WNK1
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timeline
title Publication timing
2017-07-27 : Jallades : MZL
2021-05-05 : Hübschmann : DLBCL
2023-02-03 : Thomas : BL
| Entity | Tier | Description |
|---|---|---|
 |
2 | relevance in MZL not firmly established[@jalladesExomeSequencingIdentifies2017] |
 |
1 | high-confidence BL gene [@thomasGeneticSubgroupsInform2023] |
 |
2 | relevance in DLBCL not firmly established[@hubschmannMutationalMechanismsShaping2021b] |
| Entity | source | frequency (%) |
|---|---|---|
| BL | GAMBL genomes+capture | 6.70 |
| BL | Thomas cohort | 6.80 |
| BL | Panea cohort | 11.90 |
| DLBCL | GAMBL genomes | 4.59 |
| DLBCL | Schmitz cohort | 5.11 |
| DLBCL | Reddy cohort | 3.70 |
| DLBCL | Chapuy cohort | 2.14 |
| Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
|---|---|---|---|---|
| BL | No | No | 3.429 | 0 |
| DLBCL | No | No | 1.812 | 0 |
| FL | No | No | 3.487 | 0 |
| Chromosome | Coordinate (hg19) | ref>alt | HGVSp |
|---|---|---|---|
| chr12 | 968467 | G>A | R486Q |
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38
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