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rdmorin edited this page Jun 3, 2024 · 5 revisions

title: 'DLBCL genes' bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

DLBCL genes

Origins of DLBCL genessankey

Tier 1 DLBCL genes

128 total

Gene Tier Relevant references
ACTB 1, aSHM [@wienandGenomicAnalysesFlowsorted2019b; @lohrDiscoveryPrioritizationSomatic2012a]
ACTG1 1, aSHM [@spinaGeneticsNodalMarginal2016b; @deschGenotypingCirculatingTumor2020; @hubschmannMutationalMechanismsShaping2021b]
ARID1A 1 [@rossiCodingGenomeSplenic2012c; @wienandGenomicAnalysesFlowsorted2019b; @loveGeneticLandscapeMutations2012; @zhangGeneticHeterogeneityDiffuse2013; @krysiakRecurrentSomaticMutations2017b]
ATM 1 [@braggioGenomicAnalysisMarginal2012; @beaLandscapeSomaticMutations2013; @reddyGeneticFunctionalDrivers2017]
B2M 1 [@pararajalingamCodingNoncodingDrivers2020; @reichelFlowSortingExome2015a; @morinFrequentMutationHistonemodifying2011]
BCL10 1 [@morinFrequentMutationHistonemodifying2011; @russler-germainMutationsAssociatedProgression2023b; @spinaGeneticsNodalMarginal2016b]
BCL2 1, aSHM [@sarkozyMutationalLandscapeGray2021a; @tanakaFrequentIncidenceSomatic1992; @burkhardtClinicalRelevanceMolecular2022b; @morinFrequentMutationHistonemodifying2011]
BCL6 1, aSHM [@morinFrequentMutationHistonemodifying2011; @loveGeneticLandscapeMutations2012]
BCL7A 1, aSHM [@reichelFlowSortingExome2015a; @krysiakRecurrentSomaticMutations2017b; @arthurGenomewideDiscoverySomatic2018; @grandeGenomewideDiscoverySomatic2019]
BIRC6 1 [@reddyGeneticFunctionalDrivers2017; @sarkozyMutationalLandscapeGray2021a]
BRAF 1 [@loveGeneticLandscapeMutations2012; @tiacciBRAFMutationsHairycell2011a]
BTG1 1, aSHM [@morinFrequentMutationHistonemodifying2011; @burkhardtClinicalRelevanceMolecular2022b; @sarkozyMutationalLandscapeGray2021a]
BTG2 1, aSHM [@morinFrequentMutationHistonemodifying2011; @loveGeneticLandscapeMutations2012]
BTK 1 [@krysiakRecurrentSomaticMutations2017b; @albuquerqueEnhancingKnowledgeDiscovery2017a]
CARD11 1 [@wuGeneticHeterogeneityPrimary2016; @paneaWholeGenomeLandscape2019; @lenzOncogenicCARD11Mutations2008; @yanBCRTLRSignaling2012a; @morinFrequentMutationHistonemodifying2011]
CCND3 1 [@jalladesExomeSequencingIdentifies2017; @richterRecurrentMutationID32012a; @deschGenotypingCirculatingTumor2020; @morinFrequentMutationHistonemodifying2011]
CD58 1 [@morinFrequentMutationHistonemodifying2011; @schneiderAlterationsCD58Gene2015a]
CD70 1 [@russler-germainMutationsAssociatedProgression2023b; @morinFrequentMutationHistonemodifying2011]
CD79B 1 [@morinFrequentMutationHistonemodifying2011; @paneaWholeGenomeLandscape2019]
CD83 1, aSHM [@russler-germainMutationsAssociatedProgression2023b; @morinMutationalStructuralAnalysis2013; @dunsCharacterizationDLBCLPMBL2021b; @paneaWholeGenomeLandscape2019]
CDKN2A 1 [@grandeGenomewideDiscoverySomatic2019; @spinaGeneticsNodalMarginal2016b; @morinMutationalStructuralAnalysis2013]
CIITA 1, aSHM [@mottokGenomicAlterationsCIITA2015b; @morinFrequentMutationHistonemodifying2011]
CREBBP 1 [@dunsCharacterizationDLBCLPMBL2021b; @pasqualucciInactivatingMutationsAcetyltransferase2011a; @loveGeneticLandscapeMutations2012; @parryWholeExomeSequencing2013]
CXCR4 1, aSHM [@khodabakhshiRecurrentTargetsAberrant2012; @paneaWholeGenomeLandscape2019; @krysiakRecurrentSomaticMutations2017b]
CXCR5 1 [@schmitzGeneticsPathogenesisDiffuse2018a; @mottokIntegrativeGenomicAnalysis2019b]
DDX3X 1 [@schmitzBurkittLymphomaPathogenesis2012; @mottokIntegrativeGenomicAnalysis2019b; @schmitzGeneticsPathogenesisDiffuse2018a]
DTX1 1, aSHM [@paneaWholeGenomeLandscape2019; @gomezUltraDeepSequencingReveals2023; @schmitzGeneticsPathogenesisDiffuse2018a; @rossiCodingGenomeSplenic2012c]
DUSP2 1, aSHM [@dunsCharacterizationDLBCLPMBL2021b; @morinMutationalStructuralAnalysis2013]
EBF1 1, aSHM [@reichelFlowSortingExome2015a; @bohleRoleEarlyBcell2013; @thomasGeneticSubgroupsInform2023]
EEF1A1 1 [@hubschmannMutationalMechanismsShaping2021b; @reichelFlowSortingExome2015a]
EP300 1 [@rossiCodingGenomeSplenic2012c; @paneaWholeGenomeLandscape2019; @pasqualucciInactivatingMutationsAcetyltransferase2011a]
ETS1 1, aSHM [@paneaWholeGenomeLandscape2019; @morinFrequentMutationHistonemodifying2011]
ETV6 1, aSHM [@arthurGenomewideDiscoverySomatic2018]
EZH2 1 [@morinSomaticMutationsAltering2010a; @mottokIntegrativeGenomicAnalysis2019b; @loveGeneticLandscapeMutations2012]
FAS 1 [@schollMutationsRegionFAS2007; @spinaGeneticsNodalMarginal2016b]
FBXO11 1 [@richterRecurrentMutationID32012a; @hubschmannMutationalMechanismsShaping2021b; @parryWholeExomeSequencing2013]
FBXW7 1 [@zhangGeneticHeterogeneityDiffuse2013]
FOXO1 1 [@schmitzBurkittLymphomaPathogenesis2012; @morinFrequentMutationHistonemodifying2011; @dunsCharacterizationDLBCLPMBL2021b]
GNA13 1 [@loveGeneticLandscapeMutations2012; @morinFrequentMutationHistonemodifying2011; @reichelFlowSortingExome2015a]
GNAI2 1 [@grandeGenomewideDiscoverySomatic2019; @morinMutationalStructuralAnalysis2013]
GRB2 1 [@paneaWholeGenomeLandscape2019; @pasqualucciAnalysisCodingGenome2011]
GRHPR 1, aSHM [@arthurGenomewideDiscoverySomatic2018]
HIST1H1B 1, aSHM [@krysiakRecurrentSomaticMutations2017b; @sarkozyMutationalLandscapeGray2021a; @chapuyMolecularSubtypesDiffuse2018b]
HIST1H1C 1, aSHM [@morinFrequentMutationHistonemodifying2011; @paneaWholeGenomeLandscape2019]
HIST1H1D 1, aSHM [@krysiakRecurrentSomaticMutations2017b; @jalladesExomeSequencingIdentifies2017; @morinMutationalStructuralAnalysis2013]
HIST1H1E 1, aSHM [@morinMutationalStructuralAnalysis2013; @reichelFlowSortingExome2015a; @grandeGenomewideDiscoverySomatic2019; @krysiakRecurrentSomaticMutations2017b]
HIST1H2AC 1, aSHM [@krysiakRecurrentSomaticMutations2017b; @morinMutationalStructuralAnalysis2013]
HIST1H2AM 1, aSHM [@paneaWholeGenomeLandscape2019; @krysiakRecurrentSomaticMutations2017b]
HIST1H2BC 1, aSHM [@krysiakRecurrentSomaticMutations2017b; @mottokIntegrativeGenomicAnalysis2019b; @reddyGeneticFunctionalDrivers2017]
HIST1H2BK 1, aSHM [@paneaWholeGenomeLandscape2019; @rossiCodingGenomeSplenic2012c]
HIST1H3B 1, aSHM [@zhangGeneticHeterogeneityDiffuse2013; @reichelFlowSortingExome2015a]
HIST2H2BE 1, aSHM [@schmitzGeneticsPathogenesisDiffuse2018a]
HLA-A 1 [@deschGenotypingCirculatingTumor2020]
HLA-B 1 [@wienandGenomicAnalysesFlowsorted2019b]
HLA-C 1 [@gomezUltraDeepSequencingReveals2023]
HLA-DMB 1
HNRNPU 1, aSHM [@paneaWholeGenomeLandscape2019; @reddyGeneticFunctionalDrivers2017]
HVCN1 1 [@krysiakRecurrentSomaticMutations2017b]
IKZF3 1 [@morinMutationalStructuralAnalysis2013; @paneaWholeGenomeLandscape2019]
IL4R 1, aSHM [@dunsCharacterizationDLBCLPMBL2021b; @viganoSomaticIL4RMutations2018b]
IRF4 1, aSHM [@mottokIntegrativeGenomicAnalysis2019b; @morinFrequentMutationHistonemodifying2011]
IRF8 1, aSHM [@paneaWholeGenomeLandscape2019; @morinFrequentMutationHistonemodifying2011; @mottokIntegrativeGenomicAnalysis2019b]
ITPKB 1, aSHM [@schmitzGeneticsPathogenesisDiffuse2018a; @reichelFlowSortingExome2015a]
KLF2 1, aSHM [@deschGenotypingCirculatingTumor2020; @jalladesExomeSequencingIdentifies2017; @pasqualucciAnalysisCodingGenome2011]
KLHL14 1 [@zhangGeneticHeterogeneityDiffuse2013]
KLHL6 1, aSHM [@paneaWholeGenomeLandscape2019; @ganapathiGeneticLandscapeDural2016; @morinFrequentMutationHistonemodifying2011]
KMT2C 1 [@zhangGenomicLandscapeMantle2014; @sarkozyMutationalLandscapeGray2021a; @zhouSporadicEndemicBurkitt2019; @zhangGeneticHeterogeneityDiffuse2013]
KMT2D 1 [@deschGenotypingCirculatingTumor2020; @rossiCodingGenomeSplenic2012c; @grandeGenomewideDiscoverySomatic2019; @morinFrequentMutationHistonemodifying2011; @beaLandscapeSomaticMutations2013]
KRAS 1 [@lohrDiscoveryPrioritizationSomatic2012a]
LCOR 1 [@arthurGenomewideDiscoverySomatic2018]
LTB 1, aSHM [@deschGenotypingCirculatingTumor2020; @chapuyMolecularSubtypesDiffuse2018b; @paneaWholeGenomeLandscape2019]
MEF2B 1, aSHM [@beaLandscapeSomaticMutations2013; @morinFrequentMutationHistonemodifying2011]
MEF2C 1, aSHM [@arthurGenomewideDiscoverySomatic2018]
MGA 1 [@jalladesExomeSequencingIdentifies2017; @zhangGeneticHeterogeneityDiffuse2013]
MPEG1 1 [@morinMutationalStructuralAnalysis2013]
MS4A1 1, aSHM [@rushtonGeneticEvolutionaryPatterns2020; @mottokIntegrativeGenomicAnalysis2019b]
MTOR 1 [@zhangGeneticHeterogeneityDiffuse2013; @paneaWholeGenomeLandscape2019]
MYC 1, aSHM [@pasqualucciHypermutationMultipleProtooncogenes2001a; @jalladesExomeSequencingIdentifies2017; @dunsCharacterizationDLBCLPMBL2021b; @johnstonCmycHypermutationBurkitt1992]
MYD88 1 [@yanBCRTLRSignaling2012a; @ngoOncogenicallyActiveMYD882011a]
NFKBIA 1 [@lakeMutationsNFKBIAEncoding2009; @wienandGenomicAnalysesFlowsorted2019b; @russler-germainMutationsAssociatedProgression2023b]
NFKBIE 1 [@morinGeneticLandscapesRelapsed2016; @pararajalingamCodingNoncodingDrivers2020; @mansouriFrequentNFKBIEDeletions2016]
NFKBIZ 1, noncoding [@morinGeneticLandscapesRelapsed2016]
NOL9 1, aSHM [@spinaGeneticsNodalMarginal2016b; @schmitzGeneticsPathogenesisDiffuse2018a]
NOTCH1 1 [@beaLandscapeSomaticMutations2013; @pasqualucciAnalysisCodingGenome2011; @loveGeneticLandscapeMutations2012; @rossiCodingGenomeSplenic2012c]
NOTCH2 1 [@rossiCodingGenomeSplenic2012c; @paneaWholeGenomeLandscape2019; @beaLandscapeSomaticMutations2013; @troenNOTCH2MutationsMarginal2008]
OSBPL10 1, aSHM [@arthurGenomewideDiscoverySomatic2018]
P2RY8 1 [@muppidiLossSignalingGa132014b; @lohrDiscoveryPrioritizationSomatic2012a]
PIM1 1, aSHM [@pasqualucciHypermutationMultipleProtooncogenes2001a; @dunsCharacterizationDLBCLPMBL2021b; @burkhardtClinicalRelevanceMolecular2022b]
PIM2 1, aSHM [@arthurGenomewideDiscoverySomatic2018; @reichelFlowSortingExome2015a]
POU2AF1 1, aSHM [@krysiakRecurrentSomaticMutations2017b]
POU2F2 1 [@krysiakRecurrentSomaticMutations2017b; @zhangGeneticHeterogeneityDiffuse2013]
PRDM1 1 [@pasqualucciInactivationPRDM1BLIMP12006a]
PTEN 1 [@loveGeneticLandscapeMutations2012]
PTPRD 1 [@spinaGeneticsNodalMarginal2016b]
RB1 1 [@zhangGenomicLandscapeMantle2014; @morinMutationalStructuralAnalysis2013]
RFX7 1 [@grandeGenomewideDiscoverySomatic2019]
RHOA 1 [@richterRecurrentMutationID32012a]
RRAGC 1 [@okosunRecurrentMTORC1activatingRRAGC2016a]
S1PR2 1, aSHM [@morinFrequentMutationHistonemodifying2011; @muppidiLossSignalingGa132014b]
SETD1B 1 [@reddyGeneticFunctionalDrivers2017]
SF3B1 1 [@loveGeneticLandscapeMutations2012]
SGK1 1, aSHM [@dunsCharacterizationDLBCLPMBL2021b; @morinFrequentMutationHistonemodifying2011]
SIN3A 1 [@grandeGenomewideDiscoverySomatic2019; @rossiCodingGenomeSplenic2012c]
SMARCA4 1 [@zhangGeneticHeterogeneityDiffuse2013; @nadeuGenomicEpigenomicInsights2020b; @krysiakRecurrentSomaticMutations2017b; @richterRecurrentMutationID32012a]
SOCS1 1, aSHM [@wenigerMutationsTumorSuppressor2006a; @morinFrequentMutationHistonemodifying2011]
SPEN 1 [@sarkozyMutationalLandscapeGray2021a; @rossiCodingGenomeSplenic2012c]
STAT3 1 [@ohgamiSTAT3MutationsAre2014]
STAT6 1 [@yildizActivatingSTAT6Mutations2015c; @ritzRecurrentMutationsSTAT62009a]
TAF1 1 [@spinaGeneticsNodalMarginal2016b; @morinMutationalStructuralAnalysis2013]
TBL1XR1 1 [@rossiCodingGenomeSplenic2012c; @mareschalWholeExomeSequencing2016]
TET2 1 [@albuquerqueEnhancingKnowledgeDiscovery2017a; @paneaWholeGenomeLandscape2019]
TMEM30A 1 [@morinFrequentMutationHistonemodifying2011]
TMSB4X 1, aSHM [@albuquerqueEnhancingKnowledgeDiscovery2017a]
TNFAIP3 1 [@schmitzTNFAIP3A20Tumor2009a; @rossiAlterationBIRC3Multiple2011a; @compagnoMutationsMultipleGenes2009a]
TNFRSF14 1 [@cheungAcquiredTNFRSF14Mutations2010a; @spinaGeneticsNodalMarginal2016b]
TOX 1 [@reddyGeneticFunctionalDrivers2017]
TP53 1 [@wildaInactivationARFMDM2p53Pathway2004; @rossiCodingGenomeSplenic2012c; @tiacciPervasiveMutationsJAKSTAT2018b; @beaLandscapeSomaticMutations2013; @morinFrequentMutationHistonemodifying2011]
TRRAP 1 [@rossiCodingGenomeSplenic2012c; @parryWholeExomeSequencing2013]
UBE2A 1 [@reddyGeneticFunctionalDrivers2017; @reichelFlowSortingExome2015a]
UNC5C 1
USP7 1 [@grandeGenomewideDiscoverySomatic2019]
VPS13B 1
WEE1 1 [@schmitzGeneticsPathogenesisDiffuse2018a; @reichelFlowSortingExome2015a]
XPO1 1 [@jardinRecurrentMutationsExportin2016a; @mareschalWholeExomeSequencing2016]
ZC3H12A 1 [@arthurGenomewideDiscoverySomatic2018]
ZFP36L1 1, aSHM [@morinFrequentMutationHistonemodifying2011; @reichelFlowSortingExome2015a; @paneaWholeGenomeLandscape2019]
ZNF292 1 [@zhangGeneticHeterogeneityDiffuse2013]
ZNF608 1, aSHM [@zhangGeneticHeterogeneityDiffuse2013; @krysiakRecurrentSomaticMutations2017b]

Tier 2 DLBCL genes

198 total

Gene Tier Relevant references
ABI3BP 2 [@morinMutationalStructuralAnalysis2013]
ADAMTS1 2 [@hubschmannMutationalMechanismsShaping2021b]
AICDA 2, aSHM [@arthurGenomewideDiscoverySomatic2018]
ANKRD12 2 [@hubschmannMutationalMechanismsShaping2021b]
ANKRD17 2 [@reddyGeneticFunctionalDrivers2017]
ARID1B 2 [@reddyGeneticFunctionalDrivers2017]
ARID5B 2 [@reddyGeneticFunctionalDrivers2017; @gomezUltraDeepSequencingReveals2023]
ATR 2 [@reddyGeneticFunctionalDrivers2017]
BCL11A 2, aSHM
BCOR 2 [@nadeuGenomicEpigenomicInsights2020b; @jalladesExomeSequencingIdentifies2017]
BCR 2, aSHM
BIRC3 2, aSHM [@dunsCharacterizationDLBCLPMBL2021b; @rossiAlterationBIRC3Multiple2011a; @arthurGenomewideDiscoverySomatic2018; @beaLandscapeSomaticMutations2013]
BLK 2, aSHM
BRINP3 2 [@reddyGeneticFunctionalDrivers2017]
BTBD3 2 [@reddyGeneticFunctionalDrivers2017]
CADPS2 2 [@hubschmannMutationalMechanismsShaping2021b]
CASP8 2 [@reddyGeneticFunctionalDrivers2017]
CBLB 2 [@reddyGeneticFunctionalDrivers2017]
CCL4 2 [@chapuyMolecularSubtypesDiffuse2018b]
CD22 2 [@reddyGeneticFunctionalDrivers2017]
CD274 2 [@morinFrequentMutationHistonemodifying2011]
CD36 2 [@pasqualucciAnalysisCodingGenome2011]
CD44 2, aSHM [@arthurGenomewideDiscoverySomatic2018]
CD74 2, aSHM [@arthurGenomewideDiscoverySomatic2018]
CDC73 2 [@reddyGeneticFunctionalDrivers2017; @loveGeneticLandscapeMutations2012]
CDH9 2 [@morinMutationalStructuralAnalysis2013]
CHD1 2 [@reddyGeneticFunctionalDrivers2017]
CHD8 2 [@grandeGenomewideDiscoverySomatic2019; @reddyGeneticFunctionalDrivers2017]
CHST2 2 [@reddyGeneticFunctionalDrivers2017]
CNOT2 2 [@hubschmannMutationalMechanismsShaping2021b]
CNTNAP5 2 [@morinMutationalStructuralAnalysis2013]
COQ7 2 [@chapuyMolecularSubtypesDiffuse2018b]
CRIP1 2 [@chapuyMolecularSubtypesDiffuse2018b]
DAZAP1 2 [@pararajalingamCodingNoncodingDrivers2020]
DCAF6 2 [@reddyGeneticFunctionalDrivers2017]
DDX10 2 [@reddyGeneticFunctionalDrivers2017]
DHX16 2 [@hubschmannMutationalMechanismsShaping2021b]
DICER1 2 [@reddyGeneticFunctionalDrivers2017]
DNAH5 2 [@morinMutationalStructuralAnalysis2013; @jalladesExomeSequencingIdentifies2017]
DNM2 2 [@hubschmannMutationalMechanismsShaping2021b]
DNMT3A 2 [@reddyGeneticFunctionalDrivers2017]
DOCK1 2 [@chapuyMolecularSubtypesDiffuse2018b]
DSG4 2 [@morinMutationalStructuralAnalysis2013]
EIF2AK3 2, aSHM
EZR 2, aSHM [@deschGenotypingCirculatingTumor2020]
FAM102A 2, aSHM
FAM38B 2 [@morinMutationalStructuralAnalysis2013]
FANK1 2, aSHM
FAT4 2 [@parryWholeExomeSequencing2013; @morinMutationalStructuralAnalysis2013; @zhangGenomicLandscapeMantle2014]
FCRL3 2, aSHM
FNBP1 2, aSHM
FNDC1 2 [@morinMutationalStructuralAnalysis2013]
FOXC1 2 [@schmitzGeneticsPathogenesisDiffuse2018a]
FOXP1 2, aSHM [@reddyGeneticFunctionalDrivers2017]
FUBP1 2 [@reddyGeneticFunctionalDrivers2017]
FUT5 2 [@chapuyMolecularSubtypesDiffuse2018b]
GABRA2 2 [@chapuyMolecularSubtypesDiffuse2018b]
GAK 2 [@hubschmannMutationalMechanismsShaping2021b]
GNAS 2 [@reddyGeneticFunctionalDrivers2017]
GOLGA5 2 [@reddyGeneticFunctionalDrivers2017]
GPC5 2 [@schmitzGeneticsPathogenesisDiffuse2018a]
GSG2 2 [@schmitzGeneticsPathogenesisDiffuse2018a]
HDAC7 2 [@morinMutationalStructuralAnalysis2013]
HIST1H2AG 2, aSHM [@morinMutationalStructuralAnalysis2013; @rossiCodingGenomeSplenic2012c; @paneaWholeGenomeLandscape2019; @krysiakRecurrentSomaticMutations2017b]
HLA-DMA 2
HLA-DQA1 2 [@hubschmannMutationalMechanismsShaping2021b]
HNF1B 2 [@pasqualucciAnalysisCodingGenome2011]
HNRNPD 2
HNRNPH1 2, noncoding [@pararajalingamCodingNoncodingDrivers2020]
HRAS 2 [@jalladesExomeSequencingIdentifies2017; @reddyGeneticFunctionalDrivers2017]
ID3 2 [@richterRecurrentMutationID32012a; @spinaGeneticsNodalMarginal2016b; @schmitzBurkittLymphomaPathogenesis2012]
IER2 2 [@morinMutationalStructuralAnalysis2013]
IFNGR1 2 [@morinMutationalStructuralAnalysis2013]
IGLL5 2, aSHM [@russler-germainMutationsAssociatedProgression2023b; @deschGenotypingCirculatingTumor2020; @paneaWholeGenomeLandscape2019]
IKBKB 2 [@reddyGeneticFunctionalDrivers2017; @rossiAlterationBIRC3Multiple2011a; @wienandGenomicAnalysesFlowsorted2019b]
IKBKE 2 [@hubschmannMutationalMechanismsShaping2021b]
IL16 2
IL6 2 [@chapuyMolecularSubtypesDiffuse2018b]
INO80 2 [@zhangGeneticHeterogeneityDiffuse2013]
IRAG2 2, aSHM
IRF1 2, aSHM [@hubschmannMutationalMechanismsShaping2021b]
JAK1 2 [@zhangGeneticHeterogeneityDiffuse2013; @mottokIntegrativeGenomicAnalysis2019b]
JAK3 2 [@zhangGeneticHeterogeneityDiffuse2013]
JUNB 2 [@reddyGeneticFunctionalDrivers2017; @mottokIntegrativeGenomicAnalysis2019b]
KCMF1 2 [@reddyGeneticFunctionalDrivers2017]
KLHL21 2 [@schmitzGeneticsPathogenesisDiffuse2018a]
LAMA5 2 [@schmitzGeneticsPathogenesisDiffuse2018a]
LAPTM5 2, aSHM [@hubschmannMutationalMechanismsShaping2021b]
LIN54 2 [@reddyGeneticFunctionalDrivers2017]
LPP 2, aSHM [@arthurGenomewideDiscoverySomatic2018]
LRP12 2 [@hubschmannMutationalMechanismsShaping2021b]
LRRN3 2 [@sarkozyMutationalLandscapeGray2021a; @morinMutationalStructuralAnalysis2013]
LYN 2 [@chapuyMolecularSubtypesDiffuse2018b]
MAGT1 2 [@reddyGeneticFunctionalDrivers2017]
MALAT1 2, aSHM [@arthurGenomewideDiscoverySomatic2018]
MAP2K1 2 [@shinBRAFV600EMAP2K12015; @louissaintPediatrictypeNodalFollicular2016a]
MAP4K4 2 [@reddyGeneticFunctionalDrivers2017]
MARK1 2 [@reddyGeneticFunctionalDrivers2017]
MCL1 2 [@paneaWholeGenomeLandscape2019; @reddyGeneticFunctionalDrivers2017; @dunsCharacterizationDLBCLPMBL2021b]
MECOM 2 [@reddyGeneticFunctionalDrivers2017]
MET 2 [@reddyGeneticFunctionalDrivers2017]
MIR142 2, aSHM [@grandeGenomewideDiscoverySomatic2019; @kwanhianMicroRNA142Mutated202012b]
MIR155HG 2, aSHM
MPDZ 2 [@reichelFlowSortingExome2015a; @morinMutationalStructuralAnalysis2013]
MSH2 2 [@reddyGeneticFunctionalDrivers2017]
MSH6 2 [@reddyGeneticFunctionalDrivers2017]
MYB 2 [@reddyGeneticFunctionalDrivers2017; @deschGenotypingCirculatingTumor2020]
MYBPC2 2 [@schmitzGeneticsPathogenesisDiffuse2018a]
MYO1E 2, aSHM
MYOM2 2 [@pasqualucciAnalysisCodingGenome2011]
N2RF2 2 [@hubschmannMutationalMechanismsShaping2021b]
NANOG 2 [@chapuyMolecularSubtypesDiffuse2018b]
NAV1 2 [@chapuyMolecularSubtypesDiffuse2018b]
NCOA3 2, aSHM
NCOR1 2 [@reddyGeneticFunctionalDrivers2017]
NCOR2 2 [@schmitzBurkittLymphomaPathogenesis2012; @spinaGeneticsNodalMarginal2016b; @sarkozyMutationalLandscapeGray2021a]
NEAT1 2, aSHM [@arthurGenomewideDiscoverySomatic2018]
NF1 2 [@reddyGeneticFunctionalDrivers2017]
NFKB1 2
NFKB2 2 [@reddyGeneticFunctionalDrivers2017; @mottokIntegrativeGenomicAnalysis2019b]
NLRC5 2
NLRP5 2 [@morinMutationalStructuralAnalysis2013]
NLRP8 2 [@chapuyMolecularSubtypesDiffuse2018b]
ODZ3 2 [@morinMutationalStructuralAnalysis2013]
P2RX5 2, aSHM [@morinMutationalStructuralAnalysis2013]
PAPOLG 2 [@schmitzGeneticsPathogenesisDiffuse2018a]
PASK 2 [@morinMutationalStructuralAnalysis2013]
PAX5 2, aSHM [@pasqualucciHypermutationMultipleProtooncogenes2001a]
PCBP1 2 [@schmitzBurkittLymphomaPathogenesis2012]
PCDHB11 2 [@morinMutationalStructuralAnalysis2013]
PCLO 2 [@lohrDiscoveryPrioritizationSomatic2012a]
PDE4DIP 2 [@chapuyMolecularSubtypesDiffuse2018b]
PDS5B 2 [@hubschmannMutationalMechanismsShaping2021b; @morinMutationalStructuralAnalysis2013]
PHF6 2 [@reddyGeneticFunctionalDrivers2017; @thomasGeneticSubgroupsInform2023]
PIK3CD 2 [@reddyGeneticFunctionalDrivers2017]
PIK3R1 2 [@zhangGeneticHeterogeneityDiffuse2013; @paneaWholeGenomeLandscape2019]
PKD1 2 [@morinMutationalStructuralAnalysis2013]
PNPO 2 [@hubschmannMutationalMechanismsShaping2021b]
POGZ 2 [@morinMutationalStructuralAnalysis2013]
PPP1R9B 2
PRKCB 2 [@morinMutationalStructuralAnalysis2013]
PRKDC 2 [@hubschmannMutationalMechanismsShaping2021b; @schmitzGeneticsPathogenesisDiffuse2018a]
PRPS1 2 [@chapuyMolecularSubtypesDiffuse2018b]
PTMA 2, aSHM
PTPN1 2, aSHM [@gunawardanaRecurrentSomaticMutations2014c]
PTPN23 2 [@morinMutationalStructuralAnalysis2013]
PTPN6 2 [@reddyGeneticFunctionalDrivers2017]
PTPRK 2 [@reddyGeneticFunctionalDrivers2017]
RAC2 2 [@hubschmannMutationalMechanismsShaping2021b; @paneaWholeGenomeLandscape2019]
RAD9A 2 [@chapuyMolecularSubtypesDiffuse2018b]
RARA 2 [@reddyGeneticFunctionalDrivers2017]
RCC 2, aSHM
RFTN1 2, aSHM [@dunsCharacterizationDLBCLPMBL2021b; @arthurGenomewideDiscoverySomatic2018]
RFXAP 2
RHEX 2, aSHM
RHOH 2, aSHM [@pasqualucciHypermutationMultipleProtooncogenes2001a]
RUBCNL 2, aSHM
RUNX1 2 [@reddyGeneticFunctionalDrivers2017]
SAMD9L 2 [@morinMutationalStructuralAnalysis2013]
SARM1 2 [@morinMutationalStructuralAnalysis2013]
SEL1L3 2, aSHM
SEPTIN9 2, aSHM
SERPINA9 2, aSHM [@arthurGenomewideDiscoverySomatic2018]
SETD2 2 [@zhangGeneticHeterogeneityDiffuse2013]
SETD5 2 [@reddyGeneticFunctionalDrivers2017; @tiacciPervasiveMutationsJAKSTAT2018b]
SIAH2 2 [@reichelFlowSortingExome2015a; @hubschmannMutationalMechanismsShaping2021b]
SLC34A2 2 [@hubschmannMutationalMechanismsShaping2021b]
SMEK1 2 [@chapuyMolecularSubtypesDiffuse2018b]
SRRM2 2 [@russler-germainMutationsAssociatedProgression2023b; @morinMutationalStructuralAnalysis2013]
ST6GAL1 2, aSHM [@arthurGenomewideDiscoverySomatic2018]
STAT5B 2 [@zhangGeneticHeterogeneityDiffuse2013; @tiacciPervasiveMutationsJAKSTAT2018b]
SYK 2 [@reddyGeneticFunctionalDrivers2017]
SYPL1 2 [@morinMutationalStructuralAnalysis2013]
TAP1 2 [@schmitzGeneticsPathogenesisDiffuse2018a]
TBC1D4 2, aSHM [@arthurGenomewideDiscoverySomatic2018]
TCL1A 2, aSHM [@grandeGenomewideDiscoverySomatic2019]
TGFBR2 2 [@reddyGeneticFunctionalDrivers2017]
TIPARP 2 [@reddyGeneticFunctionalDrivers2017]
TLR2 2 [@chapuyMolecularSubtypesDiffuse2018b; @beaLandscapeSomaticMutations2013]
TRAF3 2 [@rossiAlterationBIRC3Multiple2011a; @ottoGeneticLesionsTRAF32012a; @pasqualucciAnalysisCodingGenome2011]
TRAF6 2 [@hubschmannMutationalMechanismsShaping2021b]
TRIP12 2
UBE2J1 2, aSHM
UBR5 2 [@pararajalingamCodingNoncodingDrivers2020; @zhangGeneticHeterogeneityDiffuse2013]
UNC5B 2 [@hubschmannMutationalMechanismsShaping2021b]
UNC5D 2
WAC 2 [@rossiCodingGenomeSplenic2012c; @reddyGeneticFunctionalDrivers2017]
WDFY3 2 [@morinMutationalStructuralAnalysis2013]
WNK1 2 [@hubschmannMutationalMechanismsShaping2021b; @thomasGeneticSubgroupsInform2023; @jalladesExomeSequencingIdentifies2017]
XBP1 2, aSHM
YY1 2 [@reddyGeneticFunctionalDrivers2017]
ZBTB7A 2 [@burkhardtClinicalRelevanceMolecular2022b; @reddyGeneticFunctionalDrivers2017]
ZCCHC7 2, aSHM [@arthurGenomewideDiscoverySomatic2018]
ZEB2 2 [@zhangGeneticHeterogeneityDiffuse2013]
ZFAT 2 [@reddyGeneticFunctionalDrivers2017]
ZFX 2 [@reddyGeneticFunctionalDrivers2017]
ZNF217 2 [@hubschmannMutationalMechanismsShaping2021b; @reichelFlowSortingExome2015a]
ZNF423 2 [@chapuyMolecularSubtypesDiffuse2018b]

References

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