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rdmorin edited this page Jun 21, 2024 · 17 revisions

bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

SYK

<<Warn("The variants reported in this gene in DLBCL failed QC")>>

History

%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%
timeline
    title Publication timing
      2017-10-10 : Reddy : DLBCL
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Relevance tier by entity

Entity Tier Description
DLBCL 2-F failed QC[@reddyGeneticFunctionalDrivers2017]

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
DLBCL GAMBL genomes 1.53
DLBCL Schmitz cohort 2.34
DLBCL Reddy cohort 0.80
DLBCL Chapuy cohort 0.43

Mutation pattern and selective pressure estimates

Entity aSHM Significant selection dN/dS (missense) dN/dS (nonsense)
BL No No 2.281 0.00
DLBCL No No 3.818 12.94
FL No No 0.000 0.00

View coding variants in ProteinPaint hg19 or hg38

View all variants in GenomePaint hg19 or hg38

SYK Expression

All Mutations

Reddy_2079T Reddy_2228T Reddy_2261T Reddy_2599T Reddy_2761T Reddy_2766T Reddy_2874T Reddy_2922T Reddy_3610T Reddy_3627T Reddy_3637T Reddy_3698T Reddy_683T

References

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