
.label {
  display: inline;
  padding: .2em .6em .3em;
  font-size: 75%;
  font-weight: bold;
  line-height: 1;
  color: #fff;
  text-align: center;
  white-space: nowrap;
  vertical-align: baseline;
  border-radius: .25em;
}
a.label:hover,
a.label:focus {
  color: #fff;
  text-decoration: none;
  cursor: pointer;
}
.label:empty {
  display: none;
}
.btn .label {
  position: relative;
  top: -1px;
}
.label-default {
  background-color: #777777;
}
.label-default[href]:hover,
.label-default[href]:focus {
  background-color: #5e5e5e;
}
.label-primary {
  background-color: #337ab7;
}
.label-primary[href]:hover,
.label-primary[href]:focus {
  background-color: #286090;
}
.label-success {
  background-color: #5cb85c;
}
.label-success[href]:hover,
.label-success[href]:focus {
  background-color: #449d44;
}
.label-info {
  background-color: #5bc0de;
}
.label-info[href]:hover,
.label-info[href]:focus {
  background-color: #31b0d5;
}
.label-warning {
  background-color: #f0ad4e;
}
.label-warning[href]:hover,
.label-warning[href]:focus {
  background-color: #ec971f;
}
.label-danger {
  background-color: #d9534f;
}
.label-danger[href]:hover,
.label-danger[href]:focus {
  background-color: #c9302c;
}
.badge {
  display: inline-block;
  min-width: 10px;
  padding: 3px 7px;
  font-size: 12px;
  font-weight: bold;
  color: #fff;
  line-height: 1;
  vertical-align: middle;
  white-space: nowrap;
  text-align: center;
  background-color: #777777;
  border-radius: 10px;
}
.badge:empty {
  display: none;
}
.btn .badge {
  position: relative;
  top: -1px;
}
.btn-xs .badge,
.btn-group-xs > .btn .badge {
  top: 0;
  padding: 1px 5px;
}
a.badge:hover,
a.badge:focus {
  color: #fff;
  text-decoration: none;
  cursor: pointer;
}
.list-group-item.active > .badge,
.nav-pills > .active > a > .badge {
  color: #337ab7;
  background-color: #fff;
}
.list-group-item > .badge {
  float: right;
}
.list-group-item > .badge + .badge {
  margin-right: 5px;
}
.nav-pills > li > a > .badge {
  margin-left: 3px;
}
.jumbotron {
  padding-top: 30px;
  padding-bottom: 30px;
  margin-bottom: 30px;
  color: inherit;
  background-color: #eeeeee;
}
.jumbotron h1,
.jumbotron .h1 {
  color: inherit;
}
.jumbotron p {
  margin-bottom: 15px;
  font-size: 20px;
  font-weight: 200;
}
.jumbotron > hr {
  border-top-color: #d5d5d5;
}
.container .jumbotron,
.container-fluid .jumbotron {
  border-radius: 3px;
  padding-left: 0px;
  padding-right: 0px;
}
.jumbotron .container {
  max-width: 100%;
}
@media screen and (min-width: 768px) {
  .jumbotron {
    padding-top: 48px;
    padding-bottom: 48px;
  }
  .container .jumbotron,
  .container-fluid .jumbotron {
    padding-left: 60px;
    padding-right: 60px;
  }
  .jumbotron h1,
  .jumbotron .h1 {
    font-size: 59px;
  }
}
.thumbnail {
  display: block;
  padding: 4px;
  margin-bottom: 18px;
  line-height: 1.42857143;
  background-color: #fff;
  border: 1px solid #ddd;
  border-radius: 2px;
  -webkit-transition: border 0.2s ease-in-out;
  -o-transition: border 0.2s ease-in-out;
  transition: border 0.2s ease-in-out;
}
.thumbnail > img,
.thumbnail a > img {
  margin-left: auto;
  margin-right: auto;
}
a.thumbnail:hover,
a.thumbnail:focus,
a.thumbnail.active {
  border-color: #337ab7;
}
.thumbnail .caption {
  padding: 9px;
  color: #000;
}
.alert {
  padding: 15px;
  margin-bottom: 18px;
  border: 1px solid transparent;
  border-radius: 2px;
}
.alert h4 {
  margin-top: 0;
  color: inherit;
}
.alert .alert-link {
  font-weight: bold;
}
.alert > p,
.alert > ul {
  margin-bottom: 0;
}
.alert > p + p {
  margin-top: 5px;
}
.alert-dismissable,
.alert-dismissible {
  padding-right: 35px;
}
.alert-dismissable .close,
.alert-dismissible .close {
  position: relative;
  top: -2px;
  right: -21px;
  color: inherit;
}
.alert-success {
  background-color: #dff0d8;
  border-color: #d6e9c6;
  color: #3c763d;
}
.alert-success hr {
  border-top-color: #c9e2b3;
}
.alert-success .alert-link {
  color: #2b542c;
}
.alert-info {
  background-color: #d9edf7;
  border-color: #bce8f1;
  color: #31708f;
}
.alert-info hr {
  border-top-color: #a6e1ec;
}
.alert-info .alert-link {
  color: #245269;
}
.alert-warning {
  background-color: #fcf8e3;
  border-color: #faebcc;
  color: #8a6d3b;
}
.alert-warning hr {
  border-top-color: #f7e1b5;
}
.alert-warning .alert-link {
  color: #66512c;
}
.alert-danger {
  background-color: #f2dede;
  border-color: #ebccd1;
  color: #a94442;
}
.alert-danger hr {
  border-top-color: #e4b9c0;
}
.alert-danger .alert-link {
  color: #843534;
}
@-webkit-keyframes progress-bar-stripes {
  from {
    background-position: 40px 0;
  }
  to {
    background-position: 0 0;
  }
}
@keyframes progress-bar-stripes {
  from {
    background-position: 40px 0;
  }
  to {
    background-position: 0 0;
  }
}
.progress {
  overflow: hidden;
  height: 18px;
  margin-bottom: 18px;
  background-color: #f5f5f5;
  border-radius: 2px;
  -webkit-box-shadow: inset 0 1px 2px rgba(0, 0, 0, 0.1);
  box-shadow: inset 0 1px 2px rgba(0, 0, 0, 0.1);
}
.progress-bar {
  float: left;
  width: 0%;
  height: 100%;
  font-size: 12px;
  line-height: 18px;
  color: #fff;
  text-align: center;
  background-color: #337ab7;
  -webkit-box-shadow: inset 0 -1px 0 rgba(0, 0, 0, 0.15);
  box-shadow: inset 0 -1px 0 rgba(0, 0, 0, 0.15);
  -webkit-transition: width 0.6s ease;
  -o-transition: width 0.6s ease;
  transition: width 0.6s ease;
}
.progress-striped .progress-bar,
.progress-bar-striped {
  background-image: -webkit-linear-gradient(45deg, rgba(255, 255, 255, 0.15) 25%, transparent 25%, transparent 50%, rgba(255, 255, 255, 0.15) 50%, rgba(255, 255, 255, 0.15) 75%, transparent 75%, transparent);
  background-image: -o-linear-gradient(45deg, rgba(255, 255, 255, 0.15) 25%, transparent 25%, transparent 50%, rgba(255, 255, 255, 0.15) 50%, rgba(255, 255, 255, 0.15) 75%, transparent 75%, transparent);
  background-image: linear-gradient(45deg, rgba(255, 255, 255, 0.15) 25%, transparent 25%, transparent 50%, rgba(255, 255, 255, 0.15) 50%, rgba(255, 255, 255, 0.15) 75%, transparent 75%, transparent);
  background-size: 40px 40px;
}
.progress.active .progress-bar,
.progress-bar.active {
  -webkit-animation: progress-bar-stripes 2s linear infinite;
  -o-animation: progress-bar-stripes 2s linear infinite;
  animation: progress-bar-stripes 2s linear infinite;
}
.progress-bar-success {
  background-color: #5cb85c;
}
.progress-striped .progress-bar-success {
  background-image: -webkit-linear-gradient(45deg, rgba(255, 255, 255, 0.15) 25%, transparent 25%, transparent 50%, rgba(255, 255, 255, 0.15) 50%, rgba(255, 255, 255, 0.15) 75%, transparent 75%, transparent);
  background-image: -o-linear-gradient(45deg, rgba(255, 255, 255, 0.15) 25%, transparent 25%, transparent 50%, rgba(255, 255, 255, 0.15) 50%, rgba(255, 255, 255, 0.15) 75%, transparent 75%, transparent);
  background-image: linear-gradient(45deg, rgba(255, 255, 255, 0.15) 25%, transparent 25%, transparent 50%, rgba(255, 255, 255, 0.15) 50%, rgba(255, 255, 255, 0.15) 75%, transparent 75%, transparent);
}
.progress-bar-info {
  background-color: #5bc0de;
}
.progress-striped .progress-bar-info {
  background-image: -webkit-linear-gradient(45deg, rgba(255, 255, 255, 0.15) 25%, transparent 25%, transparent 50%, rgba(255, 255, 255, 0.15) 50%, rgba(255, 255, 255, 0.15) 75%, transparent 75%, transparent);
  background-image: -o-linear-gradient(45deg, rgba(255, 255, 255, 0.15) 25%, transparent 25%, transparent 50%, rgba(255, 255, 255, 0.15) 50%, rgba(255, 255, 255, 0.15) 75%, transparent 75%, transparent);
  background-image: linear-gradient(45deg, rgba(255, 255, 255, 0.15) 25%, transparent 25%, transparent 50%, rgba(255, 255, 255, 0.15) 50%, rgba(255, 255, 255, 0.15) 75%, transparent 75%, transparent);
}
.progress-bar-warning {
  background-color: #f0ad4e;
}
.progress-striped .progress-bar-warning {
  background-image: -webkit-linear-gradient(45deg, rgba(255, 255, 255, 0.15) 25%, transparent 25%, transparent 50%, rgba(255, 255, 255, 0.15) 50%, rgba(255, 255, 255, 0.15) 75%, transparent 75%, transparent);
  background-image: -o-linear-gradient(45deg, rgba(255, 255, 255, 0.15) 25%, transparent 25%, transparent 50%, rgba(255, 255, 255, 0.15) 50%, rgba(255, 255, 255, 0.15) 75%, transparent 75%, transparent);
  background-image: linear-gradient(45deg, rgba(255, 255, 255, 0.15) 25%, transparent 25%, transparent 50%, rgba(255, 255, 255, 0.15) 50%, rgba(255, 255, 255, 0.15) 75%, transparent 75%, transparent);
}
.progress-bar-danger {
  background-color: #d9534f;
}
.progress-striped .progress-bar-danger {
  background-image: -webkit-linear-gradient(45deg, rgba(255, 255, 255, 0.15) 25%, transparent 25%, transparent 50%, rgba(255, 255, 255, 0.15) 50%, rgba(255, 255, 255, 0.15) 75%, transparent 75%, transparent);
  background-image: -o-linear-gradient(45deg, rgba(255, 255, 255, 0.15) 25%, transparent 25%, transparent 50%, rgba(255, 255, 255, 0.15) 50%, rgba(255, 255, 255, 0.15) 75%, transparent 75%, transparent);
  background-image: linear-gradient(45deg, rgba(255, 255, 255, 0.15) 25%, transparent 25%, transparent 50%, rgba(255, 255, 255, 0.15) 50%, rgba(255, 255, 255, 0.15) 75%, transparent 75%, transparent);
}
.media {
  margin-top: 15px;
}
.media:first-child {
  margin-top: 0;
}
.media,
.media-body {
  zoom: 1;
  overflow: hidden;
}
.media-body {
  width: 10000px;
}
.media-object {
  display: block;
}
.media-object.img-thumbnail {
  max-width: none;
}
.media-right,
.media > .pull-right {
  padding-left: 10px;
}
.media-left,
.media > .pull-left {
  padding-right: 10px;
}
.media-left,
.media-right,
.media-body {
  display: table-cell;
  vertical-align: top;
}
.media-middle {
  vertical-align: middle;
}
.media-bottom {
  vertical-align: bottom;
}
.media-heading {
  margin-top: 0;
  margin-bottom: 5px;
}
.media-list {
  padding-left: 0;
  list-style: none;
}
.list-group {
  margin-bottom: 20px;
  padding-left: 0;
}
.list-group-item {
  position: relative;
  display: block;
  padding: 10px 15px;
  margin-bottom: -1px;
  background-color: #fff;
  border: 1px solid #ddd;
}
.list-group-item:first-child {
  border-top-right-radius: 2px;
  border-top-left-radius: 2px;
}
.list-group-item:last-child {
  margin-bottom: 0;
  border-bottom-right-radius: 2px;
  border-bottom-left-radius: 2px;
}
a.list-group-item,
button.list-group-item {
  color: #555;
}
a.list-group-item .list-group-item-heading,
button.list-group-item .list-group-item-heading {
  color: #333;
}
a.list-group-item:hover,
button.list-group-item:hover,
a.list-group-item:focus,
button.list-group-item:focus {
  text-decoration: none;
  color: #555;
  background-color: #f5f5f5;
}
button.list-group-item {
  width: 100%;
  text-align: left;
}
.list-group-item.disabled,
.list-group-item.disabled:hover,
.list-group-item.disabled:focus {
  background-color: #eeeeee;
  color: #777777;
  cursor: not-allowed;
}
.list-group-item.disabled .list-group-item-heading,
.list-group-item.disabled:hover .list-group-item-heading,
.list-group-item.disabled:focus .list-group-item-heading {
  color: inherit;
}
.list-group-item.disabled .list-group-item-text,
.list-group-item.disabled:hover .list-group-item-text,
.list-group-item.disabled:focus .list-group-item-text {
  color: #777777;
}
.list-group-item.active,
.list-group-item.active:hover,
.list-group-item.active:focus {
  z-index: 2;
  color: #fff;
  background-color: #337ab7;
  border-color: #337ab7;
}
.list-group-item.active .list-group-item-heading,
.list-group-item.active:hover .list-group-item-heading,
.list-group-item.active:focus .list-group-item-heading,
.list-group-item.active .list-group-item-heading > small,
.list-group-item.active:hover .list-group-item-heading > small,
.list-group-item.active:focus .list-group-item-heading > small,
.list-group-item.active .list-group-item-heading > .small,
.list-group-item.active:hover .list-group-item-heading > .small,
.list-group-item.active:focus .list-group-item-heading > .small {
  color: inherit;
}
.list-group-item.active .list-group-item-text,
.list-group-item.active:hover .list-group-item-text,
.list-group-item.active:focus .list-group-item-text {
  color: #c7ddef;
}
.list-group-item-success {
  color: #3c763d;
  background-color: #dff0d8;
}
a.list-group-item-success,
button.list-group-item-success {
  color: #3c763d;
}
a.list-group-item-success .list-group-item-heading,
button.list-group-item-success .list-group-item-heading {
  color: inherit;
}
a.list-group-item-success:hover,
button.list-group-item-success:hover,
a.list-group-item-success:focus,
button.list-group-item-success:focus {
  color: #3c763d;
  background-color: #d0e9c6;
}
a.list-group-item-success.active,
button.list-group-item-success.active,
a.list-group-item-success.active:hover,
button.list-group-item-success.active:hover,
a.list-group-item-success.active:focus,
button.list-group-item-success.active:focus {
  color: #fff;
  background-color: #3c763d;
  border-color: #3c763d;
}
.list-group-item-info {
  color: #31708f;
  background-color: #d9edf7;
}
a.list-group-item-info,
button.list-group-item-info {
  color: #31708f;
}
a.list-group-item-info .list-group-item-heading,
button.list-group-item-info .list-group-item-heading {
  color: inherit;
}
a.list-group-item-info:hover,
button.list-group-item-info:hover,
a.list-group-item-info:focus,
button.list-group-item-info:focus {
  color: #31708f;
  background-color: #c4e3f3;
}
a.list-group-item-info.active,
button.list-group-item-info.active,
a.list-group-item-info.active:hover,
button.list-group-item-info.active:hover,
a.list-group-item-info.active:focus,
button.list-group-item-info.active:focus {
  color: #fff;
  background-color: #31708f;
  border-color: #31708f;
}
.list-group-item-warning {
  color: #8a6d3b;
  background-color: #fcf8e3;
}
a.list-group-item-warning,
button.list-group-item-warning {
  color: #8a6d3b;
}
a.list-group-item-warning .list-group-item-heading,
button.list-group-item-warning .list-group-item-heading {
  color: inherit;
}
a.list-group-item-warning:hover,
button.list-group-item-warning:hover,
a.list-group-item-warning:focus,
button.list-group-item-warning:focus {
  color: #8a6d3b;
  background-color: #faf2cc;
}
a.list-group-item-warning.active,
button.list-group-item-warning.active,
a.list-group-item-warning.active:hover,
button.list-group-item-warning.active:hover,
a.list-group-item-warning.active:focus,
button.list-group-item-warning.active:focus {
  color: #fff;
  background-color: #8a6d3b;
  border-color: #8a6d3b;
}
.list-group-item-danger {
  color: #a94442;
  background-color: #f2dede;
}
a.list-group-item-danger,
button.list-group-item-danger {
  color: #a94442;
}
a.list-group-item-danger .list-group-item-heading,
button.list-group-item-danger .list-group-item-heading {
  color: inherit;
}
a.list-group-item-danger:hover,
button.list-group-item-danger:hover,
a.list-group-item-danger:focus,
button.list-group-item-danger:focus {
  color: #a94442;
  background-color: #ebcccc;
}
a.list-group-item-danger.active,
button.list-group-item-danger.active,
a.list-group-item-danger.active:hover,
button.list-group-item-danger.active:hover,
a.list-group-item-danger.active:focus,
button.list-group-item-danger.active:focus {
  color: #fff;
  background-color: #a94442;
  border-color: #a94442;
}
.list-group-item-heading {
  margin-top: 0;
  margin-bottom: 5px;
}
.list-group-item-text {
  margin-bottom: 0;
  line-height: 1.3;
}
.panel {
  margin-bottom: 18px;
  background-color: #fff;
  border: 1px solid transparent;
  border-radius: 2px;
  -webkit-box-shadow: 0 1px 1px rgba(0, 0, 0, 0.05);
  box-shadow: 0 1px 1px rgba(0, 0, 0, 0.05);
}
.panel-body {
  padding: 15px;
}
.panel-heading {
  padding: 10px 15px;
  border-bottom: 1px solid transparent;
  border-top-right-radius: 1px;
  border-top-left-radius: 1px;
}
.panel-heading > .dropdown .dropdown-toggle {
  color: inherit;
}
.panel-title {
  margin-top: 0;
  margin-bottom: 0;
  font-size: 15px;
  color: inherit;
}
.panel-title > a,
.panel-title > small,
.panel-title > .small,
.panel-title > small > a,
.panel-title > .small > a {
  color: inherit;
}
.panel-footer {
  padding: 10px 15px;
  background-color: #f5f5f5;
  border-top: 1px solid #ddd;
  border-bottom-right-radius: 1px;
  border-bottom-left-radius: 1px;
}
.panel > .list-group,
.panel > .panel-collapse > .list-group {
  margin-bottom: 0;
}
.panel > .list-group .list-group-item,
.panel > .panel-collapse > .list-group .list-group-item {
  border-width: 1px 0;
  border-radius: 0;
}
.panel > .list-group:first-child .list-group-item:first-child,
.panel > .panel-collapse > .list-group:first-child .list-group-item:first-child {
  border-top: 0;
  border-top-right-radius: 1px;
  border-top-left-radius: 1px;
}
.panel > .list-group:last-child .list-group-item:last-child,
.panel > .panel-collapse > .list-group:last-child .list-group-item:last-child {
  border-bottom: 0;
  border-bottom-right-radius: 1px;
  border-bottom-left-radius: 1px;
}
.panel > .panel-heading + .panel-collapse > .list-group .list-group-item:first-child {
  border-top-right-radius: 0;
  border-top-left-radius: 0;
}
.panel-heading + .list-group .list-group-item:first-child {
  border-top-width: 0;
}
.list-group + .panel-footer {
  border-top-width: 0;
}
.panel > .table,
.panel > .table-responsive > .table,
.panel > .panel-collapse > .table {
  margin-bottom: 0;
}
.panel > .table caption,
.panel > .table-responsive > .table caption,
.panel > .panel-collapse > .table caption {
  padding-left: 15px;
  padding-right: 15px;
}
.panel > .table:first-child,
.panel > .table-responsive:first-child > .table:first-child {
  border-top-right-radius: 1px;
  border-top-left-radius: 1px;
}
.panel > .table:first-child > thead:first-child > tr:first-child,
.panel > .table-responsive:first-child > .table:first-child > thead:first-child > tr:first-child,
.panel > .table:first-child > tbody:first-child > tr:first-child,
.panel > .table-responsive:first-child > .table:first-child > tbody:first-child > tr:first-child {
  border-top-left-radius: 1px;
  border-top-right-radius: 1px;
}
.panel > .table:first-child > thead:first-child > tr:first-child td:first-child,
.panel > .table-responsive:first-child > .table:first-child > thead:first-child > tr:first-child td:first-child,
.panel > .table:first-child > tbody:first-child > tr:first-child td:first-child,
.panel > .table-responsive:first-child > .table:first-child > tbody:first-child > tr:first-child td:first-child,
.panel > .table:first-child > thead:first-child > tr:first-child th:first-child,
.panel > .table-responsive:first-child > .table:first-child > thead:first-child > tr:first-child th:first-child,
.panel > .table:first-child > tbody:first-child > tr:first-child th:first-child,
.panel > .table-responsive:first-child > .table:first-child > tbody:first-child > tr:first-child th:first-child {
  border-top-left-radius: 1px;
}
.panel > .table:first-child > thead:first-child > tr:first-child td:last-child,
.panel > .table-responsive:first-child > .table:first-child > thead:first-child > tr:first-child td:last-child,
.panel > .table:first-child > tbody:first-child > tr:first-child td:last-child,
.panel > .table-responsive:first-child > .table:first-child > tbody:first-child > tr:first-child td:last-child,
.panel > .table:first-child > thead:first-child > tr:first-child th:last-child,
.panel > .table-responsive:first-child > .table:first-child > thead:first-child > tr:first-child th:last-child,
.panel > .table:first-child > tbody:first-child > tr:first-child th:last-child,
.panel > .table-responsive:first-child > .table:first-child > tbody:first-child > tr:first-child th:last-child {
  border-top-right-radius: 1px;
}
.panel > .table:last-child,
.panel > .table-responsive:last-child > .table:last-child {
  border-bottom-right-radius: 1px;
  border-bottom-left-radius: 1px;
}
.panel > .table:last-child > tbody:last-child > tr:last-child,
.panel > .table-responsive:last-child > .table:last-child > tbody:last-child > tr:last-child,
.panel > .table:last-child > tfoot:last-child > tr:last-child,
.panel > .table-responsive:last-child > .table:last-child > tfoot:last-child > tr:last-child {
  border-bottom-left-radius: 1px;
  border-bottom-right-radius: 1px;
}
.panel > .table:last-child > tbody:last-child > tr:last-child td:first-child,
.panel > .table-responsive:last-child > .table:last-child > tbody:last-child > tr:last-child td:first-child,
.panel > .table:last-child > tfoot:last-child > tr:last-child td:first-child,
.panel > .table-responsive:last-child > .table:last-child > tfoot:last-child > tr:last-child td:first-child,
.panel > .table:last-child > tbody:last-child > tr:last-child th:first-child,
.panel > .table-responsive:last-child > .table:last-child > tbody:last-child > tr:last-child th:first-child,
.panel > .table:last-child > tfoot:last-child > tr:last-child th:first-child,
.panel > .table-responsive:last-child > .table:last-child > tfoot:last-child > tr:last-child th:first-child {
  border-bottom-left-radius: 1px;
}
.panel > .table:last-child > tbody:last-child > tr:last-child td:last-child,
.panel > .table-responsive:last-child > .table:last-child > tbody:last-child > tr:last-child td:last-child,
.panel > .table:last-child > tfoot:last-child > tr:last-child td:last-child,
.panel > .table-responsive:last-child > .table:last-child > tfoot:last-child > tr:last-child td:last-child,
.panel > .table:last-child > tbody:last-child > tr:last-child th:last-child,
.panel > .table-responsive:last-child > .table:last-child > tbody:last-child > tr:last-child th:last-child,
.panel > .table:last-child > tfoot:last-child > tr:last-child th:last-child,
.panel > .table-responsive:last-child > .table:last-child > tfoot:last-child > tr:last-child th:last-child {
  border-bottom-right-radius: 1px;
}
.panel > .panel-body + .table,
.panel > .panel-body + .table-responsive,
.panel > .table + .panel-body,
.panel > .table-responsive + .panel-body {
  border-top: 1px solid #ddd;
}
.panel > .table > tbody:first-child > tr:first-child th,
.panel > .table > tbody:first-child > tr:first-child td {
  border-top: 0;
}
.panel > .table-bordered,
.panel > .table-responsive > .table-bordered {
  border: 0;
}
.panel > .table-bordered > thead > tr > th:first-child,
.panel > .table-responsive > .table-bordered > thead > tr > th:first-child,
.panel > .table-bordered > tbody > tr > th:first-child,
.panel > .table-responsive > .table-bordered > tbody > tr > th:first-child,
.panel > .table-bordered > tfoot > tr > th:first-child,
.panel > .table-responsive > .table-bordered > tfoot > tr > th:first-child,
.panel > .table-bordered > thead > tr > td:first-child,
.panel > .table-responsive > .table-bordered > thead > tr > td:first-child,
.panel > .table-bordered > tbody > tr > td:first-child,
.panel > .table-responsive > .table-bordered > tbody > tr > td:first-child,
.panel > .table-bordered > tfoot > tr > td:first-child,
.panel > .table-responsive > .table-bordered > tfoot > tr > td:first-child {
  border-left: 0;
}
.panel > .table-bordered > thead > tr > th:last-child,
.panel > .table-responsive > .table-bordered > thead > tr > th:last-child,
.panel > .table-bordered > tbody > tr > th:last-child,
.panel > .table-responsive > .table-bordered > tbody > tr > th:last-child,
.panel > .table-bordered > tfoot > tr > th:last-child,
.panel > .table-responsive > .table-bordered > tfoot > tr > th:last-child,
.panel > .table-bordered > thead > tr > td:last-child,
.panel > .table-responsive > .table-bordered > thead > tr > td:last-child,
.panel > .table-bordered > tbody > tr > td:last-child,
.panel > .table-responsive > .table-bordered > tbody > tr > td:last-child,
.panel > .table-bordered > tfoot > tr > td:last-child,
.panel > .table-responsive > .table-bordered > tfoot > tr > td:last-child {
  border-right: 0;
}
.panel > .table-bordered > thead > tr:first-child > td,
.panel > .table-responsive > .table-bordered > thead > tr:first-child > td,
.panel > .table-bordered > tbody > tr:first-child > td,
.panel > .table-responsive > .table-bordered > tbody > tr:first-child > td,
.panel > .table-bordered > thead > tr:first-child > th,
.panel > .table-responsive > .table-bordered > thead > tr:first-child > th,
.panel > .table-bordered > tbody > tr:first-child > th,
.panel > .table-responsive > .table-bordered > tbody > tr:first-child > th {
  border-bottom: 0;
}
.panel > .table-bordered > tbody > tr:last-child > td,
.panel > .table-responsive > .table-bordered > tbody > tr:last-child > td,
.panel > .table-bordered > tfoot > tr:last-child > td,
.panel > .table-responsive > .table-bordered > tfoot > tr:last-child > td,
.panel > .table-bordered > tbody > tr:last-child > th,
.panel > .table-responsive > .table-bordered > tbody > tr:last-child > th,
.panel > .table-bordered > tfoot > tr:last-child > th,
.panel > .table-responsive > .table-bordered > tfoot > tr:last-child > th {
  border-bottom: 0;
}
.panel > .table-responsive {
  border: 0;
  margin-bottom: 0;
}
.panel-group {
  margin-bottom: 18px;
}
.panel-group .panel {
  margin-bottom: 0;
  border-radius: 2px;
}
.panel-group .panel + .panel {
  margin-top: 5px;
}
.panel-group .panel-heading {
  border-bottom: 0;
}
.panel-group .panel-heading + .panel-collapse > .panel-body,
.panel-group .panel-heading + .panel-collapse > .list-group {
  border-top: 1px solid #ddd;
}
.panel-group .panel-footer {
  border-top: 0;
}
.panel-group .panel-footer + .panel-collapse .panel-body {
  border-bottom: 1px solid #ddd;
}
.panel-default {
  border-color: #ddd;
}
.panel-default > .panel-heading {
  color: #333333;
  background-color: #f5f5f5;
  border-color: #ddd;
}
.panel-default > .panel-heading + .panel-collapse > .panel-body {
  border-top-color: #ddd;
}
.panel-default > .panel-heading .badge {
  color: #f5f5f5;
  background-color: #333333;
}
.panel-default > .panel-footer + .panel-collapse > .panel-body {
  border-bottom-color: #ddd;
}
.panel-primary {
  border-color: #337ab7;
}
.panel-primary > .panel-heading {
  color: #fff;
  background-color: #337ab7;
  border-color: #337ab7;
}
.panel-primary > .panel-heading + .panel-collapse > .panel-body {
  border-top-color: #337ab7;
}
.panel-primary > .panel-heading .badge {
  color: #337ab7;
  background-color: #fff;
}
.panel-primary > .panel-footer + .panel-collapse > .panel-body {
  border-bottom-color: #337ab7;
}
.panel-success {
  border-color: #d6e9c6;
}
.panel-success > .panel-heading {
  color: #3c763d;
  background-color: #dff0d8;
  border-color: #d6e9c6;
}
.panel-success > .panel-heading + .panel-collapse > .panel-body {
  border-top-color: #d6e9c6;
}
.panel-success > .panel-heading .badge {
  color: #dff0d8;
  background-color: #3c763d;
}
.panel-success > .panel-footer + .panel-collapse > .panel-body {
  border-bottom-color: #d6e9c6;
}
.panel-info {
  border-color: #bce8f1;
}
.panel-info > .panel-heading {
  color: #31708f;
  background-color: #d9edf7;
  border-color: #bce8f1;
}
.panel-info > .panel-heading + .panel-collapse > .panel-body {
  border-top-color: #bce8f1;
}
.panel-info > .panel-heading .badge {
  color: #d9edf7;
  background-color: #31708f;
}
.panel-info > .panel-footer + .panel-collapse > .panel-body {
  border-bottom-color: #bce8f1;
}
.panel-warning {
  border-color: #faebcc;
}
.panel-warning > .panel-heading {
  color: #8a6d3b;
  background-color: #fcf8e3;
  border-color: #faebcc;
}
.panel-warning > .panel-heading + .panel-collapse > .panel-body {
  border-top-color: #faebcc;
}
.panel-warning > .panel-heading .badge {
  color: #fcf8e3;
  background-color: #8a6d3b;
}
.panel-warning > .panel-footer + .panel-collapse > .panel-body {
  border-bottom-color: #faebcc;
}
.panel-danger {
  border-color: #ebccd1;
}
.panel-danger > .panel-heading {
  color: #a94442;
  background-color: #f2dede;
  border-color: #ebccd1;
}
.panel-danger > .panel-heading + .panel-collapse > .panel-body {
  border-top-color: #ebccd1;
}
.panel-danger > .panel-heading .badge {
  color: #f2dede;
  background-color: #a94442;
}
.panel-danger > .panel-footer + .panel-collapse > .panel-body {
  border-bottom-color: #ebccd1;
}
.embed-responsive {
  position: relative;
  display: block;
  height: 0;
  padding: 0;
  overflow: hidden;
}
.embed-responsive .embed-responsive-item,
.embed-responsive iframe,
.embed-responsive embed,
.embed-responsive object,
.embed-responsive video {
  position: absolute;
  top: 0;
  left: 0;
  bottom: 0;
  height: 100%;
  width: 100%;
  border: 0;
}
.embed-responsive-16by9 {
  padding-bottom: 56.25%;
}
.embed-responsive-4by3 {
  padding-bottom: 75%;
}
.well {
  min-height: 20px;
  padding: 19px;
  margin-bottom: 20px;
  background-color: #f5f5f5;
  border: 1px solid #e3e3e3;
  border-radius: 2px;
  -webkit-box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.05);
  box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.05);
}
.well blockquote {
  border-color: #ddd;
  border-color: rgba(0, 0, 0, 0.15);
}
.well-lg {
  padding: 24px;
  border-radius: 3px;
}
.well-sm {
  padding: 9px;
  border-radius: 1px;
}
.close {
  float: right;
  font-size: 19.5px;
  font-weight: bold;
  line-height: 1;
  color: #000;
  text-shadow: 0 1px 0 #fff;
  opacity: 0.2;
  filter: alpha(opacity=20);
}
.close:hover,
.close:focus {
  color: #000;
  text-decoration: none;
  cursor: pointer;
  opacity: 0.5;
  filter: alpha(opacity=50);
}
button.close {
  padding: 0;
  cursor: pointer;
  background: transparent;
  border: 0;
  -webkit-appearance: none;
}
.modal-open {
  overflow: hidden;
}
.modal {
  display: none;
  overflow: hidden;
  position: fixed;
  top: 0;
  right: 0;
  bottom: 0;
  left: 0;
  z-index: 1050;
  -webkit-overflow-scrolling: touch;
  outline: 0;
}
.modal.fade .modal-dialog {
  -webkit-transform: translate(0, -25%);
  -ms-transform: translate(0, -25%);
  -o-transform: translate(0, -25%);
  transform: translate(0, -25%);
  -webkit-transition: -webkit-transform 0.3s ease-out;
  -moz-transition: -moz-transform 0.3s ease-out;
  -o-transition: -o-transform 0.3s ease-out;
  transition: transform 0.3s ease-out;
}
.modal.in .modal-dialog {
  -webkit-transform: translate(0, 0);
  -ms-transform: translate(0, 0);
  -o-transform: translate(0, 0);
  transform: translate(0, 0);
}
.modal-open .modal {
  overflow-x: hidden;
  overflow-y: auto;
}
.modal-dialog {
  position: relative;
  width: auto;
  margin: 10px;
}
.modal-content {
  position: relative;
  background-color: #fff;
  border: 1px solid #999;
  border: 1px solid rgba(0, 0, 0, 0.2);
  border-radius: 3px;
  -webkit-box-shadow: 0 3px 9px rgba(0, 0, 0, 0.5);
  box-shadow: 0 3px 9px rgba(0, 0, 0, 0.5);
  background-clip: padding-box;
  outline: 0;
}
.modal-backdrop {
  position: fixed;
  top: 0;
  right: 0;
  bottom: 0;
  left: 0;
  z-index: 1040;
  background-color: #000;
}
.modal-backdrop.fade {
  opacity: 0;
  filter: alpha(opacity=0);
}
.modal-backdrop.in {
  opacity: 0.5;
  filter: alpha(opacity=50);
}
.modal-header {
  padding: 15px;
  border-bottom: 1px solid #e5e5e5;
}
.modal-header .close {
  margin-top: -2px;
}
.modal-title {
  margin: 0;
  line-height: 1.42857143;
}
.modal-body {
  position: relative;
  padding: 15px;
}
.modal-footer {
  padding: 15px;
  text-align: right;
  border-top: 1px solid #e5e5e5;
}
.modal-footer .btn + .btn {
  margin-left: 5px;
  margin-bottom: 0;
}
.modal-footer .btn-group .btn + .btn {
  margin-left: -1px;
}
.modal-footer .btn-block + .btn-block {
  margin-left: 0;
}
.modal-scrollbar-measure {
  position: absolute;
  top: -9999px;
  width: 50px;
  height: 50px;
  overflow: scroll;
}
@media (min-width: 768px) {
  .modal-dialog {
    width: 600px;
    margin: 30px auto;
  }
  .modal-content {
    -webkit-box-shadow: 0 5px 15px rgba(0, 0, 0, 0.5);
    box-shadow: 0 5px 15px rgba(0, 0, 0, 0.5);
  }
  .modal-sm {
    width: 300px;
  }
}
@media (min-width: 992px) {
  .modal-lg {
    width: 900px;
  }
}
.tooltip {
  position: absolute;
  z-index: 1070;
  display: block;
  font-family: "Helvetica Neue", Helvetica, Arial, sans-serif;
  font-style: normal;
  font-weight: normal;
  letter-spacing: normal;
  line-break: auto;
  line-height: 1.42857143;
  text-align: left;
  text-align: start;
  text-decoration: none;
  text-shadow: none;
  text-transform: none;
  white-space: normal;
  word-break: normal;
  word-spacing: normal;
  word-wrap: normal;
  font-size: 12px;
  opacity: 0;
  filter: alpha(opacity=0);
}
.tooltip.in {
  opacity: 0.9;
  filter: alpha(opacity=90);
}
.tooltip.top {
  margin-top: -3px;
  padding: 5px 0;
}
.tooltip.right {
  margin-left: 3px;
  padding: 0 5px;
}
.tooltip.bottom {
  margin-top: 3px;
  padding: 5px 0;
}
.tooltip.left {
  margin-left: -3px;
  padding: 0 5px;
}
.tooltip-inner {
  max-width: 200px;
  padding: 3px 8px;
  color: #fff;
  text-align: center;
  background-color: #000;
  border-radius: 2px;
}
.tooltip-arrow {
  position: absolute;
  width: 0;
  height: 0;
  border-color: transparent;
  border-style: solid;
}
.tooltip.top .tooltip-arrow {
  bottom: 0;
  left: 50%;
  margin-left: -5px;
  border-width: 5px 5px 0;
  border-top-color: #000;
}
.tooltip.top-left .tooltip-arrow {
  bottom: 0;
  right: 5px;
  margin-bottom: -5px;
  border-width: 5px 5px 0;
  border-top-color: #000;
}
.tooltip.top-right .tooltip-arrow {
  bottom: 0;
  left: 5px;
  margin-bottom: -5px;
  border-width: 5px 5px 0;
  border-top-color: #000;
}
.tooltip.right .tooltip-arrow {
  top: 50%;
  left: 0;
  margin-top: -5px;
  border-width: 5px 5px 5px 0;
  border-right-color: #000;
}
.tooltip.left .tooltip-arrow {
  top: 50%;
  right: 0;
  margin-top: -5px;
  border-width: 5px 0 5px 5px;
  border-left-color: #000;
}
.tooltip.bottom .tooltip-arrow {
  top: 0;
  left: 50%;
  margin-left: -5px;
  border-width: 0 5px 5px;
  border-bottom-color: #000;
}
.tooltip.bottom-left .tooltip-arrow {
  top: 0;
  right: 5px;
  margin-top: -5px;
  border-width: 0 5px 5px;
  border-bottom-color: #000;
}
.tooltip.bottom-right .tooltip-arrow {
  top: 0;
  left: 5px;
  margin-top: -5px;
  border-width: 0 5px 5px;
  border-bottom-color: #000;
}
.popover {
  position: absolute;
  top: 0;
  left: 0;
  z-index: 1060;
  display: none;
  max-width: 276px;
  padding: 1px;
  font-family: "Helvetica Neue", Helvetica, Arial, sans-serif;
  font-style: normal;
  font-weight: normal;
  letter-spacing: normal;
  line-break: auto;
  line-height: 1.42857143;
  text-align: left;
  text-align: start;
  text-decoration: none;
  text-shadow: none;
  text-transform: none;
  white-space: normal;
  word-break: normal;
  word-spacing: normal;
  word-wrap: normal;
  font-size: 13px;
  background-color: #fff;
  background-clip: padding-box;
  border: 1px solid #ccc;
  border: 1px solid rgba(0, 0, 0, 0.2);
  border-radius: 3px;
  -webkit-box-shadow: 0 5px 10px rgba(0, 0, 0, 0.2);
  box-shadow: 0 5px 10px rgba(0, 0, 0, 0.2);
}
.popover.top {
  margin-top: -10px;
}
.popover.right {
  margin-left: 10px;
}
.popover.bottom {
  margin-top: 10px;
}
.popover.left {
  margin-left: -10px;
}
.popover-title {
  margin: 0;
  padding: 8px 14px;
  font-size: 13px;
  background-color: #f7f7f7;
  border-bottom: 1px solid #ebebeb;
  border-radius: 2px 2px 0 0;
}
.popover-content {
  padding: 9px 14px;
}
.popover > .arrow,
.popover > .arrow:after {
  position: absolute;
  display: block;
  width: 0;
  height: 0;
  border-color: transparent;
  border-style: solid;
}
.popover > .arrow {
  border-width: 11px;
}
.popover > .arrow:after {
  border-width: 10px;
  content: "";
}
.popover.top > .arrow {
  left: 50%;
  margin-left: -11px;
  border-bottom-width: 0;
  border-top-color: #999999;
  border-top-color: rgba(0, 0, 0, 0.25);
  bottom: -11px;
}
.popover.top > .arrow:after {
  content: " ";
  bottom: 1px;
  margin-left: -10px;
  border-bottom-width: 0;
  border-top-color: #fff;
}
.popover.right > .arrow {
  top: 50%;
  left: -11px;
  margin-top: -11px;
  border-left-width: 0;
  border-right-color: #999999;
  border-right-color: rgba(0, 0, 0, 0.25);
}
.popover.right > .arrow:after {
  content: " ";
  left: 1px;
  bottom: -10px;
  border-left-width: 0;
  border-right-color: #fff;
}
.popover.bottom > .arrow {
  left: 50%;
  margin-left: -11px;
  border-top-width: 0;
  border-bottom-color: #999999;
  border-bottom-color: rgba(0, 0, 0, 0.25);
  top: -11px;
}
.popover.bottom > .arrow:after {
  content: " ";
  top: 1px;
  margin-left: -10px;
  border-top-width: 0;
  border-bottom-color: #fff;
}
.popover.left > .arrow {
  top: 50%;
  right: -11px;
  margin-top: -11px;
  border-right-width: 0;
  border-left-color: #999999;
  border-left-color: rgba(0, 0, 0, 0.25);
}
.popover.left > .arrow:after {
  content: " ";
  right: 1px;
  border-right-width: 0;
  border-left-color: #fff;
  bottom: -10px;
}
.carousel {
  position: relative;
}
.carousel-inner {
  position: relative;
  overflow: hidden;
  width: 100%;
}
.carousel-inner > .item {
  display: none;
  position: relative;
  -webkit-transition: 0.6s ease-in-out left;
  -o-transition: 0.6s ease-in-out left;
  transition: 0.6s ease-in-out left;
}
.carousel-inner > .item > img,
.carousel-inner > .item > a > img {
  line-height: 1;
}
@media all and (transform-3d), (-webkit-transform-3d) {
  .carousel-inner > .item {
    -webkit-transition: -webkit-transform 0.6s ease-in-out;
    -moz-transition: -moz-transform 0.6s ease-in-out;
    -o-transition: -o-transform 0.6s ease-in-out;
    transition: transform 0.6s ease-in-out;
    -webkit-backface-visibility: hidden;
    -moz-backface-visibility: hidden;
    backface-visibility: hidden;
    -webkit-perspective: 1000px;
    -moz-perspective: 1000px;
    perspective: 1000px;
  }
  .carousel-inner > .item.next,
  .carousel-inner > .item.active.right {
    -webkit-transform: translate3d(100%, 0, 0);
    transform: translate3d(100%, 0, 0);
    left: 0;
  }
  .carousel-inner > .item.prev,
  .carousel-inner > .item.active.left {
    -webkit-transform: translate3d(-100%, 0, 0);
    transform: translate3d(-100%, 0, 0);
    left: 0;
  }
  .carousel-inner > .item.next.left,
  .carousel-inner > .item.prev.right,
  .carousel-inner > .item.active {
    -webkit-transform: translate3d(0, 0, 0);
    transform: translate3d(0, 0, 0);
    left: 0;
  }
}
.carousel-inner > .active,
.carousel-inner > .next,
.carousel-inner > .prev {
  display: block;
}
.carousel-inner > .active {
  left: 0;
}
.carousel-inner > .next,
.carousel-inner > .prev {
  position: absolute;
  top: 0;
  width: 100%;
}
.carousel-inner > .next {
  left: 100%;
}
.carousel-inner > .prev {
  left: -100%;
}
.carousel-inner > .next.left,
.carousel-inner > .prev.right {
  left: 0;
}
.carousel-inner > .active.left {
  left: -100%;
}
.carousel-inner > .active.right {
  left: 100%;
}
.carousel-control {
  position: absolute;
  top: 0;
  left: 0;
  bottom: 0;
  width: 15%;
  opacity: 0.5;
  filter: alpha(opacity=50);
  font-size: 20px;
  color: #fff;
  text-align: center;
  text-shadow: 0 1px 2px rgba(0, 0, 0, 0.6);
  background-color: rgba(0, 0, 0, 0);
}
.carousel-control.left {
  background-image: -webkit-linear-gradient(left, rgba(0, 0, 0, 0.5) 0%, rgba(0, 0, 0, 0.0001) 100%);
  background-image: -o-linear-gradient(left, rgba(0, 0, 0, 0.5) 0%, rgba(0, 0, 0, 0.0001) 100%);
  background-image: linear-gradient(to right, rgba(0, 0, 0, 0.5) 0%, rgba(0, 0, 0, 0.0001) 100%);
  background-repeat: repeat-x;
  filter: progid:DXImageTransform.Microsoft.gradient(startColorstr='#80000000', endColorstr='#00000000', GradientType=1);
}
.carousel-control.right {
  left: auto;
  right: 0;
  background-image: -webkit-linear-gradient(left, rgba(0, 0, 0, 0.0001) 0%, rgba(0, 0, 0, 0.5) 100%);
  background-image: -o-linear-gradient(left, rgba(0, 0, 0, 0.0001) 0%, rgba(0, 0, 0, 0.5) 100%);
  background-image: linear-gradient(to right, rgba(0, 0, 0, 0.0001) 0%, rgba(0, 0, 0, 0.5) 100%);
  background-repeat: repeat-x;
  filter: progid:DXImageTransform.Microsoft.gradient(startColorstr='#00000000', endColorstr='#80000000', GradientType=1);
}
.carousel-control:hover,
.carousel-control:focus {
  outline: 0;
  color: #fff;
  text-decoration: none;
  opacity: 0.9;
  filter: alpha(opacity=90);
}
.carousel-control .icon-prev,
.carousel-control .icon-next,
.carousel-control .glyphicon-chevron-left,
.carousel-control .glyphicon-chevron-right {
  position: absolute;
  top: 50%;
  margin-top: -10px;
  z-index: 5;
  display: inline-block;
}
.carousel-control .icon-prev,
.carousel-control .glyphicon-chevron-left {
  left: 50%;
  margin-left: -10px;
}
.carousel-control .icon-next,
.carousel-control .glyphicon-chevron-right {
  right: 50%;
  margin-right: -10px;
}
.carousel-control .icon-prev,
.carousel-control .icon-next {
  width: 20px;
  height: 20px;
  line-height: 1;
  font-family: serif;
}
.carousel-control .icon-prev:before {
  content: '\2039';
}
.carousel-control .icon-next:before {
  content: '\203a';
}
.carousel-indicators {
  position: absolute;
  bottom: 10px;
  left: 50%;
  z-index: 15;
  width: 60%;
  margin-left: -30%;
  padding-left: 0;
  list-style: none;
  text-align: center;
}
.carousel-indicators li {
  display: inline-block;
  width: 10px;
  height: 10px;
  margin: 1px;
  text-indent: -999px;
  border: 1px solid #fff;
  border-radius: 10px;
  cursor: pointer;
  background-color: #000 \9;
  background-color: rgba(0, 0, 0, 0);
}
.carousel-indicators .active {
  margin: 0;
  width: 12px;
  height: 12px;
  background-color: #fff;
}
.carousel-caption {
  position: absolute;
  left: 15%;
  right: 15%;
  bottom: 20px;
  z-index: 10;
  padding-top: 20px;
  padding-bottom: 20px;
  color: #fff;
  text-align: center;
  text-shadow: 0 1px 2px rgba(0, 0, 0, 0.6);
}
.carousel-caption .btn {
  text-shadow: none;
}
@media screen and (min-width: 768px) {
  .carousel-control .glyphicon-chevron-left,
  .carousel-control .glyphicon-chevron-right,
  .carousel-control .icon-prev,
  .carousel-control .icon-next {
    width: 30px;
    height: 30px;
    margin-top: -10px;
    font-size: 30px;
  }
  .carousel-control .glyphicon-chevron-left,
  .carousel-control .icon-prev {
    margin-left: -10px;
  }
  .carousel-control .glyphicon-chevron-right,
  .carousel-control .icon-next {
    margin-right: -10px;
  }
  .carousel-caption {
    left: 20%;
    right: 20%;
    padding-bottom: 30px;
  }
  .carousel-indicators {
    bottom: 20px;
  }
}
.clearfix:before,
.clearfix:after,
.dl-horizontal dd:before,
.dl-horizontal dd:after,
.container:before,
.container:after,
.container-fluid:before,
.container-fluid:after,
.row:before,
.row:after,
.form-horizontal .form-group:before,
.form-horizontal .form-group:after,
.btn-toolbar:before,
.btn-toolbar:after,
.btn-group-vertical > .btn-group:before,
.btn-group-vertical > .btn-group:after,
.nav:before,
.nav:after,
.navbar:before,
.navbar:after,
.navbar-header:before,
.navbar-header:after,
.navbar-collapse:before,
.navbar-collapse:after,
.pager:before,
.pager:after,
.panel-body:before,
.panel-body:after,
.modal-header:before,
.modal-header:after,
.modal-footer:before,
.modal-footer:after,
.item_buttons:before,
.item_buttons:after {
  content: " ";
  display: table;
}
.clearfix:after,
.dl-horizontal dd:after,
.container:after,
.container-fluid:after,
.row:after,
.form-horizontal .form-group:after,
.btn-toolbar:after,
.btn-group-vertical > .btn-group:after,
.nav:after,
.navbar:after,
.navbar-header:after,
.navbar-collapse:after,
.pager:after,
.panel-body:after,
.modal-header:after,
.modal-footer:after,
.item_buttons:after {
  clear: both;
}
.center-block {
  display: block;
  margin-left: auto;
  margin-right: auto;
}
.pull-right {
  float: right !important;
}
.pull-left {
  float: left !important;
}
.hide {
  display: none !important;
}
.show {
  display: block !important;
}
.invisible {
  visibility: hidden;
}
.text-hide {
  font: 0/0 a;
  color: transparent;
  text-shadow: none;
  background-color: transparent;
  border: 0;
}
.hidden {
  display: none !important;
}
.affix {
  position: fixed;
}
@-ms-viewport {
  width: device-width;
}
.visible-xs,
.visible-sm,
.visible-md,
.visible-lg {
  display: none !important;
}
.visible-xs-block,
.visible-xs-inline,
.visible-xs-inline-block,
.visible-sm-block,
.visible-sm-inline,
.visible-sm-inline-block,
.visible-md-block,
.visible-md-inline,
.visible-md-inline-block,
.visible-lg-block,
.visible-lg-inline,
.visible-lg-inline-block {
  display: none !important;
}
@media (max-width: 767px) {
  .visible-xs {
    display: block !important;
  }
  table.visible-xs {
    display: table !important;
  }
  tr.visible-xs {
    display: table-row !important;
  }
  th.visible-xs,
  td.visible-xs {
    display: table-cell !important;
  }
}
@media (max-width: 767px) {
  .visible-xs-block {
    display: block !important;
  }
}
@media (max-width: 767px) {
  .visible-xs-inline {
    display: inline !important;
  }
}
@media (max-width: 767px) {
  .visible-xs-inline-block {
    display: inline-block !important;
  }
}
@media (min-width: 768px) and (max-width: 991px) {
  .visible-sm {
    display: block !important;
  }
  table.visible-sm {
    display: table !important;
  }
  tr.visible-sm {
    display: table-row !important;
  }
  th.visible-sm,
  td.visible-sm {
    display: table-cell !important;
  }
}
@media (min-width: 768px) and (max-width: 991px) {
  .visible-sm-block {
    display: block !important;
  }
}
@media (min-width: 768px) and (max-width: 991px) {
  .visible-sm-inline {
    display: inline !important;
  }
}
@media (min-width: 768px) and (max-width: 991px) {
  .visible-sm-inline-block {
    display: inline-block !important;
  }
}
@media (min-width: 992px) and (max-width: 1199px) {
  .visible-md {
    display: block !important;
  }
  table.visible-md {
    display: table !important;
  }
  tr.visible-md {
    display: table-row !important;
  }
  th.visible-md,
  td.visible-md {
    display: table-cell !important;
  }
}
@media (min-width: 992px) and (max-width: 1199px) {
  .visible-md-block {
    display: block !important;
  }
}
@media (min-width: 992px) and (max-width: 1199px) {
  .visible-md-inline {
    display: inline !important;
  }
}
@media (min-width: 992px) and (max-width: 1199px) {
  .visible-md-inline-block {
    display: inline-block !important;
  }
}
@media (min-width: 1200px) {
  .visible-lg {
    display: block !important;
  }
  table.visible-lg {
    display: table !important;
  }
  tr.visible-lg {
    display: table-row !important;
  }
  th.visible-lg,
  td.visible-lg {
    display: table-cell !important;
  }
}
@media (min-width: 1200px) {
  .visible-lg-block {
    display: block !important;
  }
}
@media (min-width: 1200px) {
  .visible-lg-inline {
    display: inline !important;
  }
}
@media (min-width: 1200px) {
  .visible-lg-inline-block {
    display: inline-block !important;
  }
}
@media (max-width: 767px) {
  .hidden-xs {
    display: none !important;
  }
}
@media (min-width: 768px) and (max-width: 991px) {
  .hidden-sm {
    display: none !important;
  }
}
@media (min-width: 992px) and (max-width: 1199px) {
  .hidden-md {
    display: none !important;
  }
}
@media (min-width: 1200px) {
  .hidden-lg {
    display: none !important;
  }
}
.visible-print {
  display: none !important;
}
@media print {
  .visible-print {
    display: block !important;
  }
  table.visible-print {
    display: table !important;
  }
  tr.visible-print {
    display: table-row !important;
  }
  th.visible-print,
  td.visible-print {
    display: table-cell !important;
  }
}
.visible-print-block {
  display: none !important;
}
@media print {
  .visible-print-block {
    display: block !important;
  }
}
.visible-print-inline {
  display: none !important;
}
@media print {
  .visible-print-inline {
    display: inline !important;
  }
}
.visible-print-inline-block {
  display: none !important;
}
@media print {
  .visible-print-inline-block {
    display: inline-block !important;
  }
}
@media print {
  .hidden-print {
    display: none !important;
  }
}
/*!
*
* Font Awesome
*
*/
/*!
 *  Font Awesome 4.2.0 by @davegandy - http://fontawesome.io - @fontawesome
 *  License - http://fontawesome.io/license (Font: SIL OFL 1.1, CSS: MIT License)
 */
/* FONT PATH
 * -------------------------- */
@font-face {
  font-family: 'FontAwesome';
  src: url('../components/font-awesome/fonts/fontawesome-webfont.eot?v=4.2.0');
  src: url('../components/font-awesome/fonts/fontawesome-webfont.eot?#iefix&v=4.2.0') format('embedded-opentype'), url('../components/font-awesome/fonts/fontawesome-webfont.woff?v=4.2.0') format('woff'), url('../components/font-awesome/fonts/fontawesome-webfont.ttf?v=4.2.0') format('truetype'), url('../components/font-awesome/fonts/fontawesome-webfont.svg?v=4.2.0#fontawesomeregular') format('svg');
  font-weight: normal;
  font-style: normal;
}
.fa {
  display: inline-block;
  font: normal normal normal 14px/1 FontAwesome;
  font-size: inherit;
  text-rendering: auto;
  -webkit-font-smoothing: antialiased;
  -moz-osx-font-smoothing: grayscale;
}
/* makes the font 33% larger relative to the icon container */
.fa-lg {
  font-size: 1.33333333em;
  line-height: 0.75em;
  vertical-align: -15%;
}
.fa-2x {
  font-size: 2em;
}
.fa-3x {
  font-size: 3em;
}
.fa-4x {
  font-size: 4em;
}
.fa-5x {
  font-size: 5em;
}
.fa-fw {
  width: 1.28571429em;
  text-align: center;
}
.fa-ul {
  padding-left: 0;
  margin-left: 2.14285714em;
  list-style-type: none;
}
.fa-ul > li {
  position: relative;
}
.fa-li {
  position: absolute;
  left: -2.14285714em;
  width: 2.14285714em;
  top: 0.14285714em;
  text-align: center;
}
.fa-li.fa-lg {
  left: -1.85714286em;
}
.fa-border {
  padding: .2em .25em .15em;
  border: solid 0.08em #eee;
  border-radius: .1em;
}
.pull-right {
  float: right;
}
.pull-left {
  float: left;
}
.fa.pull-left {
  margin-right: .3em;
}
.fa.pull-right {
  margin-left: .3em;
}
.fa-spin {
  -webkit-animation: fa-spin 2s infinite linear;
  animation: fa-spin 2s infinite linear;
}
@-webkit-keyframes fa-spin {
  0% {
    -webkit-transform: rotate(0deg);
    transform: rotate(0deg);
  }
  100% {
    -webkit-transform: rotate(359deg);
    transform: rotate(359deg);
  }
}
@keyframes fa-spin {
  0% {
    -webkit-transform: rotate(0deg);
    transform: rotate(0deg);
  }
  100% {
    -webkit-transform: rotate(359deg);
    transform: rotate(359deg);
  }
}
.fa-rotate-90 {
  filter: progid:DXImageTransform.Microsoft.BasicImage(rotation=1);
  -webkit-transform: rotate(90deg);
  -ms-transform: rotate(90deg);
  transform: rotate(90deg);
}
.fa-rotate-180 {
  filter: progid:DXImageTransform.Microsoft.BasicImage(rotation=2);
  -webkit-transform: rotate(180deg);
  -ms-transform: rotate(180deg);
  transform: rotate(180deg);
}
.fa-rotate-270 {
  filter: progid:DXImageTransform.Microsoft.BasicImage(rotation=3);
  -webkit-transform: rotate(270deg);
  -ms-transform: rotate(270deg);
  transform: rotate(270deg);
}
.fa-flip-horizontal {
  filter: progid:DXImageTransform.Microsoft.BasicImage(rotation=0, mirror=1);
  -webkit-transform: scale(-1, 1);
  -ms-transform: scale(-1, 1);
  transform: scale(-1, 1);
}
.fa-flip-vertical {
  filter: progid:DXImageTransform.Microsoft.BasicImage(rotation=2, mirror=1);
  -webkit-transform: scale(1, -1);
  -ms-transform: scale(1, -1);
  transform: scale(1, -1);
}
:root .fa-rotate-90,
:root .fa-rotate-180,
:root .fa-rotate-270,
:root .fa-flip-horizontal,
:root .fa-flip-vertical {
  filter: none;
}
.fa-stack {
  position: relative;
  display: inline-block;
  width: 2em;
  height: 2em;
  line-height: 2em;
  vertical-align: middle;
}
.fa-stack-1x,
.fa-stack-2x {
  position: absolute;
  left: 0;
  width: 100%;
  text-align: center;
}
.fa-stack-1x {
  line-height: inherit;
}
.fa-stack-2x {
  font-size: 2em;
}
.fa-inverse {
  color: #fff;
}
/* Font Awesome uses the Unicode Private Use Area (PUA) to ensure screen
   readers do not read off random characters that represent icons */
.fa-glass:before {
  content: "\f000";
}
.fa-music:before {
  content: "\f001";
}
.fa-search:before {
  content: "\f002";
}
.fa-envelope-o:before {
  content: "\f003";
}
.fa-heart:before {
  content: "\f004";
}
.fa-star:before {
  content: "\f005";
}
.fa-star-o:before {
  content: "\f006";
}
.fa-user:before {
  content: "\f007";
}
.fa-film:before {
  content: "\f008";
}
.fa-th-large:before {
  content: "\f009";
}
.fa-th:before {
  content: "\f00a";
}
.fa-th-list:before {
  content: "\f00b";
}
.fa-check:before {
  content: "\f00c";
}
.fa-remove:before,
.fa-close:before,
.fa-times:before {
  content: "\f00d";
}
.fa-search-plus:before {
  content: "\f00e";
}
.fa-search-minus:before {
  content: "\f010";
}
.fa-power-off:before {
  content: "\f011";
}
.fa-signal:before {
  content: "\f012";
}
.fa-gear:before,
.fa-cog:before {
  content: "\f013";
}
.fa-trash-o:before {
  content: "\f014";
}
.fa-home:before {
  content: "\f015";
}
.fa-file-o:before {
  content: "\f016";
}
.fa-clock-o:before {
  content: "\f017";
}
.fa-road:before {
  content: "\f018";
}
.fa-download:before {
  content: "\f019";
}
.fa-arrow-circle-o-down:before {
  content: "\f01a";
}
.fa-arrow-circle-o-up:before {
  content: "\f01b";
}
.fa-inbox:before {
  content: "\f01c";
}
.fa-play-circle-o:before {
  content: "\f01d";
}
.fa-rotate-right:before,
.fa-repeat:before {
  content: "\f01e";
}
.fa-refresh:before {
  content: "\f021";
}
.fa-list-alt:before {
  content: "\f022";
}
.fa-lock:before {
  content: "\f023";
}
.fa-flag:before {
  content: "\f024";
}
.fa-headphones:before {
  content: "\f025";
}
.fa-volume-off:before {
  content: "\f026";
}
.fa-volume-down:before {
  content: "\f027";
}
.fa-volume-up:before {
  content: "\f028";
}
.fa-qrcode:before {
  content: "\f029";
}
.fa-barcode:before {
  content: "\f02a";
}
.fa-tag:before {
  content: "\f02b";
}
.fa-tags:before {
  content: "\f02c";
}
.fa-book:before {
  content: "\f02d";
}
.fa-bookmark:before {
  content: "\f02e";
}
.fa-print:before {
  content: "\f02f";
}
.fa-camera:before {
  content: "\f030";
}
.fa-font:before {
  content: "\f031";
}
.fa-bold:before {
  content: "\f032";
}
.fa-italic:before {
  content: "\f033";
}
.fa-text-height:before {
  content: "\f034";
}
.fa-text-width:before {
  content: "\f035";
}
.fa-align-left:before {
  content: "\f036";
}
.fa-align-center:before {
  content: "\f037";
}
.fa-align-right:before {
  content: "\f038";
}
.fa-align-justify:before {
  content: "\f039";
}
.fa-list:before {
  content: "\f03a";
}
.fa-dedent:before,
.fa-outdent:before {
  content: "\f03b";
}
.fa-indent:before {
  content: "\f03c";
}
.fa-video-camera:before {
  content: "\f03d";
}
.fa-photo:before,
.fa-image:before,
.fa-picture-o:before {
  content: "\f03e";
}
.fa-pencil:before {
  content: "\f040";
}
.fa-map-marker:before {
  content: "\f041";
}
.fa-adjust:before {
  content: "\f042";
}
.fa-tint:before {
  content: "\f043";
}
.fa-edit:before,
.fa-pencil-square-o:before {
  content: "\f044";
}
.fa-share-square-o:before {
  content: "\f045";
}
.fa-check-square-o:before {
  content: "\f046";
}
.fa-arrows:before {
  content: "\f047";
}
.fa-step-backward:before {
  content: "\f048";
}
.fa-fast-backward:before {
  content: "\f049";
}
.fa-backward:before {
  content: "\f04a";
}
.fa-play:before {
  content: "\f04b";
}
.fa-pause:before {
  content: "\f04c";
}
.fa-stop:before {
  content: "\f04d";
}
.fa-forward:before {
  content: "\f04e";
}
.fa-fast-forward:before {
  content: "\f050";
}
.fa-step-forward:before {
  content: "\f051";
}
.fa-eject:before {
  content: "\f052";
}
.fa-chevron-left:before {
  content: "\f053";
}
.fa-chevron-right:before {
  content: "\f054";
}
.fa-plus-circle:before {
  content: "\f055";
}
.fa-minus-circle:before {
  content: "\f056";
}
.fa-times-circle:before {
  content: "\f057";
}
.fa-check-circle:before {
  content: "\f058";
}
.fa-question-circle:before {
  content: "\f059";
}
.fa-info-circle:before {
  content: "\f05a";
}
.fa-crosshairs:before {
  content: "\f05b";
}
.fa-times-circle-o:before {
  content: "\f05c";
}
.fa-check-circle-o:before {
  content: "\f05d";
}
.fa-ban:before {
  content: "\f05e";
}
.fa-arrow-left:before {
  content: "\f060";
}
.fa-arrow-right:before {
  content: "\f061";
}
.fa-arrow-up:before {
  content: "\f062";
}
.fa-arrow-down:before {
  content: "\f063";
}
.fa-mail-forward:before,
.fa-share:before {
  content: "\f064";
}
.fa-expand:before {
  content: "\f065";
}
.fa-compress:before {
  content: "\f066";
}
.fa-plus:before {
  content: "\f067";
}
.fa-minus:before {
  content: "\f068";
}
.fa-asterisk:before {
  content: "\f069";
}
.fa-exclamation-circle:before {
  content: "\f06a";
}
.fa-gift:before {
  content: "\f06b";
}
.fa-leaf:before {
  content: "\f06c";
}
.fa-fire:before {
  content: "\f06d";
}
.fa-eye:before {
  content: "\f06e";
}
.fa-eye-slash:before {
  content: "\f070";
}
.fa-warning:before,
.fa-exclamation-triangle:before {
  content: "\f071";
}
.fa-plane:before {
  content: "\f072";
}
.fa-calendar:before {
  content: "\f073";
}
.fa-random:before {
  content: "\f074";
}
.fa-comment:before {
  content: "\f075";
}
.fa-magnet:before {
  content: "\f076";
}
.fa-chevron-up:before {
  content: "\f077";
}
.fa-chevron-down:before {
  content: "\f078";
}
.fa-retweet:before {
  content: "\f079";
}
.fa-shopping-cart:before {
  content: "\f07a";
}
.fa-folder:before {
  content: "\f07b";
}
.fa-folder-open:before {
  content: "\f07c";
}
.fa-arrows-v:before {
  content: "\f07d";
}
.fa-arrows-h:before {
  content: "\f07e";
}
.fa-bar-chart-o:before,
.fa-bar-chart:before {
  content: "\f080";
}
.fa-twitter-square:before {
  content: "\f081";
}
.fa-facebook-square:before {
  content: "\f082";
}
.fa-camera-retro:before {
  content: "\f083";
}
.fa-key:before {
  content: "\f084";
}
.fa-gears:before,
.fa-cogs:before {
  content: "\f085";
}
.fa-comments:before {
  content: "\f086";
}
.fa-thumbs-o-up:before {
  content: "\f087";
}
.fa-thumbs-o-down:before {
  content: "\f088";
}
.fa-star-half:before {
  content: "\f089";
}
.fa-heart-o:before {
  content: "\f08a";
}
.fa-sign-out:before {
  content: "\f08b";
}
.fa-linkedin-square:before {
  content: "\f08c";
}
.fa-thumb-tack:before {
  content: "\f08d";
}
.fa-external-link:before {
  content: "\f08e";
}
.fa-sign-in:before {
  content: "\f090";
}
.fa-trophy:before {
  content: "\f091";
}
.fa-github-square:before {
  content: "\f092";
}
.fa-upload:before {
  content: "\f093";
}
.fa-lemon-o:before {
  content: "\f094";
}
.fa-phone:before {
  content: "\f095";
}
.fa-square-o:before {
  content: "\f096";
}
.fa-bookmark-o:before {
  content: "\f097";
}
.fa-phone-square:before {
  content: "\f098";
}
.fa-twitter:before {
  content: "\f099";
}
.fa-facebook:before {
  content: "\f09a";
}
.fa-github:before {
  content: "\f09b";
}
.fa-unlock:before {
  content: "\f09c";
}
.fa-credit-card:before {
  content: "\f09d";
}
.fa-rss:before {
  content: "\f09e";
}
.fa-hdd-o:before {
  content: "\f0a0";
}
.fa-bullhorn:before {
  content: "\f0a1";
}
.fa-bell:before {
  content: "\f0f3";
}
.fa-certificate:before {
  content: "\f0a3";
}
.fa-hand-o-right:before {
  content: "\f0a4";
}
.fa-hand-o-left:before {
  content: "\f0a5";
}
.fa-hand-o-up:before {
  content: "\f0a6";
}
.fa-hand-o-down:before {
  content: "\f0a7";
}
.fa-arrow-circle-left:before {
  content: "\f0a8";
}
.fa-arrow-circle-right:before {
  content: "\f0a9";
}
.fa-arrow-circle-up:before {
  content: "\f0aa";
}
.fa-arrow-circle-down:before {
  content: "\f0ab";
}
.fa-globe:before {
  content: "\f0ac";
}
.fa-wrench:before {
  content: "\f0ad";
}
.fa-tasks:before {
  content: "\f0ae";
}
.fa-filter:before {
  content: "\f0b0";
}
.fa-briefcase:before {
  content: "\f0b1";
}
.fa-arrows-alt:before {
  content: "\f0b2";
}
.fa-group:before,
.fa-users:before {
  content: "\f0c0";
}
.fa-chain:before,
.fa-link:before {
  content: "\f0c1";
}
.fa-cloud:before {
  content: "\f0c2";
}
.fa-flask:before {
  content: "\f0c3";
}
.fa-cut:before,
.fa-scissors:before {
  content: "\f0c4";
}
.fa-copy:before,
.fa-files-o:before {
  content: "\f0c5";
}
.fa-paperclip:before {
  content: "\f0c6";
}
.fa-save:before,
.fa-floppy-o:before {
  content: "\f0c7";
}
.fa-square:before {
  content: "\f0c8";
}
.fa-navicon:before,
.fa-reorder:before,
.fa-bars:before {
  content: "\f0c9";
}
.fa-list-ul:before {
  content: "\f0ca";
}
.fa-list-ol:before {
  content: "\f0cb";
}
.fa-strikethrough:before {
  content: "\f0cc";
}
.fa-underline:before {
  content: "\f0cd";
}
.fa-table:before {
  content: "\f0ce";
}
.fa-magic:before {
  content: "\f0d0";
}
.fa-truck:before {
  content: "\f0d1";
}
.fa-pinterest:before {
  content: "\f0d2";
}
.fa-pinterest-square:before {
  content: "\f0d3";
}
.fa-google-plus-square:before {
  content: "\f0d4";
}
.fa-google-plus:before {
  content: "\f0d5";
}
.fa-money:before {
  content: "\f0d6";
}
.fa-caret-down:before {
  content: "\f0d7";
}
.fa-caret-up:before {
  content: "\f0d8";
}
.fa-caret-left:before {
  content: "\f0d9";
}
.fa-caret-right:before {
  content: "\f0da";
}
.fa-columns:before {
  content: "\f0db";
}
.fa-unsorted:before,
.fa-sort:before {
  content: "\f0dc";
}
.fa-sort-down:before,
.fa-sort-desc:before {
  content: "\f0dd";
}
.fa-sort-up:before,
.fa-sort-asc:before {
  content: "\f0de";
}
.fa-envelope:before {
  content: "\f0e0";
}
.fa-linkedin:before {
  content: "\f0e1";
}
.fa-rotate-left:before,
.fa-undo:before {
  content: "\f0e2";
}
.fa-legal:before,
.fa-gavel:before {
  content: "\f0e3";
}
.fa-dashboard:before,
.fa-tachometer:before {
  content: "\f0e4";
}
.fa-comment-o:before {
  content: "\f0e5";
}
.fa-comments-o:before {
  content: "\f0e6";
}
.fa-flash:before,
.fa-bolt:before {
  content: "\f0e7";
}
.fa-sitemap:before {
  content: "\f0e8";
}
.fa-umbrella:before {
  content: "\f0e9";
}
.fa-paste:before,
.fa-clipboard:before {
  content: "\f0ea";
}
.fa-lightbulb-o:before {
  content: "\f0eb";
}
.fa-exchange:before {
  content: "\f0ec";
}
.fa-cloud-download:before {
  content: "\f0ed";
}
.fa-cloud-upload:before {
  content: "\f0ee";
}
.fa-user-md:before {
  content: "\f0f0";
}
.fa-stethoscope:before {
  content: "\f0f1";
}
.fa-suitcase:before {
  content: "\f0f2";
}
.fa-bell-o:before {
  content: "\f0a2";
}
.fa-coffee:before {
  content: "\f0f4";
}
.fa-cutlery:before {
  content: "\f0f5";
}
.fa-file-text-o:before {
  content: "\f0f6";
}
.fa-building-o:before {
  content: "\f0f7";
}
.fa-hospital-o:before {
  content: "\f0f8";
}
.fa-ambulance:before {
  content: "\f0f9";
}
.fa-medkit:before {
  content: "\f0fa";
}
.fa-fighter-jet:before {
  content: "\f0fb";
}
.fa-beer:before {
  content: "\f0fc";
}
.fa-h-square:before {
  content: "\f0fd";
}
.fa-plus-square:before {
  content: "\f0fe";
}
.fa-angle-double-left:before {
  content: "\f100";
}
.fa-angle-double-right:before {
  content: "\f101";
}
.fa-angle-double-up:before {
  content: "\f102";
}
.fa-angle-double-down:before {
  content: "\f103";
}
.fa-angle-left:before {
  content: "\f104";
}
.fa-angle-right:before {
  content: "\f105";
}
.fa-angle-up:before {
  content: "\f106";
}
.fa-angle-down:before {
  content: "\f107";
}
.fa-desktop:before {
  content: "\f108";
}
.fa-laptop:before {
  content: "\f109";
}
.fa-tablet:before {
  content: "\f10a";
}
.fa-mobile-phone:before,
.fa-mobile:before {
  content: "\f10b";
}
.fa-circle-o:before {
  content: "\f10c";
}
.fa-quote-left:before {
  content: "\f10d";
}
.fa-quote-right:before {
  content: "\f10e";
}
.fa-spinner:before {
  content: "\f110";
}
.fa-circle:before {
  content: "\f111";
}
.fa-mail-reply:before,
.fa-reply:before {
  content: "\f112";
}
.fa-github-alt:before {
  content: "\f113";
}
.fa-folder-o:before {
  content: "\f114";
}
.fa-folder-open-o:before {
  content: "\f115";
}
.fa-smile-o:before {
  content: "\f118";
}
.fa-frown-o:before {
  content: "\f119";
}
.fa-meh-o:before {
  content: "\f11a";
}
.fa-gamepad:before {
  content: "\f11b";
}
.fa-keyboard-o:before {
  content: "\f11c";
}
.fa-flag-o:before {
  content: "\f11d";
}
.fa-flag-checkered:before {
  content: "\f11e";
}
.fa-terminal:before {
  content: "\f120";
}
.fa-code:before {
  content: "\f121";
}
.fa-mail-reply-all:before,
.fa-reply-all:before {
  content: "\f122";
}
.fa-star-half-empty:before,
.fa-star-half-full:before,
.fa-star-half-o:before {
  content: "\f123";
}
.fa-location-arrow:before {
  content: "\f124";
}
.fa-crop:before {
  content: "\f125";
}
.fa-code-fork:before {
  content: "\f126";
}
.fa-unlink:before,
.fa-chain-broken:before {
  content: "\f127";
}
.fa-question:before {
  content: "\f128";
}
.fa-info:before {
  content: "\f129";
}
.fa-exclamation:before {
  content: "\f12a";
}
.fa-superscript:before {
  content: "\f12b";
}
.fa-subscript:before {
  content: "\f12c";
}
.fa-eraser:before {
  content: "\f12d";
}
.fa-puzzle-piece:before {
  content: "\f12e";
}
.fa-microphone:before {
  content: "\f130";
}
.fa-microphone-slash:before {
  content: "\f131";
}
.fa-shield:before {
  content: "\f132";
}
.fa-calendar-o:before {
  content: "\f133";
}
.fa-fire-extinguisher:before {
  content: "\f134";
}
.fa-rocket:before {
  content: "\f135";
}
.fa-maxcdn:before {
  content: "\f136";
}
.fa-chevron-circle-left:before {
  content: "\f137";
}
.fa-chevron-circle-right:before {
  content: "\f138";
}
.fa-chevron-circle-up:before {
  content: "\f139";
}
.fa-chevron-circle-down:before {
  content: "\f13a";
}
.fa-html5:before {
  content: "\f13b";
}
.fa-css3:before {
  content: "\f13c";
}
.fa-anchor:before {
  content: "\f13d";
}
.fa-unlock-alt:before {
  content: "\f13e";
}
.fa-bullseye:before {
  content: "\f140";
}
.fa-ellipsis-h:before {
  content: "\f141";
}
.fa-ellipsis-v:before {
  content: "\f142";
}
.fa-rss-square:before {
  content: "\f143";
}
.fa-play-circle:before {
  content: "\f144";
}
.fa-ticket:before {
  content: "\f145";
}
.fa-minus-square:before {
  content: "\f146";
}
.fa-minus-square-o:before {
  content: "\f147";
}
.fa-level-up:before {
  content: "\f148";
}
.fa-level-down:before {
  content: "\f149";
}
.fa-check-square:before {
  content: "\f14a";
}
.fa-pencil-square:before {
  content: "\f14b";
}
.fa-external-link-square:before {
  content: "\f14c";
}
.fa-share-square:before {
  content: "\f14d";
}
.fa-compass:before {
  content: "\f14e";
}
.fa-toggle-down:before,
.fa-caret-square-o-down:before {
  content: "\f150";
}
.fa-toggle-up:before,
.fa-caret-square-o-up:before {
  content: "\f151";
}
.fa-toggle-right:before,
.fa-caret-square-o-right:before {
  content: "\f152";
}
.fa-euro:before,
.fa-eur:before {
  content: "\f153";
}
.fa-gbp:before {
  content: "\f154";
}
.fa-dollar:before,
.fa-usd:before {
  content: "\f155";
}
.fa-rupee:before,
.fa-inr:before {
  content: "\f156";
}
.fa-cny:before,
.fa-rmb:before,
.fa-yen:before,
.fa-jpy:before {
  content: "\f157";
}
.fa-ruble:before,
.fa-rouble:before,
.fa-rub:before {
  content: "\f158";
}
.fa-won:before,
.fa-krw:before {
  content: "\f159";
}
.fa-bitcoin:before,
.fa-btc:before {
  content: "\f15a";
}
.fa-file:before {
  content: "\f15b";
}
.fa-file-text:before {
  content: "\f15c";
}
.fa-sort-alpha-asc:before {
  content: "\f15d";
}
.fa-sort-alpha-desc:before {
  content: "\f15e";
}
.fa-sort-amount-asc:before {
  content: "\f160";
}
.fa-sort-amount-desc:before {
  content: "\f161";
}
.fa-sort-numeric-asc:before {
  content: "\f162";
}
.fa-sort-numeric-desc:before {
  content: "\f163";
}
.fa-thumbs-up:before {
  content: "\f164";
}
.fa-thumbs-down:before {
  content: "\f165";
}
.fa-youtube-square:before {
  content: "\f166";
}
.fa-youtube:before {
  content: "\f167";
}
.fa-xing:before {
  content: "\f168";
}
.fa-xing-square:before {
  content: "\f169";
}
.fa-youtube-play:before {
  content: "\f16a";
}
.fa-dropbox:before {
  content: "\f16b";
}
.fa-stack-overflow:before {
  content: "\f16c";
}
.fa-instagram:before {
  content: "\f16d";
}
.fa-flickr:before {
  content: "\f16e";
}
.fa-adn:before {
  content: "\f170";
}
.fa-bitbucket:before {
  content: "\f171";
}
.fa-bitbucket-square:before {
  content: "\f172";
}
.fa-tumblr:before {
  content: "\f173";
}
.fa-tumblr-square:before {
  content: "\f174";
}
.fa-long-arrow-down:before {
  content: "\f175";
}
.fa-long-arrow-up:before {
  content: "\f176";
}
.fa-long-arrow-left:before {
  content: "\f177";
}
.fa-long-arrow-right:before {
  content: "\f178";
}
.fa-apple:before {
  content: "\f179";
}
.fa-windows:before {
  content: "\f17a";
}
.fa-android:before {
  content: "\f17b";
}
.fa-linux:before {
  content: "\f17c";
}
.fa-dribbble:before {
  content: "\f17d";
}
.fa-skype:before {
  content: "\f17e";
}
.fa-foursquare:before {
  content: "\f180";
}
.fa-trello:before {
  content: "\f181";
}
.fa-female:before {
  content: "\f182";
}
.fa-male:before {
  content: "\f183";
}
.fa-gittip:before {
  content: "\f184";
}
.fa-sun-o:before {
  content: "\f185";
}
.fa-moon-o:before {
  content: "\f186";
}
.fa-archive:before {
  content: "\f187";
}
.fa-bug:before {
  content: "\f188";
}
.fa-vk:before {
  content: "\f189";
}
.fa-weibo:before {
  content: "\f18a";
}
.fa-renren:before {
  content: "\f18b";
}
.fa-pagelines:before {
  content: "\f18c";
}
.fa-stack-exchange:before {
  content: "\f18d";
}
.fa-arrow-circle-o-right:before {
  content: "\f18e";
}
.fa-arrow-circle-o-left:before {
  content: "\f190";
}
.fa-toggle-left:before,
.fa-caret-square-o-left:before {
  content: "\f191";
}
.fa-dot-circle-o:before {
  content: "\f192";
}
.fa-wheelchair:before {
  content: "\f193";
}
.fa-vimeo-square:before {
  content: "\f194";
}
.fa-turkish-lira:before,
.fa-try:before {
  content: "\f195";
}
.fa-plus-square-o:before {
  content: "\f196";
}
.fa-space-shuttle:before {
  content: "\f197";
}
.fa-slack:before {
  content: "\f198";
}
.fa-envelope-square:before {
  content: "\f199";
}
.fa-wordpress:before {
  content: "\f19a";
}
.fa-openid:before {
  content: "\f19b";
}
.fa-institution:before,
.fa-bank:before,
.fa-university:before {
  content: "\f19c";
}
.fa-mortar-board:before,
.fa-graduation-cap:before {
  content: "\f19d";
}
.fa-yahoo:before {
  content: "\f19e";
}
.fa-google:before {
  content: "\f1a0";
}
.fa-reddit:before {
  content: "\f1a1";
}
.fa-reddit-square:before {
  content: "\f1a2";
}
.fa-stumbleupon-circle:before {
  content: "\f1a3";
}
.fa-stumbleupon:before {
  content: "\f1a4";
}
.fa-delicious:before {
  content: "\f1a5";
}
.fa-digg:before {
  content: "\f1a6";
}
.fa-pied-piper:before {
  content: "\f1a7";
}
.fa-pied-piper-alt:before {
  content: "\f1a8";
}
.fa-drupal:before {
  content: "\f1a9";
}
.fa-joomla:before {
  content: "\f1aa";
}
.fa-language:before {
  content: "\f1ab";
}
.fa-fax:before {
  content: "\f1ac";
}
.fa-building:before {
  content: "\f1ad";
}
.fa-child:before {
  content: "\f1ae";
}
.fa-paw:before {
  content: "\f1b0";
}
.fa-spoon:before {
  content: "\f1b1";
}
.fa-cube:before {
  content: "\f1b2";
}
.fa-cubes:before {
  content: "\f1b3";
}
.fa-behance:before {
  content: "\f1b4";
}
.fa-behance-square:before {
  content: "\f1b5";
}
.fa-steam:before {
  content: "\f1b6";
}
.fa-steam-square:before {
  content: "\f1b7";
}
.fa-recycle:before {
  content: "\f1b8";
}
.fa-automobile:before,
.fa-car:before {
  content: "\f1b9";
}
.fa-cab:before,
.fa-taxi:before {
  content: "\f1ba";
}
.fa-tree:before {
  content: "\f1bb";
}
.fa-spotify:before {
  content: "\f1bc";
}
.fa-deviantart:before {
  content: "\f1bd";
}
.fa-soundcloud:before {
  content: "\f1be";
}
.fa-database:before {
  content: "\f1c0";
}
.fa-file-pdf-o:before {
  content: "\f1c1";
}
.fa-file-word-o:before {
  content: "\f1c2";
}
.fa-file-excel-o:before {
  content: "\f1c3";
}
.fa-file-powerpoint-o:before {
  content: "\f1c4";
}
.fa-file-photo-o:before,
.fa-file-picture-o:before,
.fa-file-image-o:before {
  content: "\f1c5";
}
.fa-file-zip-o:before,
.fa-file-archive-o:before {
  content: "\f1c6";
}
.fa-file-sound-o:before,
.fa-file-audio-o:before {
  content: "\f1c7";
}
.fa-file-movie-o:before,
.fa-file-video-o:before {
  content: "\f1c8";
}
.fa-file-code-o:before {
  content: "\f1c9";
}
.fa-vine:before {
  content: "\f1ca";
}
.fa-codepen:before {
  content: "\f1cb";
}
.fa-jsfiddle:before {
  content: "\f1cc";
}
.fa-life-bouy:before,
.fa-life-buoy:before,
.fa-life-saver:before,
.fa-support:before,
.fa-life-ring:before {
  content: "\f1cd";
}
.fa-circle-o-notch:before {
  content: "\f1ce";
}
.fa-ra:before,
.fa-rebel:before {
  content: "\f1d0";
}
.fa-ge:before,
.fa-empire:before {
  content: "\f1d1";
}
.fa-git-square:before {
  content: "\f1d2";
}
.fa-git:before {
  content: "\f1d3";
}
.fa-hacker-news:before {
  content: "\f1d4";
}
.fa-tencent-weibo:before {
  content: "\f1d5";
}
.fa-qq:before {
  content: "\f1d6";
}
.fa-wechat:before,
.fa-weixin:before {
  content: "\f1d7";
}
.fa-send:before,
.fa-paper-plane:before {
  content: "\f1d8";
}
.fa-send-o:before,
.fa-paper-plane-o:before {
  content: "\f1d9";
}
.fa-history:before {
  content: "\f1da";
}
.fa-circle-thin:before {
  content: "\f1db";
}
.fa-header:before {
  content: "\f1dc";
}
.fa-paragraph:before {
  content: "\f1dd";
}
.fa-sliders:before {
  content: "\f1de";
}
.fa-share-alt:before {
  content: "\f1e0";
}
.fa-share-alt-square:before {
  content: "\f1e1";
}
.fa-bomb:before {
  content: "\f1e2";
}
.fa-soccer-ball-o:before,
.fa-futbol-o:before {
  content: "\f1e3";
}
.fa-tty:before {
  content: "\f1e4";
}
.fa-binoculars:before {
  content: "\f1e5";
}
.fa-plug:before {
  content: "\f1e6";
}
.fa-slideshare:before {
  content: "\f1e7";
}
.fa-twitch:before {
  content: "\f1e8";
}
.fa-yelp:before {
  content: "\f1e9";
}
.fa-newspaper-o:before {
  content: "\f1ea";
}
.fa-wifi:before {
  content: "\f1eb";
}
.fa-calculator:before {
  content: "\f1ec";
}
.fa-paypal:before {
  content: "\f1ed";
}
.fa-google-wallet:before {
  content: "\f1ee";
}
.fa-cc-visa:before {
  content: "\f1f0";
}
.fa-cc-mastercard:before {
  content: "\f1f1";
}
.fa-cc-discover:before {
  content: "\f1f2";
}
.fa-cc-amex:before {
  content: "\f1f3";
}
.fa-cc-paypal:before {
  content: "\f1f4";
}
.fa-cc-stripe:before {
  content: "\f1f5";
}
.fa-bell-slash:before {
  content: "\f1f6";
}
.fa-bell-slash-o:before {
  content: "\f1f7";
}
.fa-trash:before {
  content: "\f1f8";
}
.fa-copyright:before {
  content: "\f1f9";
}
.fa-at:before {
  content: "\f1fa";
}
.fa-eyedropper:before {
  content: "\f1fb";
}
.fa-paint-brush:before {
  content: "\f1fc";
}
.fa-birthday-cake:before {
  content: "\f1fd";
}
.fa-area-chart:before {
  content: "\f1fe";
}
.fa-pie-chart:before {
  content: "\f200";
}
.fa-line-chart:before {
  content: "\f201";
}
.fa-lastfm:before {
  content: "\f202";
}
.fa-lastfm-square:before {
  content: "\f203";
}
.fa-toggle-off:before {
  content: "\f204";
}
.fa-toggle-on:before {
  content: "\f205";
}
.fa-bicycle:before {
  content: "\f206";
}
.fa-bus:before {
  content: "\f207";
}
.fa-ioxhost:before {
  content: "\f208";
}
.fa-angellist:before {
  content: "\f209";
}
.fa-cc:before {
  content: "\f20a";
}
.fa-shekel:before,
.fa-sheqel:before,
.fa-ils:before {
  content: "\f20b";
}
.fa-meanpath:before {
  content: "\f20c";
}
/*!
*
* IPython base
*
*/
.modal.fade .modal-dialog {
  -webkit-transform: translate(0, 0);
  -ms-transform: translate(0, 0);
  -o-transform: translate(0, 0);
  transform: translate(0, 0);
}
code {
  color: #000;
}
pre {
  font-size: inherit;
  line-height: inherit;
}
label {
  font-weight: normal;
}
/* Make the page background atleast 100% the height of the view port */
/* Make the page itself atleast 70% the height of the view port */
.border-box-sizing {
  box-sizing: border-box;
  -moz-box-sizing: border-box;
  -webkit-box-sizing: border-box;
}
.corner-all {
  border-radius: 2px;
}
.no-padding {
  padding: 0px;
}
/* Flexible box model classes */
/* Taken from Alex Russell http://infrequently.org/2009/08/css-3-progress/ */
/* This file is a compatability layer.  It allows the usage of flexible box 
model layouts accross multiple browsers, including older browsers.  The newest,
universal implementation of the flexible box model is used when available (see
`Modern browsers` comments below).  Browsers that are known to implement this 
new spec completely include:

    Firefox 28.0+
    Chrome 29.0+
    Internet Explorer 11+ 
    Opera 17.0+

Browsers not listed, including Safari, are supported via the styling under the
`Old browsers` comments below.
*/
.hbox {
  /* Old browsers */
  display: -webkit-box;
  -webkit-box-orient: horizontal;
  -webkit-box-align: stretch;
  display: -moz-box;
  -moz-box-orient: horizontal;
  -moz-box-align: stretch;
  display: box;
  box-orient: horizontal;
  box-align: stretch;
  /* Modern browsers */
  display: flex;
  flex-direction: row;
  align-items: stretch;
}
.hbox > * {
  /* Old browsers */
  -webkit-box-flex: 0;
  -moz-box-flex: 0;
  box-flex: 0;
  /* Modern browsers */
  flex: none;
}
.vbox {
  /* Old browsers */
  display: -webkit-box;
  -webkit-box-orient: vertical;
  -webkit-box-align: stretch;
  display: -moz-box;
  -moz-box-orient: vertical;
  -moz-box-align: stretch;
  display: box;
  box-orient: vertical;
  box-align: stretch;
  /* Modern browsers */
  display: flex;
  flex-direction: column;
  align-items: stretch;
}
.vbox > * {
  /* Old browsers */
  -webkit-box-flex: 0;
  -moz-box-flex: 0;
  box-flex: 0;
  /* Modern browsers */
  flex: none;
}
.hbox.reverse,
.vbox.reverse,
.reverse {
  /* Old browsers */
  -webkit-box-direction: reverse;
  -moz-box-direction: reverse;
  box-direction: reverse;
  /* Modern browsers */
  flex-direction: row-reverse;
}
.hbox.box-flex0,
.vbox.box-flex0,
.box-flex0 {
  /* Old browsers */
  -webkit-box-flex: 0;
  -moz-box-flex: 0;
  box-flex: 0;
  /* Modern browsers */
  flex: none;
  width: auto;
}
.hbox.box-flex1,
.vbox.box-flex1,
.box-flex1 {
  /* Old browsers */
  -webkit-box-flex: 1;
  -moz-box-flex: 1;
  box-flex: 1;
  /* Modern browsers */
  flex: 1;
}
.hbox.box-flex,
.vbox.box-flex,
.box-flex {
  /* Old browsers */
  /* Old browsers */
  -webkit-box-flex: 1;
  -moz-box-flex: 1;
  box-flex: 1;
  /* Modern browsers */
  flex: 1;
}
.hbox.box-flex2,
.vbox.box-flex2,
.box-flex2 {
  /* Old browsers */
  -webkit-box-flex: 2;
  -moz-box-flex: 2;
  box-flex: 2;
  /* Modern browsers */
  flex: 2;
}
.box-group1 {
  /*  Deprecated */
  -webkit-box-flex-group: 1;
  -moz-box-flex-group: 1;
  box-flex-group: 1;
}
.box-group2 {
  /* Deprecated */
  -webkit-box-flex-group: 2;
  -moz-box-flex-group: 2;
  box-flex-group: 2;
}
.hbox.start,
.vbox.start,
.start {
  /* Old browsers */
  -webkit-box-pack: start;
  -moz-box-pack: start;
  box-pack: start;
  /* Modern browsers */
  justify-content: flex-start;
}
.hbox.end,
.vbox.end,
.end {
  /* Old browsers */
  -webkit-box-pack: end;
  -moz-box-pack: end;
  box-pack: end;
  /* Modern browsers */
  justify-content: flex-end;
}
.hbox.center,
.vbox.center,
.center {
  /* Old browsers */
  -webkit-box-pack: center;
  -moz-box-pack: center;
  box-pack: center;
  /* Modern browsers */
  justify-content: center;
}
.hbox.baseline,
.vbox.baseline,
.baseline {
  /* Old browsers */
  -webkit-box-pack: baseline;
  -moz-box-pack: baseline;
  box-pack: baseline;
  /* Modern browsers */
  justify-content: baseline;
}
.hbox.stretch,
.vbox.stretch,
.stretch {
  /* Old browsers */
  -webkit-box-pack: stretch;
  -moz-box-pack: stretch;
  box-pack: stretch;
  /* Modern browsers */
  justify-content: stretch;
}
.hbox.align-start,
.vbox.align-start,
.align-start {
  /* Old browsers */
  -webkit-box-align: start;
  -moz-box-align: start;
  box-align: start;
  /* Modern browsers */
  align-items: flex-start;
}
.hbox.align-end,
.vbox.align-end,
.align-end {
  /* Old browsers */
  -webkit-box-align: end;
  -moz-box-align: end;
  box-align: end;
  /* Modern browsers */
  align-items: flex-end;
}
.hbox.align-center,
.vbox.align-center,
.align-center {
  /* Old browsers */
  -webkit-box-align: center;
  -moz-box-align: center;
  box-align: center;
  /* Modern browsers */
  align-items: center;
}
.hbox.align-baseline,
.vbox.align-baseline,
.align-baseline {
  /* Old browsers */
  -webkit-box-align: baseline;
  -moz-box-align: baseline;
  box-align: baseline;
  /* Modern browsers */
  align-items: baseline;
}
.hbox.align-stretch,
.vbox.align-stretch,
.align-stretch {
  /* Old browsers */
  -webkit-box-align: stretch;
  -moz-box-align: stretch;
  box-align: stretch;
  /* Modern browsers */
  align-items: stretch;
}
div.error {
  margin: 2em;
  text-align: center;
}
div.error > h1 {
  font-size: 500%;
  line-height: normal;
}
div.error > p {
  font-size: 200%;
  line-height: normal;
}
div.traceback-wrapper {
  text-align: left;
  max-width: 800px;
  margin: auto;
}
/**
 * Primary styles
 *
 * Author: Jupyter Development Team
 */
body {
  background-color: #fff;
  /* This makes sure that the body covers the entire window and needs to
       be in a different element than the display: box in wrapper below */
  position: absolute;
  left: 0px;
  right: 0px;
  top: 0px;
  bottom: 0px;
  overflow: visible;
}
body > #header {
  /* Initially hidden to prevent FLOUC */
  display: none;
  background-color: #fff;
  /* Display over codemirror */
  position: relative;
  z-index: 100;
}
body > #header #header-container {
  padding-bottom: 5px;
  padding-top: 5px;
  box-sizing: border-box;
  -moz-box-sizing: border-box;
  -webkit-box-sizing: border-box;
}
body > #header .header-bar {
  width: 100%;
  height: 1px;
  background: #e7e7e7;
  margin-bottom: -1px;
}
@media print {
  body > #header {
    display: none !important;
  }
}
#header-spacer {
  width: 100%;
  visibility: hidden;
}
@media print {
  #header-spacer {
    display: none;
  }
}
#ipython_notebook {
  padding-left: 0px;
  padding-top: 1px;
  padding-bottom: 1px;
}
@media (max-width: 991px) {
  #ipython_notebook {
    margin-left: 10px;
  }
}
[dir="rtl"] #ipython_notebook {
  float: right !important;
}
#noscript {
  width: auto;
  padding-top: 16px;
  padding-bottom: 16px;
  text-align: center;
  font-size: 22px;
  color: red;
  font-weight: bold;
}
#ipython_notebook img {
  height: 28px;
}
#site {
  width: 100%;
  display: none;
  box-sizing: border-box;
  -moz-box-sizing: border-box;
  -webkit-box-sizing: border-box;
  overflow: auto;
}
@media print {
  #site {
    height: auto !important;
  }
}
/* Smaller buttons */
.ui-button .ui-button-text {
  padding: 0.2em 0.8em;
  font-size: 77%;
}
input.ui-button {
  padding: 0.3em 0.9em;
}
span#login_widget {
  float: right;
}
span#login_widget > .button,
#logout {
  color: #333;
  background-color: #fff;
  border-color: #ccc;
}
span#login_widget > .button:focus,
#logout:focus,
span#login_widget > .button.focus,
#logout.focus {
  color: #333;
  background-color: #e6e6e6;
  border-color: #8c8c8c;
}
span#login_widget > .button:hover,
#logout:hover {
  color: #333;
  background-color: #e6e6e6;
  border-color: #adadad;
}
span#login_widget > .button:active,
#logout:active,
span#login_widget > .button.active,
#logout.active,
.open > .dropdown-togglespan#login_widget > .button,
.open > .dropdown-toggle#logout {
  color: #333;
  background-color: #e6e6e6;
  border-color: #adadad;
}
span#login_widget > .button:active:hover,
#logout:active:hover,
span#login_widget > .button.active:hover,
#logout.active:hover,
.open > .dropdown-togglespan#login_widget > .button:hover,
.open > .dropdown-toggle#logout:hover,
span#login_widget > .button:active:focus,
#logout:active:focus,
span#login_widget > .button.active:focus,
#logout.active:focus,
.open > .dropdown-togglespan#login_widget > .button:focus,
.open > .dropdown-toggle#logout:focus,
span#login_widget > .button:active.focus,
#logout:active.focus,
span#login_widget > .button.active.focus,
#logout.active.focus,
.open > .dropdown-togglespan#login_widget > .button.focus,
.open > .dropdown-toggle#logout.focus {
  color: #333;
  background-color: #d4d4d4;
  border-color: #8c8c8c;
}
span#login_widget > .button:active,
#logout:active,
span#login_widget > .button.active,
#logout.active,
.open > .dropdown-togglespan#login_widget > .button,
.open > .dropdown-toggle#logout {
  background-image: none;
}
span#login_widget > .button.disabled:hover,
#logout.disabled:hover,
span#login_widget > .button[disabled]:hover,
#logout[disabled]:hover,
fieldset[disabled] span#login_widget > .button:hover,
fieldset[disabled] #logout:hover,
span#login_widget > .button.disabled:focus,
#logout.disabled:focus,
span#login_widget > .button[disabled]:focus,
#logout[disabled]:focus,
fieldset[disabled] span#login_widget > .button:focus,
fieldset[disabled] #logout:focus,
span#login_widget > .button.disabled.focus,
#logout.disabled.focus,
span#login_widget > .button[disabled].focus,
#logout[disabled].focus,
fieldset[disabled] span#login_widget > .button.focus,
fieldset[disabled] #logout.focus {
  background-color: #fff;
  border-color: #ccc;
}
span#login_widget > .button .badge,
#logout .badge {
  color: #fff;
  background-color: #333;
}
.nav-header {
  text-transform: none;
}
#header > span {
  margin-top: 10px;
}
.modal_stretch .modal-dialog {
  /* Old browsers */
  display: -webkit-box;
  -webkit-box-orient: vertical;
  -webkit-box-align: stretch;
  display: -moz-box;
  -moz-box-orient: vertical;
  -moz-box-align: stretch;
  display: box;
  box-orient: vertical;
  box-align: stretch;
  /* Modern browsers */
  display: flex;
  flex-direction: column;
  align-items: stretch;
  min-height: 80vh;
}
.modal_stretch .modal-dialog .modal-body {
  max-height: calc(100vh - 200px);
  overflow: auto;
  flex: 1;
}
@media (min-width: 768px) {
  .modal .modal-dialog {
    width: 700px;
  }
}
@media (min-width: 768px) {
  select.form-control {
    margin-left: 12px;
    margin-right: 12px;
  }
}
/*!
*
* IPython auth
*
*/
.center-nav {
  display: inline-block;
  margin-bottom: -4px;
}
/*!
*
* IPython tree view
*
*/
/* We need an invisible input field on top of the sentense*/
/* "Drag file onto the list ..." */
.alternate_upload {
  background-color: none;
  display: inline;
}
.alternate_upload.form {
  padding: 0;
  margin: 0;
}
.alternate_upload input.fileinput {
  text-align: center;
  vertical-align: middle;
  display: inline;
  opacity: 0;
  z-index: 2;
  width: 12ex;
  margin-right: -12ex;
}
.alternate_upload .btn-upload {
  height: 22px;
}
/**
 * Primary styles
 *
 * Author: Jupyter Development Team
 */
[dir="rtl"] #tabs li {
  float: right;
}
ul#tabs {
  margin-bottom: 4px;
}
[dir="rtl"] ul#tabs {
  margin-right: 0px;
}
ul#tabs a {
  padding-top: 6px;
  padding-bottom: 4px;
}
ul.breadcrumb a:focus,
ul.breadcrumb a:hover {
  text-decoration: none;
}
ul.breadcrumb i.icon-home {
  font-size: 16px;
  margin-right: 4px;
}
ul.breadcrumb span {
  color: #5e5e5e;
}
.list_toolbar {
  padding: 4px 0 4px 0;
  vertical-align: middle;
}
.list_toolbar .tree-buttons {
  padding-top: 1px;
}
[dir="rtl"] .list_toolbar .tree-buttons {
  float: left !important;
}
[dir="rtl"] .list_toolbar .pull-right {
  padding-top: 1px;
  float: left !important;
}
[dir="rtl"] .list_toolbar .pull-left {
  float: right !important;
}
.dynamic-buttons {
  padding-top: 3px;
  display: inline-block;
}
.list_toolbar [class*="span"] {
  min-height: 24px;
}
.list_header {
  font-weight: bold;
  background-color: #EEE;
}
.list_placeholder {
  font-weight: bold;
  padding-top: 4px;
  padding-bottom: 4px;
  padding-left: 7px;
  padding-right: 7px;
}
.list_container {
  margin-top: 4px;
  margin-bottom: 20px;
  border: 1px solid #ddd;
  border-radius: 2px;
}
.list_container > div {
  border-bottom: 1px solid #ddd;
}
.list_container > div:hover .list-item {
  background-color: red;
}
.list_container > div:last-child {
  border: none;
}
.list_item:hover .list_item {
  background-color: #ddd;
}
.list_item a {
  text-decoration: none;
}
.list_item:hover {
  background-color: #fafafa;
}
.list_header > div,
.list_item > div {
  padding-top: 4px;
  padding-bottom: 4px;
  padding-left: 7px;
  padding-right: 7px;
  line-height: 22px;
}
.list_header > div input,
.list_item > div input {
  margin-right: 7px;
  margin-left: 14px;
  vertical-align: baseline;
  line-height: 22px;
  position: relative;
  top: -1px;
}
.list_header > div .item_link,
.list_item > div .item_link {
  margin-left: -1px;
  vertical-align: baseline;
  line-height: 22px;
}
.new-file input[type=checkbox] {
  visibility: hidden;
}
.item_name {
  line-height: 22px;
  height: 24px;
}
.item_icon {
  font-size: 14px;
  color: #5e5e5e;
  margin-right: 7px;
  margin-left: 7px;
  line-height: 22px;
  vertical-align: baseline;
}
.item_buttons {
  line-height: 1em;
  margin-left: -5px;
}
.item_buttons .btn,
.item_buttons .btn-group,
.item_buttons .input-group {
  float: left;
}
.item_buttons > .btn,
.item_buttons > .btn-group,
.item_buttons > .input-group {
  margin-left: 5px;
}
.item_buttons .btn {
  min-width: 13ex;
}
.item_buttons .running-indicator {
  padding-top: 4px;
  color: #5cb85c;
}
.item_buttons .kernel-name {
  padding-top: 4px;
  color: #5bc0de;
  margin-right: 7px;
  float: left;
}
.toolbar_info {
  height: 24px;
  line-height: 24px;
}
.list_item input:not([type=checkbox]) {
  padding-top: 3px;
  padding-bottom: 3px;
  height: 22px;
  line-height: 14px;
  margin: 0px;
}
.highlight_text {
  color: blue;
}
#project_name {
  display: inline-block;
  padding-left: 7px;
  margin-left: -2px;
}
#project_name > .breadcrumb {
  padding: 0px;
  margin-bottom: 0px;
  background-color: transparent;
  font-weight: bold;
}
#tree-selector {
  padding-right: 0px;
}
[dir="rtl"] #tree-selector a {
  float: right;
}
#button-select-all {
  min-width: 50px;
}
#select-all {
  margin-left: 7px;
  margin-right: 2px;
}
.menu_icon {
  margin-right: 2px;
}
.tab-content .row {
  margin-left: 0px;
  margin-right: 0px;
}
.folder_icon:before {
  display: inline-block;
  font: normal normal normal 14px/1 FontAwesome;
  font-size: inherit;
  text-rendering: auto;
  -webkit-font-smoothing: antialiased;
  -moz-osx-font-smoothing: grayscale;
  content: "\f114";
}
.folder_icon:before.pull-left {
  margin-right: .3em;
}
.folder_icon:before.pull-right {
  margin-left: .3em;
}
.notebook_icon:before {
  display: inline-block;
  font: normal normal normal 14px/1 FontAwesome;
  font-size: inherit;
  text-rendering: auto;
  -webkit-font-smoothing: antialiased;
  -moz-osx-font-smoothing: grayscale;
  content: "\f02d";
  position: relative;
  top: -1px;
}
.notebook_icon:before.pull-left {
  margin-right: .3em;
}
.notebook_icon:before.pull-right {
  margin-left: .3em;
}
.running_notebook_icon:before {
  display: inline-block;
  font: normal normal normal 14px/1 FontAwesome;
  font-size: inherit;
  text-rendering: auto;
  -webkit-font-smoothing: antialiased;
  -moz-osx-font-smoothing: grayscale;
  content: "\f02d";
  position: relative;
  top: -1px;
  color: #5cb85c;
}
.running_notebook_icon:before.pull-left {
  margin-right: .3em;
}
.running_notebook_icon:before.pull-right {
  margin-left: .3em;
}
.file_icon:before {
  display: inline-block;
  font: normal normal normal 14px/1 FontAwesome;
  font-size: inherit;
  text-rendering: auto;
  -webkit-font-smoothing: antialiased;
  -moz-osx-font-smoothing: grayscale;
  content: "\f016";
  position: relative;
  top: -2px;
}
.file_icon:before.pull-left {
  margin-right: .3em;
}
.file_icon:before.pull-right {
  margin-left: .3em;
}
#notebook_toolbar .pull-right {
  padding-top: 0px;
  margin-right: -1px;
}
ul#new-menu {
  left: auto;
  right: 0;
}
[dir="rtl"] #new-menu {
  text-align: right;
}
.kernel-menu-icon {
  padding-right: 12px;
  width: 24px;
  content: "\f096";
}
.kernel-menu-icon:before {
  content: "\f096";
}
.kernel-menu-icon-current:before {
  content: "\f00c";
}
#tab_content {
  padding-top: 20px;
}
#running .panel-group .panel {
  margin-top: 3px;
  margin-bottom: 1em;
}
#running .panel-group .panel .panel-heading {
  background-color: #EEE;
  padding-top: 4px;
  padding-bottom: 4px;
  padding-left: 7px;
  padding-right: 7px;
  line-height: 22px;
}
#running .panel-group .panel .panel-heading a:focus,
#running .panel-group .panel .panel-heading a:hover {
  text-decoration: none;
}
#running .panel-group .panel .panel-body {
  padding: 0px;
}
#running .panel-group .panel .panel-body .list_container {
  margin-top: 0px;
  margin-bottom: 0px;
  border: 0px;
  border-radius: 0px;
}
#running .panel-group .panel .panel-body .list_container .list_item {
  border-bottom: 1px solid #ddd;
}
#running .panel-group .panel .panel-body .list_container .list_item:last-child {
  border-bottom: 0px;
}
[dir="rtl"] #running .col-sm-8 {
  float: right !important;
}
.delete-button {
  display: none;
}
.duplicate-button {
  display: none;
}
.rename-button {
  display: none;
}
.shutdown-button {
  display: none;
}
.dynamic-instructions {
  display: inline-block;
  padding-top: 4px;
}
/*!
*
* IPython text editor webapp
*
*/
.selected-keymap i.fa {
  padding: 0px 5px;
}
.selected-keymap i.fa:before {
  content: "\f00c";
}
#mode-menu {
  overflow: auto;
  max-height: 20em;
}
.edit_app #header {
  -webkit-box-shadow: 0px 0px 12px 1px rgba(87, 87, 87, 0.2);
  box-shadow: 0px 0px 12px 1px rgba(87, 87, 87, 0.2);
}
.edit_app #menubar .navbar {
  /* Use a negative 1 bottom margin, so the border overlaps the border of the
    header */
  margin-bottom: -1px;
}
.dirty-indicator {
  display: inline-block;
  font: normal normal normal 14px/1 FontAwesome;
  font-size: inherit;
  text-rendering: auto;
  -webkit-font-smoothing: antialiased;
  -moz-osx-font-smoothing: grayscale;
  width: 20px;
}
.dirty-indicator.pull-left {
  margin-right: .3em;
}
.dirty-indicator.pull-right {
  margin-left: .3em;
}
.dirty-indicator-dirty {
  display: inline-block;
  font: normal normal normal 14px/1 FontAwesome;
  font-size: inherit;
  text-rendering: auto;
  -webkit-font-smoothing: antialiased;
  -moz-osx-font-smoothing: grayscale;
  width: 20px;
}
.dirty-indicator-dirty.pull-left {
  margin-right: .3em;
}
.dirty-indicator-dirty.pull-right {
  margin-left: .3em;
}
.dirty-indicator-clean {
  display: inline-block;
  font: normal normal normal 14px/1 FontAwesome;
  font-size: inherit;
  text-rendering: auto;
  -webkit-font-smoothing: antialiased;
  -moz-osx-font-smoothing: grayscale;
  width: 20px;
}
.dirty-indicator-clean.pull-left {
  margin-right: .3em;
}
.dirty-indicator-clean.pull-right {
  margin-left: .3em;
}
.dirty-indicator-clean:before {
  display: inline-block;
  font: normal normal normal 14px/1 FontAwesome;
  font-size: inherit;
  text-rendering: auto;
  -webkit-font-smoothing: antialiased;
  -moz-osx-font-smoothing: grayscale;
  content: "\f00c";
}
.dirty-indicator-clean:before.pull-left {
  margin-right: .3em;
}
.dirty-indicator-clean:before.pull-right {
  margin-left: .3em;
}
#filename {
  font-size: 16pt;
  display: table;
  padding: 0px 5px;
}
#current-mode {
  padding-left: 5px;
  padding-right: 5px;
}
#texteditor-backdrop {
  padding-top: 20px;
  padding-bottom: 20px;
}
@media not print {
  #texteditor-backdrop {
    background-color: #EEE;
  }
}
@media print {
  #texteditor-backdrop #texteditor-container .CodeMirror-gutter,
  #texteditor-backdrop #texteditor-container .CodeMirror-gutters {
    background-color: #fff;
  }
}
@media not print {
  #texteditor-backdrop #texteditor-container .CodeMirror-gutter,
  #texteditor-backdrop #texteditor-container .CodeMirror-gutters {
    background-color: #fff;
  }
}
@media not print {
  #texteditor-backdrop #texteditor-container {
    padding: 0px;
    background-color: #fff;
    -webkit-box-shadow: 0px 0px 12px 1px rgba(87, 87, 87, 0.2);
    box-shadow: 0px 0px 12px 1px rgba(87, 87, 87, 0.2);
  }
}
/*!
*
* IPython notebook
*
*/
/* CSS font colors for translated ANSI colors. */
.ansibold {
  font-weight: bold;
}
/* use dark versions for foreground, to improve visibility */
.ansiblack {
  color: black;
}
.ansired {
  color: darkred;
}
.ansigreen {
  color: darkgreen;
}
.ansiyellow {
  color: #c4a000;
}
.ansiblue {
  color: darkblue;
}
.ansipurple {
  color: darkviolet;
}
.ansicyan {
  color: steelblue;
}
.ansigray {
  color: gray;
}
/* and light for background, for the same reason */
.ansibgblack {
  background-color: black;
}
.ansibgred {
  background-color: red;
}
.ansibggreen {
  background-color: green;
}
.ansibgyellow {
  background-color: yellow;
}
.ansibgblue {
  background-color: blue;
}
.ansibgpurple {
  background-color: magenta;
}
.ansibgcyan {
  background-color: cyan;
}
.ansibggray {
  background-color: gray;
}
div.cell {
  /* Old browsers */
  display: -webkit-box;
  -webkit-box-orient: vertical;
  -webkit-box-align: stretch;
  display: -moz-box;
  -moz-box-orient: vertical;
  -moz-box-align: stretch;
  display: box;
  box-orient: vertical;
  box-align: stretch;
  /* Modern browsers */
  display: flex;
  flex-direction: column;
  align-items: stretch;
  border-radius: 2px;
  box-sizing: border-box;
  -moz-box-sizing: border-box;
  -webkit-box-sizing: border-box;
  border-width: 1px;
  border-style: solid;
  border-color: transparent;
  width: 100%;
  padding: 5px;
  /* This acts as a spacer between cells, that is outside the border */
  margin: 0px;
  outline: none;
  border-left-width: 1px;
  padding-left: 5px;
  background: linear-gradient(to right, transparent -40px, transparent 1px, transparent 1px, transparent 100%);
}
div.cell.jupyter-soft-selected {
  border-left-color: #90CAF9;
  border-left-color: #E3F2FD;
  border-left-width: 1px;
  padding-left: 5px;
  border-right-color: #E3F2FD;
  border-right-width: 1px;
  background: #E3F2FD;
}
@media print {
  div.cell.jupyter-soft-selected {
    border-color: transparent;
  }
}
div.cell.selected {
  border-color: #ababab;
  border-left-width: 0px;
  padding-left: 6px;
  background: linear-gradient(to right, #42A5F5 -40px, #42A5F5 5px, transparent 5px, transparent 100%);
}
@media print {
  div.cell.selected {
    border-color: transparent;
  }
}
div.cell.selected.jupyter-soft-selected {
  border-left-width: 0;
  padding-left: 6px;
  background: linear-gradient(to right, #42A5F5 -40px, #42A5F5 7px, #E3F2FD 7px, #E3F2FD 100%);
}
.edit_mode div.cell.selected {
  border-color: #66BB6A;
  border-left-width: 0px;
  padding-left: 6px;
  background: linear-gradient(to right, #66BB6A -40px, #66BB6A 5px, transparent 5px, transparent 100%);
}
@media print {
  .edit_mode div.cell.selected {
    border-color: transparent;
  }
}
.prompt {
  /* This needs to be wide enough for 3 digit prompt numbers: In[100]: */
  min-width: 14ex;
  /* This padding is tuned to match the padding on the CodeMirror editor. */
  padding: 0.4em;
  margin: 0px;
  font-family: monospace;
  text-align: right;
  /* This has to match that of the the CodeMirror class line-height below */
  line-height: 1.21429em;
  /* Don't highlight prompt number selection */
  -webkit-touch-callout: none;
  -webkit-user-select: none;
  -khtml-user-select: none;
  -moz-user-select: none;
  -ms-user-select: none;
  user-select: none;
  /* Use default cursor */
  cursor: default;
}
@media (max-width: 540px) {
  .prompt {
    text-align: left;
  }
}
div.inner_cell {
  min-width: 0;
  /* Old browsers */
  display: -webkit-box;
  -webkit-box-orient: vertical;
  -webkit-box-align: stretch;
  display: -moz-box;
  -moz-box-orient: vertical;
  -moz-box-align: stretch;
  display: box;
  box-orient: vertical;
  box-align: stretch;
  /* Modern browsers */
  display: flex;
  flex-direction: column;
  align-items: stretch;
  /* Old browsers */
  -webkit-box-flex: 1;
  -moz-box-flex: 1;
  box-flex: 1;
  /* Modern browsers */
  flex: 1;
}
/* input_area and input_prompt must match in top border and margin for alignment */
div.input_area {
  border: 1px solid #cfcfcf;
  border-radius: 2px;
  background: #f7f7f7;
  line-height: 1.21429em;
}
/* This is needed so that empty prompt areas can collapse to zero height when there
   is no content in the output_subarea and the prompt. The main purpose of this is
   to make sure that empty JavaScript output_subareas have no height. */
div.prompt:empty {
  padding-top: 0;
  padding-bottom: 0;
}
div.unrecognized_cell {
  padding: 5px 5px 5px 0px;
  /* Old browsers */
  display: -webkit-box;
  -webkit-box-orient: horizontal;
  -webkit-box-align: stretch;
  display: -moz-box;
  -moz-box-orient: horizontal;
  -moz-box-align: stretch;
  display: box;
  box-orient: horizontal;
  box-align: stretch;
  /* Modern browsers */
  display: flex;
  flex-direction: row;
  align-items: stretch;
}
div.unrecognized_cell .inner_cell {
  border-radius: 2px;
  padding: 5px;
  font-weight: bold;
  color: red;
  border: 1px solid #cfcfcf;
  background: #eaeaea;
}
div.unrecognized_cell .inner_cell a {
  color: inherit;
  text-decoration: none;
}
div.unrecognized_cell .inner_cell a:hover {
  color: inherit;
  text-decoration: none;
}
@media (max-width: 540px) {
  div.unrecognized_cell > div.prompt {
    display: none;
  }
}
div.code_cell {
  /* avoid page breaking on code cells when printing */
}
@media print {
  div.code_cell {
    page-break-inside: avoid;
  }
}
/* any special styling for code cells that are currently running goes here */
div.input {
  page-break-inside: avoid;
  /* Old browsers */
  display: -webkit-box;
  -webkit-box-orient: horizontal;
  -webkit-box-align: stretch;
  display: -moz-box;
  -moz-box-orient: horizontal;
  -moz-box-align: stretch;
  display: box;
  box-orient: horizontal;
  box-align: stretch;
  /* Modern browsers */
  display: flex;
  flex-direction: row;
  align-items: stretch;
}
@media (max-width: 540px) {
  div.input {
    /* Old browsers */
    display: -webkit-box;
    -webkit-box-orient: vertical;
    -webkit-box-align: stretch;
    display: -moz-box;
    -moz-box-orient: vertical;
    -moz-box-align: stretch;
    display: box;
    box-orient: vertical;
    box-align: stretch;
    /* Modern browsers */
    display: flex;
    flex-direction: column;
    align-items: stretch;
  }
}
/* input_area and input_prompt must match in top border and margin for alignment */
div.input_prompt {
  color: #303F9F;
  border-top: 1px solid transparent;
}
div.input_area > div.highlight {
  margin: 0.4em;
  border: none;
  padding: 0px;
  background-color: transparent;
}
div.input_area > div.highlight > pre {
  margin: 0px;
  border: none;
  padding: 0px;
  background-color: transparent;
}
/* The following gets added to the <head> if it is detected that the user has a
 * monospace font with inconsistent normal/bold/italic height.  See
 * notebookmain.js.  Such fonts will have keywords vertically offset with
 * respect to the rest of the text.  The user should select a better font.
 * See: https://github.com/ipython/ipython/issues/1503
 *
 * .CodeMirror span {
 *      vertical-align: bottom;
 * }
 */
.CodeMirror {
  line-height: 1.21429em;
  /* Changed from 1em to our global default */
  font-size: 14px;
  height: auto;
  /* Changed to auto to autogrow */
  background: none;
  /* Changed from white to allow our bg to show through */
}
.CodeMirror-scroll {
  /*  The CodeMirror docs are a bit fuzzy on if overflow-y should be hidden or visible.*/
  /*  We have found that if it is visible, vertical scrollbars appear with font size changes.*/
  overflow-y: hidden;
  overflow-x: auto;
}
.CodeMirror-lines {
  /* In CM2, this used to be 0.4em, but in CM3 it went to 4px. We need the em value because */
  /* we have set a different line-height and want this to scale with that. */
  padding: 0.4em;
}
.CodeMirror-linenumber {
  padding: 0 8px 0 4px;
}
.CodeMirror-gutters {
  border-bottom-left-radius: 2px;
  border-top-left-radius: 2px;
}
.CodeMirror pre {
  /* In CM3 this went to 4px from 0 in CM2. We need the 0 value because of how we size */
  /* .CodeMirror-lines */
  padding: 0;
  border: 0;
  border-radius: 0;
}
/*

Original style from softwaremaniacs.org (c) Ivan Sagalaev <Maniac@SoftwareManiacs.Org>
Adapted from GitHub theme

*/
.highlight-base {
  color: #000;
}
.highlight-variable {
  color: #000;
}
.highlight-variable-2 {
  color: #1a1a1a;
}
.highlight-variable-3 {
  color: #333333;
}
.highlight-string {
  color: #BA2121;
}
.highlight-comment {
  color: #408080;
  font-style: italic;
}
.highlight-number {
  color: #080;
}
.highlight-atom {
  color: #88F;
}
.highlight-keyword {
  color: #008000;
  font-weight: bold;
}
.highlight-builtin {
  color: #008000;
}
.highlight-error {
  color: #f00;
}
.highlight-operator {
  color: #AA22FF;
  font-weight: bold;
}
.highlight-meta {
  color: #AA22FF;
}
/* previously not defined, copying from default codemirror */
.highlight-def {
  color: #00f;
}
.highlight-string-2 {
  color: #f50;
}
.highlight-qualifier {
  color: #555;
}
.highlight-bracket {
  color: #997;
}
.highlight-tag {
  color: #170;
}
.highlight-attribute {
  color: #00c;
}
.highlight-header {
  color: blue;
}
.highlight-quote {
  color: #090;
}
.highlight-link {
  color: #00c;
}
/* apply the same style to codemirror */
.cm-s-ipython span.cm-keyword {
  color: #008000;
  font-weight: bold;
}
.cm-s-ipython span.cm-atom {
  color: #88F;
}
.cm-s-ipython span.cm-number {
  color: #080;
}
.cm-s-ipython span.cm-def {
  color: #00f;
}
.cm-s-ipython span.cm-variable {
  color: #000;
}
.cm-s-ipython span.cm-operator {
  color: #AA22FF;
  font-weight: bold;
}
.cm-s-ipython span.cm-variable-2 {
  color: #1a1a1a;
}
.cm-s-ipython span.cm-variable-3 {
  color: #333333;
}
.cm-s-ipython span.cm-comment {
  color: #408080;
  font-style: italic;
}
.cm-s-ipython span.cm-string {
  color: #BA2121;
}
.cm-s-ipython span.cm-string-2 {
  color: #f50;
}
.cm-s-ipython span.cm-meta {
  color: #AA22FF;
}
.cm-s-ipython span.cm-qualifier {
  color: #555;
}
.cm-s-ipython span.cm-builtin {
  color: #008000;
}
.cm-s-ipython span.cm-bracket {
  color: #997;
}
.cm-s-ipython span.cm-tag {
  color: #170;
}
.cm-s-ipython span.cm-attribute {
  color: #00c;
}
.cm-s-ipython span.cm-header {
  color: blue;
}
.cm-s-ipython span.cm-quote {
  color: #090;
}
.cm-s-ipython span.cm-link {
  color: #00c;
}
.cm-s-ipython span.cm-error {
  color: #f00;
}
.cm-s-ipython span.cm-tab {
  background: url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAADAAAAAMCAYAAAAkuj5RAAAAAXNSR0IArs4c6QAAAGFJREFUSMft1LsRQFAQheHPowAKoACx3IgEKtaEHujDjORSgWTH/ZOdnZOcM/sgk/kFFWY0qV8foQwS4MKBCS3qR6ixBJvElOobYAtivseIE120FaowJPN75GMu8j/LfMwNjh4HUpwg4LUAAAAASUVORK5CYII=);
  background-position: right;
  background-repeat: no-repeat;
}
div.output_wrapper {
  /* this position must be relative to enable descendents to be absolute within it */
  position: relative;
  /* Old browsers */
  display: -webkit-box;
  -webkit-box-orient: vertical;
  -webkit-box-align: stretch;
  display: -moz-box;
  -moz-box-orient: vertical;
  -moz-box-align: stretch;
  display: box;
  box-orient: vertical;
  box-align: stretch;
  /* Modern browsers */
  display: flex;
  flex-direction: column;
  align-items: stretch;
  z-index: 1;
}
/* class for the output area when it should be height-limited */
div.output_scroll {
  /* ideally, this would be max-height, but FF barfs all over that */
  height: 24em;
  /* FF needs this *and the wrapper* to specify full width, or it will shrinkwrap */
  width: 100%;
  overflow: auto;
  border-radius: 2px;
  -webkit-box-shadow: inset 0 2px 8px rgba(0, 0, 0, 0.8);
  box-shadow: inset 0 2px 8px rgba(0, 0, 0, 0.8);
  display: block;
}
/* output div while it is collapsed */
div.output_collapsed {
  margin: 0px;
  padding: 0px;
  /* Old browsers */
  display: -webkit-box;
  -webkit-box-orient: vertical;
  -webkit-box-align: stretch;
  display: -moz-box;
  -moz-box-orient: vertical;
  -moz-box-align: stretch;
  display: box;
  box-orient: vertical;
  box-align: stretch;
  /* Modern browsers */
  display: flex;
  flex-direction: column;
  align-items: stretch;
}
div.out_prompt_overlay {
  height: 100%;
  padding: 0px 0.4em;
  position: absolute;
  border-radius: 2px;
}
div.out_prompt_overlay:hover {
  /* use inner shadow to get border that is computed the same on WebKit/FF */
  -webkit-box-shadow: inset 0 0 1px #000;
  box-shadow: inset 0 0 1px #000;
  background: rgba(240, 240, 240, 0.5);
}
div.output_prompt {
  color: #D84315;
}
/* This class is the outer container of all output sections. */
div.output_area {
  padding: 0px;
  page-break-inside: avoid;
  /* Old browsers */
  display: -webkit-box;
  -webkit-box-orient: horizontal;
  -webkit-box-align: stretch;
  display: -moz-box;
  -moz-box-orient: horizontal;
  -moz-box-align: stretch;
  display: box;
  box-orient: horizontal;
  box-align: stretch;
  /* Modern browsers */
  display: flex;
  flex-direction: row;
  align-items: stretch;
}
div.output_area .MathJax_Display {
  text-align: left !important;
}
div.output_area .rendered_html table {
  margin-left: 0;
  margin-right: 0;
}
div.output_area .rendered_html img {
  margin-left: 0;
  margin-right: 0;
}
div.output_area img,
div.output_area svg {
  max-width: 100%;
  height: auto;
}
div.output_area img.unconfined,
div.output_area svg.unconfined {
  max-width: none;
}
/* This is needed to protect the pre formating from global settings such
   as that of bootstrap */
.output {
  /* Old browsers */
  display: -webkit-box;
  -webkit-box-orient: vertical;
  -webkit-box-align: stretch;
  display: -moz-box;
  -moz-box-orient: vertical;
  -moz-box-align: stretch;
  display: box;
  box-orient: vertical;
  box-align: stretch;
  /* Modern browsers */
  display: flex;
  flex-direction: column;
  align-items: stretch;
}
@media (max-width: 540px) {
  div.output_area {
    /* Old browsers */
    display: -webkit-box;
    -webkit-box-orient: vertical;
    -webkit-box-align: stretch;
    display: -moz-box;
    -moz-box-orient: vertical;
    -moz-box-align: stretch;
    display: box;
    box-orient: vertical;
    box-align: stretch;
    /* Modern browsers */
    display: flex;
    flex-direction: column;
    align-items: stretch;
  }
}
div.output_area pre {
  margin: 0;
  padding: 0;
  border: 0;
  vertical-align: baseline;
  color: black;
  background-color: transparent;
  border-radius: 0;
}
/* This class is for the output subarea inside the output_area and after
   the prompt div. */
div.output_subarea {
  overflow-x: auto;
  padding: 0.4em;
  /* Old browsers */
  -webkit-box-flex: 1;
  -moz-box-flex: 1;
  box-flex: 1;
  /* Modern browsers */
  flex: 1;
  max-width: calc(100% - 14ex);
}
div.output_scroll div.output_subarea {
  overflow-x: visible;
}
/* The rest of the output_* classes are for special styling of the different
   output types */
/* all text output has this class: */
div.output_text {
  text-align: left;
  color: #000;
  /* This has to match that of the the CodeMirror class line-height below */
  line-height: 1.21429em;
}
/* stdout/stderr are 'text' as well as 'stream', but execute_result/error are *not* streams */
div.output_stderr {
  background: #fdd;
  /* very light red background for stderr */
}
div.output_latex {
  text-align: left;
}
/* Empty output_javascript divs should have no height */
div.output_javascript:empty {
  padding: 0;
}
.js-error {
  color: darkred;
}
/* raw_input styles */
div.raw_input_container {
  line-height: 1.21429em;
  padding-top: 5px;
}
pre.raw_input_prompt {
  /* nothing needed here. */
}
input.raw_input {
  font-family: monospace;
  font-size: inherit;
  color: inherit;
  width: auto;
  /* make sure input baseline aligns with prompt */
  vertical-align: baseline;
  /* padding + margin = 0.5em between prompt and cursor */
  padding: 0em 0.25em;
  margin: 0em 0.25em;
}
input.raw_input:focus {
  box-shadow: none;
}
p.p-space {
  margin-bottom: 10px;
}
div.output_unrecognized {
  padding: 5px;
  font-weight: bold;
  color: red;
}
div.output_unrecognized a {
  color: inherit;
  text-decoration: none;
}
div.output_unrecognized a:hover {
  color: inherit;
  text-decoration: none;
}
.rendered_html {
  color: #000;
  /* any extras will just be numbers: */
}
.rendered_html em {
  font-style: italic;
}
.rendered_html strong {
  font-weight: bold;
}
.rendered_html u {
  text-decoration: underline;
}
.rendered_html :link {
  text-decoration: underline;
}
.rendered_html :visited {
  text-decoration: underline;
}
.rendered_html h1 {
  font-size: 185.7%;
  margin: 1.08em 0 0 0;
  font-weight: bold;
  line-height: 1.0;
}
.rendered_html h2 {
  font-size: 157.1%;
  margin: 1.27em 0 0 0;
  font-weight: bold;
  line-height: 1.0;
}
.rendered_html h3 {
  font-size: 128.6%;
  margin: 1.55em 0 0 0;
  font-weight: bold;
  line-height: 1.0;
}
.rendered_html h4 {
  font-size: 100%;
  margin: 2em 0 0 0;
  font-weight: bold;
  line-height: 1.0;
}
.rendered_html h5 {
  font-size: 100%;
  margin: 2em 0 0 0;
  font-weight: bold;
  line-height: 1.0;
  font-style: italic;
}
.rendered_html h6 {
  font-size: 100%;
  margin: 2em 0 0 0;
  font-weight: bold;
  line-height: 1.0;
  font-style: italic;
}
.rendered_html h1:first-child {
  margin-top: 0.538em;
}
.rendered_html h2:first-child {
  margin-top: 0.636em;
}
.rendered_html h3:first-child {
  margin-top: 0.777em;
}
.rendered_html h4:first-child {
  margin-top: 1em;
}
.rendered_html h5:first-child {
  margin-top: 1em;
}
.rendered_html h6:first-child {
  margin-top: 1em;
}
.rendered_html ul {
  list-style: disc;
  margin: 0em 2em;
  padding-left: 0px;
}
.rendered_html ul ul {
  list-style: square;
  margin: 0em 2em;
}
.rendered_html ul ul ul {
  list-style: circle;
  margin: 0em 2em;
}
.rendered_html ol {
  list-style: decimal;
  margin: 0em 2em;
  padding-left: 0px;
}
.rendered_html ol ol {
  list-style: upper-alpha;
  margin: 0em 2em;
}
.rendered_html ol ol ol {
  list-style: lower-alpha;
  margin: 0em 2em;
}
.rendered_html ol ol ol ol {
  list-style: lower-roman;
  margin: 0em 2em;
}
.rendered_html ol ol ol ol ol {
  list-style: decimal;
  margin: 0em 2em;
}
.rendered_html * + ul {
  margin-top: 1em;
}
.rendered_html * + ol {
  margin-top: 1em;
}
.rendered_html hr {
  color: black;
  background-color: black;
}
.rendered_html pre {
  margin: 1em 2em;
}
.rendered_html pre,
.rendered_html code {
  border: 0;
  background-color: #fff;
  color: #000;
  font-size: 100%;
  padding: 0px;
}
.rendered_html blockquote {
  margin: 1em 2em;
}
.rendered_html table {
  margin-left: auto;
  margin-right: auto;
  border: 1px solid black;
  border-collapse: collapse;
}
.rendered_html tr,
.rendered_html th,
.rendered_html td {
  border: 1px solid black;
  border-collapse: collapse;
  margin: 1em 2em;
}
.rendered_html td,
.rendered_html th {
  text-align: left;
  vertical-align: middle;
  padding: 4px;
}
.rendered_html th {
  font-weight: bold;
}
.rendered_html * + table {
  margin-top: 1em;
}
.rendered_html p {
  text-align: left;
}
.rendered_html * + p {
  margin-top: 1em;
}
.rendered_html img {
  display: block;
  margin-left: auto;
  margin-right: auto;
}
.rendered_html * + img {
  margin-top: 1em;
}
.rendered_html img,
.rendered_html svg {
  max-width: 100%;
  height: auto;
}
.rendered_html img.unconfined,
.rendered_html svg.unconfined {
  max-width: none;
}
div.text_cell {
  /* Old browsers */
  display: -webkit-box;
  -webkit-box-orient: horizontal;
  -webkit-box-align: stretch;
  display: -moz-box;
  -moz-box-orient: horizontal;
  -moz-box-align: stretch;
  display: box;
  box-orient: horizontal;
  box-align: stretch;
  /* Modern browsers */
  display: flex;
  flex-direction: row;
  align-items: stretch;
}
@media (max-width: 540px) {
  div.text_cell > div.prompt {
    display: none;
  }
}
div.text_cell_render {
  /*font-family: "Helvetica Neue", Arial, Helvetica, Geneva, sans-serif;*/
  outline: none;
  resize: none;
  width: inherit;
  border-style: none;
  padding: 0.5em 0.5em 0.5em 0.4em;
  color: #000;
  box-sizing: border-box;
  -moz-box-sizing: border-box;
  -webkit-box-sizing: border-box;
}
a.anchor-link:link {
  text-decoration: none;
  padding: 0px 20px;
  visibility: hidden;
}
h1:hover .anchor-link,
h2:hover .anchor-link,
h3:hover .anchor-link,
h4:hover .anchor-link,
h5:hover .anchor-link,
h6:hover .anchor-link {
  visibility: visible;
}
.text_cell.rendered .input_area {
  display: none;
}
.text_cell.rendered .rendered_html {
  overflow-x: auto;
  overflow-y: hidden;
}
.text_cell.unrendered .text_cell_render {
  display: none;
}
.cm-header-1,
.cm-header-2,
.cm-header-3,
.cm-header-4,
.cm-header-5,
.cm-header-6 {
  font-weight: bold;
  font-family: "Helvetica Neue", Helvetica, Arial, sans-serif;
}
.cm-header-1 {
  font-size: 185.7%;
}
.cm-header-2 {
  font-size: 157.1%;
}
.cm-header-3 {
  font-size: 128.6%;
}
.cm-header-4 {
  font-size: 110%;
}
.cm-header-5 {
  font-size: 100%;
  font-style: italic;
}
.cm-header-6 {
  font-size: 100%;
  font-style: italic;
}
/*!
*
* IPython notebook webapp
*
*/
@media (max-width: 767px) {
  .notebook_app {
    padding-left: 0px;
    padding-right: 0px;
  }
}
#ipython-main-app {
  box-sizing: border-box;
  -moz-box-sizing: border-box;
  -webkit-box-sizing: border-box;
  height: 100%;
}
div#notebook_panel {
  margin: 0px;
  padding: 0px;
  box-sizing: border-box;
  -moz-box-sizing: border-box;
  -webkit-box-sizing: border-box;
  height: 100%;
}
div#notebook {
  font-size: 14px;
  line-height: 20px;
  overflow-y: hidden;
  overflow-x: auto;
  width: 100%;
  /* This spaces the page away from the edge of the notebook area */
  padding-top: 20px;
  margin: 0px;
  outline: none;
  box-sizing: border-box;
  -moz-box-sizing: border-box;
  -webkit-box-sizing: border-box;
  min-height: 100%;
}
@media not print {
  #notebook-container {
    padding: 15px;
    background-color: #fff;
    min-height: 0;
    -webkit-box-shadow: 0px 0px 12px 1px rgba(87, 87, 87, 0.2);
    box-shadow: 0px 0px 12px 1px rgba(87, 87, 87, 0.2);
  }
}
@media print {
  #notebook-container {
    width: 100%;
  }
}
div.ui-widget-content {
  border: 1px solid #ababab;
  outline: none;
}
pre.dialog {
  background-color: #f7f7f7;
  border: 1px solid #ddd;
  border-radius: 2px;
  padding: 0.4em;
  padding-left: 2em;
}
p.dialog {
  padding: 0.2em;
}
/* Word-wrap output correctly.  This is the CSS3 spelling, though Firefox seems
   to not honor it correctly.  Webkit browsers (Chrome, rekonq, Safari) do.
 */
pre,
code,
kbd,
samp {
  white-space: pre-wrap;
}
#fonttest {
  font-family: monospace;
}
p {
  margin-bottom: 0;
}
.end_space {
  min-height: 100px;
  transition: height .2s ease;
}
.notebook_app > #header {
  -webkit-box-shadow: 0px 0px 12px 1px rgba(87, 87, 87, 0.2);
  box-shadow: 0px 0px 12px 1px rgba(87, 87, 87, 0.2);
}
@media not print {
  .notebook_app {
    background-color: #EEE;
  }
}
kbd {
  border-style: solid;
  border-width: 1px;
  box-shadow: none;
  margin: 2px;
  padding-left: 2px;
  padding-right: 2px;
  padding-top: 1px;
  padding-bottom: 1px;
}
/* CSS for the cell toolbar */
.celltoolbar {
  border: thin solid #CFCFCF;
  border-bottom: none;
  background: #EEE;
  border-radius: 2px 2px 0px 0px;
  width: 100%;
  height: 29px;
  padding-right: 4px;
  /* Old browsers */
  display: -webkit-box;
  -webkit-box-orient: horizontal;
  -webkit-box-align: stretch;
  display: -moz-box;
  -moz-box-orient: horizontal;
  -moz-box-align: stretch;
  display: box;
  box-orient: horizontal;
  box-align: stretch;
  /* Modern browsers */
  display: flex;
  flex-direction: row;
  align-items: stretch;
  /* Old browsers */
  -webkit-box-pack: end;
  -moz-box-pack: end;
  box-pack: end;
  /* Modern browsers */
  justify-content: flex-end;
  display: -webkit-flex;
}
@media print {
  .celltoolbar {
    display: none;
  }
}
.ctb_hideshow {
  display: none;
  vertical-align: bottom;
}
/* ctb_show is added to the ctb_hideshow div to show the cell toolbar.
   Cell toolbars are only shown when the ctb_global_show class is also set.
*/
.ctb_global_show .ctb_show.ctb_hideshow {
  display: block;
}
.ctb_global_show .ctb_show + .input_area,
.ctb_global_show .ctb_show + div.text_cell_input,
.ctb_global_show .ctb_show ~ div.text_cell_render {
  border-top-right-radius: 0px;
  border-top-left-radius: 0px;
}
.ctb_global_show .ctb_show ~ div.text_cell_render {
  border: 1px solid #cfcfcf;
}
.celltoolbar {
  font-size: 87%;
  padding-top: 3px;
}
.celltoolbar select {
  display: block;
  width: 100%;
  height: 32px;
  padding: 6px 12px;
  font-size: 13px;
  line-height: 1.42857143;
  color: #555555;
  background-color: #fff;
  background-image: none;
  border: 1px solid #ccc;
  border-radius: 2px;
  -webkit-box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.075);
  box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.075);
  -webkit-transition: border-color ease-in-out .15s, box-shadow ease-in-out .15s;
  -o-transition: border-color ease-in-out .15s, box-shadow ease-in-out .15s;
  transition: border-color ease-in-out .15s, box-shadow ease-in-out .15s;
  height: 30px;
  padding: 5px 10px;
  font-size: 12px;
  line-height: 1.5;
  border-radius: 1px;
  width: inherit;
  font-size: inherit;
  height: 22px;
  padding: 0px;
  display: inline-block;
}
.celltoolbar select:focus {
  border-color: #66afe9;
  outline: 0;
  -webkit-box-shadow: inset 0 1px 1px rgba(0,0,0,.075), 0 0 8px rgba(102, 175, 233, 0.6);
  box-shadow: inset 0 1px 1px rgba(0,0,0,.075), 0 0 8px rgba(102, 175, 233, 0.6);
}
.celltoolbar select::-moz-placeholder {
  color: #999;
  opacity: 1;
}
.celltoolbar select:-ms-input-placeholder {
  color: #999;
}
.celltoolbar select::-webkit-input-placeholder {
  color: #999;
}
.celltoolbar select::-ms-expand {
  border: 0;
  background-color: transparent;
}
.celltoolbar select[disabled],
.celltoolbar select[readonly],
fieldset[disabled] .celltoolbar select {
  background-color: #eeeeee;
  opacity: 1;
}
.celltoolbar select[disabled],
fieldset[disabled] .celltoolbar select {
  cursor: not-allowed;
}
textarea.celltoolbar select {
  height: auto;
}
select.celltoolbar select {
  height: 30px;
  line-height: 30px;
}
textarea.celltoolbar select,
select[multiple].celltoolbar select {
  height: auto;
}
.celltoolbar label {
  margin-left: 5px;
  margin-right: 5px;
}
.completions {
  position: absolute;
  z-index: 110;
  overflow: hidden;
  border: 1px solid #ababab;
  border-radius: 2px;
  -webkit-box-shadow: 0px 6px 10px -1px #adadad;
  box-shadow: 0px 6px 10px -1px #adadad;
  line-height: 1;
}
.completions select {
  background: white;
  outline: none;
  border: none;
  padding: 0px;
  margin: 0px;
  overflow: auto;
  font-family: monospace;
  font-size: 110%;
  color: #000;
  width: auto;
}
.completions select option.context {
  color: #286090;
}
#kernel_logo_widget {
  float: right !important;
  float: right;
}
#kernel_logo_widget .current_kernel_logo {
  display: none;
  margin-top: -1px;
  margin-bottom: -1px;
  width: 32px;
  height: 32px;
}
#menubar {
  box-sizing: border-box;
  -moz-box-sizing: border-box;
  -webkit-box-sizing: border-box;
  margin-top: 1px;
}
#menubar .navbar {
  border-top: 1px;
  border-radius: 0px 0px 2px 2px;
  margin-bottom: 0px;
}
#menubar .navbar-toggle {
  float: left;
  padding-top: 7px;
  padding-bottom: 7px;
  border: none;
}
#menubar .navbar-collapse {
  clear: left;
}
.nav-wrapper {
  border-bottom: 1px solid #e7e7e7;
}
i.menu-icon {
  padding-top: 4px;
}
ul#help_menu li a {
  overflow: hidden;
  padding-right: 2.2em;
}
ul#help_menu li a i {
  margin-right: -1.2em;
}
.dropdown-submenu {
  position: relative;
}
.dropdown-submenu > .dropdown-menu {
  top: 0;
  left: 100%;
  margin-top: -6px;
  margin-left: -1px;
}
.dropdown-submenu:hover > .dropdown-menu {
  display: block;
}
.dropdown-submenu > a:after {
  display: inline-block;
  font: normal normal normal 14px/1 FontAwesome;
  font-size: inherit;
  text-rendering: auto;
  -webkit-font-smoothing: antialiased;
  -moz-osx-font-smoothing: grayscale;
  display: block;
  content: "\f0da";
  float: right;
  color: #333333;
  margin-top: 2px;
  margin-right: -10px;
}
.dropdown-submenu > a:after.pull-left {
  margin-right: .3em;
}
.dropdown-submenu > a:after.pull-right {
  margin-left: .3em;
}
.dropdown-submenu:hover > a:after {
  color: #262626;
}
.dropdown-submenu.pull-left {
  float: none;
}
.dropdown-submenu.pull-left > .dropdown-menu {
  left: -100%;
  margin-left: 10px;
}
#notification_area {
  float: right !important;
  float: right;
  z-index: 10;
}
.indicator_area {
  float: right !important;
  float: right;
  color: #777;
  margin-left: 5px;
  margin-right: 5px;
  width: 11px;
  z-index: 10;
  text-align: center;
  width: auto;
}
#kernel_indicator {
  float: right !important;
  float: right;
  color: #777;
  margin-left: 5px;
  margin-right: 5px;
  width: 11px;
  z-index: 10;
  text-align: center;
  width: auto;
  border-left: 1px solid;
}
#kernel_indicator .kernel_indicator_name {
  padding-left: 5px;
  padding-right: 5px;
}
#modal_indicator {
  float: right !important;
  float: right;
  color: #777;
  margin-left: 5px;
  margin-right: 5px;
  width: 11px;
  z-index: 10;
  text-align: center;
  width: auto;
}
#readonly-indicator {
  float: right !important;
  float: right;
  color: #777;
  margin-left: 5px;
  margin-right: 5px;
  width: 11px;
  z-index: 10;
  text-align: center;
  width: auto;
  margin-top: 2px;
  margin-bottom: 0px;
  margin-left: 0px;
  margin-right: 0px;
  display: none;
}
.modal_indicator:before {
  width: 1.28571429em;
  text-align: center;
}
.edit_mode .modal_indicator:before {
  display: inline-block;
  font: normal normal normal 14px/1 FontAwesome;
  font-size: inherit;
  text-rendering: auto;
  -webkit-font-smoothing: antialiased;
  -moz-osx-font-smoothing: grayscale;
  content: "\f040";
}
.edit_mode .modal_indicator:before.pull-left {
  margin-right: .3em;
}
.edit_mode .modal_indicator:before.pull-right {
  margin-left: .3em;
}
.command_mode .modal_indicator:before {
  display: inline-block;
  font: normal normal normal 14px/1 FontAwesome;
  font-size: inherit;
  text-rendering: auto;
  -webkit-font-smoothing: antialiased;
  -moz-osx-font-smoothing: grayscale;
  content: ' ';
}
.command_mode .modal_indicator:before.pull-left {
  margin-right: .3em;
}
.command_mode .modal_indicator:before.pull-right {
  margin-left: .3em;
}
.kernel_idle_icon:before {
  display: inline-block;
  font: normal normal normal 14px/1 FontAwesome;
  font-size: inherit;
  text-rendering: auto;
  -webkit-font-smoothing: antialiased;
  -moz-osx-font-smoothing: grayscale;
  content: "\f10c";
}
.kernel_idle_icon:before.pull-left {
  margin-right: .3em;
}
.kernel_idle_icon:before.pull-right {
  margin-left: .3em;
}
.kernel_busy_icon:before {
  display: inline-block;
  font: normal normal normal 14px/1 FontAwesome;
  font-size: inherit;
  text-rendering: auto;
  -webkit-font-smoothing: antialiased;
  -moz-osx-font-smoothing: grayscale;
  content: "\f111";
}
.kernel_busy_icon:before.pull-left {
  margin-right: .3em;
}
.kernel_busy_icon:before.pull-right {
  margin-left: .3em;
}
.kernel_dead_icon:before {
  display: inline-block;
  font: normal normal normal 14px/1 FontAwesome;
  font-size: inherit;
  text-rendering: auto;
  -webkit-font-smoothing: antialiased;
  -moz-osx-font-smoothing: grayscale;
  content: "\f1e2";
}
.kernel_dead_icon:before.pull-left {
  margin-right: .3em;
}
.kernel_dead_icon:before.pull-right {
  margin-left: .3em;
}
.kernel_disconnected_icon:before {
  display: inline-block;
  font: normal normal normal 14px/1 FontAwesome;
  font-size: inherit;
  text-rendering: auto;
  -webkit-font-smoothing: antialiased;
  -moz-osx-font-smoothing: grayscale;
  content: "\f127";
}
.kernel_disconnected_icon:before.pull-left {
  margin-right: .3em;
}
.kernel_disconnected_icon:before.pull-right {
  margin-left: .3em;
}
.notification_widget {
  color: #777;
  z-index: 10;
  background: rgba(240, 240, 240, 0.5);
  margin-right: 4px;
  color: #333;
  background-color: #fff;
  border-color: #ccc;
}
.notification_widget:focus,
.notification_widget.focus {
  color: #333;
  background-color: #e6e6e6;
  border-color: #8c8c8c;
}
.notification_widget:hover {
  color: #333;
  background-color: #e6e6e6;
  border-color: #adadad;
}
.notification_widget:active,
.notification_widget.active,
.open > .dropdown-toggle.notification_widget {
  color: #333;
  background-color: #e6e6e6;
  border-color: #adadad;
}
.notification_widget:active:hover,
.notification_widget.active:hover,
.open > .dropdown-toggle.notification_widget:hover,
.notification_widget:active:focus,
.notification_widget.active:focus,
.open > .dropdown-toggle.notification_widget:focus,
.notification_widget:active.focus,
.notification_widget.active.focus,
.open > .dropdown-toggle.notification_widget.focus {
  color: #333;
  background-color: #d4d4d4;
  border-color: #8c8c8c;
}
.notification_widget:active,
.notification_widget.active,
.open > .dropdown-toggle.notification_widget {
  background-image: none;
}
.notification_widget.disabled:hover,
.notification_widget[disabled]:hover,
fieldset[disabled] .notification_widget:hover,
.notification_widget.disabled:focus,
.notification_widget[disabled]:focus,
fieldset[disabled] .notification_widget:focus,
.notification_widget.disabled.focus,
.notification_widget[disabled].focus,
fieldset[disabled] .notification_widget.focus {
  background-color: #fff;
  border-color: #ccc;
}
.notification_widget .badge {
  color: #fff;
  background-color: #333;
}
.notification_widget.warning {
  color: #fff;
  background-color: #f0ad4e;
  border-color: #eea236;
}
.notification_widget.warning:focus,
.notification_widget.warning.focus {
  color: #fff;
  background-color: #ec971f;
  border-color: #985f0d;
}
.notification_widget.warning:hover {
  color: #fff;
  background-color: #ec971f;
  border-color: #d58512;
}
.notification_widget.warning:active,
.notification_widget.warning.active,
.open > .dropdown-toggle.notification_widget.warning {
  color: #fff;
  background-color: #ec971f;
  border-color: #d58512;
}
.notification_widget.warning:active:hover,
.notification_widget.warning.active:hover,
.open > .dropdown-toggle.notification_widget.warning:hover,
.notification_widget.warning:active:focus,
.notification_widget.warning.active:focus,
.open > .dropdown-toggle.notification_widget.warning:focus,
.notification_widget.warning:active.focus,
.notification_widget.warning.active.focus,
.open > .dropdown-toggle.notification_widget.warning.focus {
  color: #fff;
  background-color: #d58512;
  border-color: #985f0d;
}
.notification_widget.warning:active,
.notification_widget.warning.active,
.open > .dropdown-toggle.notification_widget.warning {
  background-image: none;
}
.notification_widget.warning.disabled:hover,
.notification_widget.warning[disabled]:hover,
fieldset[disabled] .notification_widget.warning:hover,
.notification_widget.warning.disabled:focus,
.notification_widget.warning[disabled]:focus,
fieldset[disabled] .notification_widget.warning:focus,
.notification_widget.warning.disabled.focus,
.notification_widget.warning[disabled].focus,
fieldset[disabled] .notification_widget.warning.focus {
  background-color: #f0ad4e;
  border-color: #eea236;
}
.notification_widget.warning .badge {
  color: #f0ad4e;
  background-color: #fff;
}
.notification_widget.success {
  color: #fff;
  background-color: #5cb85c;
  border-color: #4cae4c;
}
.notification_widget.success:focus,
.notification_widget.success.focus {
  color: #fff;
  background-color: #449d44;
  border-color: #255625;
}
.notification_widget.success:hover {
  color: #fff;
  background-color: #449d44;
  border-color: #398439;
}
.notification_widget.success:active,
.notification_widget.success.active,
.open > .dropdown-toggle.notification_widget.success {
  color: #fff;
  background-color: #449d44;
  border-color: #398439;
}
.notification_widget.success:active:hover,
.notification_widget.success.active:hover,
.open > .dropdown-toggle.notification_widget.success:hover,
.notification_widget.success:active:focus,
.notification_widget.success.active:focus,
.open > .dropdown-toggle.notification_widget.success:focus,
.notification_widget.success:active.focus,
.notification_widget.success.active.focus,
.open > .dropdown-toggle.notification_widget.success.focus {
  color: #fff;
  background-color: #398439;
  border-color: #255625;
}
.notification_widget.success:active,
.notification_widget.success.active,
.open > .dropdown-toggle.notification_widget.success {
  background-image: none;
}
.notification_widget.success.disabled:hover,
.notification_widget.success[disabled]:hover,
fieldset[disabled] .notification_widget.success:hover,
.notification_widget.success.disabled:focus,
.notification_widget.success[disabled]:focus,
fieldset[disabled] .notification_widget.success:focus,
.notification_widget.success.disabled.focus,
.notification_widget.success[disabled].focus,
fieldset[disabled] .notification_widget.success.focus {
  background-color: #5cb85c;
  border-color: #4cae4c;
}
.notification_widget.success .badge {
  color: #5cb85c;
  background-color: #fff;
}
.notification_widget.info {
  color: #fff;
  background-color: #5bc0de;
  border-color: #46b8da;
}
.notification_widget.info:focus,
.notification_widget.info.focus {
  color: #fff;
  background-color: #31b0d5;
  border-color: #1b6d85;
}
.notification_widget.info:hover {
  color: #fff;
  background-color: #31b0d5;
  border-color: #269abc;
}
.notification_widget.info:active,
.notification_widget.info.active,
.open > .dropdown-toggle.notification_widget.info {
  color: #fff;
  background-color: #31b0d5;
  border-color: #269abc;
}
.notification_widget.info:active:hover,
.notification_widget.info.active:hover,
.open > .dropdown-toggle.notification_widget.info:hover,
.notification_widget.info:active:focus,
.notification_widget.info.active:focus,
.open > .dropdown-toggle.notification_widget.info:focus,
.notification_widget.info:active.focus,
.notification_widget.info.active.focus,
.open > .dropdown-toggle.notification_widget.info.focus {
  color: #fff;
  background-color: #269abc;
  border-color: #1b6d85;
}
.notification_widget.info:active,
.notification_widget.info.active,
.open > .dropdown-toggle.notification_widget.info {
  background-image: none;
}
.notification_widget.info.disabled:hover,
.notification_widget.info[disabled]:hover,
fieldset[disabled] .notification_widget.info:hover,
.notification_widget.info.disabled:focus,
.notification_widget.info[disabled]:focus,
fieldset[disabled] .notification_widget.info:focus,
.notification_widget.info.disabled.focus,
.notification_widget.info[disabled].focus,
fieldset[disabled] .notification_widget.info.focus {
  background-color: #5bc0de;
  border-color: #46b8da;
}
.notification_widget.info .badge {
  color: #5bc0de;
  background-color: #fff;
}
.notification_widget.danger {
  color: #fff;
  background-color: #d9534f;
  border-color: #d43f3a;
}
.notification_widget.danger:focus,
.notification_widget.danger.focus {
  color: #fff;
  background-color: #c9302c;
  border-color: #761c19;
}
.notification_widget.danger:hover {
  color: #fff;
  background-color: #c9302c;
  border-color: #ac2925;
}
.notification_widget.danger:active,
.notification_widget.danger.active,
.open > .dropdown-toggle.notification_widget.danger {
  color: #fff;
  background-color: #c9302c;
  border-color: #ac2925;
}
.notification_widget.danger:active:hover,
.notification_widget.danger.active:hover,
.open > .dropdown-toggle.notification_widget.danger:hover,
.notification_widget.danger:active:focus,
.notification_widget.danger.active:focus,
.open > .dropdown-toggle.notification_widget.danger:focus,
.notification_widget.danger:active.focus,
.notification_widget.danger.active.focus,
.open > .dropdown-toggle.notification_widget.danger.focus {
  color: #fff;
  background-color: #ac2925;
  border-color: #761c19;
}
.notification_widget.danger:active,
.notification_widget.danger.active,
.open > .dropdown-toggle.notification_widget.danger {
  background-image: none;
}
.notification_widget.danger.disabled:hover,
.notification_widget.danger[disabled]:hover,
fieldset[disabled] .notification_widget.danger:hover,
.notification_widget.danger.disabled:focus,
.notification_widget.danger[disabled]:focus,
fieldset[disabled] .notification_widget.danger:focus,
.notification_widget.danger.disabled.focus,
.notification_widget.danger[disabled].focus,
fieldset[disabled] .notification_widget.danger.focus {
  background-color: #d9534f;
  border-color: #d43f3a;
}
.notification_widget.danger .badge {
  color: #d9534f;
  background-color: #fff;
}
div#pager {
  background-color: #fff;
  font-size: 14px;
  line-height: 20px;
  overflow: hidden;
  display: none;
  position: fixed;
  bottom: 0px;
  width: 100%;
  max-height: 50%;
  padding-top: 8px;
  -webkit-box-shadow: 0px 0px 12px 1px rgba(87, 87, 87, 0.2);
  box-shadow: 0px 0px 12px 1px rgba(87, 87, 87, 0.2);
  /* Display over codemirror */
  z-index: 100;
  /* Hack which prevents jquery ui resizable from changing top. */
  top: auto !important;
}
div#pager pre {
  line-height: 1.21429em;
  color: #000;
  background-color: #f7f7f7;
  padding: 0.4em;
}
div#pager #pager-button-area {
  position: absolute;
  top: 8px;
  right: 20px;
}
div#pager #pager-contents {
  position: relative;
  overflow: auto;
  width: 100%;
  height: 100%;
}
div#pager #pager-contents #pager-container {
  position: relative;
  padding: 15px 0px;
  box-sizing: border-box;
  -moz-box-sizing: border-box;
  -webkit-box-sizing: border-box;
}
div#pager .ui-resizable-handle {
  top: 0px;
  height: 8px;
  background: #f7f7f7;
  border-top: 1px solid #cfcfcf;
  border-bottom: 1px solid #cfcfcf;
  /* This injects handle bars (a short, wide = symbol) for 
        the resize handle. */
}
div#pager .ui-resizable-handle::after {
  content: '';
  top: 2px;
  left: 50%;
  height: 3px;
  width: 30px;
  margin-left: -15px;
  position: absolute;
  border-top: 1px solid #cfcfcf;
}
.quickhelp {
  /* Old browsers */
  display: -webkit-box;
  -webkit-box-orient: horizontal;
  -webkit-box-align: stretch;
  display: -moz-box;
  -moz-box-orient: horizontal;
  -moz-box-align: stretch;
  display: box;
  box-orient: horizontal;
  box-align: stretch;
  /* Modern browsers */
  display: flex;
  flex-direction: row;
  align-items: stretch;
  line-height: 1.8em;
}
.shortcut_key {
  display: inline-block;
  width: 21ex;
  text-align: right;
  font-family: monospace;
}
.shortcut_descr {
  display: inline-block;
  /* Old browsers */
  -webkit-box-flex: 1;
  -moz-box-flex: 1;
  box-flex: 1;
  /* Modern browsers */
  flex: 1;
}
span.save_widget {
  margin-top: 6px;
}
span.save_widget span.filename {
  height: 1em;
  line-height: 1em;
  padding: 3px;
  margin-left: 16px;
  border: none;
  font-size: 146.5%;
  border-radius: 2px;
}
span.save_widget span.filename:hover {
  background-color: #e6e6e6;
}
span.checkpoint_status,
span.autosave_status {
  font-size: small;
}
@media (max-width: 767px) {
  span.save_widget {
    font-size: small;
  }
  span.checkpoint_status,
  span.autosave_status {
    display: none;
  }
}
@media (min-width: 768px) and (max-width: 991px) {
  span.checkpoint_status {
    display: none;
  }
  span.autosave_status {
    font-size: x-small;
  }
}
.toolbar {
  padding: 0px;
  margin-left: -5px;
  margin-top: 2px;
  margin-bottom: 5px;
  box-sizing: border-box;
  -moz-box-sizing: border-box;
  -webkit-box-sizing: border-box;
}
.toolbar select,
.toolbar label {
  width: auto;
  vertical-align: middle;
  margin-right: 2px;
  margin-bottom: 0px;
  display: inline;
  font-size: 92%;
  margin-left: 0.3em;
  margin-right: 0.3em;
  padding: 0px;
  padding-top: 3px;
}
.toolbar .btn {
  padding: 2px 8px;
}
.toolbar .btn-group {
  margin-top: 0px;
  margin-left: 5px;
}
#maintoolbar {
  margin-bottom: -3px;
  margin-top: -8px;
  border: 0px;
  min-height: 27px;
  margin-left: 0px;
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<div class=" highlight hl-ipython3"><pre><span></span><span class="kn">import</span> <span class="nn">pandas</span> <span class="k">as</span> <span class="nn">pd</span>
<span class="kn">import</span> <span class="nn">numpy</span> <span class="k">as</span> <span class="nn">np</span>
<span class="kn">import</span> <span class="nn">os</span>


<span class="c1">#FC_P=float(input(&quot;Input Fold_Change Threshold&quot;)) #user input fold change parameter</span>
<span class="c1">#PV_P=float(&quot;Input pvalue Threshold&quot;) #user input fold change parameter</span>
<span class="c1">#CV_P=float(&quot;Input CV Thresholds&quot;) #user input fold change parameter</span>
<span class="c1">#Inhibitor=(&quot;Input inhibitor&quot;)  #user input fold change parameter</span>

<span class="k">def</span> <span class="nf">open_file</span><span class="p">(</span><span class="n">filename</span><span class="p">):</span>
    
<span class="c1">#allow for user file input</span>
<span class="c1"># go through each file in the folder</span>
<span class="c1">#for file_name in os.listdir(&quot;.&quot;):</span>
  <span class="c1"># check if it ends with .tsv</span>
    <span class="k">assert</span> <span class="n">filename</span><span class="o">.</span><span class="n">endswith</span><span class="p">(</span><span class="s2">&quot;.tsv&quot;</span><span class="p">)</span>
    <span class="c1"># open the file and process each line</span>
    
    <span class="n">d</span> <span class="o">=</span> <span class="n">pd</span><span class="o">.</span><span class="n">read_csv</span><span class="p">(</span><span class="n">filename</span> <span class="p">,</span><span class="n">usecols</span><span class="o">=</span><span class="nb">list</span><span class="p">(</span><span class="nb">range</span><span class="p">(</span><span class="mi">0</span><span class="p">,</span><span class="mi">7</span><span class="p">)),</span> <span class="n">na_values</span><span class="o">=</span><span class="s1">&#39;inf&#39;</span><span class="p">,</span> <span class="n">sep</span> <span class="o">=</span> <span class="s1">&#39;</span><span class="se">\t</span><span class="s1">&#39;</span><span class="p">)</span>
    <span class="k">return</span> <span class="n">d</span>

<span class="n">d</span><span class="o">=</span><span class="n">open_file</span><span class="p">(</span><span class="s2">&quot;az20.tsv&quot;</span><span class="p">)</span>
<span class="n">d</span>
</pre></div>

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    }

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        vertical-align: top;
    }

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        text-align: right;
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</style>
<table border="1" class="dataframe">
  <thead>
    <tr style="text-align: right;">
      <th></th>
      <th>Substrate</th>
      <th>control_mean</th>
      <th>AZ20_mean</th>
      <th>AZ20_fold_change</th>
      <th>AZ20_p-value</th>
      <th>AZ20_ctrlCV</th>
      <th>AZ20_treatCV</th>
    </tr>
  </thead>
  <tbody>
    <tr>
      <th>0</th>
      <td>1A24_HUMAN(S356)</td>
      <td>1.527934e+07</td>
      <td>2.643439e+07</td>
      <td>1.730074</td>
      <td>0.554298</td>
      <td>1.280092</td>
      <td>0.902944</td>
    </tr>
    <tr>
      <th>1</th>
      <td>1A24_HUMAN(S359)</td>
      <td>1.527934e+07</td>
      <td>2.643439e+07</td>
      <td>1.730074</td>
      <td>0.554298</td>
      <td>1.280092</td>
      <td>0.902944</td>
    </tr>
    <tr>
      <th>2</th>
      <td>1B13_HUMAN(None)</td>
      <td>2.706473e+07</td>
      <td>2.779116e+07</td>
      <td>1.026841</td>
      <td>0.962084</td>
      <td>0.724637</td>
      <td>0.580207</td>
    </tr>
    <tr>
      <th>3</th>
      <td>1B39_HUMAN(M1)</td>
      <td>1.158130e+09</td>
      <td>1.173595e+09</td>
      <td>1.013353</td>
      <td>0.958301</td>
      <td>0.128036</td>
      <td>0.399220</td>
    </tr>
    <tr>
      <th>4</th>
      <td>1B39_HUMAN(M4)</td>
      <td>1.158130e+09</td>
      <td>1.173595e+09</td>
      <td>1.013353</td>
      <td>0.958301</td>
      <td>0.128036</td>
      <td>0.399220</td>
    </tr>
    <tr>
      <th>5</th>
      <td>1B41_HUMAN(None)</td>
      <td>0.000000e+00</td>
      <td>0.000000e+00</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>NaN</td>
    </tr>
    <tr>
      <th>6</th>
      <td>A2M(None)</td>
      <td>1.386130e+09</td>
      <td>2.145604e+09</td>
      <td>1.547909</td>
      <td>0.307816</td>
      <td>0.072912</td>
      <td>0.548219</td>
    </tr>
    <tr>
      <th>7</th>
      <td>AAAS(S495)</td>
      <td>3.886162e+09</td>
      <td>4.023860e+09</td>
      <td>1.035433</td>
      <td>0.798476</td>
      <td>0.118671</td>
      <td>0.190204</td>
    </tr>
    <tr>
      <th>8</th>
      <td>AAGAB(M297)</td>
      <td>1.003738e+07</td>
      <td>5.187831e+06</td>
      <td>0.516851</td>
      <td>0.682755</td>
      <td>1.732051</td>
      <td>1.732051</td>
    </tr>
    <tr>
      <th>9</th>
      <td>AAGAB(S310)</td>
      <td>1.237204e+07</td>
      <td>5.187831e+06</td>
      <td>0.419319</td>
      <td>0.532084</td>
      <td>1.332381</td>
      <td>1.732051</td>
    </tr>
    <tr>
      <th>10</th>
      <td>AAGAB(S311)</td>
      <td>1.398521e+07</td>
      <td>5.187831e+06</td>
      <td>0.370951</td>
      <td>0.427256</td>
      <td>1.106864</td>
      <td>1.732051</td>
    </tr>
    <tr>
      <th>11</th>
      <td>AAK1(S14)</td>
      <td>1.018114e+09</td>
      <td>9.638990e+08</td>
      <td>0.946750</td>
      <td>0.843711</td>
      <td>0.354679</td>
      <td>0.289161</td>
    </tr>
    <tr>
      <th>12</th>
      <td>AAK1(S624)</td>
      <td>2.983340e+07</td>
      <td>1.998685e+08</td>
      <td>6.699488</td>
      <td>0.279794</td>
      <td>1.268167</td>
      <td>1.226010</td>
    </tr>
    <tr>
      <th>13</th>
      <td>AAK1(S637)</td>
      <td>4.201362e+07</td>
      <td>6.203859e+07</td>
      <td>1.476630</td>
      <td>0.000581</td>
      <td>0.107365</td>
      <td>0.043431</td>
    </tr>
    <tr>
      <th>14</th>
      <td>AAK1(T389)</td>
      <td>3.220931e+08</td>
      <td>2.678659e+08</td>
      <td>0.831641</td>
      <td>0.572706</td>
      <td>0.339347</td>
      <td>0.423268</td>
    </tr>
    <tr>
      <th>15</th>
      <td>AAK1(T606)</td>
      <td>1.174191e+09</td>
      <td>1.354491e+09</td>
      <td>1.153553</td>
      <td>0.089500</td>
      <td>0.085950</td>
      <td>0.086223</td>
    </tr>
    <tr>
      <th>16</th>
      <td>AAK1(T620)</td>
      <td>2.983340e+07</td>
      <td>1.998685e+08</td>
      <td>6.699488</td>
      <td>0.279794</td>
      <td>1.268167</td>
      <td>1.226010</td>
    </tr>
    <tr>
      <th>17</th>
      <td>AAK1(T653)</td>
      <td>1.705332e+08</td>
      <td>3.673770e+08</td>
      <td>2.154285</td>
      <td>0.046208</td>
      <td>0.197211</td>
      <td>0.358973</td>
    </tr>
    <tr>
      <th>18</th>
      <td>AARS(None)</td>
      <td>4.608757e+09</td>
      <td>4.305797e+09</td>
      <td>0.934264</td>
      <td>0.341129</td>
      <td>0.061928</td>
      <td>0.097497</td>
    </tr>
    <tr>
      <th>19</th>
      <td>AARS2(S19)</td>
      <td>2.855109e+09</td>
      <td>2.811485e+09</td>
      <td>0.984721</td>
      <td>0.768347</td>
      <td>0.018414</td>
      <td>0.085172</td>
    </tr>
    <tr>
      <th>20</th>
      <td>AATF(M210)</td>
      <td>8.256623e+07</td>
      <td>7.007204e+07</td>
      <td>0.848677</td>
      <td>0.749495</td>
      <td>0.726739</td>
      <td>0.346287</td>
    </tr>
    <tr>
      <th>21</th>
      <td>AATF(None)</td>
      <td>6.009537e+05</td>
      <td>0.000000e+00</td>
      <td>0.000000</td>
      <td>0.355918</td>
      <td>1.732051</td>
      <td>NaN</td>
    </tr>
    <tr>
      <th>22</th>
      <td>AATF(S203)</td>
      <td>2.982143e+09</td>
      <td>3.164170e+09</td>
      <td>1.061039</td>
      <td>0.797772</td>
      <td>0.095957</td>
      <td>0.360818</td>
    </tr>
    <tr>
      <th>23</th>
      <td>AATF(S316)</td>
      <td>7.829675e+06</td>
      <td>0.000000e+00</td>
      <td>0.000000</td>
      <td>0.355918</td>
      <td>1.732051</td>
      <td>NaN</td>
    </tr>
    <tr>
      <th>24</th>
      <td>AATF(S320)</td>
      <td>3.397402e+08</td>
      <td>3.766364e+08</td>
      <td>1.108601</td>
      <td>0.869873</td>
      <td>0.798732</td>
      <td>0.682567</td>
    </tr>
    <tr>
      <th>25</th>
      <td>AATF(S321)</td>
      <td>3.397402e+08</td>
      <td>3.766364e+08</td>
      <td>1.108601</td>
      <td>0.869873</td>
      <td>0.798732</td>
      <td>0.682567</td>
    </tr>
    <tr>
      <th>26</th>
      <td>ABAT(None)</td>
      <td>8.041604e+08</td>
      <td>5.602830e+08</td>
      <td>0.696730</td>
      <td>0.033316</td>
      <td>0.047939</td>
      <td>0.265434</td>
    </tr>
    <tr>
      <th>27</th>
      <td>ABCA13(None)</td>
      <td>1.390026e+08</td>
      <td>1.112417e+08</td>
      <td>0.800285</td>
      <td>0.708723</td>
      <td>0.763185</td>
      <td>0.554518</td>
    </tr>
    <tr>
      <th>28</th>
      <td>ABCA2(S1238)</td>
      <td>6.160821e+07</td>
      <td>1.692898e+08</td>
      <td>2.747845</td>
      <td>0.057258</td>
      <td>0.594418</td>
      <td>0.416502</td>
    </tr>
    <tr>
      <th>29</th>
      <td>ABCA2(S50)</td>
      <td>1.131437e+09</td>
      <td>1.095800e+09</td>
      <td>0.968503</td>
      <td>0.845361</td>
      <td>0.157588</td>
      <td>0.223683</td>
    </tr>
    <tr>
      <th>...</th>
      <td>...</td>
      <td>...</td>
      <td>...</td>
      <td>...</td>
      <td>...</td>
      <td>...</td>
      <td>...</td>
    </tr>
    <tr>
      <th>15495</th>
      <td>ZSCAN10(S107)</td>
      <td>0.000000e+00</td>
      <td>2.351155e+06</td>
      <td>NaN</td>
      <td>0.247851</td>
      <td>NaN</td>
      <td>1.353313</td>
    </tr>
    <tr>
      <th>15496</th>
      <td>ZSCAN10(S153)</td>
      <td>2.180475e+09</td>
      <td>2.604834e+09</td>
      <td>1.194617</td>
      <td>0.256561</td>
      <td>0.229836</td>
      <td>0.116774</td>
    </tr>
    <tr>
      <th>15497</th>
      <td>ZSCAN10(S167)</td>
      <td>0.000000e+00</td>
      <td>0.000000e+00</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>NaN</td>
    </tr>
    <tr>
      <th>15498</th>
      <td>ZSCAN18(S14)</td>
      <td>4.576782e+08</td>
      <td>3.936505e+08</td>
      <td>0.860103</td>
      <td>0.394780</td>
      <td>0.258504</td>
      <td>0.064570</td>
    </tr>
    <tr>
      <th>15499</th>
      <td>ZSCAN2(None)</td>
      <td>3.188879e+08</td>
      <td>2.042961e+08</td>
      <td>0.640652</td>
      <td>0.405436</td>
      <td>0.676480</td>
      <td>0.253560</td>
    </tr>
    <tr>
      <th>15500</th>
      <td>ZSCAN2(S172)</td>
      <td>0.000000e+00</td>
      <td>0.000000e+00</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>NaN</td>
    </tr>
    <tr>
      <th>15501</th>
      <td>ZSCAN25(S300)</td>
      <td>4.711528e+08</td>
      <td>3.314044e+08</td>
      <td>0.703390</td>
      <td>0.391076</td>
      <td>0.390951</td>
      <td>0.561906</td>
    </tr>
    <tr>
      <th>15502</th>
      <td>ZSCAN29(None)</td>
      <td>3.792126e+08</td>
      <td>9.939331e+07</td>
      <td>0.262104</td>
      <td>0.169613</td>
      <td>0.796733</td>
      <td>0.722106</td>
    </tr>
    <tr>
      <th>15503</th>
      <td>ZSCAN29(S153)</td>
      <td>5.370096e+08</td>
      <td>6.947597e+08</td>
      <td>1.293757</td>
      <td>0.504355</td>
      <td>0.699191</td>
      <td>0.121455</td>
    </tr>
    <tr>
      <th>15504</th>
      <td>ZSCAN5B(S295)</td>
      <td>3.612224e+08</td>
      <td>4.354415e+08</td>
      <td>1.205466</td>
      <td>0.458069</td>
      <td>0.285630</td>
      <td>0.287243</td>
    </tr>
    <tr>
      <th>15505</th>
      <td>ZSWIM8(M1141)</td>
      <td>7.269853e+08</td>
      <td>4.446987e+08</td>
      <td>0.611702</td>
      <td>0.043101</td>
      <td>0.156806</td>
      <td>0.345285</td>
    </tr>
    <tr>
      <th>15506</th>
      <td>ZSWIM8(S1130)</td>
      <td>1.488450e+09</td>
      <td>1.913775e+09</td>
      <td>1.285750</td>
      <td>0.231530</td>
      <td>0.127233</td>
      <td>0.271753</td>
    </tr>
    <tr>
      <th>15507</th>
      <td>ZSWIM8(S1156)</td>
      <td>7.269853e+08</td>
      <td>4.446987e+08</td>
      <td>0.611702</td>
      <td>0.043101</td>
      <td>0.156806</td>
      <td>0.345285</td>
    </tr>
    <tr>
      <th>15508</th>
      <td>ZSWIM8(S53)</td>
      <td>5.309431e+09</td>
      <td>1.281393e+09</td>
      <td>0.241343</td>
      <td>0.016031</td>
      <td>0.277708</td>
      <td>1.169449</td>
    </tr>
    <tr>
      <th>15509</th>
      <td>ZXDC(S34)</td>
      <td>1.912293e+08</td>
      <td>6.674125e+08</td>
      <td>3.490117</td>
      <td>0.016954</td>
      <td>1.015217</td>
      <td>0.240578</td>
    </tr>
    <tr>
      <th>15510</th>
      <td>ZXDC(T172)</td>
      <td>1.972413e+09</td>
      <td>1.980187e+09</td>
      <td>1.003941</td>
      <td>0.966234</td>
      <td>0.147249</td>
      <td>0.047197</td>
    </tr>
    <tr>
      <th>15511</th>
      <td>ZYX(S170)</td>
      <td>1.669565e+08</td>
      <td>4.415860e+08</td>
      <td>2.644917</td>
      <td>0.073650</td>
      <td>0.251771</td>
      <td>0.488547</td>
    </tr>
    <tr>
      <th>15512</th>
      <td>ZYX(S259)</td>
      <td>7.287603e+08</td>
      <td>1.035166e+09</td>
      <td>1.420448</td>
      <td>0.035542</td>
      <td>0.203295</td>
      <td>0.124711</td>
    </tr>
    <tr>
      <th>15513</th>
      <td>ZYX(S267)</td>
      <td>4.149174e+09</td>
      <td>5.659259e+09</td>
      <td>1.363948</td>
      <td>0.664736</td>
      <td>0.780284</td>
      <td>0.837862</td>
    </tr>
    <tr>
      <th>15514</th>
      <td>ZYX(S281)</td>
      <td>2.967725e+09</td>
      <td>3.839036e+09</td>
      <td>1.293595</td>
      <td>0.142228</td>
      <td>0.262709</td>
      <td>0.113765</td>
    </tr>
    <tr>
      <th>15515</th>
      <td>ZYX(S308)</td>
      <td>1.591670e+09</td>
      <td>1.325098e+09</td>
      <td>0.832521</td>
      <td>0.224035</td>
      <td>0.098778</td>
      <td>0.228019</td>
    </tr>
    <tr>
      <th>15516</th>
      <td>ZYX(S344)</td>
      <td>1.858139e+10</td>
      <td>2.262601e+10</td>
      <td>1.217670</td>
      <td>0.059541</td>
      <td>0.080557</td>
      <td>0.115980</td>
    </tr>
    <tr>
      <th>15517</th>
      <td>ZYX(T270)</td>
      <td>1.794139e+08</td>
      <td>3.340900e+08</td>
      <td>1.862118</td>
      <td>0.146616</td>
      <td>0.687707</td>
      <td>0.308358</td>
    </tr>
    <tr>
      <th>15518</th>
      <td>ZYX(T274)</td>
      <td>4.364455e+07</td>
      <td>5.227431e+07</td>
      <td>1.197728</td>
      <td>0.599593</td>
      <td>0.606458</td>
      <td>0.099992</td>
    </tr>
    <tr>
      <th>15519</th>
      <td>ZZEF1(S1464)</td>
      <td>5.725008e+07</td>
      <td>5.304806e+07</td>
      <td>0.926602</td>
      <td>0.927833</td>
      <td>0.913163</td>
      <td>1.067354</td>
    </tr>
    <tr>
      <th>15520</th>
      <td>ZZZ3(S113)</td>
      <td>1.313713e+08</td>
      <td>9.847906e+07</td>
      <td>0.749624</td>
      <td>0.315054</td>
      <td>0.362038</td>
      <td>0.212820</td>
    </tr>
    <tr>
      <th>15521</th>
      <td>ZZZ3(S314)</td>
      <td>0.000000e+00</td>
      <td>0.000000e+00</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>NaN</td>
    </tr>
    <tr>
      <th>15522</th>
      <td>ZZZ3(S777)</td>
      <td>0.000000e+00</td>
      <td>0.000000e+00</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>NaN</td>
    </tr>
    <tr>
      <th>15523</th>
      <td>ZZZ3(S82)</td>
      <td>2.989399e+08</td>
      <td>2.667268e+08</td>
      <td>0.892242</td>
      <td>0.485882</td>
      <td>0.206880</td>
      <td>0.160096</td>
    </tr>
    <tr>
      <th>15524</th>
      <td>ZZZ3(Y399)</td>
      <td>0.000000e+00</td>
      <td>0.000000e+00</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>NaN</td>
    </tr>
  </tbody>
</table>
<p>15525 rows × 7 columns</p>
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<div class=" highlight hl-ipython3"><pre><span></span><span class="n">d_cols</span><span class="o">=</span><span class="p">[</span><span class="s2">&quot;Substrate&quot;</span><span class="p">,</span> <span class="s2">&quot;Control_mean&quot;</span><span class="p">,</span> <span class="s2">&quot;Inhibitor_mean&quot;</span><span class="p">,</span> <span class="s2">&quot;Fold_change&quot;</span><span class="p">,</span> <span class="s2">&quot;p_value&quot;</span><span class="p">,</span> <span class="s2">&quot;ctrlCV&quot;</span><span class="p">,</span> <span class="s2">&quot;treatCV&quot;</span> <span class="p">]</span>
<span class="n">d</span><span class="o">.</span><span class="n">columns</span><span class="o">=</span><span class="n">d_cols</span>

<span class="n">d</span><span class="o">.</span><span class="n">head</span><span class="p">()</span>
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<table border="1" class="dataframe">
  <thead>
    <tr style="text-align: right;">
      <th></th>
      <th>Substrate</th>
      <th>Control_mean</th>
      <th>Inhibitor_mean</th>
      <th>Fold_change</th>
      <th>p_value</th>
      <th>ctrlCV</th>
      <th>treatCV</th>
    </tr>
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    <tr>
      <th>0</th>
      <td>1A24_HUMAN(S356)</td>
      <td>1.527934e+07</td>
      <td>2.643439e+07</td>
      <td>1.730074</td>
      <td>0.554298</td>
      <td>1.280092</td>
      <td>0.902944</td>
    </tr>
    <tr>
      <th>1</th>
      <td>1A24_HUMAN(S359)</td>
      <td>1.527934e+07</td>
      <td>2.643439e+07</td>
      <td>1.730074</td>
      <td>0.554298</td>
      <td>1.280092</td>
      <td>0.902944</td>
    </tr>
    <tr>
      <th>2</th>
      <td>1B13_HUMAN(None)</td>
      <td>2.706473e+07</td>
      <td>2.779116e+07</td>
      <td>1.026841</td>
      <td>0.962084</td>
      <td>0.724637</td>
      <td>0.580207</td>
    </tr>
    <tr>
      <th>3</th>
      <td>1B39_HUMAN(M1)</td>
      <td>1.158130e+09</td>
      <td>1.173595e+09</td>
      <td>1.013353</td>
      <td>0.958301</td>
      <td>0.128036</td>
      <td>0.399220</td>
    </tr>
    <tr>
      <th>4</th>
      <td>1B39_HUMAN(M4)</td>
      <td>1.158130e+09</td>
      <td>1.173595e+09</td>
      <td>1.013353</td>
      <td>0.958301</td>
      <td>0.128036</td>
      <td>0.399220</td>
    </tr>
  </tbody>
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<div class=" highlight hl-ipython3"><pre><span></span><span class="c1">####drop out methonine and none####</span>

<span class="kn">import</span> <span class="nn">re</span>


<span class="n">d</span><span class="o">=</span><span class="p">(</span><span class="n">d</span><span class="p">[</span><span class="o">~</span><span class="n">d</span><span class="o">.</span><span class="n">Substrate</span><span class="o">.</span><span class="n">str</span><span class="o">.</span><span class="n">contains</span><span class="p">(</span><span class="s2">&quot;None&quot;</span><span class="p">)]</span> <span class="p">)</span> <span class="c1">#drop rows with &quot;None&quot;</span>

<span class="n">patternDel</span> <span class="o">=</span> <span class="sa">r</span><span class="s2">&quot;\([M]\d+\)&quot;</span> <span class="c1">#Use Regex to find &quot;(M and any number of digits)&quot; #\d+ : one or more digits)</span>

<span class="n">dd</span><span class="o">=</span><span class="p">(</span><span class="n">d</span><span class="p">[</span><span class="o">~</span><span class="n">d</span><span class="o">.</span><span class="n">Substrate</span><span class="o">.</span><span class="n">str</span><span class="o">.</span><span class="n">contains</span><span class="p">(</span><span class="n">patternDel</span><span class="p">)]</span><span class="o">.</span><span class="n">copy</span><span class="p">())</span> <span class="c1">#d1: rows with (Mddd) removed....copy() to remove conflict</span>

<span class="nb">print</span><span class="p">(</span><span class="n">dd</span><span class="o">.</span><span class="n">head</span><span class="p">(</span><span class="mi">30</span><span class="p">))</span>
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<pre>           Substrate  Control_mean  Inhibitor_mean  Fold_change   p_value  \
0   1A24_HUMAN(S356)  1.527934e+07    2.643439e+07     1.730074  0.554298   
1   1A24_HUMAN(S359)  1.527934e+07    2.643439e+07     1.730074  0.554298   
7         AAAS(S495)  3.886162e+09    4.023860e+09     1.035433  0.798476   
9        AAGAB(S310)  1.237204e+07    5.187831e+06     0.419319  0.532084   
10       AAGAB(S311)  1.398521e+07    5.187831e+06     0.370951  0.427256   
11         AAK1(S14)  1.018114e+09    9.638990e+08     0.946750  0.843711   
12        AAK1(S624)  2.983340e+07    1.998685e+08     6.699488  0.279794   
13        AAK1(S637)  4.201362e+07    6.203859e+07     1.476630  0.000581   
14        AAK1(T389)  3.220931e+08    2.678659e+08     0.831641  0.572706   
15        AAK1(T606)  1.174191e+09    1.354491e+09     1.153553  0.089500   
16        AAK1(T620)  2.983340e+07    1.998685e+08     6.699488  0.279794   
17        AAK1(T653)  1.705332e+08    3.673770e+08     2.154285  0.046208   
19        AARS2(S19)  2.855109e+09    2.811485e+09     0.984721  0.768347   
22        AATF(S203)  2.982143e+09    3.164170e+09     1.061039  0.797772   
23        AATF(S316)  7.829675e+06    0.000000e+00     0.000000  0.355918   
24        AATF(S320)  3.397402e+08    3.766364e+08     1.108601  0.869873   
25        AATF(S321)  3.397402e+08    3.766364e+08     1.108601  0.869873   
28      ABCA2(S1238)  6.160821e+07    1.692898e+08     2.747845  0.057258   
29        ABCA2(S50)  1.131437e+09    1.095800e+09     0.968503  0.845361   
31      ABCA6(S1238)  8.738656e+08    7.933750e+08     0.907891  0.831493   
33       ABCC1(S916)  7.742271e+07    2.377071e+07     0.307025  0.150657   
34       ABCC5(S509)  1.015387e+08    7.360427e+07     0.724889  0.565325   
35       ABCF1(S105)  3.411235e+09    5.577619e+09     1.635073  0.020592   
36       ABCF1(S109)  3.729907e+09    5.887469e+09     1.578449  0.024749   
37       ABCF1(S140)  5.130510e+09    3.859859e+09     0.752334  0.171288   
38        ABCF1(S22)  2.839707e+09    2.980491e+09     1.049577  0.744598   
39       ABCF1(S228)  1.332710e+09    1.672667e+09     1.255087  0.161703   
40       ABCF1(T108)  3.729907e+09    5.887469e+09     1.578449  0.024749   
42      ABHD15(S434)  0.000000e+00    1.154521e+06          NaN  0.355918   
44        ABI1(S183)  6.954255e+09    8.002003e+09     1.150663  0.274058   

      ctrlCV   treatCV  
0   1.280092  0.902944  
1   1.280092  0.902944  
7   0.118671  0.190204  
9   1.332381  1.732051  
10  1.106864  1.732051  
11  0.354679  0.289161  
12  1.268167  1.226010  
13  0.107365  0.043431  
14  0.339347  0.423268  
15  0.085950  0.086223  
16  1.268167  1.226010  
17  0.197211  0.358973  
19  0.018414  0.085172  
22  0.095957  0.360818  
23  1.732051       NaN  
24  0.798732  0.682567  
25  0.798732  0.682567  
28  0.594418  0.416502  
29  0.157588  0.223683  
31  0.499366  0.567992  
33  0.657446  1.024066  
34  0.488059  0.845384  
35  0.176285  0.186755  
36  0.184789  0.178244  
37  0.209021  0.239829  
38  0.238516  0.076551  
39  0.226222  0.127241  
40  0.184789  0.178244  
42       NaN  1.732051  
44  0.131522  0.149789  
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<div class=" highlight hl-ipython3"><pre><span></span><span class="c1">#add split of gene/protein names to XXX_HUMAN   and (SNNN)</span>

<span class="n">dd</span><span class="p">[[</span><span class="s2">&quot;Substrate&quot;</span><span class="p">,</span><span class="s2">&quot;Phosphosite&quot;</span><span class="p">]]</span> <span class="o">=</span> <span class="n">dd</span><span class="o">.</span><span class="n">Substrate</span><span class="o">.</span><span class="n">str</span><span class="o">.</span><span class="n">extract</span><span class="p">(</span><span class="sa">r</span><span class="s2">&quot;(.+)\((.\d+)&quot;</span><span class="p">,</span> <span class="n">expand</span><span class="o">=</span><span class="kc">True</span><span class="p">)</span>
<span class="c1">#</span>
<span class="nb">print</span> <span class="p">(</span><span class="n">dd</span><span class="o">.</span><span class="n">head</span><span class="p">(</span><span class="mi">30</span><span class="p">))</span>
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<pre>     Substrate  Control_mean  Inhibitor_mean  Fold_change   p_value    ctrlCV  \
0   1A24_HUMAN  1.527934e+07    2.643439e+07     1.730074  0.554298  1.280092   
1   1A24_HUMAN  1.527934e+07    2.643439e+07     1.730074  0.554298  1.280092   
7         AAAS  3.886162e+09    4.023860e+09     1.035433  0.798476  0.118671   
9        AAGAB  1.237204e+07    5.187831e+06     0.419319  0.532084  1.332381   
10       AAGAB  1.398521e+07    5.187831e+06     0.370951  0.427256  1.106864   
11        AAK1  1.018114e+09    9.638990e+08     0.946750  0.843711  0.354679   
12        AAK1  2.983340e+07    1.998685e+08     6.699488  0.279794  1.268167   
13        AAK1  4.201362e+07    6.203859e+07     1.476630  0.000581  0.107365   
14        AAK1  3.220931e+08    2.678659e+08     0.831641  0.572706  0.339347   
15        AAK1  1.174191e+09    1.354491e+09     1.153553  0.089500  0.085950   
16        AAK1  2.983340e+07    1.998685e+08     6.699488  0.279794  1.268167   
17        AAK1  1.705332e+08    3.673770e+08     2.154285  0.046208  0.197211   
19       AARS2  2.855109e+09    2.811485e+09     0.984721  0.768347  0.018414   
22        AATF  2.982143e+09    3.164170e+09     1.061039  0.797772  0.095957   
23        AATF  7.829675e+06    0.000000e+00     0.000000  0.355918  1.732051   
24        AATF  3.397402e+08    3.766364e+08     1.108601  0.869873  0.798732   
25        AATF  3.397402e+08    3.766364e+08     1.108601  0.869873  0.798732   
28       ABCA2  6.160821e+07    1.692898e+08     2.747845  0.057258  0.594418   
29       ABCA2  1.131437e+09    1.095800e+09     0.968503  0.845361  0.157588   
31       ABCA6  8.738656e+08    7.933750e+08     0.907891  0.831493  0.499366   
33       ABCC1  7.742271e+07    2.377071e+07     0.307025  0.150657  0.657446   
34       ABCC5  1.015387e+08    7.360427e+07     0.724889  0.565325  0.488059   
35       ABCF1  3.411235e+09    5.577619e+09     1.635073  0.020592  0.176285   
36       ABCF1  3.729907e+09    5.887469e+09     1.578449  0.024749  0.184789   
37       ABCF1  5.130510e+09    3.859859e+09     0.752334  0.171288  0.209021   
38       ABCF1  2.839707e+09    2.980491e+09     1.049577  0.744598  0.238516   
39       ABCF1  1.332710e+09    1.672667e+09     1.255087  0.161703  0.226222   
40       ABCF1  3.729907e+09    5.887469e+09     1.578449  0.024749  0.184789   
42      ABHD15  0.000000e+00    1.154521e+06          NaN  0.355918       NaN   
44        ABI1  6.954255e+09    8.002003e+09     1.150663  0.274058  0.131522   

     treatCV Phosphosite  
0   0.902944        S356  
1   0.902944        S359  
7   0.190204        S495  
9   1.732051        S310  
10  1.732051        S311  
11  0.289161         S14  
12  1.226010        S624  
13  0.043431        S637  
14  0.423268        T389  
15  0.086223        T606  
16  1.226010        T620  
17  0.358973        T653  
19  0.085172         S19  
22  0.360818        S203  
23       NaN        S316  
24  0.682567        S320  
25  0.682567        S321  
28  0.416502       S1238  
29  0.223683         S50  
31  0.567992       S1238  
33  1.024066        S916  
34  0.845384        S509  
35  0.186755        S105  
36  0.178244        S109  
37  0.239829        S140  
38  0.076551         S22  
39  0.127241        S228  
40  0.178244        T108  
42  1.732051        S434  
44  0.149789        S183  
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<div class=" highlight hl-ipython3"><pre><span></span><span class="c1">#https://www.uniprot.org/uniprot/?query=DPOLZ_HUMAN&amp;fil=reviewed%3Ayes&amp;columns=genes(PREFERRED)&amp;format=tab</span>
<span class="c1">#https://www.uniprot.org/uniprot/?query=DUS27_HUMAN&amp;columns=genes(PREFERRED)&amp;format=tab</span>
<span class="kn">import</span> <span class="nn">re</span>
<span class="kn">import</span> <span class="nn">requests</span>

<span class="c1">#Function: Substrates with &quot;_HUMAN&quot; converted to Uniprot Gene Names</span>
<span class="k">def</span> <span class="nf">process_query</span><span class="p">(</span><span class="n">query</span><span class="p">):</span>
    
    <span class="k">if</span> <span class="n">re</span><span class="o">.</span><span class="n">match</span><span class="p">(</span><span class="sa">r</span><span class="s2">&quot;.+_HUMAN&quot;</span><span class="p">,</span> <span class="n">query</span><span class="p">):</span>
        <span class="n">URL</span> <span class="o">=</span> <span class="s1">&#39;http://www.uniprot.org/uniprot/?query=&#39;</span> <span class="o">+</span> <span class="n">query</span> <span class="o">+</span> <span class="s1">&#39;&amp;columns=genes(PREFERRED)&amp;format=tab&#39;</span>
        <span class="n">r</span> <span class="o">=</span> <span class="n">requests</span><span class="o">.</span><span class="n">get</span><span class="p">(</span><span class="n">URL</span><span class="p">)</span>
        <span class="n">lines</span> <span class="o">=</span> <span class="n">r</span><span class="o">.</span><span class="n">text</span><span class="o">.</span><span class="n">split</span><span class="p">(</span><span class="s2">&quot;</span><span class="se">\n</span><span class="s2">&quot;</span><span class="p">)</span>
        <span class="n">gene_name</span><span class="o">=</span><span class="n">lines</span><span class="p">[</span><span class="mi">1</span><span class="p">:</span><span class="mi">2</span><span class="p">]</span>        <span class="c1">#return top preferred uniprot gene result #get accession number</span>
        
        <span class="k">return</span> <span class="nb">str</span><span class="p">(</span><span class="n">gene_name</span><span class="p">)</span>  <span class="c1">#return gene as string instead of string within a list [&quot;&quot;] #get accession number</span>
    <span class="k">else</span><span class="p">:</span>
        <span class="k">return</span> <span class="n">query</span>
    
<span class="n">process_query</span><span class="p">(</span><span class="s2">&quot;ADT1_HUMAN&quot;</span><span class="p">)</span> <span class="c1">#Test</span>
    
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<pre>&#34;[&#39;SLC25A4&#39;]&#34;</pre>
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<div class=" highlight hl-ipython3"><pre><span></span><span class="c1">#make copy of Substrate to Substrate gene</span>

<span class="n">dd</span><span class="p">[</span><span class="s2">&quot;Sub_gene&quot;</span><span class="p">]</span><span class="o">=</span><span class="n">dd</span><span class="p">[</span><span class="s2">&quot;Substrate&quot;</span><span class="p">]</span><span class="o">.</span><span class="n">copy</span><span class="p">()</span>
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<div class=" highlight hl-ipython3"><pre><span></span><span class="c1">#Substrates with &quot;_HUMAN&quot; converted to Uniprot Gene Names</span>

<span class="n">dd</span><span class="o">.</span><span class="n">Sub_gene</span> <span class="o">=</span> <span class="n">dd</span><span class="o">.</span><span class="n">apply</span><span class="p">(</span><span class="k">lambda</span> <span class="n">row</span><span class="p">:</span> <span class="n">process_query</span><span class="p">(</span><span class="n">row</span><span class="p">[</span><span class="s2">&quot;Substrate&quot;</span><span class="p">]),</span> <span class="n">axis</span> <span class="o">=</span><span class="mi">1</span><span class="p">)</span>

<span class="n">dd</span><span class="p">[</span><span class="s2">&quot;Sub_gene&quot;</span><span class="p">]</span> <span class="o">=</span> <span class="n">dd</span><span class="p">[</span><span class="s2">&quot;Sub_gene&quot;</span><span class="p">]</span><span class="o">.</span><span class="n">str</span><span class="o">.</span><span class="n">strip</span><span class="p">(</span><span class="s2">&quot;[]&quot;</span><span class="p">)</span><span class="o">.</span><span class="n">str</span><span class="o">.</span><span class="n">strip</span><span class="p">(</span><span class="s2">&quot;&#39;&#39;&quot;</span><span class="p">)</span>  <span class="c1">#remove square bracket and &#39;&#39; </span>
  <span class="c1">#remove square bracket and &#39;&#39; </span>

<span class="nb">print</span><span class="p">(</span><span class="n">dd</span><span class="o">.</span><span class="n">head</span><span class="p">(</span><span class="mi">5</span><span class="p">))</span> <span class="c1">#Test</span>
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<pre>     Substrate  Control_mean  Inhibitor_mean  Fold_change   p_value    ctrlCV  \
0   1A24_HUMAN  1.527934e+07    2.643439e+07     1.730074  0.554298  1.280092   
1   1A24_HUMAN  1.527934e+07    2.643439e+07     1.730074  0.554298  1.280092   
7         AAAS  3.886162e+09    4.023860e+09     1.035433  0.798476  0.118671   
9        AAGAB  1.237204e+07    5.187831e+06     0.419319  0.532084  1.332381   
10       AAGAB  1.398521e+07    5.187831e+06     0.370951  0.427256  1.106864   

     treatCV Phosphosite Sub_gene  
0   0.902944        S356    HLA-A  
1   0.902944        S359    HLA-A  
7   0.190204        S495     AAAS  
9   1.732051        S310    AAGAB  
10  1.732051        S311    AAGAB  
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<div class=" highlight hl-ipython3"><pre><span></span><span class="c1"># </span>
<span class="c1"># dd.to_csv(&quot;checkH.csv&quot;)</span>
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<div class=" highlight hl-ipython3"><pre><span></span><span class="c1">#Removes Substrates &quot;_HUMAN&quot; with no Sub_gene result: likely experimental protein</span>
<span class="n">dd</span><span class="o">.</span><span class="n">Sub_gene</span><span class="o">.</span><span class="n">replace</span><span class="p">(</span><span class="s2">&quot; &quot;</span><span class="p">,</span> <span class="n">np</span><span class="o">.</span><span class="n">nan</span><span class="p">,</span> <span class="n">inplace</span><span class="o">=</span><span class="kc">True</span><span class="p">)</span>
<span class="n">dd</span><span class="o">.</span><span class="n">dropna</span><span class="p">(</span><span class="n">subset</span><span class="o">=</span><span class="p">[</span><span class="s2">&quot;Sub_gene&quot;</span><span class="p">],</span> <span class="n">inplace</span><span class="o">=</span><span class="kc">True</span><span class="p">)</span>
<span class="c1">#dd.to_csv(&quot;checkNoH.csv&quot;)</span>
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<div class=" highlight hl-ipython3"><pre><span></span><span class="c1">#make Kinase column, match Gene to Phosphosite to Kinase info from Kinase_substrate.csv</span>
<span class="k">class</span> <span class="nc">KinaseSearcher</span><span class="p">:</span>
    <span class="k">def</span> <span class="nf">__init__</span><span class="p">(</span><span class="bp">self</span><span class="p">,</span><span class="n">filename</span><span class="p">):</span>
        <span class="bp">self</span><span class="o">.</span><span class="n">filename</span><span class="o">=</span><span class="n">filename</span>
        <span class="bp">self</span><span class="o">.</span><span class="n">open</span><span class="p">()</span>
        
    <span class="k">def</span> <span class="nf">open</span><span class="p">(</span><span class="bp">self</span><span class="p">):</span>
        <span class="bp">self</span><span class="o">.</span><span class="n">data</span><span class="o">=</span><span class="n">pd</span><span class="o">.</span><span class="n">read_csv</span><span class="p">(</span><span class="bp">self</span><span class="o">.</span><span class="n">filename</span><span class="p">,</span> <span class="n">header</span><span class="o">=</span><span class="mi">0</span><span class="p">)</span>
        
    <span class="k">def</span> <span class="nf">findkinase</span><span class="p">(</span><span class="bp">self</span><span class="p">,</span><span class="n">sub_gene</span><span class="p">,</span> <span class="n">sub_mod_rsd</span><span class="p">):</span>
        <span class="n">a</span> <span class="o">=</span> <span class="bp">self</span><span class="o">.</span><span class="n">data</span><span class="p">[</span><span class="bp">self</span><span class="o">.</span><span class="n">data</span><span class="o">.</span><span class="n">SUB_GENE</span><span class="o">.</span><span class="n">str</span><span class="o">.</span><span class="n">contains</span><span class="p">(</span><span class="n">sub_gene</span><span class="p">)</span><span class="o">==</span><span class="kc">True</span><span class="p">]</span>
        <span class="n">b</span> <span class="o">=</span> <span class="n">a</span><span class="p">[</span><span class="n">a</span><span class="o">.</span><span class="n">SUB_MOD_RSD</span><span class="o">.</span><span class="n">str</span><span class="o">.</span><span class="n">contains</span><span class="p">(</span><span class="n">sub_mod_rsd</span><span class="p">)</span><span class="o">==</span><span class="kc">True</span><span class="p">]</span>
        <span class="k">if</span> <span class="nb">len</span><span class="p">(</span><span class="n">b</span><span class="o">.</span><span class="n">index</span><span class="p">)</span><span class="o">==</span> <span class="mi">0</span><span class="p">:</span>
            <span class="k">return</span> <span class="kc">None</span>
        <span class="k">else</span><span class="p">:</span>
            <span class="k">return</span> <span class="s2">&quot;,&quot;</span><span class="o">.</span><span class="n">join</span><span class="p">(</span><span class="n">b</span><span class="p">[</span><span class="s2">&quot;KINASE&quot;</span><span class="p">])</span> 
        
        <span class="c1">#just the kinase, if not it will return all columns from kinase_substrate</span>
    <span class="c1">#and self.data.SUB_MOD_RSD.str.contains(sub_mod_rsd)]</span>
        
<span class="n">k</span><span class="o">=</span><span class="n">KinaseSearcher</span><span class="p">(</span><span class="s2">&quot;kinase_substrate.csv&quot;</span><span class="p">)</span>    
<span class="n">k</span><span class="o">.</span><span class="n">findkinase</span><span class="p">(</span><span class="s2">&quot;AKT1&quot;</span><span class="p">,</span> <span class="s2">&quot;S129&quot;</span><span class="p">)</span>     <span class="c1">#Run Test: AKT1(S129)</span>
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<pre>&#39;CK2A1&#39;</pre>
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<div class=" highlight hl-ipython3"><pre><span></span><span class="c1"># class KinaseSearcher:</span>
<span class="c1">#     def __init__(self,filename):</span>
<span class="c1">#         self.filename=filename</span>
<span class="c1">#         self.open()</span>
        
<span class="c1">#     def open(self):</span>
<span class="c1">#         self.data=pd.read_csv(self.filename, header=0)</span>
        
<span class="c1">#     def findkinase(self,sub_gene, phosphosite):</span>
<span class="c1">#         a = self.data[self.data.SUB_GENE.str.contains(sub_gene)==True]</span>
<span class="c1">#         #return a</span>
<span class="c1">#         #b = a[&quot;Z_SITE_{}&quot;.format(i)].str.contains(phosphosite)</span>
<span class="c1">#         for i in range(1,49,1):</span>
<span class="c1">#             b = a[a[&quot;Z_SITE_{}&quot;.format(i)].str.contains(phosphosite)==True]</span>
<span class="c1">#             return b</span>
<span class="c1">#             if len(b)== 0:</span>
<span class="c1">#                 return None</span>
<span class="c1">#             else:</span>
<span class="c1">#                 b==phosphosite</span>
<span class="c1">#                 return a[&quot;KINASE&quot;]</span>
<span class="c1">#                 #return b[&quot;KINASE&quot;]</span>
        
<span class="c1">#         #just the kinase, if not it will return all columns from kinase_substrate</span>
<span class="c1">#         #and self.data.SUB_MOD_RSD.str.contains(sub_mod_rsd)]</span>
        
<span class="c1"># k=KinaseSearcher(&quot;kinase_substrate_filtered.csv&quot;)    #kinase_substrated_filtered runs up to z_site_48</span>
<span class="c1"># k.findkinase(&quot;NCF1&quot;, &quot;S303&quot;)     #Run Test: AKT1(S129)</span>
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<div class=" highlight hl-ipython3"><pre><span></span><span class="c1">#to apply class and populate column for kinase GENE name</span>
<span class="n">dk</span><span class="o">=</span><span class="n">dd</span><span class="o">.</span><span class="n">apply</span><span class="p">(</span><span class="k">lambda</span> <span class="n">row</span><span class="p">:</span> <span class="n">k</span><span class="o">.</span><span class="n">findkinase</span><span class="p">(</span><span class="n">row</span><span class="p">[</span><span class="s2">&quot;Sub_gene&quot;</span><span class="p">],</span><span class="n">row</span><span class="p">[</span><span class="s2">&quot;Phosphosite&quot;</span><span class="p">]</span> <span class="p">),</span> <span class="n">axis</span> <span class="o">=</span><span class="mi">1</span><span class="p">)</span>

<span class="c1">#dk[14] #Test</span>
<span class="c1">#Use Kinase column (not Gene) from kinase_substrate.csv == Name in Kinase_df.csv.</span>
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<div class=" highlight hl-ipython3"><pre><span></span><span class="n">dd</span><span class="p">[</span><span class="s2">&quot;Kinase&quot;</span><span class="p">]</span><span class="o">=</span> <span class="n">dk</span>
<span class="n">dd</span><span class="o">.</span><span class="n">head</span><span class="p">(</span><span class="mi">50</span><span class="p">)</span>
<span class="c1">#dd.to_csv(&quot;kinasetosplit.csv&quot;)</span>
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<style scoped>
    .dataframe tbody tr th:only-of-type {
        vertical-align: middle;
    }

    .dataframe tbody tr th {
        vertical-align: top;
    }

    .dataframe thead th {
        text-align: right;
    }
</style>
<table border="1" class="dataframe">
  <thead>
    <tr style="text-align: right;">
      <th></th>
      <th>Substrate</th>
      <th>Control_mean</th>
      <th>Inhibitor_mean</th>
      <th>Fold_change</th>
      <th>p_value</th>
      <th>ctrlCV</th>
      <th>treatCV</th>
      <th>Phosphosite</th>
      <th>Sub_gene</th>
      <th>Kinase</th>
    </tr>
  </thead>
  <tbody>
    <tr>
      <th>0</th>
      <td>1A24_HUMAN</td>
      <td>1.527934e+07</td>
      <td>2.643439e+07</td>
      <td>1.730074</td>
      <td>0.554298</td>
      <td>1.280092</td>
      <td>0.902944</td>
      <td>S356</td>
      <td>HLA-A</td>
      <td>None</td>
    </tr>
    <tr>
      <th>1</th>
      <td>1A24_HUMAN</td>
      <td>1.527934e+07</td>
      <td>2.643439e+07</td>
      <td>1.730074</td>
      <td>0.554298</td>
      <td>1.280092</td>
      <td>0.902944</td>
      <td>S359</td>
      <td>HLA-A</td>
      <td>None</td>
    </tr>
    <tr>
      <th>7</th>
      <td>AAAS</td>
      <td>3.886162e+09</td>
      <td>4.023860e+09</td>
      <td>1.035433</td>
      <td>0.798476</td>
      <td>0.118671</td>
      <td>0.190204</td>
      <td>S495</td>
      <td>AAAS</td>
      <td>None</td>
    </tr>
    <tr>
      <th>9</th>
      <td>AAGAB</td>
      <td>1.237204e+07</td>
      <td>5.187831e+06</td>
      <td>0.419319</td>
      <td>0.532084</td>
      <td>1.332381</td>
      <td>1.732051</td>
      <td>S310</td>
      <td>AAGAB</td>
      <td>None</td>
    </tr>
    <tr>
      <th>10</th>
      <td>AAGAB</td>
      <td>1.398521e+07</td>
      <td>5.187831e+06</td>
      <td>0.370951</td>
      <td>0.427256</td>
      <td>1.106864</td>
      <td>1.732051</td>
      <td>S311</td>
      <td>AAGAB</td>
      <td>None</td>
    </tr>
    <tr>
      <th>11</th>
      <td>AAK1</td>
      <td>1.018114e+09</td>
      <td>9.638990e+08</td>
      <td>0.946750</td>
      <td>0.843711</td>
      <td>0.354679</td>
      <td>0.289161</td>
      <td>S14</td>
      <td>AAK1</td>
      <td>None</td>
    </tr>
    <tr>
      <th>12</th>
      <td>AAK1</td>
      <td>2.983340e+07</td>
      <td>1.998685e+08</td>
      <td>6.699488</td>
      <td>0.279794</td>
      <td>1.268167</td>
      <td>1.226010</td>
      <td>S624</td>
      <td>AAK1</td>
      <td>None</td>
    </tr>
    <tr>
      <th>13</th>
      <td>AAK1</td>
      <td>4.201362e+07</td>
      <td>6.203859e+07</td>
      <td>1.476630</td>
      <td>0.000581</td>
      <td>0.107365</td>
      <td>0.043431</td>
      <td>S637</td>
      <td>AAK1</td>
      <td>None</td>
    </tr>
    <tr>
      <th>14</th>
      <td>AAK1</td>
      <td>3.220931e+08</td>
      <td>2.678659e+08</td>
      <td>0.831641</td>
      <td>0.572706</td>
      <td>0.339347</td>
      <td>0.423268</td>
      <td>T389</td>
      <td>AAK1</td>
      <td>CDK1</td>
    </tr>
    <tr>
      <th>15</th>
      <td>AAK1</td>
      <td>1.174191e+09</td>
      <td>1.354491e+09</td>
      <td>1.153553</td>
      <td>0.089500</td>
      <td>0.085950</td>
      <td>0.086223</td>
      <td>T606</td>
      <td>AAK1</td>
      <td>None</td>
    </tr>
    <tr>
      <th>16</th>
      <td>AAK1</td>
      <td>2.983340e+07</td>
      <td>1.998685e+08</td>
      <td>6.699488</td>
      <td>0.279794</td>
      <td>1.268167</td>
      <td>1.226010</td>
      <td>T620</td>
      <td>AAK1</td>
      <td>None</td>
    </tr>
    <tr>
      <th>17</th>
      <td>AAK1</td>
      <td>1.705332e+08</td>
      <td>3.673770e+08</td>
      <td>2.154285</td>
      <td>0.046208</td>
      <td>0.197211</td>
      <td>0.358973</td>
      <td>T653</td>
      <td>AAK1</td>
      <td>None</td>
    </tr>
    <tr>
      <th>19</th>
      <td>AARS2</td>
      <td>2.855109e+09</td>
      <td>2.811485e+09</td>
      <td>0.984721</td>
      <td>0.768347</td>
      <td>0.018414</td>
      <td>0.085172</td>
      <td>S19</td>
      <td>AARS2</td>
      <td>None</td>
    </tr>
    <tr>
      <th>22</th>
      <td>AATF</td>
      <td>2.982143e+09</td>
      <td>3.164170e+09</td>
      <td>1.061039</td>
      <td>0.797772</td>
      <td>0.095957</td>
      <td>0.360818</td>
      <td>S203</td>
      <td>AATF</td>
      <td>None</td>
    </tr>
    <tr>
      <th>23</th>
      <td>AATF</td>
      <td>7.829675e+06</td>
      <td>0.000000e+00</td>
      <td>0.000000</td>
      <td>0.355918</td>
      <td>1.732051</td>
      <td>NaN</td>
      <td>S316</td>
      <td>AATF</td>
      <td>None</td>
    </tr>
    <tr>
      <th>24</th>
      <td>AATF</td>
      <td>3.397402e+08</td>
      <td>3.766364e+08</td>
      <td>1.108601</td>
      <td>0.869873</td>
      <td>0.798732</td>
      <td>0.682567</td>
      <td>S320</td>
      <td>AATF</td>
      <td>None</td>
    </tr>
    <tr>
      <th>25</th>
      <td>AATF</td>
      <td>3.397402e+08</td>
      <td>3.766364e+08</td>
      <td>1.108601</td>
      <td>0.869873</td>
      <td>0.798732</td>
      <td>0.682567</td>
      <td>S321</td>
      <td>AATF</td>
      <td>None</td>
    </tr>
    <tr>
      <th>28</th>
      <td>ABCA2</td>
      <td>6.160821e+07</td>
      <td>1.692898e+08</td>
      <td>2.747845</td>
      <td>0.057258</td>
      <td>0.594418</td>
      <td>0.416502</td>
      <td>S1238</td>
      <td>ABCA2</td>
      <td>None</td>
    </tr>
    <tr>
      <th>29</th>
      <td>ABCA2</td>
      <td>1.131437e+09</td>
      <td>1.095800e+09</td>
      <td>0.968503</td>
      <td>0.845361</td>
      <td>0.157588</td>
      <td>0.223683</td>
      <td>S50</td>
      <td>ABCA2</td>
      <td>None</td>
    </tr>
    <tr>
      <th>31</th>
      <td>ABCA6</td>
      <td>8.738656e+08</td>
      <td>7.933750e+08</td>
      <td>0.907891</td>
      <td>0.831493</td>
      <td>0.499366</td>
      <td>0.567992</td>
      <td>S1238</td>
      <td>ABCA6</td>
      <td>None</td>
    </tr>
    <tr>
      <th>33</th>
      <td>ABCC1</td>
      <td>7.742271e+07</td>
      <td>2.377071e+07</td>
      <td>0.307025</td>
      <td>0.150657</td>
      <td>0.657446</td>
      <td>1.024066</td>
      <td>S916</td>
      <td>ABCC1</td>
      <td>None</td>
    </tr>
    <tr>
      <th>34</th>
      <td>ABCC5</td>
      <td>1.015387e+08</td>
      <td>7.360427e+07</td>
      <td>0.724889</td>
      <td>0.565325</td>
      <td>0.488059</td>
      <td>0.845384</td>
      <td>S509</td>
      <td>ABCC5</td>
      <td>None</td>
    </tr>
    <tr>
      <th>35</th>
      <td>ABCF1</td>
      <td>3.411235e+09</td>
      <td>5.577619e+09</td>
      <td>1.635073</td>
      <td>0.020592</td>
      <td>0.176285</td>
      <td>0.186755</td>
      <td>S105</td>
      <td>ABCF1</td>
      <td>None</td>
    </tr>
    <tr>
      <th>36</th>
      <td>ABCF1</td>
      <td>3.729907e+09</td>
      <td>5.887469e+09</td>
      <td>1.578449</td>
      <td>0.024749</td>
      <td>0.184789</td>
      <td>0.178244</td>
      <td>S109</td>
      <td>ABCF1</td>
      <td>CK2A1</td>
    </tr>
    <tr>
      <th>37</th>
      <td>ABCF1</td>
      <td>5.130510e+09</td>
      <td>3.859859e+09</td>
      <td>0.752334</td>
      <td>0.171288</td>
      <td>0.209021</td>
      <td>0.239829</td>
      <td>S140</td>
      <td>ABCF1</td>
      <td>CK2A1</td>
    </tr>
    <tr>
      <th>38</th>
      <td>ABCF1</td>
      <td>2.839707e+09</td>
      <td>2.980491e+09</td>
      <td>1.049577</td>
      <td>0.744598</td>
      <td>0.238516</td>
      <td>0.076551</td>
      <td>S22</td>
      <td>ABCF1</td>
      <td>None</td>
    </tr>
    <tr>
      <th>39</th>
      <td>ABCF1</td>
      <td>1.332710e+09</td>
      <td>1.672667e+09</td>
      <td>1.255087</td>
      <td>0.161703</td>
      <td>0.226222</td>
      <td>0.127241</td>
      <td>S228</td>
      <td>ABCF1</td>
      <td>None</td>
    </tr>
    <tr>
      <th>40</th>
      <td>ABCF1</td>
      <td>3.729907e+09</td>
      <td>5.887469e+09</td>
      <td>1.578449</td>
      <td>0.024749</td>
      <td>0.184789</td>
      <td>0.178244</td>
      <td>T108</td>
      <td>ABCF1</td>
      <td>None</td>
    </tr>
    <tr>
      <th>42</th>
      <td>ABHD15</td>
      <td>0.000000e+00</td>
      <td>1.154521e+06</td>
      <td>NaN</td>
      <td>0.355918</td>
      <td>NaN</td>
      <td>1.732051</td>
      <td>S434</td>
      <td>ABHD15</td>
      <td>None</td>
    </tr>
    <tr>
      <th>44</th>
      <td>ABI1</td>
      <td>6.954255e+09</td>
      <td>8.002003e+09</td>
      <td>1.150663</td>
      <td>0.274058</td>
      <td>0.131522</td>
      <td>0.149789</td>
      <td>S183</td>
      <td>ABI1</td>
      <td>ERK1,ERK2</td>
    </tr>
    <tr>
      <th>45</th>
      <td>ABI1</td>
      <td>4.674240e+09</td>
      <td>3.291356e+09</td>
      <td>0.704148</td>
      <td>0.367971</td>
      <td>0.452350</td>
      <td>0.382498</td>
      <td>S231</td>
      <td>ABI1</td>
      <td>None</td>
    </tr>
    <tr>
      <th>46</th>
      <td>ABI1</td>
      <td>1.883230e+08</td>
      <td>3.269542e+08</td>
      <td>1.736135</td>
      <td>0.136911</td>
      <td>0.625306</td>
      <td>0.231000</td>
      <td>S319</td>
      <td>ABI1</td>
      <td>None</td>
    </tr>
    <tr>
      <th>47</th>
      <td>ABI1</td>
      <td>1.883230e+08</td>
      <td>3.269542e+08</td>
      <td>1.736135</td>
      <td>0.136911</td>
      <td>0.625306</td>
      <td>0.231000</td>
      <td>S323</td>
      <td>ABI1</td>
      <td>None</td>
    </tr>
    <tr>
      <th>48</th>
      <td>ABI1</td>
      <td>3.553320e+08</td>
      <td>4.794626e+08</td>
      <td>1.349337</td>
      <td>0.121853</td>
      <td>0.043769</td>
      <td>0.246919</td>
      <td>Y213</td>
      <td>ABI1</td>
      <td>Abl</td>
    </tr>
    <tr>
      <th>49</th>
      <td>ABI2</td>
      <td>6.388231e+08</td>
      <td>8.057607e+08</td>
      <td>1.261320</td>
      <td>0.204265</td>
      <td>0.276585</td>
      <td>0.124113</td>
      <td>S216</td>
      <td>ABI2</td>
      <td>None</td>
    </tr>
    <tr>
      <th>50</th>
      <td>ABI2</td>
      <td>4.770793e+09</td>
      <td>5.321400e+09</td>
      <td>1.115412</td>
      <td>0.409644</td>
      <td>0.122516</td>
      <td>0.169814</td>
      <td>S227</td>
      <td>ABI2</td>
      <td>None</td>
    </tr>
    <tr>
      <th>51</th>
      <td>ABI2</td>
      <td>0.000000e+00</td>
      <td>0.000000e+00</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>Y213</td>
      <td>ABI2</td>
      <td>None</td>
    </tr>
    <tr>
      <th>52</th>
      <td>ABL1</td>
      <td>7.414910e+08</td>
      <td>9.130172e+08</td>
      <td>1.231326</td>
      <td>0.101086</td>
      <td>0.070531</td>
      <td>0.158071</td>
      <td>S569</td>
      <td>ABL1</td>
      <td>None</td>
    </tr>
    <tr>
      <th>53</th>
      <td>ABL2</td>
      <td>6.063475e+09</td>
      <td>8.491835e+09</td>
      <td>1.400490</td>
      <td>0.007846</td>
      <td>0.155607</td>
      <td>0.060495</td>
      <td>S620</td>
      <td>ABL2</td>
      <td>None</td>
    </tr>
    <tr>
      <th>54</th>
      <td>ABL2</td>
      <td>1.727886e+09</td>
      <td>1.582168e+09</td>
      <td>0.915667</td>
      <td>0.333418</td>
      <td>0.102937</td>
      <td>0.101820</td>
      <td>S631</td>
      <td>ABL2</td>
      <td>None</td>
    </tr>
    <tr>
      <th>55</th>
      <td>ABL2</td>
      <td>0.000000e+00</td>
      <td>6.558868e+06</td>
      <td>NaN</td>
      <td>0.009935</td>
      <td>NaN</td>
      <td>0.466492</td>
      <td>S655</td>
      <td>ABL2</td>
      <td>None</td>
    </tr>
    <tr>
      <th>56</th>
      <td>ABL2</td>
      <td>3.369007e+07</td>
      <td>1.065180e+08</td>
      <td>3.161702</td>
      <td>0.039066</td>
      <td>1.230324</td>
      <td>0.226592</td>
      <td>S936</td>
      <td>ABL2</td>
      <td>None</td>
    </tr>
    <tr>
      <th>58</th>
      <td>ABLIM1</td>
      <td>0.000000e+00</td>
      <td>0.000000e+00</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>S216</td>
      <td>ABLIM1</td>
      <td>None</td>
    </tr>
    <tr>
      <th>59</th>
      <td>ABLIM1</td>
      <td>1.966385e+07</td>
      <td>5.039010e+06</td>
      <td>0.256258</td>
      <td>0.265097</td>
      <td>0.949597</td>
      <td>1.732051</td>
      <td>S540</td>
      <td>ABLIM1</td>
      <td>None</td>
    </tr>
    <tr>
      <th>60</th>
      <td>ABLIM1</td>
      <td>7.843759e+07</td>
      <td>1.041540e+08</td>
      <td>1.327858</td>
      <td>0.557568</td>
      <td>0.710869</td>
      <td>0.433558</td>
      <td>S640</td>
      <td>ABLIM1</td>
      <td>None</td>
    </tr>
    <tr>
      <th>61</th>
      <td>ABLIM1</td>
      <td>1.165115e+08</td>
      <td>2.101132e+08</td>
      <td>1.803368</td>
      <td>0.009520</td>
      <td>0.330218</td>
      <td>0.093953</td>
      <td>S706</td>
      <td>ABLIM1</td>
      <td>None</td>
    </tr>
    <tr>
      <th>63</th>
      <td>ABR</td>
      <td>3.443238e+07</td>
      <td>2.840068e+07</td>
      <td>0.824825</td>
      <td>0.793890</td>
      <td>0.682262</td>
      <td>1.062680</td>
      <td>S53</td>
      <td>ABR</td>
      <td>None</td>
    </tr>
    <tr>
      <th>64</th>
      <td>ABR</td>
      <td>5.645795e+07</td>
      <td>1.031323e+08</td>
      <td>1.826710</td>
      <td>0.003201</td>
      <td>0.161759</td>
      <td>0.139791</td>
      <td>S632</td>
      <td>ABR</td>
      <td>None</td>
    </tr>
    <tr>
      <th>65</th>
      <td>ABR</td>
      <td>1.419410e+06</td>
      <td>4.745870e+06</td>
      <td>3.343552</td>
      <td>0.526880</td>
      <td>1.732051</td>
      <td>1.732051</td>
      <td>S72</td>
      <td>ABR</td>
      <td>None</td>
    </tr>
    <tr>
      <th>66</th>
      <td>ABR</td>
      <td>4.071807e+08</td>
      <td>3.734379e+08</td>
      <td>0.917131</td>
      <td>0.674603</td>
      <td>0.280342</td>
      <td>0.180162</td>
      <td>T74</td>
      <td>ABR</td>
      <td>None</td>
    </tr>
  </tbody>
</table>
</div>
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<div class=" highlight hl-ipython3"><pre><span></span><span class="c1"># split multiple kinases to one substrate/phosphosite into individual rows</span>
<span class="n">dd</span> <span class="o">=</span> <span class="n">dd</span><span class="o">.</span><span class="n">join</span><span class="p">(</span><span class="n">dd</span><span class="o">.</span><span class="n">pop</span><span class="p">(</span><span class="s1">&#39;Kinase&#39;</span><span class="p">)</span>
                   <span class="o">.</span><span class="n">str</span><span class="o">.</span><span class="n">strip</span><span class="p">(</span><span class="s1">&#39;,&#39;</span><span class="p">)</span>
                   <span class="o">.</span><span class="n">str</span><span class="o">.</span><span class="n">split</span><span class="p">(</span><span class="s1">&#39;,&#39;</span><span class="p">,</span> <span class="n">expand</span><span class="o">=</span><span class="kc">True</span><span class="p">)</span>
                   <span class="o">.</span><span class="n">stack</span><span class="p">()</span>
                   <span class="o">.</span><span class="n">reset_index</span><span class="p">(</span><span class="n">level</span><span class="o">=</span><span class="mi">1</span><span class="p">,</span> <span class="n">drop</span><span class="o">=</span><span class="kc">True</span><span class="p">)</span>
                   <span class="o">.</span><span class="n">rename</span><span class="p">(</span><span class="s1">&#39;Kinase&#39;</span><span class="p">))</span><span class="o">.</span><span class="n">reset_index</span><span class="p">(</span><span class="n">drop</span><span class="o">=</span><span class="kc">True</span><span class="p">)</span>
</pre></div>

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<div class="prompt input_prompt">In&nbsp;[39]:</div>
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<div class=" highlight hl-ipython3"><pre><span></span><span class="k">def</span> <span class="nf">cv_filter</span><span class="p">(</span><span class="n">dd</span><span class="p">,</span> <span class="n">CV_P</span><span class="p">):</span>

    <span class="n">dd</span><span class="o">=</span> <span class="n">dd</span><span class="o">.</span><span class="n">loc</span><span class="p">[(</span><span class="n">dd</span><span class="p">[</span><span class="s1">&#39;ctrlCV&#39;</span><span class="p">]</span> <span class="o">&lt;=</span>  <span class="n">CV_P</span><span class="p">)</span> <span class="o">&amp;</span> <span class="p">(</span><span class="n">dd</span><span class="p">[</span><span class="s1">&#39;treatCV&#39;</span><span class="p">]</span> <span class="o">&lt;=</span> <span class="n">CV_P</span><span class="p">)]</span>   <span class="c1">#user define CV value: Rows Above CV_P filtered out </span>
    <span class="k">return</span> <span class="n">dd</span>

<span class="n">cv_filter</span><span class="p">(</span><span class="n">dd</span><span class="p">,</span> <span class="mf">1.0</span><span class="p">)</span>
<span class="c1">#dd.to_csv(&quot;check.csv&quot;)</span>
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<div class="prompt output_prompt">Out[39]:</div>


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<style scoped>
    .dataframe tbody tr th:only-of-type {
        vertical-align: middle;
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    }

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        text-align: right;
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</style>
<table border="1" class="dataframe">
  <thead>
    <tr style="text-align: right;">
      <th></th>
      <th>Substrate</th>
      <th>Control_mean</th>
      <th>Inhibitor_mean</th>
      <th>Fold_change</th>
      <th>p_value</th>
      <th>ctrlCV</th>
      <th>treatCV</th>
      <th>Phosphosite</th>
      <th>Sub_gene</th>
      <th>Kinase</th>
      <th>color</th>
      <th>log_pvalue</th>
      <th>log_FC</th>
    </tr>
  </thead>
  <tbody>
    <tr>
      <th>8</th>
      <td>AAK1</td>
      <td>3.220931e+08</td>
      <td>2.678659e+08</td>
      <td>0.831641</td>
      <td>0.572706</td>
      <td>0.339347</td>
      <td>0.423268</td>
      <td>T389</td>
      <td>AAK1</td>
      <td>CDK1</td>
      <td>grey</td>
      <td>0.242068</td>
      <td>-0.265967</td>
    </tr>
    <tr>
      <th>23</th>
      <td>ABCF1</td>
      <td>3.729907e+09</td>
      <td>5.887469e+09</td>
      <td>1.578449</td>
      <td>0.024749</td>
      <td>0.184789</td>
      <td>0.178244</td>
      <td>S109</td>
      <td>ABCF1</td>
      <td>CK2A1</td>
      <td>Blue</td>
      <td>1.606443</td>
      <td>0.658508</td>
    </tr>
    <tr>
      <th>24</th>
      <td>ABCF1</td>
      <td>5.130510e+09</td>
      <td>3.859859e+09</td>
      <td>0.752334</td>
      <td>0.171288</td>
      <td>0.209021</td>
      <td>0.239829</td>
      <td>S140</td>
      <td>ABCF1</td>
      <td>CK2A1</td>
      <td>grey</td>
      <td>0.766272</td>
      <td>-0.410554</td>
    </tr>
    <tr>
      <th>29</th>
      <td>ABI1</td>
      <td>6.954255e+09</td>
      <td>8.002003e+09</td>
      <td>1.150663</td>
      <td>0.274058</td>
      <td>0.131522</td>
      <td>0.149789</td>
      <td>S183</td>
      <td>ABI1</td>
      <td>ERK1</td>
      <td>grey</td>
      <td>0.562157</td>
      <td>0.202465</td>
    </tr>
    <tr>
      <th>30</th>
      <td>ABI1</td>
      <td>6.954255e+09</td>
      <td>8.002003e+09</td>
      <td>1.150663</td>
      <td>0.274058</td>
      <td>0.131522</td>
      <td>0.149789</td>
      <td>S183</td>
      <td>ABI1</td>
      <td>ERK2</td>
      <td>grey</td>
      <td>0.562157</td>
      <td>0.202465</td>
    </tr>
    <tr>
      <th>34</th>
      <td>ABI1</td>
      <td>3.553320e+08</td>
      <td>4.794626e+08</td>
      <td>1.349337</td>
      <td>0.121853</td>
      <td>0.043769</td>
      <td>0.246919</td>
      <td>Y213</td>
      <td>ABI1</td>
      <td>Abl</td>
      <td>grey</td>
      <td>0.914164</td>
      <td>0.432251</td>
    </tr>
    <tr>
      <th>54</th>
      <td>ACACA</td>
      <td>9.367416e+08</td>
      <td>1.819075e+09</td>
      <td>1.941918</td>
      <td>0.006910</td>
      <td>0.140979</td>
      <td>0.195626</td>
      <td>S80</td>
      <td>ACACA</td>
      <td>AMPKA1</td>
      <td>Blue</td>
      <td>2.160533</td>
      <td>0.957482</td>
    </tr>
    <tr>
      <th>55</th>
      <td>ACACA</td>
      <td>9.367416e+08</td>
      <td>1.819075e+09</td>
      <td>1.941918</td>
      <td>0.006910</td>
      <td>0.140979</td>
      <td>0.195626</td>
      <td>S80</td>
      <td>ACACA</td>
      <td>AMPKA2</td>
      <td>Blue</td>
      <td>2.160533</td>
      <td>0.957482</td>
    </tr>
    <tr>
      <th>127</th>
      <td>ADD2</td>
      <td>1.747978e+09</td>
      <td>3.721304e+08</td>
      <td>0.212892</td>
      <td>0.007357</td>
      <td>0.312763</td>
      <td>0.664823</td>
      <td>S613</td>
      <td>ADD2</td>
      <td>GSK3B</td>
      <td>Purple</td>
      <td>2.133321</td>
      <td>-2.231807</td>
    </tr>
    <tr>
      <th>132</th>
      <td>ADD3</td>
      <td>4.823210e+09</td>
      <td>5.171387e+09</td>
      <td>1.072188</td>
      <td>0.487553</td>
      <td>0.073165</td>
      <td>0.142181</td>
      <td>S693</td>
      <td>ADD3</td>
      <td>Chk1</td>
      <td>grey</td>
      <td>0.311978</td>
      <td>0.100558</td>
    </tr>
    <tr>
      <th>194</th>
      <td>AGO2</td>
      <td>7.351497e+08</td>
      <td>5.564733e+08</td>
      <td>0.756952</td>
      <td>0.100504</td>
      <td>0.172695</td>
      <td>0.173687</td>
      <td>S387</td>
      <td>AGO2</td>
      <td>MAPKAPK2</td>
      <td>grey</td>
      <td>0.997816</td>
      <td>-0.401726</td>
    </tr>
    <tr>
      <th>195</th>
      <td>AGO2</td>
      <td>7.351497e+08</td>
      <td>5.564733e+08</td>
      <td>0.756952</td>
      <td>0.100504</td>
      <td>0.172695</td>
      <td>0.173687</td>
      <td>S387</td>
      <td>AGO2</td>
      <td>Akt3</td>
      <td>grey</td>
      <td>0.997816</td>
      <td>-0.401726</td>
    </tr>
    <tr>
      <th>259</th>
      <td>AJUBA</td>
      <td>1.585271e+09</td>
      <td>1.362069e+09</td>
      <td>0.859203</td>
      <td>0.227568</td>
      <td>0.062152</td>
      <td>0.198425</td>
      <td>S119</td>
      <td>AJUBA</td>
      <td>CDK1</td>
      <td>grey</td>
      <td>0.642888</td>
      <td>-0.218930</td>
    </tr>
    <tr>
      <th>291</th>
      <td>AKAP12</td>
      <td>1.408803e+08</td>
      <td>7.187235e+08</td>
      <td>5.101659</td>
      <td>0.127881</td>
      <td>0.651484</td>
      <td>0.778252</td>
      <td>S627</td>
      <td>AKAP12</td>
      <td>PKACA</td>
      <td>grey</td>
      <td>0.893195</td>
      <td>2.350967</td>
    </tr>
    <tr>
      <th>297</th>
      <td>AKAP12</td>
      <td>7.799472e+08</td>
      <td>8.798277e+08</td>
      <td>1.128061</td>
      <td>0.218834</td>
      <td>0.122885</td>
      <td>0.092953</td>
      <td>T767</td>
      <td>AKAP12</td>
      <td>CDK1</td>
      <td>grey</td>
      <td>0.659884</td>
      <td>0.173845</td>
    </tr>
    <tr>
      <th>300</th>
      <td>AKAP13</td>
      <td>6.066856e+08</td>
      <td>5.866112e+08</td>
      <td>0.966911</td>
      <td>0.878155</td>
      <td>0.095552</td>
      <td>0.357103</td>
      <td>S1565</td>
      <td>AKAP13</td>
      <td>PKACA</td>
      <td>grey</td>
      <td>0.056429</td>
      <td>-0.048544</td>
    </tr>
    <tr>
      <th>327</th>
      <td>AKIRIN2</td>
      <td>1.909108e+08</td>
      <td>3.181032e+08</td>
      <td>1.666240</td>
      <td>0.023345</td>
      <td>0.322419</td>
      <td>0.122824</td>
      <td>S18</td>
      <td>AKIRIN2</td>
      <td>CDK2</td>
      <td>Blue</td>
      <td>1.631812</td>
      <td>0.736597</td>
    </tr>
    <tr>
      <th>328</th>
      <td>AKIRIN2</td>
      <td>4.528564e+08</td>
      <td>5.791934e+08</td>
      <td>1.278978</td>
      <td>0.063204</td>
      <td>0.090704</td>
      <td>0.150137</td>
      <td>S21</td>
      <td>AKIRIN2</td>
      <td>CDK2</td>
      <td>grey</td>
      <td>1.199257</td>
      <td>0.354991</td>
    </tr>
    <tr>
      <th>333</th>
      <td>AKT1</td>
      <td>3.132603e+09</td>
      <td>5.156830e+09</td>
      <td>1.646181</td>
      <td>0.179509</td>
      <td>0.317100</td>
      <td>0.403941</td>
      <td>S129</td>
      <td>AKT1</td>
      <td>CK2A1</td>
      <td>grey</td>
      <td>0.745914</td>
      <td>0.719123</td>
    </tr>
    <tr>
      <th>334</th>
      <td>AKT1</td>
      <td>5.158378e+08</td>
      <td>2.204069e+08</td>
      <td>0.427279</td>
      <td>0.222719</td>
      <td>0.602235</td>
      <td>0.963148</td>
      <td>S473</td>
      <td>AKT1</td>
      <td>TBK1</td>
      <td>grey</td>
      <td>0.652242</td>
      <td>-1.226748</td>
    </tr>
    <tr>
      <th>335</th>
      <td>AKT1</td>
      <td>5.158378e+08</td>
      <td>2.204069e+08</td>
      <td>0.427279</td>
      <td>0.222719</td>
      <td>0.602235</td>
      <td>0.963148</td>
      <td>S473</td>
      <td>AKT1</td>
      <td>MAPKAPK2</td>
      <td>grey</td>
      <td>0.652242</td>
      <td>-1.226748</td>
    </tr>
    <tr>
      <th>336</th>
      <td>AKT1</td>
      <td>5.158378e+08</td>
      <td>2.204069e+08</td>
      <td>0.427279</td>
      <td>0.222719</td>
      <td>0.602235</td>
      <td>0.963148</td>
      <td>S473</td>
      <td>AKT1</td>
      <td>ILK</td>
      <td>grey</td>
      <td>0.652242</td>
      <td>-1.226748</td>
    </tr>
    <tr>
      <th>337</th>
      <td>AKT1</td>
      <td>5.158378e+08</td>
      <td>2.204069e+08</td>
      <td>0.427279</td>
      <td>0.222719</td>
      <td>0.602235</td>
      <td>0.963148</td>
      <td>S473</td>
      <td>AKT1</td>
      <td>DNAPK</td>
      <td>grey</td>
      <td>0.652242</td>
      <td>-1.226748</td>
    </tr>
    <tr>
      <th>338</th>
      <td>AKT1</td>
      <td>5.158378e+08</td>
      <td>2.204069e+08</td>
      <td>0.427279</td>
      <td>0.222719</td>
      <td>0.602235</td>
      <td>0.963148</td>
      <td>S473</td>
      <td>AKT1</td>
      <td>PIKFYVE</td>
      <td>grey</td>
      <td>0.652242</td>
      <td>-1.226748</td>
    </tr>
    <tr>
      <th>339</th>
      <td>AKT1</td>
      <td>5.158378e+08</td>
      <td>2.204069e+08</td>
      <td>0.427279</td>
      <td>0.222719</td>
      <td>0.602235</td>
      <td>0.963148</td>
      <td>S473</td>
      <td>AKT1</td>
      <td>PRKD1</td>
      <td>grey</td>
      <td>0.652242</td>
      <td>-1.226748</td>
    </tr>
    <tr>
      <th>340</th>
      <td>AKT1</td>
      <td>5.158378e+08</td>
      <td>2.204069e+08</td>
      <td>0.427279</td>
      <td>0.222719</td>
      <td>0.602235</td>
      <td>0.963148</td>
      <td>S473</td>
      <td>AKT1</td>
      <td>IKKE</td>
      <td>grey</td>
      <td>0.652242</td>
      <td>-1.226748</td>
    </tr>
    <tr>
      <th>341</th>
      <td>AKT1</td>
      <td>5.158378e+08</td>
      <td>2.204069e+08</td>
      <td>0.427279</td>
      <td>0.222719</td>
      <td>0.602235</td>
      <td>0.963148</td>
      <td>S473</td>
      <td>AKT1</td>
      <td>PDK1</td>
      <td>grey</td>
      <td>0.652242</td>
      <td>-1.226748</td>
    </tr>
    <tr>
      <th>342</th>
      <td>AKT1</td>
      <td>5.158378e+08</td>
      <td>2.204069e+08</td>
      <td>0.427279</td>
      <td>0.222719</td>
      <td>0.602235</td>
      <td>0.963148</td>
      <td>S473</td>
      <td>AKT1</td>
      <td>LRRK2</td>
      <td>grey</td>
      <td>0.652242</td>
      <td>-1.226748</td>
    </tr>
    <tr>
      <th>343</th>
      <td>AKT1</td>
      <td>5.158378e+08</td>
      <td>2.204069e+08</td>
      <td>0.427279</td>
      <td>0.222719</td>
      <td>0.602235</td>
      <td>0.963148</td>
      <td>S473</td>
      <td>AKT1</td>
      <td>mTOR</td>
      <td>grey</td>
      <td>0.652242</td>
      <td>-1.226748</td>
    </tr>
    <tr>
      <th>344</th>
      <td>AKT1</td>
      <td>5.158378e+08</td>
      <td>2.204069e+08</td>
      <td>0.427279</td>
      <td>0.222719</td>
      <td>0.602235</td>
      <td>0.963148</td>
      <td>S473</td>
      <td>AKT1</td>
      <td>Mer</td>
      <td>grey</td>
      <td>0.652242</td>
      <td>-1.226748</td>
    </tr>
    <tr>
      <th>345</th>
      <td>AKT1</td>
      <td>5.158378e+08</td>
      <td>2.204069e+08</td>
      <td>0.427279</td>
      <td>0.222719</td>
      <td>0.602235</td>
      <td>0.963148</td>
      <td>S473</td>
      <td>AKT1</td>
      <td>PKCA</td>
      <td>grey</td>
      <td>0.652242</td>
      <td>-1.226748</td>
    </tr>
    <tr>
      <th>346</th>
      <td>AKT1</td>
      <td>5.158378e+08</td>
      <td>2.204069e+08</td>
      <td>0.427279</td>
      <td>0.222719</td>
      <td>0.602235</td>
      <td>0.963148</td>
      <td>S473</td>
      <td>AKT1</td>
      <td>PKCB</td>
      <td>grey</td>
      <td>0.652242</td>
      <td>-1.226748</td>
    </tr>
    <tr>
      <th>347</th>
      <td>AKT1</td>
      <td>5.158378e+08</td>
      <td>2.204069e+08</td>
      <td>0.427279</td>
      <td>0.222719</td>
      <td>0.602235</td>
      <td>0.963148</td>
      <td>S473</td>
      <td>AKT1</td>
      <td>AXL</td>
      <td>grey</td>
      <td>0.652242</td>
      <td>-1.226748</td>
    </tr>
    <tr>
      <th>351</th>
      <td>AKT1S1</td>
      <td>6.105962e+08</td>
      <td>2.176100e+08</td>
      <td>0.356389</td>
      <td>0.008361</td>
      <td>0.284972</td>
      <td>0.131286</td>
      <td>S183</td>
      <td>AKT1S1</td>
      <td>mTOR</td>
      <td>Purple</td>
      <td>2.077753</td>
      <td>-1.488474</td>
    </tr>
    <tr>
      <th>352</th>
      <td>AKT1S1</td>
      <td>6.457577e+07</td>
      <td>4.417949e+07</td>
      <td>0.684150</td>
      <td>0.603906</td>
      <td>0.941097</td>
      <td>0.492271</td>
      <td>S203</td>
      <td>AKT1S1</td>
      <td>PKM</td>
      <td>grey</td>
      <td>0.219031</td>
      <td>-0.547616</td>
    </tr>
    <tr>
      <th>389</th>
      <td>AMOTL2</td>
      <td>3.350480e+08</td>
      <td>4.094197e+08</td>
      <td>1.221973</td>
      <td>0.337128</td>
      <td>0.195167</td>
      <td>0.255900</td>
      <td>S759</td>
      <td>AMOTL2</td>
      <td>mTOR</td>
      <td>grey</td>
      <td>0.472205</td>
      <td>0.289213</td>
    </tr>
    <tr>
      <th>401</th>
      <td>ANAPC1</td>
      <td>2.308922e+08</td>
      <td>3.231128e+08</td>
      <td>1.399410</td>
      <td>0.011624</td>
      <td>0.133089</td>
      <td>0.100042</td>
      <td>S355</td>
      <td>ANAPC1</td>
      <td>CDK1</td>
      <td>Blue</td>
      <td>1.934655</td>
      <td>0.484818</td>
    </tr>
    <tr>
      <th>402</th>
      <td>ANAPC1</td>
      <td>2.308922e+08</td>
      <td>3.231128e+08</td>
      <td>1.399410</td>
      <td>0.011624</td>
      <td>0.133089</td>
      <td>0.100042</td>
      <td>S355</td>
      <td>ANAPC1</td>
      <td>PLK1</td>
      <td>Blue</td>
      <td>1.934655</td>
      <td>0.484818</td>
    </tr>
    <tr>
      <th>403</th>
      <td>ANAPC1</td>
      <td>2.688357e+08</td>
      <td>5.950942e+08</td>
      <td>2.213598</td>
      <td>0.033918</td>
      <td>0.546590</td>
      <td>0.243914</td>
      <td>S377</td>
      <td>ANAPC1</td>
      <td>CDK1</td>
      <td>Blue</td>
      <td>1.469570</td>
      <td>1.146393</td>
    </tr>
    <tr>
      <th>404</th>
      <td>ANAPC1</td>
      <td>2.688357e+08</td>
      <td>5.950942e+08</td>
      <td>2.213598</td>
      <td>0.033918</td>
      <td>0.546590</td>
      <td>0.243914</td>
      <td>S377</td>
      <td>ANAPC1</td>
      <td>PLK1</td>
      <td>Blue</td>
      <td>1.469570</td>
      <td>1.146393</td>
    </tr>
  </tbody>
</table>
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<div class="prompt input_prompt">In&nbsp;[40]:</div>
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<div class=" highlight hl-ipython3"><pre><span></span><span class="k">def</span> <span class="nf">pv_filter</span><span class="p">(</span><span class="n">dd</span><span class="p">,</span> <span class="n">PV_P</span><span class="p">):</span>

    <span class="n">dd</span><span class="o">=</span> <span class="n">dd</span><span class="o">.</span><span class="n">loc</span><span class="p">[(</span><span class="n">dd</span><span class="p">[</span><span class="s1">&#39;p_value&#39;</span><span class="p">]</span> <span class="o">&lt;=</span>  <span class="n">PV_P</span><span class="p">)]</span>   <span class="c1">#user define CV value: Rows Above CV_P filtered out </span>
    <span class="k">return</span> <span class="n">dd</span>

<span class="n">pv_filter</span><span class="p">(</span><span class="n">dd</span><span class="p">,</span> <span class="mf">0.05</span><span class="p">)</span>
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<div class="prompt output_prompt">Out[40]:</div>


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<style scoped>
    .dataframe tbody tr th:only-of-type {
        vertical-align: middle;
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    .dataframe tbody tr th {
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        text-align: right;
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<table border="1" class="dataframe">
  <thead>
    <tr style="text-align: right;">
      <th></th>
      <th>Substrate</th>
      <th>Control_mean</th>
      <th>Inhibitor_mean</th>
      <th>Fold_change</th>
      <th>p_value</th>
      <th>ctrlCV</th>
      <th>treatCV</th>
      <th>Phosphosite</th>
      <th>Sub_gene</th>
      <th>Kinase</th>
      <th>color</th>
      <th>log_pvalue</th>
      <th>log_FC</th>
    </tr>
  </thead>
  <tbody>
    <tr>
      <th>23</th>
      <td>ABCF1</td>
      <td>3.729907e+09</td>
      <td>5.887469e+09</td>
      <td>1.578449</td>
      <td>0.024749</td>
      <td>0.184789</td>
      <td>0.178244</td>
      <td>S109</td>
      <td>ABCF1</td>
      <td>CK2A1</td>
      <td>Blue</td>
      <td>1.606443</td>
      <td>0.658508</td>
    </tr>
    <tr>
      <th>54</th>
      <td>ACACA</td>
      <td>9.367416e+08</td>
      <td>1.819075e+09</td>
      <td>1.941918</td>
      <td>0.006910</td>
      <td>0.140979</td>
      <td>0.195626</td>
      <td>S80</td>
      <td>ACACA</td>
      <td>AMPKA1</td>
      <td>Blue</td>
      <td>2.160533</td>
      <td>0.957482</td>
    </tr>
    <tr>
      <th>55</th>
      <td>ACACA</td>
      <td>9.367416e+08</td>
      <td>1.819075e+09</td>
      <td>1.941918</td>
      <td>0.006910</td>
      <td>0.140979</td>
      <td>0.195626</td>
      <td>S80</td>
      <td>ACACA</td>
      <td>AMPKA2</td>
      <td>Blue</td>
      <td>2.160533</td>
      <td>0.957482</td>
    </tr>
    <tr>
      <th>127</th>
      <td>ADD2</td>
      <td>1.747978e+09</td>
      <td>3.721304e+08</td>
      <td>0.212892</td>
      <td>0.007357</td>
      <td>0.312763</td>
      <td>0.664823</td>
      <td>S613</td>
      <td>ADD2</td>
      <td>GSK3B</td>
      <td>Purple</td>
      <td>2.133321</td>
      <td>-2.231807</td>
    </tr>
    <tr>
      <th>327</th>
      <td>AKIRIN2</td>
      <td>1.909108e+08</td>
      <td>3.181032e+08</td>
      <td>1.666240</td>
      <td>0.023345</td>
      <td>0.322419</td>
      <td>0.122824</td>
      <td>S18</td>
      <td>AKIRIN2</td>
      <td>CDK2</td>
      <td>Blue</td>
      <td>1.631812</td>
      <td>0.736597</td>
    </tr>
    <tr>
      <th>351</th>
      <td>AKT1S1</td>
      <td>6.105962e+08</td>
      <td>2.176100e+08</td>
      <td>0.356389</td>
      <td>0.008361</td>
      <td>0.284972</td>
      <td>0.131286</td>
      <td>S183</td>
      <td>AKT1S1</td>
      <td>mTOR</td>
      <td>Purple</td>
      <td>2.077753</td>
      <td>-1.488474</td>
    </tr>
    <tr>
      <th>401</th>
      <td>ANAPC1</td>
      <td>2.308922e+08</td>
      <td>3.231128e+08</td>
      <td>1.399410</td>
      <td>0.011624</td>
      <td>0.133089</td>
      <td>0.100042</td>
      <td>S355</td>
      <td>ANAPC1</td>
      <td>CDK1</td>
      <td>Blue</td>
      <td>1.934655</td>
      <td>0.484818</td>
    </tr>
    <tr>
      <th>402</th>
      <td>ANAPC1</td>
      <td>2.308922e+08</td>
      <td>3.231128e+08</td>
      <td>1.399410</td>
      <td>0.011624</td>
      <td>0.133089</td>
      <td>0.100042</td>
      <td>S355</td>
      <td>ANAPC1</td>
      <td>PLK1</td>
      <td>Blue</td>
      <td>1.934655</td>
      <td>0.484818</td>
    </tr>
    <tr>
      <th>403</th>
      <td>ANAPC1</td>
      <td>2.688357e+08</td>
      <td>5.950942e+08</td>
      <td>2.213598</td>
      <td>0.033918</td>
      <td>0.546590</td>
      <td>0.243914</td>
      <td>S377</td>
      <td>ANAPC1</td>
      <td>CDK1</td>
      <td>Blue</td>
      <td>1.469570</td>
      <td>1.146393</td>
    </tr>
    <tr>
      <th>404</th>
      <td>ANAPC1</td>
      <td>2.688357e+08</td>
      <td>5.950942e+08</td>
      <td>2.213598</td>
      <td>0.033918</td>
      <td>0.546590</td>
      <td>0.243914</td>
      <td>S377</td>
      <td>ANAPC1</td>
      <td>PLK1</td>
      <td>Blue</td>
      <td>1.469570</td>
      <td>1.146393</td>
    </tr>
  </tbody>
</table>
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<div class="cell border-box-sizing code_cell rendered">
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<div class="prompt input_prompt">In&nbsp;[16]:</div>
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<div class=" highlight hl-ipython3"><pre><span></span><span class="k">def</span> <span class="nf">makeplot</span><span class="p">(</span><span class="n">df</span><span class="p">,</span> <span class="n">FC_P</span><span class="p">,</span> <span class="n">PV_P</span><span class="p">,</span> <span class="n">Inhibitor</span><span class="p">):</span>
    

    <span class="n">df</span><span class="o">.</span><span class="n">loc</span><span class="p">[(</span><span class="n">df</span><span class="p">[</span><span class="s1">&#39;Fold_change&#39;</span><span class="p">]</span> <span class="o">&gt;</span> <span class="n">FC_P</span><span class="p">)</span> <span class="o">&amp;</span> <span class="p">(</span><span class="n">df</span><span class="p">[</span><span class="s1">&#39;p_value&#39;</span><span class="p">]</span> <span class="o">&lt;</span> <span class="n">PV_P</span><span class="p">),</span> <span class="s1">&#39;color&#39;</span><span class="p">]</span> <span class="o">=</span> <span class="s2">&quot;green&quot;</span>  <span class="c1"># upregulated</span>
    <span class="c1">#df.loc - Selects single row or subset of rows from the DataFrame by label</span>
    <span class="n">df</span><span class="o">.</span><span class="n">loc</span><span class="p">[(</span><span class="n">df</span><span class="p">[</span><span class="s1">&#39;Fold_change&#39;</span><span class="p">]</span> <span class="o">&lt;=</span><span class="n">FC_P</span><span class="p">)</span> <span class="o">&amp;</span> <span class="p">(</span><span class="n">df</span><span class="p">[</span><span class="s1">&#39;p_value&#39;</span><span class="p">]</span> <span class="o">&lt;</span> <span class="n">PV_P</span><span class="p">),</span> <span class="s1">&#39;color&#39;</span><span class="p">]</span> <span class="o">=</span> <span class="s2">&quot;red&quot;</span>   <span class="c1"># downregulated</span>
    <span class="n">df</span><span class="p">[</span><span class="s1">&#39;color&#39;</span><span class="p">]</span><span class="o">.</span><span class="n">fillna</span><span class="p">(</span><span class="s1">&#39;grey&#39;</span><span class="p">,</span> <span class="n">inplace</span><span class="o">=</span><span class="kc">True</span><span class="p">)</span>


    <span class="n">df</span><span class="p">[</span><span class="s2">&quot;log_pvalue&quot;</span><span class="p">]</span> <span class="o">=</span> <span class="o">-</span><span class="n">np</span><span class="o">.</span><span class="n">log10</span><span class="p">(</span><span class="n">df</span><span class="p">[</span><span class="s1">&#39;p_value&#39;</span><span class="p">])</span>
    <span class="n">df</span><span class="p">[</span><span class="s2">&quot;log_FC&quot;</span><span class="p">]</span><span class="o">=</span><span class="n">np</span><span class="o">.</span><span class="n">log2</span><span class="p">(</span><span class="n">df</span><span class="p">[</span><span class="s1">&#39;Fold_change&#39;</span><span class="p">])</span>

    <span class="n">df</span><span class="o">.</span><span class="n">head</span><span class="p">()</span>


    <span class="kn">from</span> <span class="nn">bokeh.plotting</span> <span class="k">import</span> <span class="n">figure</span><span class="p">,</span> <span class="n">ColumnDataSource</span><span class="p">,</span> <span class="n">output_notebook</span><span class="p">,</span> <span class="n">show</span>
    <span class="kn">from</span> <span class="nn">bokeh.models</span> <span class="k">import</span> <span class="n">HoverTool</span><span class="p">,</span> <span class="n">WheelZoomTool</span><span class="p">,</span> <span class="n">PanTool</span><span class="p">,</span> <span class="n">BoxZoomTool</span><span class="p">,</span> <span class="n">ResetTool</span><span class="p">,</span> <span class="n">TapTool</span><span class="p">,</span> <span class="n">SaveTool</span>
    <span class="kn">from</span> <span class="nn">bokeh.palettes</span> <span class="k">import</span> <span class="n">brewer</span>


    <span class="n">output_notebook</span><span class="p">()</span>


    <span class="n">category</span> <span class="o">=</span> <span class="s1">&#39;Substrate&#39;</span>

    <span class="n">category_items</span> <span class="o">=</span> <span class="n">df</span><span class="p">[</span><span class="n">category</span><span class="p">]</span><span class="o">.</span><span class="n">unique</span><span class="p">()</span>

    <span class="n">title</span> <span class="o">=</span> <span class="n">Inhibitor</span> <span class="o">+</span> <span class="s2">&quot; : Data Summary&quot;</span>
    <span class="c1">#feeding data into ColumnDataSource</span>
    <span class="n">source</span> <span class="o">=</span> <span class="n">ColumnDataSource</span><span class="p">(</span><span class="n">df</span><span class="p">)</span>
    <span class="c1">#Editing the hover that need to displayed while hovering</span>
    <span class="n">hover</span> <span class="o">=</span> <span class="n">HoverTool</span><span class="p">(</span><span class="n">tooltips</span><span class="o">=</span><span class="p">[(</span><span class="s1">&#39;Kinase&#39;</span><span class="p">,</span><span class="s1">&#39;@Kinase&#39;</span><span class="p">),</span>
                                <span class="p">(</span><span class="s1">&#39;Substrate&#39;</span><span class="p">,</span> <span class="s1">&#39;@Substrate&#39;</span><span class="p">),</span>
                                <span class="p">(</span><span class="s1">&#39;Sub_gene&#39;</span><span class="p">,</span><span class="s1">&#39;@Sub_gene&#39;</span><span class="p">),</span>
                                <span class="p">(</span><span class="s1">&#39;Phosphosite&#39;</span><span class="p">,</span> <span class="s1">&#39;@Phosphosite&#39;</span><span class="p">),</span>
                               <span class="p">(</span><span class="s1">&#39;Fold_change&#39;</span><span class="p">,</span> <span class="s1">&#39;@Fold_change&#39;</span><span class="p">),</span>
                               <span class="p">(</span><span class="s1">&#39;p_value&#39;</span><span class="p">,</span> <span class="s1">&#39;@p_value&#39;</span><span class="p">)])</span>
    <span class="c1">#tools that are need to explote data</span>
    <span class="n">tools</span> <span class="o">=</span> <span class="p">[</span><span class="n">hover</span><span class="p">,</span> <span class="n">WheelZoomTool</span><span class="p">(),</span> <span class="n">PanTool</span><span class="p">(),</span> <span class="n">BoxZoomTool</span><span class="p">(),</span> <span class="n">ResetTool</span><span class="p">(),</span> <span class="n">SaveTool</span><span class="p">()]</span>
    

    <span class="c1">#finally making figure with scatter plot</span>
    <span class="n">p</span> <span class="o">=</span> <span class="n">figure</span><span class="p">(</span><span class="n">tools</span><span class="o">=</span><span class="n">tools</span><span class="p">,</span><span class="n">title</span><span class="o">=</span><span class="n">title</span><span class="p">,</span><span class="n">plot_width</span><span class="o">=</span><span class="mi">700</span><span class="p">,</span><span class="n">plot_height</span><span class="o">=</span><span class="mi">400</span><span class="p">,</span><span class="n">toolbar_location</span><span class="o">=</span><span class="s1">&#39;right&#39;</span><span class="p">,</span><span class="n">toolbar_sticky</span><span class="o">=</span><span class="kc">False</span><span class="p">,</span> <span class="p">)</span>
   
    <span class="n">p</span><span class="o">.</span><span class="n">scatter</span><span class="p">(</span><span class="n">x</span><span class="o">=</span><span class="s1">&#39;log_FC&#39;</span><span class="p">,</span><span class="n">y</span><span class="o">=</span><span class="s1">&#39;log_pvalue&#39;</span><span class="p">,</span><span class="n">source</span><span class="o">=</span><span class="n">source</span><span class="p">,</span><span class="n">size</span><span class="o">=</span><span class="mi">10</span><span class="p">,</span><span class="n">color</span><span class="o">=</span><span class="s1">&#39;color&#39;</span><span class="p">)</span>
    
    <span class="c1">#displaying the graph</span>
    <span class="n">show</span><span class="p">(</span><span class="n">p</span><span class="p">)</span>
    
<span class="n">makeplot</span><span class="p">(</span><span class="n">dd</span><span class="p">,</span> <span class="mf">1.0</span><span class="p">,</span> <span class="mf">0.05</span><span class="p">,</span> <span class="s2">&quot;AZ20&quot;</span><span class="p">)</span>
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<pre>/Users/gl/anaconda3/lib/python3.6/site-packages/ipykernel_launcher.py:12: RuntimeWarning: divide by zero encountered in log2
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<div class="prompt input_prompt">In&nbsp;[17]:</div>
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<div class=" highlight hl-ipython3"><pre><span></span><span class="c1">#df_vals = df_vals[~df_vals[&#39;education&#39;].isnull()] </span>
<span class="n">dd</span><span class="o">=</span><span class="n">dd</span><span class="p">[</span><span class="o">~</span><span class="n">dd</span><span class="p">[</span><span class="s2">&quot;Kinase&quot;</span><span class="p">]</span><span class="o">.</span><span class="n">isnull</span><span class="p">()]</span>  <span class="c1">#user define CV value: Rows Above CV_P filtered out </span>

<span class="n">dd</span>
<span class="c1">#dd.to_csv(&quot;nonankinase.csv&quot;)</span>
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<table border="1" class="dataframe">
  <thead>
    <tr style="text-align: right;">
      <th></th>
      <th>Substrate</th>
      <th>Control_mean</th>
      <th>Inhibitor_mean</th>
      <th>Fold_change</th>
      <th>p_value</th>
      <th>ctrlCV</th>
      <th>treatCV</th>
      <th>Phosphosite</th>
      <th>Sub_gene</th>
      <th>Kinase</th>
      <th>color</th>
      <th>log_pvalue</th>
      <th>log_FC</th>
    </tr>
  </thead>
  <tbody>
    <tr>
      <th>8</th>
      <td>AAK1</td>
      <td>3.220931e+08</td>
      <td>2.678659e+08</td>
      <td>0.831641</td>
      <td>0.572706</td>
      <td>0.339347</td>
      <td>0.423268</td>
      <td>T389</td>
      <td>AAK1</td>
      <td>CDK1</td>
      <td>grey</td>
      <td>0.242068</td>
      <td>-0.265967</td>
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    <tr>
      <th>23</th>
      <td>ABCF1</td>
      <td>3.729907e+09</td>
      <td>5.887469e+09</td>
      <td>1.578449</td>
      <td>0.024749</td>
      <td>0.184789</td>
      <td>0.178244</td>
      <td>S109</td>
      <td>ABCF1</td>
      <td>CK2A1</td>
      <td>green</td>
      <td>1.606443</td>
      <td>0.658508</td>
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    <tr>
      <th>24</th>
      <td>ABCF1</td>
      <td>5.130510e+09</td>
      <td>3.859859e+09</td>
      <td>0.752334</td>
      <td>0.171288</td>
      <td>0.209021</td>
      <td>0.239829</td>
      <td>S140</td>
      <td>ABCF1</td>
      <td>CK2A1</td>
      <td>grey</td>
      <td>0.766272</td>
      <td>-0.410554</td>
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    <tr>
      <th>29</th>
      <td>ABI1</td>
      <td>6.954255e+09</td>
      <td>8.002003e+09</td>
      <td>1.150663</td>
      <td>0.274058</td>
      <td>0.131522</td>
      <td>0.149789</td>
      <td>S183</td>
      <td>ABI1</td>
      <td>ERK1</td>
      <td>grey</td>
      <td>0.562157</td>
      <td>0.202465</td>
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    <tr>
      <th>30</th>
      <td>ABI1</td>
      <td>6.954255e+09</td>
      <td>8.002003e+09</td>
      <td>1.150663</td>
      <td>0.274058</td>
      <td>0.131522</td>
      <td>0.149789</td>
      <td>S183</td>
      <td>ABI1</td>
      <td>ERK2</td>
      <td>grey</td>
      <td>0.562157</td>
      <td>0.202465</td>
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      <th>34</th>
      <td>ABI1</td>
      <td>3.553320e+08</td>
      <td>4.794626e+08</td>
      <td>1.349337</td>
      <td>0.121853</td>
      <td>0.043769</td>
      <td>0.246919</td>
      <td>Y213</td>
      <td>ABI1</td>
      <td>Abl</td>
      <td>grey</td>
      <td>0.914164</td>
      <td>0.432251</td>
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      <th>54</th>
      <td>ACACA</td>
      <td>9.367416e+08</td>
      <td>1.819075e+09</td>
      <td>1.941918</td>
      <td>0.006910</td>
      <td>0.140979</td>
      <td>0.195626</td>
      <td>S80</td>
      <td>ACACA</td>
      <td>AMPKA1</td>
      <td>green</td>
      <td>2.160533</td>
      <td>0.957482</td>
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    <tr>
      <th>55</th>
      <td>ACACA</td>
      <td>9.367416e+08</td>
      <td>1.819075e+09</td>
      <td>1.941918</td>
      <td>0.006910</td>
      <td>0.140979</td>
      <td>0.195626</td>
      <td>S80</td>
      <td>ACACA</td>
      <td>AMPKA2</td>
      <td>green</td>
      <td>2.160533</td>
      <td>0.957482</td>
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      <th>113</th>
      <td>ADD1</td>
      <td>3.122984e+07</td>
      <td>5.593549e+07</td>
      <td>1.791091</td>
      <td>0.446615</td>
      <td>1.001082</td>
      <td>0.755225</td>
      <td>S12</td>
      <td>ADD1</td>
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      <td>grey</td>
      <td>0.350066</td>
      <td>0.840839</td>
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      <th>119</th>
      <td>ADD1</td>
      <td>1.332489e+07</td>
      <td>1.949857e+07</td>
      <td>1.463319</td>
      <td>0.641231</td>
      <td>0.726807</td>
      <td>1.001791</td>
      <td>S726</td>
      <td>ADD1</td>
      <td>PKCD</td>
      <td>grey</td>
      <td>0.192985</td>
      <td>0.549244</td>
    </tr>
    <tr>
      <th>120</th>
      <td>ADD1</td>
      <td>1.332489e+07</td>
      <td>1.949857e+07</td>
      <td>1.463319</td>
      <td>0.641231</td>
      <td>0.726807</td>
      <td>1.001791</td>
      <td>S726</td>
      <td>ADD1</td>
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      <td>grey</td>
      <td>0.192985</td>
      <td>0.549244</td>
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    <tr>
      <th>121</th>
      <td>ADD1</td>
      <td>1.332489e+07</td>
      <td>1.949857e+07</td>
      <td>1.463319</td>
      <td>0.641231</td>
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      <td>ADD1</td>
      <td>PKCA</td>
      <td>grey</td>
      <td>0.192985</td>
      <td>0.549244</td>
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    <tr>
      <th>122</th>
      <td>ADD1</td>
      <td>1.332489e+07</td>
      <td>1.949857e+07</td>
      <td>1.463319</td>
      <td>0.641231</td>
      <td>0.726807</td>
      <td>1.001791</td>
      <td>S726</td>
      <td>ADD1</td>
      <td>PKCZ</td>
      <td>grey</td>
      <td>0.192985</td>
      <td>0.549244</td>
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    <tr>
      <th>127</th>
      <td>ADD2</td>
      <td>1.747978e+09</td>
      <td>3.721304e+08</td>
      <td>0.212892</td>
      <td>0.007357</td>
      <td>0.312763</td>
      <td>0.664823</td>
      <td>S613</td>
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      <td>GSK3B</td>
      <td>red</td>
      <td>2.133321</td>
      <td>-2.231807</td>
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    <tr>
      <th>129</th>
      <td>ADD2</td>
      <td>4.655196e+08</td>
      <td>4.234087e+08</td>
      <td>0.909540</td>
      <td>0.928164</td>
      <td>1.435194</td>
      <td>0.931672</td>
      <td>S701</td>
      <td>ADD2</td>
      <td>CDK5</td>
      <td>grey</td>
      <td>0.032375</td>
      <td>-0.136791</td>
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      <th>130</th>
      <td>ADD3</td>
      <td>0.000000e+00</td>
      <td>0.000000e+00</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>S42</td>
      <td>ADD3</td>
      <td>CDK2</td>
      <td>grey</td>
      <td>NaN</td>
      <td>NaN</td>
    </tr>
    <tr>
      <th>132</th>
      <td>ADD3</td>
      <td>4.823210e+09</td>
      <td>5.171387e+09</td>
      <td>1.072188</td>
      <td>0.487553</td>
      <td>0.073165</td>
      <td>0.142181</td>
      <td>S693</td>
      <td>ADD3</td>
      <td>Chk1</td>
      <td>grey</td>
      <td>0.311978</td>
      <td>0.100558</td>
    </tr>
    <tr>
      <th>194</th>
      <td>AGO2</td>
      <td>7.351497e+08</td>
      <td>5.564733e+08</td>
      <td>0.756952</td>
      <td>0.100504</td>
      <td>0.172695</td>
      <td>0.173687</td>
      <td>S387</td>
      <td>AGO2</td>
      <td>MAPKAPK2</td>
      <td>grey</td>
      <td>0.997816</td>
      <td>-0.401726</td>
    </tr>
    <tr>
      <th>195</th>
      <td>AGO2</td>
      <td>7.351497e+08</td>
      <td>5.564733e+08</td>
      <td>0.756952</td>
      <td>0.100504</td>
      <td>0.172695</td>
      <td>0.173687</td>
      <td>S387</td>
      <td>AGO2</td>
      <td>Akt3</td>
      <td>grey</td>
      <td>0.997816</td>
      <td>-0.401726</td>
    </tr>
    <tr>
      <th>257</th>
      <td>AIMP1</td>
      <td>0.000000e+00</td>
      <td>0.000000e+00</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>S140</td>
      <td>AIMP1</td>
      <td>JNK1</td>
      <td>grey</td>
      <td>NaN</td>
      <td>NaN</td>
    </tr>
    <tr>
      <th>259</th>
      <td>AJUBA</td>
      <td>1.585271e+09</td>
      <td>1.362069e+09</td>
      <td>0.859203</td>
      <td>0.227568</td>
      <td>0.062152</td>
      <td>0.198425</td>
      <td>S119</td>
      <td>AJUBA</td>
      <td>CDK1</td>
      <td>grey</td>
      <td>0.642888</td>
      <td>-0.218930</td>
    </tr>
    <tr>
      <th>291</th>
      <td>AKAP12</td>
      <td>1.408803e+08</td>
      <td>7.187235e+08</td>
      <td>5.101659</td>
      <td>0.127881</td>
      <td>0.651484</td>
      <td>0.778252</td>
      <td>S627</td>
      <td>AKAP12</td>
      <td>PKACA</td>
      <td>grey</td>
      <td>0.893195</td>
      <td>2.350967</td>
    </tr>
    <tr>
      <th>293</th>
      <td>AKAP12</td>
      <td>0.000000e+00</td>
      <td>0.000000e+00</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>S696</td>
      <td>AKAP12</td>
      <td>PKACA</td>
      <td>grey</td>
      <td>NaN</td>
      <td>NaN</td>
    </tr>
    <tr>
      <th>295</th>
      <td>AKAP12</td>
      <td>0.000000e+00</td>
      <td>0.000000e+00</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>S698</td>
      <td>AKAP12</td>
      <td>PKACA</td>
      <td>grey</td>
      <td>NaN</td>
      <td>NaN</td>
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    <tr>
      <th>297</th>
      <td>AKAP12</td>
      <td>7.799472e+08</td>
      <td>8.798277e+08</td>
      <td>1.128061</td>
      <td>0.218834</td>
      <td>0.122885</td>
      <td>0.092953</td>
      <td>T767</td>
      <td>AKAP12</td>
      <td>CDK1</td>
      <td>grey</td>
      <td>0.659884</td>
      <td>0.173845</td>
    </tr>
    <tr>
      <th>300</th>
      <td>AKAP13</td>
      <td>6.066856e+08</td>
      <td>5.866112e+08</td>
      <td>0.966911</td>
      <td>0.878155</td>
      <td>0.095552</td>
      <td>0.357103</td>
      <td>S1565</td>
      <td>AKAP13</td>
      <td>PKACA</td>
      <td>grey</td>
      <td>0.056429</td>
      <td>-0.048544</td>
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    <tr>
      <th>327</th>
      <td>AKIRIN2</td>
      <td>1.909108e+08</td>
      <td>3.181032e+08</td>
      <td>1.666240</td>
      <td>0.023345</td>
      <td>0.322419</td>
      <td>0.122824</td>
      <td>S18</td>
      <td>AKIRIN2</td>
      <td>CDK2</td>
      <td>green</td>
      <td>1.631812</td>
      <td>0.736597</td>
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    <tr>
      <th>328</th>
      <td>AKIRIN2</td>
      <td>4.528564e+08</td>
      <td>5.791934e+08</td>
      <td>1.278978</td>
      <td>0.063204</td>
      <td>0.090704</td>
      <td>0.150137</td>
      <td>S21</td>
      <td>AKIRIN2</td>
      <td>CDK2</td>
      <td>grey</td>
      <td>1.199257</td>
      <td>0.354991</td>
    </tr>
    <tr>
      <th>333</th>
      <td>AKT1</td>
      <td>3.132603e+09</td>
      <td>5.156830e+09</td>
      <td>1.646181</td>
      <td>0.179509</td>
      <td>0.317100</td>
      <td>0.403941</td>
      <td>S129</td>
      <td>AKT1</td>
      <td>CK2A1</td>
      <td>grey</td>
      <td>0.745914</td>
      <td>0.719123</td>
    </tr>
    <tr>
      <th>334</th>
      <td>AKT1</td>
      <td>5.158378e+08</td>
      <td>2.204069e+08</td>
      <td>0.427279</td>
      <td>0.222719</td>
      <td>0.602235</td>
      <td>0.963148</td>
      <td>S473</td>
      <td>AKT1</td>
      <td>TBK1</td>
      <td>grey</td>
      <td>0.652242</td>
      <td>-1.226748</td>
    </tr>
    <tr>
      <th>335</th>
      <td>AKT1</td>
      <td>5.158378e+08</td>
      <td>2.204069e+08</td>
      <td>0.427279</td>
      <td>0.222719</td>
      <td>0.602235</td>
      <td>0.963148</td>
      <td>S473</td>
      <td>AKT1</td>
      <td>MAPKAPK2</td>
      <td>grey</td>
      <td>0.652242</td>
      <td>-1.226748</td>
    </tr>
    <tr>
      <th>336</th>
      <td>AKT1</td>
      <td>5.158378e+08</td>
      <td>2.204069e+08</td>
      <td>0.427279</td>
      <td>0.222719</td>
      <td>0.602235</td>
      <td>0.963148</td>
      <td>S473</td>
      <td>AKT1</td>
      <td>ILK</td>
      <td>grey</td>
      <td>0.652242</td>
      <td>-1.226748</td>
    </tr>
    <tr>
      <th>337</th>
      <td>AKT1</td>
      <td>5.158378e+08</td>
      <td>2.204069e+08</td>
      <td>0.427279</td>
      <td>0.222719</td>
      <td>0.602235</td>
      <td>0.963148</td>
      <td>S473</td>
      <td>AKT1</td>
      <td>DNAPK</td>
      <td>grey</td>
      <td>0.652242</td>
      <td>-1.226748</td>
    </tr>
    <tr>
      <th>338</th>
      <td>AKT1</td>
      <td>5.158378e+08</td>
      <td>2.204069e+08</td>
      <td>0.427279</td>
      <td>0.222719</td>
      <td>0.602235</td>
      <td>0.963148</td>
      <td>S473</td>
      <td>AKT1</td>
      <td>PIKFYVE</td>
      <td>grey</td>
      <td>0.652242</td>
      <td>-1.226748</td>
    </tr>
    <tr>
      <th>339</th>
      <td>AKT1</td>
      <td>5.158378e+08</td>
      <td>2.204069e+08</td>
      <td>0.427279</td>
      <td>0.222719</td>
      <td>0.602235</td>
      <td>0.963148</td>
      <td>S473</td>
      <td>AKT1</td>
      <td>PRKD1</td>
      <td>grey</td>
      <td>0.652242</td>
      <td>-1.226748</td>
    </tr>
    <tr>
      <th>340</th>
      <td>AKT1</td>
      <td>5.158378e+08</td>
      <td>2.204069e+08</td>
      <td>0.427279</td>
      <td>0.222719</td>
      <td>0.602235</td>
      <td>0.963148</td>
      <td>S473</td>
      <td>AKT1</td>
      <td>IKKE</td>
      <td>grey</td>
      <td>0.652242</td>
      <td>-1.226748</td>
    </tr>
    <tr>
      <th>341</th>
      <td>AKT1</td>
      <td>5.158378e+08</td>
      <td>2.204069e+08</td>
      <td>0.427279</td>
      <td>0.222719</td>
      <td>0.602235</td>
      <td>0.963148</td>
      <td>S473</td>
      <td>AKT1</td>
      <td>PDK1</td>
      <td>grey</td>
      <td>0.652242</td>
      <td>-1.226748</td>
    </tr>
    <tr>
      <th>342</th>
      <td>AKT1</td>
      <td>5.158378e+08</td>
      <td>2.204069e+08</td>
      <td>0.427279</td>
      <td>0.222719</td>
      <td>0.602235</td>
      <td>0.963148</td>
      <td>S473</td>
      <td>AKT1</td>
      <td>LRRK2</td>
      <td>grey</td>
      <td>0.652242</td>
      <td>-1.226748</td>
    </tr>
    <tr>
      <th>343</th>
      <td>AKT1</td>
      <td>5.158378e+08</td>
      <td>2.204069e+08</td>
      <td>0.427279</td>
      <td>0.222719</td>
      <td>0.602235</td>
      <td>0.963148</td>
      <td>S473</td>
      <td>AKT1</td>
      <td>mTOR</td>
      <td>grey</td>
      <td>0.652242</td>
      <td>-1.226748</td>
    </tr>
    <tr>
      <th>344</th>
      <td>AKT1</td>
      <td>5.158378e+08</td>
      <td>2.204069e+08</td>
      <td>0.427279</td>
      <td>0.222719</td>
      <td>0.602235</td>
      <td>0.963148</td>
      <td>S473</td>
      <td>AKT1</td>
      <td>Mer</td>
      <td>grey</td>
      <td>0.652242</td>
      <td>-1.226748</td>
    </tr>
    <tr>
      <th>345</th>
      <td>AKT1</td>
      <td>5.158378e+08</td>
      <td>2.204069e+08</td>
      <td>0.427279</td>
      <td>0.222719</td>
      <td>0.602235</td>
      <td>0.963148</td>
      <td>S473</td>
      <td>AKT1</td>
      <td>PKCA</td>
      <td>grey</td>
      <td>0.652242</td>
      <td>-1.226748</td>
    </tr>
    <tr>
      <th>346</th>
      <td>AKT1</td>
      <td>5.158378e+08</td>
      <td>2.204069e+08</td>
      <td>0.427279</td>
      <td>0.222719</td>
      <td>0.602235</td>
      <td>0.963148</td>
      <td>S473</td>
      <td>AKT1</td>
      <td>PKCB</td>
      <td>grey</td>
      <td>0.652242</td>
      <td>-1.226748</td>
    </tr>
    <tr>
      <th>347</th>
      <td>AKT1</td>
      <td>5.158378e+08</td>
      <td>2.204069e+08</td>
      <td>0.427279</td>
      <td>0.222719</td>
      <td>0.602235</td>
      <td>0.963148</td>
      <td>S473</td>
      <td>AKT1</td>
      <td>AXL</td>
      <td>grey</td>
      <td>0.652242</td>
      <td>-1.226748</td>
    </tr>
    <tr>
      <th>348</th>
      <td>AKT1</td>
      <td>0.000000e+00</td>
      <td>0.000000e+00</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>T312</td>
      <td>AKT1</td>
      <td>GSK3A</td>
      <td>grey</td>
      <td>NaN</td>
      <td>NaN</td>
    </tr>
    <tr>
      <th>350</th>
      <td>AKT1</td>
      <td>0.000000e+00</td>
      <td>0.000000e+00</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>T450</td>
      <td>AKT1</td>
      <td>mTOR</td>
      <td>grey</td>
      <td>NaN</td>
      <td>NaN</td>
    </tr>
    <tr>
      <th>351</th>
      <td>AKT1S1</td>
      <td>6.105962e+08</td>
      <td>2.176100e+08</td>
      <td>0.356389</td>
      <td>0.008361</td>
      <td>0.284972</td>
      <td>0.131286</td>
      <td>S183</td>
      <td>AKT1S1</td>
      <td>mTOR</td>
      <td>red</td>
      <td>2.077753</td>
      <td>-1.488474</td>
    </tr>
    <tr>
      <th>352</th>
      <td>AKT1S1</td>
      <td>6.457577e+07</td>
      <td>4.417949e+07</td>
      <td>0.684150</td>
      <td>0.603906</td>
      <td>0.941097</td>
      <td>0.492271</td>
      <td>S203</td>
      <td>AKT1S1</td>
      <td>PKM</td>
      <td>grey</td>
      <td>0.219031</td>
      <td>-0.547616</td>
    </tr>
    <tr>
      <th>389</th>
      <td>AMOTL2</td>
      <td>3.350480e+08</td>
      <td>4.094197e+08</td>
      <td>1.221973</td>
      <td>0.337128</td>
      <td>0.195167</td>
      <td>0.255900</td>
      <td>S759</td>
      <td>AMOTL2</td>
      <td>mTOR</td>
      <td>grey</td>
      <td>0.472205</td>
      <td>0.289213</td>
    </tr>
    <tr>
      <th>397</th>
      <td>AMPH</td>
      <td>0.000000e+00</td>
      <td>0.000000e+00</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>S272</td>
      <td>AMPH</td>
      <td>CDK1</td>
      <td>grey</td>
      <td>NaN</td>
      <td>NaN</td>
    </tr>
    <tr>
      <th>398</th>
      <td>AMPH</td>
      <td>0.000000e+00</td>
      <td>0.000000e+00</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>NaN</td>
      <td>S272</td>
      <td>AMPH</td>
      <td>CDK5</td>
      <td>grey</td>
      <td>NaN</td>
      <td>NaN</td>
    </tr>
    <tr>
      <th>401</th>
      <td>ANAPC1</td>
      <td>2.308922e+08</td>
      <td>3.231128e+08</td>
      <td>1.399410</td>
      <td>0.011624</td>
      <td>0.133089</td>
      <td>0.100042</td>
      <td>S355</td>
      <td>ANAPC1</td>
      <td>CDK1</td>
      <td>green</td>
      <td>1.934655</td>
      <td>0.484818</td>
    </tr>
    <tr>
      <th>402</th>
      <td>ANAPC1</td>
      <td>2.308922e+08</td>
      <td>3.231128e+08</td>
      <td>1.399410</td>
      <td>0.011624</td>
      <td>0.133089</td>
      <td>0.100042</td>
      <td>S355</td>
      <td>ANAPC1</td>
      <td>PLK1</td>
      <td>green</td>
      <td>1.934655</td>
      <td>0.484818</td>
    </tr>
    <tr>
      <th>403</th>
      <td>ANAPC1</td>
      <td>2.688357e+08</td>
      <td>5.950942e+08</td>
      <td>2.213598</td>
      <td>0.033918</td>
      <td>0.546590</td>
      <td>0.243914</td>
      <td>S377</td>
      <td>ANAPC1</td>
      <td>CDK1</td>
      <td>green</td>
      <td>1.469570</td>
      <td>1.146393</td>
    </tr>
    <tr>
      <th>404</th>
      <td>ANAPC1</td>
      <td>2.688357e+08</td>
      <td>5.950942e+08</td>
      <td>2.213598</td>
      <td>0.033918</td>
      <td>0.546590</td>
      <td>0.243914</td>
      <td>S377</td>
      <td>ANAPC1</td>
      <td>PLK1</td>
      <td>green</td>
      <td>1.469570</td>
      <td>1.146393</td>
    </tr>
    <tr>
      <th>405</th>
      <td>ANAPC1</td>
      <td>7.512439e+06</td>
      <td>1.910890e+07</td>
      <td>2.543635</td>
      <td>0.381632</td>
      <td>1.230884</td>
      <td>1.002874</td>
      <td>S688</td>
      <td>ANAPC1</td>
      <td>CDK1</td>
      <td>grey</td>
      <td>0.418355</td>
      <td>1.346892</td>
    </tr>
    <tr>
      <th>406</th>
      <td>ANAPC1</td>
      <td>7.512439e+06</td>
      <td>1.910890e+07</td>
      <td>2.543635</td>
      <td>0.381632</td>
      <td>1.230884</td>
      <td>1.002874</td>
      <td>S688</td>
      <td>ANAPC1</td>
      <td>PLK1</td>
      <td>grey</td>
      <td>0.418355</td>
      <td>1.346892</td>
    </tr>
    <tr>
      <th>410</th>
      <td>ANAPC4</td>
      <td>0.000000e+00</td>
      <td>2.102920e+07</td>
      <td>NaN</td>
      <td>0.083486</td>
      <td>NaN</td>
      <td>0.835342</td>
      <td>S779</td>
      <td>ANAPC4</td>
      <td>CDK1</td>
      <td>grey</td>
      <td>1.078384</td>
      <td>NaN</td>
    </tr>
    <tr>
      <th>411</th>
      <td>ANAPC4</td>
      <td>0.000000e+00</td>
      <td>2.102920e+07</td>
      <td>NaN</td>
      <td>0.083486</td>
      <td>NaN</td>
      <td>0.835342</td>
      <td>S779</td>
      <td>ANAPC4</td>
      <td>PLK1</td>
      <td>grey</td>
      <td>1.078384</td>
      <td>NaN</td>
    </tr>
  </tbody>
</table>
</div>
</div>

</div>

</div>
</div>

</div>
<div class="cell border-box-sizing code_cell rendered">
<div class="input">
<div class="prompt input_prompt">In&nbsp;[18]:</div>
<div class="inner_cell">
    <div class="input_area">
<div class=" highlight hl-ipython3"><pre><span></span><span class="k">def</span> <span class="nf">makeplot_2</span><span class="p">(</span><span class="n">df</span><span class="p">,</span> <span class="n">FC_P</span><span class="p">,</span> <span class="n">PV_P</span><span class="p">,</span> <span class="n">Inhibitor</span><span class="p">):</span>
    
   
    <span class="n">df</span><span class="o">.</span><span class="n">loc</span><span class="p">[(</span><span class="n">df</span><span class="p">[</span><span class="s1">&#39;Fold_change&#39;</span><span class="p">]</span> <span class="o">&gt;</span> <span class="n">FC_P</span><span class="p">)</span> <span class="o">&amp;</span> <span class="p">(</span><span class="n">df</span><span class="p">[</span><span class="s1">&#39;p_value&#39;</span><span class="p">]</span> <span class="o">&lt;</span> <span class="n">PV_P</span><span class="p">),</span> <span class="s1">&#39;color&#39;</span> <span class="p">]</span> <span class="o">=</span> <span class="s2">&quot;Blue&quot;</span>  <span class="c1"># upregulated</span>
    <span class="c1">#df.loc - Selects single row or subset of rows from the DataFrame by label</span>
    <span class="n">df</span><span class="o">.</span><span class="n">loc</span><span class="p">[(</span><span class="n">df</span><span class="p">[</span><span class="s1">&#39;Fold_change&#39;</span><span class="p">]</span> <span class="o">&lt;=</span><span class="n">FC_P</span><span class="p">)</span> <span class="o">&amp;</span> <span class="p">(</span><span class="n">df</span><span class="p">[</span><span class="s1">&#39;p_value&#39;</span><span class="p">]</span> <span class="o">&lt;</span> <span class="n">PV_P</span><span class="p">),</span> <span class="s1">&#39;color&#39;</span> <span class="p">]</span> <span class="o">=</span> <span class="s2">&quot;Purple&quot;</span>   <span class="c1"># downregulated</span>
    <span class="n">df</span><span class="p">[</span><span class="s1">&#39;color&#39;</span><span class="p">]</span><span class="o">.</span><span class="n">fillna</span><span class="p">(</span><span class="s1">&#39;grey&#39;</span><span class="p">,</span> <span class="n">inplace</span><span class="o">=</span><span class="kc">True</span><span class="p">)</span>
    

    <span class="n">df</span><span class="p">[</span><span class="s2">&quot;log_pvalue&quot;</span><span class="p">]</span> <span class="o">=</span> <span class="o">-</span><span class="n">np</span><span class="o">.</span><span class="n">log10</span><span class="p">(</span><span class="n">df</span><span class="p">[</span><span class="s1">&#39;p_value&#39;</span><span class="p">])</span>
    <span class="n">df</span><span class="p">[</span><span class="s2">&quot;log_FC&quot;</span><span class="p">]</span><span class="o">=</span><span class="n">np</span><span class="o">.</span><span class="n">log2</span><span class="p">(</span><span class="n">df</span><span class="p">[</span><span class="s1">&#39;Fold_change&#39;</span><span class="p">])</span>

    <span class="n">df</span><span class="o">.</span><span class="n">head</span><span class="p">()</span>


    <span class="kn">from</span> <span class="nn">bokeh.plotting</span> <span class="k">import</span> <span class="n">figure</span><span class="p">,</span> <span class="n">ColumnDataSource</span><span class="p">,</span> <span class="n">output_notebook</span><span class="p">,</span> <span class="n">show</span>
    <span class="kn">from</span> <span class="nn">bokeh.models</span> <span class="k">import</span> <span class="n">HoverTool</span><span class="p">,</span> <span class="n">WheelZoomTool</span><span class="p">,</span> <span class="n">PanTool</span><span class="p">,</span> <span class="n">BoxZoomTool</span><span class="p">,</span> <span class="n">ResetTool</span><span class="p">,</span> <span class="n">TapTool</span><span class="p">,</span> <span class="n">SaveTool</span>
    <span class="kn">from</span> <span class="nn">bokeh.palettes</span> <span class="k">import</span> <span class="n">brewer</span>


    <span class="n">output_notebook</span><span class="p">()</span>


    <span class="n">category</span> <span class="o">=</span> <span class="s1">&#39;Substrate&#39;</span>

    <span class="n">category_items</span> <span class="o">=</span> <span class="n">df</span><span class="p">[</span><span class="n">category</span><span class="p">]</span><span class="o">.</span><span class="n">unique</span><span class="p">()</span>

    <span class="n">title</span> <span class="o">=</span> <span class="n">Inhibitor</span> <span class="o">+</span> <span class="s2">&quot; :Data with identified kinases&quot;</span>
    <span class="c1">#feeding data into ColumnDataSource</span>
    <span class="n">source</span> <span class="o">=</span> <span class="n">ColumnDataSource</span><span class="p">(</span><span class="n">df</span><span class="p">)</span>
    <span class="c1">#Editing the hover that need to displayed while hovering</span>
    <span class="n">hover</span> <span class="o">=</span> <span class="n">HoverTool</span><span class="p">(</span><span class="n">tooltips</span><span class="o">=</span><span class="p">[(</span><span class="s1">&#39;Kinase&#39;</span><span class="p">,</span><span class="s1">&#39;@Kinase&#39;</span><span class="p">),</span>
                                <span class="p">(</span><span class="s1">&#39;Substrate&#39;</span><span class="p">,</span> <span class="s1">&#39;@Substrate&#39;</span><span class="p">),</span>
                                <span class="p">(</span><span class="s1">&#39;Sub_gene&#39;</span><span class="p">,</span><span class="s1">&#39;@Sub_gene&#39;</span><span class="p">),</span>
                                <span class="p">(</span><span class="s1">&#39;Phosphosite&#39;</span><span class="p">,</span> <span class="s1">&#39;@Phosphosite&#39;</span><span class="p">),</span>
                               <span class="p">(</span><span class="s1">&#39;Fold_change&#39;</span><span class="p">,</span> <span class="s1">&#39;@Fold_change&#39;</span><span class="p">),</span>
                               <span class="p">(</span><span class="s1">&#39;p_value&#39;</span><span class="p">,</span> <span class="s1">&#39;@p_value&#39;</span><span class="p">)])</span>
    <span class="c1">#tools that are need to explote data</span>
    <span class="n">tools</span> <span class="o">=</span> <span class="p">[</span><span class="n">hover</span><span class="p">,</span> <span class="n">WheelZoomTool</span><span class="p">(),</span> <span class="n">PanTool</span><span class="p">(),</span> <span class="n">BoxZoomTool</span><span class="p">(),</span> <span class="n">ResetTool</span><span class="p">(),</span> <span class="n">SaveTool</span><span class="p">()]</span>
    

    <span class="c1">#finally making figure with scatter plot</span>
    <span class="n">p</span> <span class="o">=</span> <span class="n">figure</span><span class="p">(</span><span class="n">tools</span><span class="o">=</span><span class="n">tools</span><span class="p">,</span><span class="n">title</span><span class="o">=</span><span class="n">title</span><span class="p">,</span><span class="n">plot_width</span><span class="o">=</span><span class="mi">700</span><span class="p">,</span><span class="n">plot_height</span><span class="o">=</span><span class="mi">400</span><span class="p">,</span><span class="n">toolbar_location</span><span class="o">=</span><span class="s1">&#39;right&#39;</span><span class="p">,</span><span class="n">toolbar_sticky</span><span class="o">=</span><span class="kc">False</span><span class="p">,</span> <span class="p">)</span>
   
    <span class="n">p</span><span class="o">.</span><span class="n">scatter</span><span class="p">(</span><span class="n">x</span><span class="o">=</span><span class="s1">&#39;log_FC&#39;</span><span class="p">,</span><span class="n">y</span><span class="o">=</span><span class="s1">&#39;log_pvalue&#39;</span><span class="p">,</span><span class="n">source</span><span class="o">=</span><span class="n">source</span><span class="p">,</span><span class="n">size</span><span class="o">=</span><span class="mi">10</span><span class="p">,</span><span class="n">color</span><span class="o">=</span><span class="s1">&#39;color&#39;</span><span class="p">)</span>
    
    <span class="c1">#displaying the graph</span>
    <span class="n">show</span><span class="p">(</span><span class="n">p</span><span class="p">)</span>
    
<span class="n">makeplot_2</span><span class="p">(</span><span class="n">dd</span><span class="p">,</span> <span class="mf">1.0</span><span class="p">,</span> <span class="mf">0.05</span><span class="p">,</span> <span class="s2">&quot;AZ20&quot;</span><span class="p">)</span>
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<div class="prompt input_prompt">In&nbsp;[19]:</div>
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<div class=" highlight hl-ipython3"><pre><span></span><span class="c1">##########</span>
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<div class=" highlight hl-ipython3"><pre><span></span><span class="c1">###Sum of control_mean and inhibitor_mean </span>

<span class="c1">#=control mean</span>
<span class="n">kinase_sum_control_mean</span><span class="o">=</span> <span class="n">dd</span><span class="o">.</span><span class="n">groupby</span><span class="p">(</span><span class="s2">&quot;Kinase&quot;</span><span class="p">)</span><span class="o">.</span><span class="n">Control_mean</span><span class="o">.</span><span class="n">sum</span><span class="p">()</span> <span class="c1">#sum of individual group of kinases at a phosphosite</span>
<span class="c1">#kinase_sum_control_mean</span>
<span class="n">total_control_mean_sum</span><span class="o">=</span><span class="n">dd</span><span class="o">.</span><span class="n">Control_mean</span><span class="o">.</span><span class="n">sum</span><span class="p">()</span>  <span class="c1">#toal sum of control_mean of all kinases</span>

<span class="n">dkinase</span><span class="o">=</span><span class="n">pd</span><span class="o">.</span><span class="n">DataFrame</span><span class="p">(</span><span class="n">kinase_sum_control_mean</span><span class="p">)</span>
<span class="n">dkinase</span><span class="p">[</span><span class="s2">&quot;relative_control_activity&quot;</span><span class="p">]</span><span class="o">=</span><span class="n">dkinase</span><span class="p">[</span><span class="s2">&quot;Control_mean&quot;</span><span class="p">]</span><span class="o">/</span><span class="n">total_control_mean_sum</span>

<span class="c1">#relative activity = mean of each kinase/total control means</span>


<span class="c1">#-------------</span>
<span class="c1">#inhibitor mean</span>
<span class="n">kinase_sum_inhibitor_mean</span><span class="o">=</span> <span class="n">dd</span><span class="o">.</span><span class="n">groupby</span><span class="p">(</span><span class="s2">&quot;Kinase&quot;</span><span class="p">)</span><span class="o">.</span><span class="n">Inhibitor_mean</span><span class="o">.</span><span class="n">sum</span><span class="p">()</span> <span class="c1">#sum of groups of kinases</span>
<span class="n">dkinase</span><span class="p">[</span><span class="s2">&quot;Inhibitor_mean&quot;</span><span class="p">]</span><span class="o">=</span><span class="n">kinase_sum_inhibitor_mean</span>

<span class="n">total_inhibitor_mean</span><span class="o">=</span><span class="n">dd</span><span class="o">.</span><span class="n">Inhibitor_mean</span><span class="o">.</span><span class="n">sum</span><span class="p">()</span>
<span class="n">dkinase</span><span class="p">[</span><span class="s2">&quot;relative_inhibitor_activity&quot;</span><span class="p">]</span><span class="o">=</span><span class="n">dkinase</span><span class="p">[</span><span class="s2">&quot;Inhibitor_mean&quot;</span><span class="p">]</span><span class="o">/</span><span class="n">total_inhibitor_mean</span>

<span class="c1"># #Mean Fold Change</span>
<span class="n">dkinase</span><span class="p">[</span><span class="s2">&quot;mean_FC_kinase&quot;</span><span class="p">]</span><span class="o">=</span> <span class="n">dkinase</span><span class="p">[</span><span class="s2">&quot;Inhibitor_mean&quot;</span><span class="p">]</span><span class="o">/</span><span class="n">dkinase</span><span class="p">[</span><span class="s2">&quot;Control_mean&quot;</span><span class="p">]</span>
<span class="c1"># #----------------</span>
<span class="n">dkinase</span><span class="o">.</span><span class="n">rename</span><span class="p">(</span><span class="n">columns</span><span class="o">=</span><span class="p">{</span><span class="n">dkinase</span><span class="o">.</span><span class="n">columns</span><span class="p">[</span><span class="mi">0</span><span class="p">]:</span> <span class="s2">&quot;total_control_mean&quot;</span><span class="p">},</span> <span class="n">inplace</span><span class="o">=</span><span class="kc">True</span><span class="p">)</span>
<span class="n">dkinase</span><span class="o">.</span><span class="n">rename</span><span class="p">(</span><span class="n">columns</span><span class="o">=</span><span class="p">{</span><span class="n">dkinase</span><span class="o">.</span><span class="n">columns</span><span class="p">[</span><span class="mi">2</span><span class="p">]:</span> <span class="s2">&quot;total_inhibitor_mean&quot;</span><span class="p">},</span> <span class="n">inplace</span><span class="o">=</span><span class="kc">True</span><span class="p">)</span>
<span class="c1"># dkinase[&quot;relative_FC_kinase&quot;]= dkinase[&quot;relative_inhibitor_activity&quot;]/dkinase[&quot;relative_control_activity&quot;]</span>
<span class="n">dkinase</span>
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<table border="1" class="dataframe">
  <thead>
    <tr style="text-align: right;">
      <th></th>
      <th>total_control_mean</th>
      <th>relative_control_activity</th>
      <th>total_inhibitor_mean</th>
      <th>relative_inhibitor_activity</th>
      <th>mean_FC_kinase</th>
    </tr>
    <tr>
      <th>Kinase</th>
      <th></th>
      <th></th>
      <th></th>
      <th></th>
      <th></th>
    </tr>
  </thead>
  <tbody>
    <tr>
      <th>AMPKA1</th>
      <td>9.367416e+08</td>
      <td>0.018717</td>
      <td>1.819075e+09</td>
      <td>0.034566</td>
      <td>1.941918</td>
    </tr>
    <tr>
      <th>AMPKA2</th>
      <td>9.367416e+08</td>
      <td>0.018717</td>
      <td>1.819075e+09</td>
      <td>0.034566</td>
      <td>1.941918</td>
    </tr>
    <tr>
      <th>AXL</th>
      <td>5.158378e+08</td>
      <td>0.010307</td>
      <td>2.204069e+08</td>
      <td>0.004188</td>
      <td>0.427279</td>
    </tr>
    <tr>
      <th>Abl</th>
      <td>3.553320e+08</td>
      <td>0.007100</td>
      <td>4.794626e+08</td>
      <td>0.009111</td>
      <td>1.349337</td>
    </tr>
    <tr>
      <th>Akt3</th>
      <td>7.351497e+08</td>
      <td>0.014689</td>
      <td>5.564733e+08</td>
      <td>0.010574</td>
      <td>0.756952</td>
    </tr>
    <tr>
      <th>CDK1</th>
      <td>3.225782e+09</td>
      <td>0.064455</td>
      <td>3.524043e+09</td>
      <td>0.066964</td>
      <td>1.092462</td>
    </tr>
    <tr>
      <th>CDK2</th>
      <td>6.437672e+08</td>
      <td>0.012863</td>
      <td>8.972966e+08</td>
      <td>0.017051</td>
      <td>1.393822</td>
    </tr>
    <tr>
      <th>CDK5</th>
      <td>4.655196e+08</td>
      <td>0.009302</td>
      <td>4.234087e+08</td>
      <td>0.008046</td>
      <td>0.909540</td>
    </tr>
    <tr>
      <th>CK2A1</th>
      <td>1.199302e+10</td>
      <td>0.239635</td>
      <td>1.490416e+10</td>
      <td>0.283211</td>
      <td>1.242736</td>
    </tr>
    <tr>
      <th>Chk1</th>
      <td>4.836535e+09</td>
      <td>0.096640</td>
      <td>5.190886e+09</td>
      <td>0.098638</td>
      <td>1.073265</td>
    </tr>
    <tr>
      <th>DNAPK</th>
      <td>5.158378e+08</td>
      <td>0.010307</td>
      <td>2.204069e+08</td>
      <td>0.004188</td>
      <td>0.427279</td>
    </tr>
    <tr>
      <th>ERK1</th>
      <td>6.954255e+09</td>
      <td>0.138955</td>
      <td>8.002003e+09</td>
      <td>0.152055</td>
      <td>1.150663</td>
    </tr>
    <tr>
      <th>ERK2</th>
      <td>6.954255e+09</td>
      <td>0.138955</td>
      <td>8.002003e+09</td>
      <td>0.152055</td>
      <td>1.150663</td>
    </tr>
    <tr>
      <th>GSK3A</th>
      <td>0.000000e+00</td>
      <td>0.000000</td>
      <td>0.000000e+00</td>
      <td>0.000000</td>
      <td>NaN</td>
    </tr>
    <tr>
      <th>GSK3B</th>
      <td>1.747978e+09</td>
      <td>0.034927</td>
      <td>3.721304e+08</td>
      <td>0.007071</td>
      <td>0.212892</td>
    </tr>
    <tr>
      <th>IKKE</th>
      <td>5.158378e+08</td>
      <td>0.010307</td>
      <td>2.204069e+08</td>
      <td>0.004188</td>
      <td>0.427279</td>
    </tr>
    <tr>
      <th>ILK</th>
      <td>5.158378e+08</td>
      <td>0.010307</td>
      <td>2.204069e+08</td>
      <td>0.004188</td>
      <td>0.427279</td>
    </tr>
    <tr>
      <th>JNK1</th>
      <td>0.000000e+00</td>
      <td>0.000000</td>
      <td>0.000000e+00</td>
      <td>0.000000</td>
      <td>NaN</td>
    </tr>
    <tr>
      <th>LRRK2</th>
      <td>5.158378e+08</td>
      <td>0.010307</td>
      <td>2.204069e+08</td>
      <td>0.004188</td>
      <td>0.427279</td>
    </tr>
    <tr>
      <th>MAPKAPK2</th>
      <td>1.250987e+09</td>
      <td>0.024996</td>
      <td>7.768801e+08</td>
      <td>0.014762</td>
      <td>0.621014</td>
    </tr>
    <tr>
      <th>Mer</th>
      <td>5.158378e+08</td>
      <td>0.010307</td>
      <td>2.204069e+08</td>
      <td>0.004188</td>
      <td>0.427279</td>
    </tr>
    <tr>
      <th>PDK1</th>
      <td>5.158378e+08</td>
      <td>0.010307</td>
      <td>2.204069e+08</td>
      <td>0.004188</td>
      <td>0.427279</td>
    </tr>
    <tr>
      <th>PIKFYVE</th>
      <td>5.158378e+08</td>
      <td>0.010307</td>
      <td>2.204069e+08</td>
      <td>0.004188</td>
      <td>0.427279</td>
    </tr>
    <tr>
      <th>PKACA</th>
      <td>7.475659e+08</td>
      <td>0.014937</td>
      <td>1.305335e+09</td>
      <td>0.024804</td>
      <td>1.746113</td>
    </tr>
    <tr>
      <th>PKCA</th>
      <td>5.291627e+08</td>
      <td>0.010573</td>
      <td>2.399054e+08</td>
      <td>0.004559</td>
      <td>0.453368</td>
    </tr>
    <tr>
      <th>PKCB</th>
      <td>5.158378e+08</td>
      <td>0.010307</td>
      <td>2.204069e+08</td>
      <td>0.004188</td>
      <td>0.427279</td>
    </tr>
    <tr>
      <th>PKCD</th>
      <td>1.332489e+07</td>
      <td>0.000266</td>
      <td>1.949857e+07</td>
      <td>0.000371</td>
      <td>1.463319</td>
    </tr>
    <tr>
      <th>PKCZ</th>
      <td>1.332489e+07</td>
      <td>0.000266</td>
      <td>1.949857e+07</td>
      <td>0.000371</td>
      <td>1.463319</td>
    </tr>
    <tr>
      <th>PKM</th>
      <td>6.457577e+07</td>
      <td>0.001290</td>
      <td>4.417949e+07</td>
      <td>0.000840</td>
      <td>0.684150</td>
    </tr>
    <tr>
      <th>PLK1</th>
      <td>5.072403e+08</td>
      <td>0.010135</td>
      <td>9.583451e+08</td>
      <td>0.018211</td>
      <td>1.889331</td>
    </tr>
    <tr>
      <th>PRKD1</th>
      <td>5.158378e+08</td>
      <td>0.010307</td>
      <td>2.204069e+08</td>
      <td>0.004188</td>
      <td>0.427279</td>
    </tr>
    <tr>
      <th>TBK1</th>
      <td>5.158378e+08</td>
      <td>0.010307</td>
      <td>2.204069e+08</td>
      <td>0.004188</td>
      <td>0.427279</td>
    </tr>
    <tr>
      <th>mTOR</th>
      <td>1.461482e+09</td>
      <td>0.029202</td>
      <td>8.474366e+08</td>
      <td>0.016103</td>
      <td>0.579847</td>
    </tr>
  </tbody>
</table>
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<div class=" highlight hl-ipython3"><pre><span></span><span class="n">dkinase</span><span class="o">.</span><span class="n">sort_values</span><span class="p">(</span><span class="n">by</span><span class="o">=</span><span class="s1">&#39;mean_FC_kinase&#39;</span><span class="p">,</span> <span class="n">ascending</span><span class="o">=</span><span class="kc">False</span><span class="p">)</span>
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    .dataframe tbody tr th:only-of-type {
        vertical-align: middle;
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<table border="1" class="dataframe">
  <thead>
    <tr style="text-align: right;">
      <th></th>
      <th>Control_mean</th>
      <th>relative_control_activity</th>
      <th>Inhibitor_mean</th>
      <th>relative_inhibitor_activity</th>
      <th>mean_FC_kinase</th>
    </tr>
    <tr>
      <th>Kinase</th>
      <th></th>
      <th></th>
      <th></th>
      <th></th>
      <th></th>
    </tr>
  </thead>
  <tbody>
    <tr>
      <th>AMPKA1</th>
      <td>9.367416e+08</td>
      <td>0.018717</td>
      <td>1.819075e+09</td>
      <td>0.034566</td>
      <td>1.941918</td>
    </tr>
    <tr>
      <th>AMPKA2</th>
      <td>9.367416e+08</td>
      <td>0.018717</td>
      <td>1.819075e+09</td>
      <td>0.034566</td>
      <td>1.941918</td>
    </tr>
    <tr>
      <th>PLK1</th>
      <td>5.072403e+08</td>
      <td>0.010135</td>
      <td>9.583451e+08</td>
      <td>0.018211</td>
      <td>1.889331</td>
    </tr>
    <tr>
      <th>PKACA</th>
      <td>7.475659e+08</td>
      <td>0.014937</td>
      <td>1.305335e+09</td>
      <td>0.024804</td>
      <td>1.746113</td>
    </tr>
    <tr>
      <th>PKCZ</th>
      <td>1.332489e+07</td>
      <td>0.000266</td>
      <td>1.949857e+07</td>
      <td>0.000371</td>
      <td>1.463319</td>
    </tr>
    <tr>
      <th>PKCD</th>
      <td>1.332489e+07</td>
      <td>0.000266</td>
      <td>1.949857e+07</td>
      <td>0.000371</td>
      <td>1.463319</td>
    </tr>
    <tr>
      <th>CDK2</th>
      <td>6.437672e+08</td>
      <td>0.012863</td>
      <td>8.972966e+08</td>
      <td>0.017051</td>
      <td>1.393822</td>
    </tr>
    <tr>
      <th>Abl</th>
      <td>3.553320e+08</td>
      <td>0.007100</td>
      <td>4.794626e+08</td>
      <td>0.009111</td>
      <td>1.349337</td>
    </tr>
    <tr>
      <th>CK2A1</th>
      <td>1.199302e+10</td>
      <td>0.239635</td>
      <td>1.490416e+10</td>
      <td>0.283211</td>
      <td>1.242736</td>
    </tr>
    <tr>
      <th>ERK1</th>
      <td>6.954255e+09</td>
      <td>0.138955</td>
      <td>8.002003e+09</td>
      <td>0.152055</td>
      <td>1.150663</td>
    </tr>
    <tr>
      <th>ERK2</th>
      <td>6.954255e+09</td>
      <td>0.138955</td>
      <td>8.002003e+09</td>
      <td>0.152055</td>
      <td>1.150663</td>
    </tr>
    <tr>
      <th>CDK1</th>
      <td>3.225782e+09</td>
      <td>0.064455</td>
      <td>3.524043e+09</td>
      <td>0.066964</td>
      <td>1.092462</td>
    </tr>
    <tr>
      <th>Chk1</th>
      <td>4.836535e+09</td>
      <td>0.096640</td>
      <td>5.190886e+09</td>
      <td>0.098638</td>
      <td>1.073265</td>
    </tr>
    <tr>
      <th>CDK5</th>
      <td>4.655196e+08</td>
      <td>0.009302</td>
      <td>4.234087e+08</td>
      <td>0.008046</td>
      <td>0.909540</td>
    </tr>
    <tr>
      <th>Akt3</th>
      <td>7.351497e+08</td>
      <td>0.014689</td>
      <td>5.564733e+08</td>
      <td>0.010574</td>
      <td>0.756952</td>
    </tr>
    <tr>
      <th>PKM</th>
      <td>6.457577e+07</td>
      <td>0.001290</td>
      <td>4.417949e+07</td>
      <td>0.000840</td>
      <td>0.684150</td>
    </tr>
    <tr>
      <th>MAPKAPK2</th>
      <td>1.250987e+09</td>
      <td>0.024996</td>
      <td>7.768801e+08</td>
      <td>0.014762</td>
      <td>0.621014</td>
    </tr>
    <tr>
      <th>mTOR</th>
      <td>1.461482e+09</td>
      <td>0.029202</td>
      <td>8.474366e+08</td>
      <td>0.016103</td>
      <td>0.579847</td>
    </tr>
    <tr>
      <th>PKCA</th>
      <td>5.291627e+08</td>
      <td>0.010573</td>
      <td>2.399054e+08</td>
      <td>0.004559</td>
      <td>0.453368</td>
    </tr>
    <tr>
      <th>Mer</th>
      <td>5.158378e+08</td>
      <td>0.010307</td>
      <td>2.204069e+08</td>
      <td>0.004188</td>
      <td>0.427279</td>
    </tr>
    <tr>
      <th>PDK1</th>
      <td>5.158378e+08</td>
      <td>0.010307</td>
      <td>2.204069e+08</td>
      <td>0.004188</td>
      <td>0.427279</td>
    </tr>
    <tr>
      <th>PIKFYVE</th>
      <td>5.158378e+08</td>
      <td>0.010307</td>
      <td>2.204069e+08</td>
      <td>0.004188</td>
      <td>0.427279</td>
    </tr>
    <tr>
      <th>LRRK2</th>
      <td>5.158378e+08</td>
      <td>0.010307</td>
      <td>2.204069e+08</td>
      <td>0.004188</td>
      <td>0.427279</td>
    </tr>
    <tr>
      <th>PKCB</th>
      <td>5.158378e+08</td>
      <td>0.010307</td>
      <td>2.204069e+08</td>
      <td>0.004188</td>
      <td>0.427279</td>
    </tr>
    <tr>
      <th>IKKE</th>
      <td>5.158378e+08</td>
      <td>0.010307</td>
      <td>2.204069e+08</td>
      <td>0.004188</td>
      <td>0.427279</td>
    </tr>
    <tr>
      <th>DNAPK</th>
      <td>5.158378e+08</td>
      <td>0.010307</td>
      <td>2.204069e+08</td>
      <td>0.004188</td>
      <td>0.427279</td>
    </tr>
    <tr>
      <th>AXL</th>
      <td>5.158378e+08</td>
      <td>0.010307</td>
      <td>2.204069e+08</td>
      <td>0.004188</td>
      <td>0.427279</td>
    </tr>
    <tr>
      <th>PRKD1</th>
      <td>5.158378e+08</td>
      <td>0.010307</td>
      <td>2.204069e+08</td>
      <td>0.004188</td>
      <td>0.427279</td>
    </tr>
    <tr>
      <th>TBK1</th>
      <td>5.158378e+08</td>
      <td>0.010307</td>
      <td>2.204069e+08</td>
      <td>0.004188</td>
      <td>0.427279</td>
    </tr>
    <tr>
      <th>ILK</th>
      <td>5.158378e+08</td>
      <td>0.010307</td>
      <td>2.204069e+08</td>
      <td>0.004188</td>
      <td>0.427279</td>
    </tr>
    <tr>
      <th>GSK3B</th>
      <td>1.747978e+09</td>
      <td>0.034927</td>
      <td>3.721304e+08</td>
      <td>0.007071</td>
      <td>0.212892</td>
    </tr>
    <tr>
      <th>GSK3A</th>
      <td>0.000000e+00</td>
      <td>0.000000</td>
      <td>0.000000e+00</td>
      <td>0.000000</td>
      <td>NaN</td>
    </tr>
    <tr>
      <th>JNK1</th>
      <td>0.000000e+00</td>
      <td>0.000000</td>
      <td>0.000000e+00</td>
      <td>0.000000</td>
      <td>NaN</td>
    </tr>
  </tbody>
</table>
</div>
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<div class="prompt input_prompt">In&nbsp;[23]:</div>
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<div class=" highlight hl-ipython3"><pre><span></span><span class="c1">#dkinase.to_html(&#39;output.html&#39;)</span>
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