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rdmorin edited this page Jun 20, 2024 · 14 revisions

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PLCG2

History

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timeline
    title Publication timing
      2019-09-26 : Panea : BL
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Relevance tier by entity

Entity Tier Description
BL 2 relevance in BL not firmly established[@paneaWholeGenomeLandscape2019]

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
BL GAMBL genomes+capture 3.0
BL Thomas cohort 0.8
BL Panea cohort 10.9

Mutation pattern and selective pressure estimates

Entity aSHM Significant selection dN/dS (missense) dN/dS (nonsense)
BL No No 0.800 0.000
DLBCL No No 2.213 14.094
FL No No 1.491 0.000

PLCG2 Hotspots

Chromosome Coordinate (hg19) ref>alt HGVSp
chr16 81819719 C>A T42N

View coding variants in ProteinPaint hg19 or hg38

View all variants in GenomePaint hg19 or hg38

PLCG2 Expression

References

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