python deep-learning publication blob-detection diffraction-limited-spots spot-detection

deep-learning segmentation cell-segmentation cell-biology u-net 3d-volume microscopy-images diffraction-limited-spots spot-detection

region-of-interest band-pass-filter statistical-significance-test metrics-evaluation diffraction-limited-spots scale-space-feature-detection total-internal-reflection-fluorescence-micscopy epifluorescence-microscopy fluorescent-speckle-microscopy low-signal-to-noise-ratio subresolution-cluster-of-fluorophores speckle-modulation-analysis imaging-technique-evaluation imaging-quality-metrics gaussian-spatial-frequencies-filtering 2d-convolution-operator image-noise-reduction bessel-function-to-gaussian-fitting vinculin latrunculin

inflection-point bessel-function intensity-curvature jacobian-matrix diffraction-limited-spots difference-of-gaussian scale-space-feature-detection resolution-limit low-snr fluorescent-speckle-microscopy point-spread-function-fitting objective-function-optimization generalized-sparrow-limit detection-success-rate change-of-sign-2nd-derivative airy-disk-modeling subresolution-cluster-fluorophores feature-fusion-due-to-noise computationally-inexpensive-detection