BIRC3
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timeline
title Publication timing
2011-11-03 : Rossi : MZL
2013-11-05 : Be : MCL
2018-10-01 : Arthur : DLBCL
2021-07-15 : Duns : PMBL
| Entity | Tier | Description |
|---|---|---|
 |
2 | relevance in PMBL/cHL/GZL not firmly established[@dunsCharacterizationDLBCLPMBL2021b] |
 |
1 | high-confidence MZL gene[@rossiAlterationBIRC3Multiple2011a] |
 |
2-a | aSHM target; Although recurrent, the relevance of mutations in DLBCL is tenuous [@arthurGenomewideDiscoverySomatic2018] |
 |
1-a | aSHM target and high-confidence MCL gene [@beaLandscapeSomaticMutations2013] |
| Entity | source | frequency (%) |
|---|---|---|
| DLBCL | GAMBL genomes | 1.53 |
| DLBCL | Schmitz cohort | 1.91 |
| DLBCL | Reddy cohort | 1.30 |
| DLBCL | Chapuy cohort | 1.71 |
| MCL | GAMBL genomes | 7.11 |
| Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
|---|---|---|---|---|
| BL | Yes | No | 0.000 | 0 |
| DLBCL | Yes | No | 1.404 | 0 |
| FL | Yes | No | 2.427 | 0 |
| chr_name | hg19_start | hg19_end | region | regulatory_comment |
|---|---|---|---|---|
| chr11 | 102188170 | 102190077 | TSS | active_promoter |
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38
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