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clean the rest of the chapter
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seohyonkim committed Jan 31, 2025
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10 changes: 10 additions & 0 deletions jupyter-book/glossary.md
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Demultiplexing
The process of determining which sequencing reads belong to which cell using {term}`barcodes`.
directed graph
A directed graph (or digraph) is a graph consisting of a set of nodes (vertices) connected by edges (arcs), where each edge has a direction indicating a one-way relationship between nodes.
DNA
DNA is the acronym of Deoxyribonucleic acid.
It is the organic chemical storing hereditary information and instructions for protein synthesis.
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Drop-seq
A protocol for scRNA-seq that separates cells into nano-liter sized aqueous droplets enabling large-scale profiling.
Edit distance
Edit distance (often referring to Levenshtein distance) measures the minimum number of operations (Substitution, Insertion, Deletion) required to transform one string into another.
FASTQ reads
Sequencing reads that are saved in the FASTQ format.
FASTQ files are then used to map against the reference genome of interest to obtain gene counts for cells.
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Gene expression matrix
A cell (barcode) by gene (scverse ecosystem) or gene by cell (barcode) matrix storing counts in the cell values.
Hamming distance
A measure of the number of positions at which two strings of equal length differ.
It is commonly used in error detection and correction, including barcode correction in sequencing data.
Imputation
The replacement of missing values with usually artificial values.
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