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rdmorin edited this page Jul 3, 2024 · 17 revisions

bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

WAC

<<Warn("The variants reported in this gene in DLBCL failed QC")>>

History

%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%
timeline
    title Publication timing
      2012-08-27 : Rossi : MZL
      2017-10-10 : Reddy : DLBCL
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Relevance tier by entity

Entity Tier Description
MZL 2 relevance in MZL not firmly established[@rossiCodingGenomeSplenic2012c]
DLBCL 3 Retired, Failed QC[@reddyGeneticFunctionalDrivers2017]

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
DLBCL GAMBL genomes 2.68
DLBCL Schmitz cohort 3.40
DLBCL Reddy cohort 1.20
DLBCL Chapuy cohort 1.28

Mutation pattern and selective pressure estimates

Entity aSHM Significant selection dN/dS (missense) dN/dS (nonsense)
BL No No 0.957 0
DLBCL No No 1.590 0
FL No No 0.000 0

View coding variants in ProteinPaint hg19 or hg38

View all variants in GenomePaint hg19 or hg38

WAC Expression

All Mutations

Reddy_2232T Reddy_2619T Reddy_2698T Reddy_2769T Reddy_2791T Reddy_2892T Reddy_2898T Reddy_2919T Reddy_2931T Reddy_2933T Reddy_2934T Reddy_2936T Reddy_2953T Reddy_2999T Reddy_3456T Reddy_3480T Reddy_3653T Reddy_3704T Reddy_3721T Reddy_3750T Reddy_3758T Reddy_3977T

References

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