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rdmorin edited this page Jun 21, 2024 · 18 revisions

bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

SETD5

History

%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%
timeline
    title Publication timing
      2017-10-10 : Reddy : DLBCL
      2018-05-31 : Tiacci : PMBL
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Relevance tier by entity

Entity Tier Description
PMBL 2 relevance in PMBL/cHL/GZL not firmly established[@tiacciPervasiveMutationsJAKSTAT2018b]
DLBCL 2 relevance in DLBCL not firmly established[@reddyGeneticFunctionalDrivers2017]

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
DLBCL GAMBL genomes 2.49
DLBCL Schmitz cohort 5.32
DLBCL Reddy cohort 3.20
DLBCL Chapuy cohort 2.14

Mutation pattern and selective pressure estimates

Entity aSHM Significant selection dN/dS (missense) dN/dS (nonsense)
BL No No 0.000 0.000
DLBCL No No 0.841 32.108
FL No No 2.236 0.000

Warning

Mutations in this gene were reported to be inflated in the original results according to Dreval K

View coding variants in ProteinPaint hg19 or hg38

View all variants in GenomePaint hg19 or hg38

SETD5 Expression

Representative Mutations

Rating ★ ★ ★ ★ ★

Rating ★ ★ ☆ ☆ ☆

All Mutations

Reddy_2084T Reddy_2130T Reddy_2154T Reddy_2226T Reddy_2249T Reddy_2306T Reddy_2478T Reddy_2522T Reddy_2539T Reddy_2547T Reddy_2559T Reddy_2561T Reddy_2636T Reddy_2655T Reddy_2671T Reddy_2681T Reddy_2691T Reddy_2905T Reddy_2912T Reddy_2949T Reddy_2956T Reddy_2957T Reddy_3389T Reddy_3399T Reddy_3405T Reddy_3489T Reddy_3597T Reddy_3643T Reddy_3692T Reddy_3727T Reddy_3748T Reddy_3754T Reddy_3834T Reddy_3859T Reddy_3898T Reddy_3923T Reddy_3937T Reddy_3960T Reddy_3973T Reddy_3984T Reddy_3992T Reddy_3995T Reddy_695T

References

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