Skip to content

Commit

Permalink
Updated web content
Browse files Browse the repository at this point in the history
  • Loading branch information
robjgiff committed Sep 4, 2024
1 parent 57dfc5e commit af0b978
Show file tree
Hide file tree
Showing 3 changed files with 19 additions and 11 deletions.
Binary file added website/assets/images/cat-dog-hbv.png
Loading
Sorry, something went wrong. Reload?
Sorry, we cannot display this file.
Sorry, this file is invalid so it cannot be displayed.
20 changes: 16 additions & 4 deletions website/html/news.html
Original file line number Diff line number Diff line change
Expand Up @@ -31,7 +31,7 @@ <h2 class="project-tagline">Resources for comparative genomic analysis of hepadn


<h3>
<a id="EqHBV" class="anchor" href="#EqHBV" aria-hidden="true"><span aria-hidden="true" class="octicon octicon-link"></span></a><strong>2024-09-04: New Discoveries: Domestic Cat and Dog Hepadnaviruses Added to Hepadnavirus-GLUE</strong>
<a id="CarnivoreHBVs" class="anchor" href="#EqHBV" aria-hidden="true"><span aria-hidden="true" class="octicon octicon-link"></span></a><strong>2024-09-04: New Discoveries: Domestic Cat and Dog Hepadnaviruses Added to Hepadnavirus-GLUE</strong>
</h3>
<hr>

Expand All @@ -40,9 +40,19 @@ <h3>
Complete genome reference sequences of two novel hepadnaviruses, identified in
<b><a target="_blank" href="https://doi.org/10.3390/v10050269">domestic cats</a></b> and
<b><a target="_blank" href="https://doi.org/10.1038/s41598-022-06842-z">domestic dogs</a></b>,
have been added to the Hepadnavirus-GLUE project.
have been added to <b>Hepadnavirus-GLUE</b>.
</p>



<img src="../assets/images/cat-dog-hbv.png" alt="Carnivore hepatitis B virus related images"/>

<blockquote>
<p>
The identification of hepadnaviruses in domestic carnivores underscores the growing recognition of broader diversity within the <i>Hepadnaviridae</i> family.
</p>
</blockquote>

<p>
In Australia, researchers identified a novel hepadnavirus in an immunocompromised domestic cat. This virus, tentatively named domestic cat hepadnavirus, was discovered through high-throughput transcriptome sequencing of tissues from cats infected with feline immunodeficiency virus (FIV). The virus was detected in 10% of FIV-infected cats and 3.2% of FIV-uninfected cats, indicating its potential role as a co-infecting agent in immunosuppressed animals. Phylogenetic analysis places the domestic cat hepadnavirus as a highly divergent member of the mammalian orthohepadnaviruses, marking the first time a hepadnavirus has been found in a carnivore or companion animal.
</p>
Expand Down Expand Up @@ -75,7 +85,9 @@ <h3>
</blockquote>

<p>
The recent discovery of Equine Hepatitis B Virus (EqHBV) in zebras and donkeys presents exciting new opportunities for comparative research within the Hepadnaviridae family. To facilitate these studies, we have integrated EqHBV into the Hepadnaviridae-GLUE resource.
The recent discovery of Equine Hepatitis B Virus (EqHBV) in zebras and donkeys
presents exciting new opportunities for comparative research within the Hepadnaviridae family.
To facilitate these studies, we have integrated EqHBV into the <b>Hepadnavirus-GLUE</b> resource.
</p>


Expand All @@ -86,7 +98,7 @@ <h3>


<p>
Hepadnavirus-GLUE is the second broadly-scoped
<b>Hepadnavirus-GLUE</b> is the second, broadly-scoped
<a target="_blank" href="http://glue-tools.cvr.gla.ac.uk/"><b>GLUE</b></a>
project to be published by the
<a target="_blank" href="https://github.com/giffordlabcvr"><b>Gifford lab</b></a>.
Expand Down
10 changes: 3 additions & 7 deletions website/html/viruses.html
Original file line number Diff line number Diff line change
Expand Up @@ -64,10 +64,6 @@ <h3>
(<a target="_blank" href="https://github.com/giffordlabcvr/HBV-GLUE-WEB"><b>HBV-GLUE-WEB</b></a>),
that allows users to browse and interrogate the underlying GLUE database
via 'point-and-click' methods.
</p>


<p>
The <b>MRC-University of Glasgow Centre for Virus Research</b> hosts an instance of the
<a target="_blank" href="http://hbv-glue.cvr.gla.ac.uk/"><b>GUI version of HBV-GLUE</b></a>.

Expand All @@ -76,7 +72,7 @@ <h3>

<br>
<h3>
<a id="genomeFeatures" class="anchor" href="#sequenceData" aria-hidden="true"><span aria-hidden="true" class="octicon octicon-link"></span></a><strong>Hepadnavirus genome features</strong>
<a id="genomeFeatures" class="anchor" href="#sequenceData" aria-hidden="true"><span aria-hidden="true" class="octicon octicon-link"></span></a><strong>Genome features</strong>
</h3>
<hr>

Expand All @@ -102,7 +98,7 @@ <h3>

<br>
<h3>
<a id="sequenceData" class="anchor" href="#sequenceData" aria-hidden="true"><span aria-hidden="true" class="octicon octicon-link"></span></a><strong>Hepadnavirus sequences and sequence-associated data</strong>
<a id="sequenceData" class="anchor" href="#sequenceData" aria-hidden="true"><span aria-hidden="true" class="octicon octicon-link"></span></a><strong>Sequences and sequence-associated data</strong>
</h3>
<hr>

Expand Down Expand Up @@ -131,7 +127,7 @@ <h3>

<br>
<h3>
<a id="virusReferenceSequences" class="anchor" href="#sequenceData" aria-hidden="true"><span aria-hidden="true" class="octicon octicon-link"></span></a><strong>Hepadnavirus reference sequences</strong>
<a id="virusReferenceSequences" class="anchor" href="#sequenceData" aria-hidden="true"><span aria-hidden="true" class="octicon octicon-link"></span></a><strong>Reference sequences</strong>
</h3>
<hr>

Expand Down

0 comments on commit af0b978

Please sign in to comment.