Skip to content

Commit

Permalink
Merge pull request #562 from monarch-initiative/issue-543-pharm
Browse files Browse the repository at this point in the history
actual release
  • Loading branch information
Leigh Carmody authored May 17, 2023
2 parents d4677a9 + b57f241 commit bc6132d
Show file tree
Hide file tree
Showing 18 changed files with 15,315 additions and 10,702 deletions.
185 changes: 181 additions & 4 deletions maxo-base.json
Original file line number Diff line number Diff line change
Expand Up @@ -25,9 +25,9 @@
"val" : "https://creativecommons.org/licenses/by/4.0/"
}, {
"pred" : "http://www.w3.org/2002/07/owl#versionInfo",
"val" : "2023-05-02"
"val" : "2023-05-17"
} ],
"version" : "http://purl.obolibrary.org/obo/maxo/releases/2023-05-02/maxo-base.json"
"version" : "http://purl.obolibrary.org/obo/maxo/releases/2023-05-17/maxo-base.json"
},
"nodes" : [ {
"id" : "http://purl.obolibrary.org/obo/MAXO_0000001",
Expand Down Expand Up @@ -7423,7 +7423,7 @@
}
}, {
"id" : "http://purl.obolibrary.org/obo/MAXO_0000259",
"lbl" : "therapeutic insulin treatment",
"lbl" : "insulin treatment",
"type" : "CLASS",
"meta" : {
"definition" : {
Expand All @@ -7439,6 +7439,9 @@
}, {
"pred" : "hasExactSynonym",
"val" : "therapeutic insulin preparations treatment"
}, {
"pred" : "hasExactSynonym",
"val" : "therapeutic insulin therapy"
} ],
"xrefs" : [ {
"val" : "NCIT:C581"
Expand Down Expand Up @@ -33211,6 +33214,9 @@
"val" : "Use of a drug or agent that modulates parasympatholytic signaling."
},
"synonyms" : [ {
"pred" : "hasExactSynonym",
"val" : "dopaminergic modifying agent therapy"
}, {
"pred" : "hasExactSynonym",
"val" : "treatment with parasympatholytic"
} ],
Expand All @@ -33224,7 +33230,7 @@
}
}, {
"id" : "http://purl.obolibrary.org/obo/MAXO_0001331",
"lbl" : "dopaminergic modifying agent therapy",
"lbl" : "dopaminergic agent therapy",
"type" : "CLASS",
"meta" : {
"definition" : {
Expand Down Expand Up @@ -35906,6 +35912,141 @@
"val" : "http://orcid.org/0000-0001-7941-2961"
} ]
}
}, {
"id" : "http://purl.obolibrary.org/obo/MAXO_0001469",
"lbl" : "farnesyltransferase inhibitor agent therapy",
"type" : "CLASS",
"meta" : {
"definition" : {
"val" : "Use of a drug or agent that inhibits farnesyltransferase."
},
"synonyms" : [ {
"pred" : "hasExactSynonym",
"val" : "farnesyltransferase inhibitor treatment"
}, {
"pred" : "hasExactSynonym",
"val" : "treatment with http://purl.obolibrary.org/obo/CHEBI_64133"
} ],
"basicPropertyValues" : [ {
"pred" : "http://purl.org/dc/elements/1.1/date",
"val" : "2023-05-15T11:00:00Z"
}, {
"pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
"val" : "http://orcid.org/0000-0003-4830-7530"
} ]
}
}, {
"id" : "http://purl.obolibrary.org/obo/MAXO_0001470",
"lbl" : "MMP inhibitor agent therapy",
"type" : "CLASS",
"meta" : {
"definition" : {
"val" : "Use of a drug or agent that inhibits matrix metalloprotease inhibitor."
},
"synonyms" : [ {
"pred" : "hasExactSynonym",
"val" : "treatment with http://purl.obolibrary.org/obo/CHEBI_50664"
} ],
"basicPropertyValues" : [ {
"pred" : "http://purl.org/dc/elements/1.1/date",
"val" : "2023-05-15T11:00:00Z"
}, {
"pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
"val" : "http://orcid.org/0000-0001-7941-2961"
} ]
}
}, {
"id" : "http://purl.obolibrary.org/obo/MAXO_0001471",
"lbl" : "tazarotene agent therapy",
"type" : "CLASS",
"meta" : {
"definition" : {
"val" : "Treatment with a topical cream that is used to treat psoriasis."
},
"basicPropertyValues" : [ {
"pred" : "http://purl.org/dc/elements/1.1/date",
"val" : "2023-05-15T11:00:00Z"
}, {
"pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
"val" : "http://orcid.org/0000-0001-7941-2961"
} ]
}
}, {
"id" : "http://purl.obolibrary.org/obo/MAXO_0001473",
"lbl" : "benzothiadiazine derivative therapy",
"type" : "CLASS",
"meta" : {
"definition" : {
"val" : "Treatment with a diuretic to treat hypertension or edema."
},
"basicPropertyValues" : [ {
"pred" : "http://purl.org/dc/elements/1.1/date",
"val" : "2023-05-15T11:00:00Z"
}, {
"pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
"val" : "http://orcid.org/0000-0001-7941-2961"
} ]
}
}, {
"id" : "http://purl.obolibrary.org/obo/MAXO_0001474",
"lbl" : "thyroid hormone therapy",
"type" : "CLASS",
"meta" : {
"definition" : {
"val" : "Treatment with thyroid hormone or drugs replicating thyroid hormone to maintain a normally functioning thyroid."
},
"synonyms" : [ {
"pred" : "hasExactSynonym",
"val" : "treatment with http://purl.obolibrary.org/obo/CHEBI_60311"
} ],
"basicPropertyValues" : [ {
"pred" : "http://purl.org/dc/elements/1.1/date",
"val" : "2023-05-15T11:00:00Z"
}, {
"pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
"val" : "http://orcid.org/0000-0001-7941-2961"
} ]
}
}, {
"id" : "http://purl.obolibrary.org/obo/MAXO_0001475",
"lbl" : "sodium-glucose cotransporter-2 inhibitor therapy",
"type" : "CLASS",
"meta" : {
"definition" : {
"val" : "Treatment with a class of medicines inhibit sodium-glucose cotransporter-2. Drugs are used with diet and exercise to lower blood sugar in adults with type 2 diabetes."
},
"synonyms" : [ {
"pred" : "hasExactSynonym",
"val" : "treatment with http://purl.obolibrary.org/obo/CHEBI_73273"
} ],
"basicPropertyValues" : [ {
"pred" : "http://purl.org/dc/elements/1.1/date",
"val" : "2023-05-15T11:00:00Z"
}, {
"pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
"val" : "http://orcid.org/0000-0001-7941-2961"
} ]
}
}, {
"id" : "http://purl.obolibrary.org/obo/MAXO_0001476",
"lbl" : "somatostatin recepter agonist therapy",
"type" : "CLASS",
"meta" : {
"definition" : {
"val" : "Treatment with an activator to the somatostatin receptor."
},
"synonyms" : [ {
"pred" : "hasExactSynonym",
"val" : "treatment with http://purl.obolibrary.org/obo/CHEBI_177023"
} ],
"basicPropertyValues" : [ {
"pred" : "http://purl.org/dc/elements/1.1/date",
"val" : "2023-05-15T11:00:00Z"
}, {
"pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
"val" : "http://orcid.org/0000-0001-7941-2961"
} ]
}
}, {
"id" : "http://purl.obolibrary.org/obo/MAXO_0002000",
"lbl" : "cannabis consumption avoidance",
Expand Down Expand Up @@ -50989,6 +51130,13 @@
}, {
"definedClassId" : "http://purl.obolibrary.org/obo/MAXO_0000256",
"genusIds" : [ "http://purl.obolibrary.org/obo/MAXO_0000058" ]
}, {
"definedClassId" : "http://purl.obolibrary.org/obo/MAXO_0000259",
"genusIds" : [ "http://purl.obolibrary.org/obo/MAXO_0000058" ],
"restrictions" : [ {
"propertyId" : "http://purl.obolibrary.org/obo/MAXO_0000864",
"fillerId" : "http://purl.obolibrary.org/obo/CHEBI_145810"
} ]
}, {
"definedClassId" : "http://purl.obolibrary.org/obo/MAXO_0000260",
"genusIds" : [ "http://purl.obolibrary.org/obo/MAXO_0000058" ]
Expand Down Expand Up @@ -53148,6 +53296,35 @@
}, {
"definedClassId" : "http://purl.obolibrary.org/obo/MAXO_0001468",
"genusIds" : [ "http://purl.obolibrary.org/obo/MAXO_0000447" ]
}, {
"definedClassId" : "http://purl.obolibrary.org/obo/MAXO_0001469",
"genusIds" : [ "http://purl.obolibrary.org/obo/MAXO_0000058" ]
}, {
"definedClassId" : "http://purl.obolibrary.org/obo/MAXO_0001470",
"genusIds" : [ "http://purl.obolibrary.org/obo/MAXO_0000058" ]
}, {
"definedClassId" : "http://purl.obolibrary.org/obo/MAXO_0001471",
"genusIds" : [ "http://purl.obolibrary.org/obo/MAXO_0000058" ],
"restrictions" : [ {
"propertyId" : "http://purl.obolibrary.org/obo/MAXO_0000864",
"fillerId" : "http://purl.obolibrary.org/obo/CHEBI_32184"
} ]
}, {
"definedClassId" : "http://purl.obolibrary.org/obo/MAXO_0001473",
"genusIds" : [ "http://purl.obolibrary.org/obo/MAXO_0000058" ],
"restrictions" : [ {
"propertyId" : "http://purl.obolibrary.org/obo/MAXO_0000864",
"fillerId" : "http://purl.obolibrary.org/obo/CHEBI_50265"
} ]
}, {
"definedClassId" : "http://purl.obolibrary.org/obo/MAXO_0001474",
"genusIds" : [ "http://purl.obolibrary.org/obo/MAXO_0000058" ]
}, {
"definedClassId" : "http://purl.obolibrary.org/obo/MAXO_0001475",
"genusIds" : [ "http://purl.obolibrary.org/obo/MAXO_0000058" ]
}, {
"definedClassId" : "http://purl.obolibrary.org/obo/MAXO_0001476",
"genusIds" : [ "http://purl.obolibrary.org/obo/MAXO_0000058" ]
}, {
"definedClassId" : "http://purl.obolibrary.org/obo/MAXO_0009078",
"genusIds" : [ "http://purl.obolibrary.org/obo/MAXO_0009076" ]
Expand Down
71 changes: 67 additions & 4 deletions maxo-base.obo
Original file line number Diff line number Diff line change
@@ -1,5 +1,5 @@
format-version: 1.2
data-version: maxo/releases/2023-05-02/maxo-base.owl
data-version: maxo/releases/2023-05-17/maxo-base.owl
ontology: maxo/maxo-base
property_value: http://purl.org/dc/elements/1.1/creator "Leigh Carmody" xsd:string
property_value: http://purl.org/dc/elements/1.1/creator "Peter Robinson" xsd:string
Expand All @@ -8,7 +8,7 @@ property_value: http://purl.org/dc/elements/1.1/title "Medical Action Ontology"
property_value: http://purl.org/dc/elements/1.1/type IAO:8000001
property_value: http://purl.org/dc/terms/license https://creativecommons.org/licenses/by/4.0/
property_value: IAO:0000700 MAXO:0000001
property_value: owl:versionInfo "2023-05-02" xsd:string
property_value: owl:versionInfo "2023-05-17" xsd:string

[Term]
id: MAXO:0000001
Expand Down Expand Up @@ -3072,13 +3072,16 @@ created_by: http://orcid.org/0000-0001-7941-2961

[Term]
id: MAXO:0000259
name: therapeutic insulin treatment
name: insulin treatment
def: "A synthetic or animal-derived form of insulin used in the treatment of diabetes mellitus. Therapeutic insulin is formulated to be short-, intermediate- and long-acting in order to individualize an insulin regimen according to individual differences in glucose and insulin metabolism. Therapeutic insulin may be derived from porcine, bovine or recombinant sources. Endogenous human insulin, a pancreatic hormone composed of two polypeptide chains, is important for the normal metabolism of carbohydrates, proteins and fats and has anabolic effects on many types of tissues." [NCIT:C581]
synonym: "insulin drug treatment" EXACT []
synonym: "insulin therapy" EXACT []
synonym: "therapeutic insulin preparations treatment" EXACT []
synonym: "therapeutic insulin therapy" EXACT []
xref: NCIT:C581
is_a: MAXO:0000572 ! hypoglycemic drug therapy
intersection_of: MAXO:0000058 ! pharmacotherapy
intersection_of: MAXO:0000864 CHEBI:145810 ! therapeutic uses
property_value: http://purl.org/dc/elements/1.1/date "2019-01-22T20:33:51Z" xsd:dateTime
created_by: http://orcid.org/0000-0001-7941-2961

Expand Down Expand Up @@ -13901,13 +13904,14 @@ created_by: http://orcid.org/0000-0001-7941-2961
id: MAXO:0001330
name: parasympatholytic therapy
def: "Use of a drug or agent that modulates parasympatholytic signaling." []
synonym: "dopaminergic modifying agent therapy" EXACT []
synonym: "treatment with parasympatholytic" EXACT []
property_value: http://purl.org/dc/elements/1.1/date "2023-02-23T11:00:00Z" xsd:string
created_by: http://orcid.org/0000-0001-7941-2961

[Term]
id: MAXO:0001331
name: dopaminergic modifying agent therapy
name: dopaminergic agent therapy
def: "Use of a drug or agent that modulates dopamine signaling." []
synonym: "treatment with dopaminergic agent" EXACT []
property_value: http://purl.org/dc/elements/1.1/date "2023-02-23T11:00:00Z" xsd:string
Expand Down Expand Up @@ -14984,6 +14988,65 @@ is_a: MAXO:0000993 ! removal of skin
property_value: http://purl.org/dc/elements/1.1/date "2023-03-31T20:39:14Z" xsd:string
created_by: http://orcid.org/0000-0001-7941-2961

[Term]
id: MAXO:0001469
name: farnesyltransferase inhibitor agent therapy
def: "Use of a drug or agent that inhibits farnesyltransferase." []
synonym: "farnesyltransferase inhibitor treatment" EXACT []
synonym: "treatment with http://purl.obolibrary.org/obo/CHEBI_64133" EXACT []
property_value: http://purl.org/dc/elements/1.1/date "2023-05-15T11:00:00Z" xsd:string
created_by: http://orcid.org/0000-0003-4830-7530

[Term]
id: MAXO:0001470
name: MMP inhibitor agent therapy
def: "Use of a drug or agent that inhibits matrix metalloprotease inhibitor." []
synonym: "treatment with http://purl.obolibrary.org/obo/CHEBI_50664" EXACT []
property_value: http://purl.org/dc/elements/1.1/date "2023-05-15T11:00:00Z" xsd:string
created_by: http://orcid.org/0000-0001-7941-2961

[Term]
id: MAXO:0001471
name: tazarotene agent therapy
def: "Treatment with a topical cream that is used to treat psoriasis." []
intersection_of: MAXO:0000058 ! pharmacotherapy
intersection_of: MAXO:0000864 CHEBI:32184 ! therapeutic uses
property_value: http://purl.org/dc/elements/1.1/date "2023-05-15T11:00:00Z" xsd:string
created_by: http://orcid.org/0000-0001-7941-2961

[Term]
id: MAXO:0001473
name: benzothiadiazine derivative therapy
def: "Treatment with a diuretic to treat hypertension or edema." []
intersection_of: MAXO:0000058 ! pharmacotherapy
intersection_of: MAXO:0000864 CHEBI:50265 ! therapeutic uses
property_value: http://purl.org/dc/elements/1.1/date "2023-05-15T11:00:00Z" xsd:string
created_by: http://orcid.org/0000-0001-7941-2961

[Term]
id: MAXO:0001474
name: thyroid hormone therapy
def: "Treatment with thyroid hormone or drugs replicating thyroid hormone to maintain a normally functioning thyroid." []
synonym: "treatment with http://purl.obolibrary.org/obo/CHEBI_60311" EXACT []
property_value: http://purl.org/dc/elements/1.1/date "2023-05-15T11:00:00Z" xsd:string
created_by: http://orcid.org/0000-0001-7941-2961

[Term]
id: MAXO:0001475
name: sodium-glucose cotransporter-2 inhibitor therapy
def: "Treatment with a class of medicines inhibit sodium-glucose cotransporter-2. Drugs are used with diet and exercise to lower blood sugar in adults with type 2 diabetes." []
synonym: "treatment with http://purl.obolibrary.org/obo/CHEBI_73273" EXACT []
property_value: http://purl.org/dc/elements/1.1/date "2023-05-15T11:00:00Z" xsd:string
created_by: http://orcid.org/0000-0001-7941-2961

[Term]
id: MAXO:0001476
name: somatostatin recepter agonist therapy
def: "Treatment with an activator to the somatostatin receptor." []
synonym: "treatment with http://purl.obolibrary.org/obo/CHEBI_177023" EXACT []
property_value: http://purl.org/dc/elements/1.1/date "2023-05-15T11:00:00Z" xsd:string
created_by: http://orcid.org/0000-0001-7941-2961

[Term]
id: MAXO:0002000
name: cannabis consumption avoidance
Expand Down
Loading

0 comments on commit bc6132d

Please sign in to comment.