IGLL5
| Entity | Tier | Description |
|---|---|---|
 |
2 | relevance in PMBL/cHL/GZL not firmly established |
 |
2-a | aSHM target; Although recurrent, the relevance of mutations in BL is tenuous |
 |
2-a | aSHM target; Although recurrent, the relevance of mutations in DLBCL is tenuous |
 |
2-a | aSHM target; Although recurrent, the relevance of mutations in FL is tenuous |
| Entity | source | frequency (%) |
|---|---|---|
| BL | GAMBL genomes+capture | 26.33 |
| BL | Thomas cohort | 25.00 |
| BL | Panea cohort | 23.80 |
| DLBCL | GAMBL genomes | 41.49 |
| DLBCL | Schmitz cohort | 35.96 |
| DLBCL | Reddy cohort | 16.12 |
| DLBCL | Chapuy cohort | 8.97 |
| FL | GAMBL genomes | 35.33 |
| Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
|---|---|---|---|---|
| BL | Yes | Yes | 7.850 | 3.210 |
| DLBCL | Yes | Yes | 3.376 | 5.315 |
| FL | Yes | Yes | 4.830 | 9.846 |
| chr_name | hg19_start | hg19_end | region | regulatory_comment |
|---|---|---|---|---|
| chr22 | 23229554 | 23232042 | TSS | NA |
Note
First described in FL in 2023 by Russler-Germain DA
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38
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