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Update README.md
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dawnmy authored Jan 5, 2022
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In this benchmarking study: variants callers `BCFtools` (v1.9), `VarScan` (v2.4.3), `Freebayes` (v1.2.0), `LoFreq` (v2.1.3.1), `CLC Genomics Workbench` (v11.0.1) were evaluated. For the assembly benchmarking, `ABySS` (v2.1.4), `megahit` (v1.1.3) , `IDBA` (v1.1.3), `SPAdes` (v3.12.0), `Ray` (v2.3.1), `Tadpole` (v37.99) were assessed. The haplotype reconstruction program `Savage` (v0.4.0) was also evaluated.


### Prerequirements

To reproduce the output, you need to use `Bioconda`.
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runOnReads: false # Run the whole analyses on reads. Controlled by the `--slow` option
```
### Run the benchmarking
**All evaluation can be launched with `run_benchmark.py`**
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-r "<comma-separated list of reference genomes>" \
-o <output directory>
```

### Citation
Deng ZL, Dhingra A, Fritz A, Götting J, Münch PC, Steinbrück L, Schulz T, Ganzenmueller T, McHardy AC. Evaluating assembly and variant calling software for strain-resolved analysis of large DNA-viruses. Briefings in Bioinformatics. 2020:7. https://doi.org/10.1093/bib/bbaa123

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