loveGeneticLandscapeMutations2012
| Entity | Tier 1 genes | Tier 2 genes | Tier 3 genes |
|---|---|---|---|
| BL | 5 | 7 | 48 |
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sankey-beta
This study, New Tier 1, 5
New Tier 1, BL Tier 1, 5
This study, New Tier 2, 7
New Tier 2, BL Tier 2, 7
This study, New Tier 3, 48
New Tier 3, BL Tier 3, 48
All other BL studies, BL Tier 1, 27
All other BL studies, BL Tier 2, 65
All other BL studies, BL Tier 3, 22
| New gene | BL tier | Average variant quality | QC outcome |
|---|---|---|---|
| ARID1A | 1 | ||
| BCL6 | 1 | ★ ★ ★ ★ ☆ | PASS |
| CREBBP | 1 | ★ ★ ★ ★ ☆ | PASS |
| GNA13 | 1 | ||
| PTEN | 1 |
| New gene | BL tier | Average variant quality | QC outcome |
|---|---|---|---|
| CARD4 | 2 | ★ ★ ★ ★ ☆ | PASS |
| CDC73 | 2 | ★ ★ ★ ☆ ☆ | PASS |
| EZH2 | 2 | ★ ★ ★ ★ ★ | PASS |
| GGTLA4 | 2 | ★ ★ ★ ★ ☆ | PASS |
| NBEAL1 | 2 | ★ ★ ★ ★ ☆ | PASS |
| P2RY2 | 2 | ★ ★ ★ ★ ☆ | PASS |
| RANBP6 | 2 | ★ ★ ★ ★ ★ | PASS |
| New gene | BL tier | Average variant quality | QC outcome |
|---|---|---|---|
| ACAD9 | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| ACE | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| ATP2C2 | 3 | ★ ★ ☆ ☆ ☆ | FAIL |
| BRAF | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| BRD4 | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| BTG2 | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| C6orf27 | 3 | Germline | FAIL |
| CAD | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| CCT6B | 3 | Germline | FAIL |
| CDH17 | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| COL4A2 | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| CYB5D1 | 3 | ★ ★ ☆ ☆ ☆ | FAIL |
| CYP4F22 | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| DLGAP1 | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| DTX1 | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| EIF2C4 | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| EML2 | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| ENTPD3 | 3 | ★ ★ ☆ ☆ ☆ | FAIL |
| EPHB2 | 3 | ★ ★ ☆ ☆ ☆ | FAIL |
| FAM129B | 3 | ★ ★ ☆ ☆ ☆ | FAIL |
| FGFR3 | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| FTCD | 3 | Germline | FAIL |
| GRIK5 | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| ICK | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| ITPR3 | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| KIFC3 | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| MAP3K6 | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| MYH10 | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| NOTCH1 | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| NRXN2 | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| PC | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| POLRMT | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| POR | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| PRSS22 | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| PTPRN | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| RBP3 | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| RET | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| SALL3 | 3 | ★ ★ ☆ ☆ ☆ | FAIL |
| SAPS2 | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| SBF1 | 3 | ★ ★ ☆ ☆ ☆ | FAIL |
| SF3B1 | 3 | ★ ★ ★ ★ ☆ | FAIL |
| SHANK1 | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| SLC29A2 | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| SYNGAP1 | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| TBC1D9B | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| TIGD6 | 3 | ★ ☆ ☆ ☆ ☆ | FAIL |
| TPST2 | 3 | ☆ ☆ ☆ ☆ ☆ | FAIL |
| ZNF229 | 3 | Germline | FAIL |
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