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rdmorin edited this page Jul 3, 2024 · 18 revisions

bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

MYB

<<Warn("The variants reported in this gene in DLBCL failed QC")>>

History

%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%
timeline
    title Publication timing
      2017-10-10 : Reddy : DLBCL
      2019-08-20 : Desch : PMBL
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Relevance tier by entity

Entity Tier Description
PMBL 2 relevance in PMBL/cHL/GZL not firmly established[@deschGenotypingCirculatingTumor2020]
DLBCL 3 Retired, Failed QC

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
DLBCL GAMBL genomes 0.57
DLBCL Schmitz cohort 2.13
DLBCL Reddy cohort 1.10
DLBCL Chapuy cohort 0.85

Mutation pattern and selective pressure estimates

Entity aSHM Significant selection dN/dS (missense) dN/dS (nonsense)
BL No No 2.555 0
DLBCL No No 0.000 0
FL No No 2.377 0

View coding variants in ProteinPaint hg19 or hg38

View all variants in GenomePaint hg19 or hg38

MYB Expression

All Mutations

Reddy_2120T Reddy_2137T Reddy_2140T Reddy_2190T Reddy_2450T Reddy_2680T Reddy_2895T Reddy_2935T Reddy_3394T Reddy_3485T Reddy_3755T Reddy_3766T Reddy_3779T Reddy_3783T Reddy_3846T Reddy_3852T Reddy_3948T Reddy_3961T Reddy_3978T Reddy_3990T

References

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